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The map label for this gene is udg [H]

Identifier: 119357336

GI number: 119357336

Start: 1741870

End: 1743207

Strand: Reverse

Name: udg [H]

Synonym: Cpha266_1534

Alternate gene names: 119357336

Gene position: 1743207-1741870 (Counterclockwise)

Preceding gene: 119357337

Following gene: 119357332

Centisome position: 55.62

GC content: 44.92

Gene sequence:

>1338_bases
ATGAAAATAACGATTTTCGGCTCTGGCTACGTTGGACTTGTTACCGGTGCATGTTTTGCAGAAGTTGGTAATGATGTTTT
GTGTGTTGATATTGACCATCAGAAAATCCAAAGACTGGAACAGGGAGAAATTCCTATCTACGAACCAGGTCTTGAAGCGC
TTGTTGTTGAAAATACCAGTAAAGGCCGCCTGAAATTTACTACTGATATCAAAAAAGGCGTTGATTTCGGACTCTATCAG
TTTATCGCGGTCGGAACGCCACCTGATGAAGATGGTTCTGCCGATTTGCGACACGTGTTAAGCGTTGCCGAGAGTATCGG
TACATACATGGAGGAGTATCGCATTATCATCAACAAATCAACCGTGCCTGTTGGTACTGCTGATCTTGTAAAGGAAAAAG
TCACTTCCGTGTTGAAAGAGAGGAATGTTATTATGGACTTTGACGTCGTCTCAAATCCCGAATTTCTCAAGGAAGGAGAC
GCAGTCAATGATTTCATGAAGCCGGAGCGAATTGTTATCGGAGTTGATAATCCCAGAACGAAAGAGCTTTTGAGATTTCT
CTATTCCCCTTTCAACCGCAGTCATGAGCGTTTTATTGCCATGGATATTCGTTCTGCAGAGTTGACTAAATATGCGGCAA
ATTCCATGCTTGCAACGAAAATCAGCTTTATGAACGAAATTGCCAACATTGCAGAACGAGTAGGCGCTGATATCGAATCT
GTCAGAAAAGGTATAGGTTCCGACTCCCGAATCGGCTTTTCGTTTATATACCCCGGTGTTGGTTATGGCGGCTCCTGTTT
TCCGAAAGATGTGCAGGCTCTTGAAAGAACATCGCGCAAATTCGGTTATGACGCAAGGATACTGCAGGCAGTTGAGGCGG
TCAATAACGATCAGAAAGGCACAATTGTCAAAAAAATAATCGATCATTTTAATGGCGATATCAAGGGAAAGGTGTTTGCG
GTATGGGGACTTGCTTTTAAACCGAATACCGATGATATGCGTGAAGCGCCCAGCCGTACGGTAATTGAGGCTCTGTGGAA
GGAAGGCGCTACAGTTAAAGCCTATGATCCGGTTGCAATGGAAGAGGCCGCCAGAATTTATGGAGAGCGTGATGATCTGA
AGTATGCAGCCAACCCGGAAGAGGCGATAATCGGTGCGGATGCTCTTGTTGTGCTTACTGAGTGGCTTGTTTTTCGCAGT
CCCGATTTTGAGATGATCAAGAGGGAGCTTCGTCAACCGGTTGTGTTTGACGGAAGAAATATTTACAGTCCTGAGTATAT
GGAACAGGCAGGGTTTGTCTATTACTCTGTAGGACGCAGACCGCGGGGTCTCAATTGA

Upstream 100 bases:

>100_bases
AGGAACAAATACATAGCGATGTCCTGGAGTTGTTTTTGTTTCTTCACAGTTCCTTGAGGAGTATATTGGCATTAAAAAAA
TAACTATTACAGAATAACTG

Downstream 100 bases:

>100_bases
ACGTTTATCTCCAGAGCTTATAACAGTGATGCAGCGGCCCGCTTCCCTTACCGATAAGGTAAGCGGCACCTGCCTCTAAA
GCATCATAAGTGTAAGATTT

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MKITIFGSGYVGLVTGACFAEVGNDVLCVDIDHQKIQRLEQGEIPIYEPGLEALVVENTSKGRLKFTTDIKKGVDFGLYQ
FIAVGTPPDEDGSADLRHVLSVAESIGTYMEEYRIIINKSTVPVGTADLVKEKVTSVLKERNVIMDFDVVSNPEFLKEGD
AVNDFMKPERIVIGVDNPRTKELLRFLYSPFNRSHERFIAMDIRSAELTKYAANSMLATKISFMNEIANIAERVGADIES
VRKGIGSDSRIGFSFIYPGVGYGGSCFPKDVQALERTSRKFGYDARILQAVEAVNNDQKGTIVKKIIDHFNGDIKGKVFA
VWGLAFKPNTDDMREAPSRTVIEALWKEGATVKAYDPVAMEEAARIYGERDDLKYAANPEEAIIGADALVVLTEWLVFRS
PDFEMIKRELRQPVVFDGRNIYSPEYMEQAGFVYYSVGRRPRGLN

Sequences:

