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The map label for this gene is ycgM [H]

Identifier: 119357146

GI number: 119357146

Start: 1530433

End: 1531152

Strand: Direct

Name: ycgM [H]

Synonym: Cpha266_1335

Alternate gene names: 119357146

Gene position: 1530433-1531152 (Clockwise)

Preceding gene: 119357140

Following gene: 119357147

Centisome position: 48.83

GC content: 49.03

Gene sequence:

>720_bases
ATGCCACAATACATCGATCCGTCATCGATTACGACCGGCACCATCTTCTGTGTCGCAAAAAACTATCCTGAACATGCCAG
AGAGATGCTGCTATGGGATGATCCGACAACAGAGGGAACTCCTCTGCCTGATGAAGAACCGGTTATTTTTCTTAAGCCCC
CATCGGCAATTTCAACCGACGGCATTACCGGAATTCCATCCTTCAACGGAAAGCCTGTTTCAGGCAATCTGCATTACGAA
GCCGAACTGATACTACTTATCGGCAGGGATTGCGAAAACTGCTCTCTTCATGAGGCATTGCAAGCGGTAAAAGGCTACGG
GATAGGGCTGGACATGACGCTCAGGGATGTGCAGCTTGCTGCAAAAAAAGAGGGCAACCCATGGCTGAAAAGCAAAGGGT
TCAGAAACAGCGCTCTGATTTCAGAGATCATTCCCCGTGCTGAAGCCGGAAACTGGCAGGATTTAGAGTTTATTCTTGAA
CACAACGGAAAGCGCGTTCAGCACGGAAAGGCCGCCTCAATGATCTTTTCGCCGATCTATCTTGTCCATTATTTATCGTA
TCTTTACGGTCTCCGCCGCGGGGATCTCGTTTTTACCGGAACGCCGTCAGGAGTTGGCCGTGTTGTACCTGGAGATCATC
TGAAAGCAACCCTTTTTCACAGAGAGATTTTGTCTGATACCGATGCCGCAATGCTCGCCCTTAAAGCGTGCGTCATATAA

Upstream 100 bases:

>100_bases
GTTATTATCCTTGTGAAGTAAACGACAAGCCGGAAAGGTTGGACATAAAAACAAATGATTTTACATTGCTGTAACAAATA
AACGACCAATTCCCGTCCCT

Downstream 100 bases:

>100_bases
AAAAGCATGCTTTAACTCCATAACTATTCCATTTTATCATGAGCACCATTTTTCAAAACGCCCATATCATCAACCCACAA
AGCAACCTTGATTATACCGG

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MPQYIDPSSITTGTIFCVAKNYPEHAREMLLWDDPTTEGTPLPDEEPVIFLKPPSAISTDGITGIPSFNGKPVSGNLHYE
AELILLIGRDCENCSLHEALQAVKGYGIGLDMTLRDVQLAAKKEGNPWLKSKGFRNSALISEIIPRAEAGNWQDLEFILE
HNGKRVQHGKAASMIFSPIYLVHYLSYLYGLRRGDLVFTGTPSGVGRVVPGDHLKATLFHREILSDTDAAMLALKACVI

Sequences:

>Translated_239_residues
MPQYIDPSSITTGTIFCVAKNYPEHAREMLLWDDPTTEGTPLPDEEPVIFLKPPSAISTDGITGIPSFNGKPVSGNLHYE
AELILLIGRDCENCSLHEALQAVKGYGIGLDMTLRDVQLAAKKEGNPWLKSKGFRNSALISEIIPRAEAGNWQDLEFILE
HNGKRVQHGKAASMIFSPIYLVHYLSYLYGLRRGDLVFTGTPSGVGRVVPGDHLKATLFHREILSDTDAAMLALKACVI
>Mature_238_residues
PQYIDPSSITTGTIFCVAKNYPEHAREMLLWDDPTTEGTPLPDEEPVIFLKPPSAISTDGITGIPSFNGKPVSGNLHYEA
ELILLIGRDCENCSLHEALQAVKGYGIGLDMTLRDVQLAAKKEGNPWLKSKGFRNSALISEIIPRAEAGNWQDLEFILEH
NGKRVQHGKAASMIFSPIYLVHYLSYLYGLRRGDLVFTGTPSGVGRVVPGDHLKATLFHREILSDTDAAMLALKACVI

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI215422413, Length=204, Percent_Identity=37.7450980392157, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI13654274, Length=204, Percent_Identity=37.2549019607843, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI66348062, Length=204, Percent_Identity=37.7450980392157, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI156231349, Length=193, Percent_Identity=27.979274611399, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI40786394, Length=193, Percent_Identity=26.9430051813472, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1787428, Length=206, Percent_Identity=40.2912621359223, Blast_Score=141, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17557057, Length=204, Percent_Identity=33.8235294117647, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6324161, Length=242, Percent_Identity=30.5785123966942, Blast_Score=102, Evalue=7e-23,
Organism=Drosophila melanogaster, GI28571789, Length=181, Percent_Identity=33.7016574585635, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28572127, Length=209, Percent_Identity=26.7942583732057, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 26245; Mature: 26114

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQYIDPSSITTGTIFCVAKNYPEHAREMLLWDDPTTEGTPLPDEEPVIFLKPPSAISTD
CCCCCCCCCCCCEEEEEEECCCCHHHHHEEEECCCCCCCCCCCCCCCEEEECCCCCCCCC
GITGIPSFNGKPVSGNLHYEAELILLIGRDCENCSLHEALQAVKGYGIGLDMTLRDVQLA
CCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCEEHHHHHHH
AKKEGNPWLKSKGFRNSALISEIIPRAEAGNWQDLEFILEHNGKRVQHGKAASMIFSPIY
HCCCCCCCHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHCCCCEECCCCHHHHHHHHHH
LVHYLSYLYGLRRGDLVFTGTPSGVGRVVPGDHLKATLFHREILSDTDAAMLALKACVI
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure 
PQYIDPSSITTGTIFCVAKNYPEHAREMLLWDDPTTEGTPLPDEEPVIFLKPPSAISTD
CCCCCCCCCCCEEEEEEECCCCHHHHHEEEECCCCCCCCCCCCCCCEEEECCCCCCCCC
GITGIPSFNGKPVSGNLHYEAELILLIGRDCENCSLHEALQAVKGYGIGLDMTLRDVQLA
CCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCEEHHHHHHH
AKKEGNPWLKSKGFRNSALISEIIPRAEAGNWQDLEFILEHNGKRVQHGKAASMIFSPIY
HCCCCCCCHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHCCCCEECCCCHHHHHHHHHH
LVHYLSYLYGLRRGDLVFTGTPSGVGRVVPGDHLKATLFHREILSDTDAAMLALKACVI
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]