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The map label for this gene is fadR

Identifier: 117920082

GI number: 117920082

Start: 1924865

End: 1925590

Strand: Direct

Name: fadR

Synonym: Shewana3_1635

Alternate gene names: 117920082

Gene position: 1924865-1925590 (Clockwise)

Preceding gene: 117920078

Following gene: 117920087

Centisome position: 38.71

GC content: 46.69

Gene sequence:

>726_bases
ATGATTATCAATGCCAAAGGACCTGCAAGTTTTGCAGAGAAGTATATTGTAAGATCGATTTGGGAAAATAAGTTTCCCCC
AGGGTCCATTTTACCGGCTGAACGTGAGCTTTCTGAATTAATTGGCGTTACACGTACTACCTTGCGTGAAGTGCTGCAAC
GCTTAGCCCGTGATGGTTGGTTGAAAATTCAACATGGTAAACCGACTCGGGTGAACAATTTTTGGGAAACCTCGGGCCTT
AACATTCTTGAGACGATTGCGGATCTCAACCCGGAAGGTTTCCCTGTGCTGGTGGACCAATTGCTGTCGGCTCGCACCAA
TGTCAGTGCGATTTACTTCCGTGGCGCACTGCGCAACAGCCCAGATACCGCCGTTGAAGTCTTAGGACAAATTCACCAAT
TAGAAGATACGGCCGAATCCTTCGCCGAGTATGATTACCTGTTGCACCACACCTTGGCCTTCTCTTCTGGTAATCCACTG
TACGTGTTGATTTTAAACGGCTTTAAAGGTTTGTATAGCCGGGTGGGTCGTTACTATTTCAGTAGTCCTGAGGCGCGTCA
GTTAGCGCTGAACTTCTATAAAGAACTCGAAATATTAGCCAAAGCTAAAAACTATATCGATGTGCCCGCATTAATGCGTA
CCTACGGTATCAACAGCGGCAAAATGTGGTTGCAATTGCGTGACGATATGCCATCTTCGATTGCCCAGCAGGACGGTAAC
GCTTAA

Upstream 100 bases:

>100_bases
CGGTGATTTTAAGGTGAGCCTCAGTCAATGGTTTCCATTTTTTACCGCTCTGGTATGATCAGTGACCATTATAAAGCACA
ACAACTGGAAAAGTGGGCTG

Downstream 100 bases:

>100_bases
GTTTCGATTCTGAAGTGTAAAAGTGGTCAGTGGCCTGTTTTAAGACTGGTTAAATAAAAAGCCGTTTCATTGAGAAACGG
CTTTTTGCTTTTTAATTCAA

Product: fatty acid metabolism regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MIINAKGPASFAEKYIVRSIWENKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLKIQHGKPTRVNNFWETSGL
NILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRNSPDTAVEVLGQIHQLEDTAESFAEYDYLLHHTLAFSSGNPL
YVLILNGFKGLYSRVGRYYFSSPEARQLALNFYKELEILAKAKNYIDVPALMRTYGINSGKMWLQLRDDMPSSIAQQDGN
A

Sequences:

>Translated_241_residues
MIINAKGPASFAEKYIVRSIWENKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLKIQHGKPTRVNNFWETSGL
NILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRNSPDTAVEVLGQIHQLEDTAESFAEYDYLLHHTLAFSSGNPL
YVLILNGFKGLYSRVGRYYFSSPEARQLALNFYKELEILAKAKNYIDVPALMRTYGINSGKMWLQLRDDMPSSIAQQDGN
A
>Mature_241_residues
MIINAKGPASFAEKYIVRSIWENKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLKIQHGKPTRVNNFWETSGL
NILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRNSPDTAVEVLGQIHQLEDTAESFAEYDYLLHHTLAFSSGNPL
YVLILNGFKGLYSRVGRYYFSSPEARQLALNFYKELEILAKAKNYIDVPALMRTYGINSGKMWLQLRDDMPSSIAQQDGN
A

Specific function: Multifunctional regulator of fatty acid metabolism

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1787436, Length=237, Percent_Identity=61.1814345991561, Blast_Score=307, Evalue=5e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FADR_SHESA (A0KVP9)

Other databases:

- EMBL:   CP000469
- RefSeq:   YP_869274.1
- ProteinModelPortal:   A0KVP9
- SMR:   A0KVP9
- STRING:   A0KVP9
- GeneID:   4476090
- GenomeReviews:   CP000469_GR
- KEGG:   shn:Shewana3_1635
- NMPDR:   fig|94122.5.peg.1717
- eggNOG:   COG2186
- HOGENOM:   HBG296777
- OMA:   IVRSIWE
- PhylomeDB:   A0KVP9
- ProtClustDB:   PRK04984
- BioCyc:   SSP94122:SHEWANA3_1635-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00696
- InterPro:   IPR014178
- InterPro:   IPR008920
- InterPro:   IPR000524
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00035
- SMART:   SM00345
- TIGRFAMs:   TIGR02812

Pfam domain/function: PF07840 FadR_C; PF00392 GntR; SSF48008 FadR_C

EC number: NA

Molecular weight: Translated: 27182; Mature: 27182

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIINAKGPASFAEKYIVRSIWENKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGW
CEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
LKIQHGKPTRVNNFWETSGLNILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRNS
EEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHEEEEHHHCCC
PDTAVEVLGQIHQLEDTAESFAEYDYLLHHTLAFSSGNPLYVLILNGFKGLYSRVGRYYF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHC
SSPEARQLALNFYKELEILAKAKNYIDVPALMRTYGINSGKMWLQLRDDMPSSIAQQDGN
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHCCCC
A
C
>Mature Secondary Structure
MIINAKGPASFAEKYIVRSIWENKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGW
CEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
LKIQHGKPTRVNNFWETSGLNILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRNS
EEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHEEEEHHHCCC
PDTAVEVLGQIHQLEDTAESFAEYDYLLHHTLAFSSGNPLYVLILNGFKGLYSRVGRYYF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHC
SSPEARQLALNFYKELEILAKAKNYIDVPALMRTYGINSGKMWLQLRDDMPSSIAQQDGN
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA; DNA [C]

Specific reaction: Activates transcription of at least two genes required for unsaturated fatty acid biosynthesis; activates the iclR gene encoding the transcription regulator of the aceBAKoperon which in turn encodes the glyoxylate shunt enzymes Protein + DNA = Protein-DN

General reaction: NA

Inhibitor: Fatty acyl CoA compounds [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA