Click here to switch to the map view.

The map label for this gene is grxD [H]

Identifier: 117920087

GI number: 117920087

Start: 1931565

End: 1931897

Strand: Direct

Name: grxD [H]

Synonym: Shewana3_1640

Alternate gene names: 117920087

Gene position: 1931565-1931897 (Clockwise)

Preceding gene: 117920082

Following gene: 117920089

Centisome position: 38.85

GC content: 41.74

Gene sequence:

>333_bases
ATGGAAACAGTAGAGAAAATTAAACAGCAGATCGCTGAAAACCCAATCATCGTATACATGAAGGGTTCTCCTAAATTACC
AAGCTGTGGTTTTTCATCTCAGGTAGCACAAATCATGATCAACTGCGGTGAGCAGTTTGCATTTGTGGATATTCTCCAGC
ACCCAGATATCCGTGCTGAATTACCTAAGTATGCAAACTGGCCAACTTTCCCACAATTGTGGATTGAAGGCGAGCTGATT
GGTGGTTGTGATATCGTGGTTGATATGTACCAAAAAGGCGAATTACAGCCGTTAATCAAAGCGACTGCTGATAAATACAA
AACCGCAGAGTAA

Upstream 100 bases:

>100_bases
AATTGTAGGGCATAACCTTACAAACTGTGGGATTTTGTTCTGTGCCTAGCTGTCGTACAATAGCAGCATTGAGTCAATGT
CATCGTACTTAGGAATTAAA

Downstream 100 bases:

>100_bases
TCACGCGCAAAAGTGATGAAAGAATAATAAAAAAGCCGTTAAGTGAATAACTTAGCGGCTTTTTTGTTGCCTGCTCCTAA
CATAAGGATTAGGCGATAAG

Product: glutaredoxin-like protein

Products: NA

Alternate protein names: Grx4; Monothiol glutaredoxin [H]

Number of amino acids: Translated: 110; Mature: 110

Protein sequence:

>110_residues
METVEKIKQQIAENPIIVYMKGSPKLPSCGFSSQVAQIMINCGEQFAFVDILQHPDIRAELPKYANWPTFPQLWIEGELI
GGCDIVVDMYQKGELQPLIKATADKYKTAE

Sequences:

>Translated_110_residues
METVEKIKQQIAENPIIVYMKGSPKLPSCGFSSQVAQIMINCGEQFAFVDILQHPDIRAELPKYANWPTFPQLWIEGELI
GGCDIVVDMYQKGELQPLIKATADKYKTAE
>Mature_110_residues
METVEKIKQQIAENPIIVYMKGSPKLPSCGFSSQVAQIMINCGEQFAFVDILQHPDIRAELPKYANWPTFPQLWIEGELI
GGCDIVVDMYQKGELQPLIKATADKYKTAE

Specific function: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters [H]

COG id: COG0278

COG function: function code O; Glutaredoxin-related protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI95113651, Length=97, Percent_Identity=38.1443298969072, Blast_Score=92, Evalue=8e-20,
Organism=Homo sapiens, GI42516576, Length=92, Percent_Identity=39.1304347826087, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1787943, Length=108, Percent_Identity=75.9259259259259, Blast_Score=186, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17556042, Length=107, Percent_Identity=30.8411214953271, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71988153, Length=82, Percent_Identity=35.3658536585366, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71988159, Length=75, Percent_Identity=41.3333333333333, Blast_Score=76, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6325198, Length=102, Percent_Identity=36.2745098039216, Blast_Score=89, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321022, Length=72, Percent_Identity=48.6111111111111, Blast_Score=86, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6320303, Length=81, Percent_Identity=43.2098765432099, Blast_Score=86, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24642023, Length=85, Percent_Identity=45.8823529411765, Blast_Score=97, Evalue=1e-21,
Organism=Drosophila melanogaster, GI19921242, Length=97, Percent_Identity=37.1134020618557, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002109
- InterPro:   IPR014434
- InterPro:   IPR004480
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 12389; Mature: 12389

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METVEKIKQQIAENPIIVYMKGSPKLPSCGFSSQVAQIMINCGEQFAFVDILQHPDIRAE
CCHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
LPKYANWPTFPQLWIEGELIGGCDIVVDMYQKGELQPLIKATADKYKTAE
CCCCCCCCCCCCEEECCEEECCHHHHHHHHHCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
METVEKIKQQIAENPIIVYMKGSPKLPSCGFSSQVAQIMINCGEQFAFVDILQHPDIRAE
CCHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
LPKYANWPTFPQLWIEGELIGGCDIVVDMYQKGELQPLIKATADKYKTAE
CCCCCCCCCCCCEEECCEEECCHHHHHHHHHCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]