>Translated_445_residues
MKITIFGSGYVGLVTGACFAEVGNDVLCVDIDHQKIQRLEQGEIPIYEPGLEALVVENTSKGRLKFTTDIKKGVDFGLYQ
FIAVGTPPDEDGSADLRHVLSVAESIGTYMEEYRIIINKSTVPVGTADLVKEKVTSVLKERNVIMDFDVVSNPEFLKEGD
AVNDFMKPERIVIGVDNPRTKELLRFLYSPFNRSHERFIAMDIRSAELTKYAANSMLATKISFMNEIANIAERVGADIES
VRKGIGSDSRIGFSFIYPGVGYGGSCFPKDVQALERTSRKFGYDARILQAVEAVNNDQKGTIVKKIIDHFNGDIKGKVFA
VWGLAFKPNTDDMREAPSRTVIEALWKEGATVKAYDPVAMEEAARIYGERDDLKYAANPEEAIIGADALVVLTEWLVFRS
PDFEMIKRELRQPVVFDGRNIYSPEYMEQAGFVYYSVGRRPRGLN
>Mature_445_residues
MKITIFGSGYVGLVTGACFAEVGNDVLCVDIDHQKIQRLEQGEIPIYEPGLEALVVENTSKGRLKFTTDIKKGVDFGLYQ
FIAVGTPPDEDGSADLRHVLSVAESIGTYMEEYRIIINKSTVPVGTADLVKEKVTSVLKERNVIMDFDVVSNPEFLKEGD
AVNDFMKPERIVIGVDNPRTKELLRFLYSPFNRSHERFIAMDIRSAELTKYAANSMLATKISFMNEIANIAERVGADIES
VRKGIGSDSRIGFSFIYPGVGYGGSCFPKDVQALERTSRKFGYDARILQAVEAVNNDQKGTIVKKIIDHFNGDIKGKVFA
VWGLAFKPNTDDMREAPSRTVIEALWKEGATVKAYDPVAMEEAARIYGERDDLKYAANPEEAIIGADALVVLTEWLVFRS
PDFEMIKRELRQPVVFDGRNIYSPEYMEQAGFVYYSVGRRPRGLN

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=464, Percent_Identity=33.6206896551724, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI296040438, Length=366, Percent_Identity=33.6065573770492, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI296040443, Length=325, Percent_Identity=33.8461538461538, Blast_Score=174, Evalue=1e-43,
Organism=Escherichia coli, GI1788340, Length=366, Percent_Identity=27.8688524590164, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI48994968, Length=442, Percent_Identity=26.0180995475113, Blast_Score=130, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17560350, Length=467, Percent_Identity=34.9036402569593, Blast_Score=238, Evalue=3e-63,
Organism=Drosophila melanogaster, GI17136908, Length=466, Percent_Identity=33.9055793991416, Blast_Score=240, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 49698; Mature: 49698

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITIFGSGYVGLVTGACFAEVGNDVLCVDIDHQKIQRLEQGEIPIYEPGLEALVVENTS
CEEEEEECCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHCCCCCEECCCCCEEEEECCC
KGRLKFTTDIKKGVDFGLYQFIAVGTPPDEDGSADLRHVLSVAESIGTYMEEYRIIINKS
CCCEEEEECHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECC
TVPVGTADLVKEKVTSVLKERNVIMDFDVVSNPEFLKEGDAVNDFMKPERIVIGVDNPRT
CCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHCCCHHHHHCCCCEEEEECCCCCH
KELLRFLYSPFNRSHERFIAMDIRSAELTKYAANSMLATKISFMNEIANIAERVGADIES
HHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRKGIGSDSRIGFSFIYPGVGYGGSCFPKDVQALERTSRKFGYDARILQAVEAVNNDQKG
HHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
TIVKKIIDHFNGDIKGKVFAVWGLAFKPNTDDMREAPSRTVIEALWKEGATVKAYDPVAM
HHHHHHHHHHCCCCCCEEEEEEEEEECCCCCHHHHCCHHHHHHHHHHCCCEEEECCCHHH
EEAARIYGERDDLKYAANPEEAIIGADALVVLTEWLVFRSPDFEMIKRELRQPVVFDGRN
HHHHHHHCCCCCCCCCCCCCHHEECCHHHHHHHHHHHHCCCCHHHHHHHHCCCEEECCCC
IYSPEYMEQAGFVYYSVGRRPRGLN
CCCHHHHHHCCEEEEECCCCCCCCC
>Mature Secondary Structure
MKITIFGSGYVGLVTGACFAEVGNDVLCVDIDHQKIQRLEQGEIPIYEPGLEALVVENTS
CEEEEEECCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHCCCCCEECCCCCEEEEECCC
KGRLKFTTDIKKGVDFGLYQFIAVGTPPDEDGSADLRHVLSVAESIGTYMEEYRIIINKS
CCCEEEEECHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECC
TVPVGTADLVKEKVTSVLKERNVIMDFDVVSNPEFLKEGDAVNDFMKPERIVIGVDNPRT
CCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHCCCHHHHHCCCCEEEEECCCCCH
KELLRFLYSPFNRSHERFIAMDIRSAELTKYAANSMLATKISFMNEIANIAERVGADIES
HHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRKGIGSDSRIGFSFIYPGVGYGGSCFPKDVQALERTSRKFGYDARILQAVEAVNNDQKG
HHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
TIVKKIIDHFNGDIKGKVFAVWGLAFKPNTDDMREAPSRTVIEALWKEGATVKAYDPVAM
HHHHHHHHHHCCCCCCEEEEEEEEEECCCCCHHHHCCHHHHHHHHHHCCCEEEECCCHHH
EEAARIYGERDDLKYAANPEEAIIGADALVVLTEWLVFRSPDFEMIKRELRQPVVFDGRN
HHHHHHHCCCCCCCCCCCCCHHEECCHHHHHHHHHHHHCCCCHHHHHHHHCCCEEECCCC
IYSPEYMEQAGFVYYSVGRRPRGLN
CCCHHHHHHCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]