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The map label for this gene is uvrC [H]

Identifier: 117920057

GI number: 117920057

Start: 1889881

End: 1891710

Strand: Direct

Name: uvrC [H]

Synonym: Shewana3_1609

Alternate gene names: 117920057

Gene position: 1889881-1891710 (Clockwise)

Preceding gene: 117920056

Following gene: 117920058

Centisome position: 38.01

GC content: 49.62

Gene sequence:

>1830_bases
ATGTCGACAGGTTTTAACGCCCAGAGTTTTTTACGCATGGTCTCATCCTCTGCTGGGGTTTATCGCATGTATGACGTCAA
AGGTGACGTCATCTATGTGGGTAAAGCCAAAGATCTTAAGAAGCGCTTATCCTCCTATTTCCGTAAAAACCTTGGGAATG
TGAAAACCCAAGCGCTGGTGTCCCATATCCATCATATCGATGTGACGCTGACCCACAGCGAGACCGATGCGCTGCTGCTT
GAGAATGACTATATCAAGCAGTACATGCCCAAATACAATGTGTTACTGCGGGACGATAAGTCATACCCTTATATTTTCTT
GAGCCAACACGAGCATCCACGCCTCGCATACCATCGCGGACCGCAGCGGGAAAAGGGCTATTACTTTGGGCCTTATCCTA
ATGGCGGCGCGGTGCGTGAAAGTTTGCACTTGATGCAAAAGCTGTTTCCTATCCGCCAGTGTGATGATCTCTATTATAAA
TCCCGCACTCGTCCCTGCCTGCAGTACCAGTTATCCCGTTGCAGTGCACCTTGCGTCGGTAAGGTCAGTAATGCGGAGTA
TGACGAGCAGGTTAAACTCGCCAGTTTGTTCCTTAAGGGAAAAGATAAGCAAGTCATCAGTGAACTTGTGGCAAAGATGG
AAGAGGCCGCCGGGCAGCAAGCCTATGAGCAAGCTGCGCGCTTTCGCGATCAAATTATGGCGCTACGCCGGGTGGCCGAG
CAGCAAGAAGTCTCAGGTAATACTGGGGATATGGATGTTATCGGTGTGCACTACGCTTCGGGCATCGCGTGTTTTCACCT
ATTATTTATCCGCGAAGGTAAAATTTTTGGTAGCCGCAGCTATTATCCAACGGTGCCCGCGCAAACAGATATCGAAGAAG
TCTTACGTTCCTTCCTATTACAGTTTTATTTAAATGCCGATATTCAACGCACAATTCCTAAGGAAGTGGTGATAAGCCAT
CACTTTGAAGAATTGCATGAGTTAGAAGCGGCCGTCTCTGAGGCGTTAAATAAAAAGTTCAGCATCAAAACCAATGTGCG
CGCCGACAGGGCAAGCTTTTTGCGCCTCGCGCTGACCAATGCCACCAATGCGGTGATGACGCGTTTGTCCCATAAAAACA
CCGTTGAACAGCGTTTTGTCTTGCTGGAGGAAATCCTCGAGCTTAATGCGCCAATTCAGCGGATGGAGTGTTTCGATATC
AGCCATACCATGGGGGAGAGCACGGTAGCCTCCTGCGTGGTGTTTAACCGCGAGGGGCCCCATAAGGCCGAATACCGCCG
CTACAATATTGAAGGGATTACACCTGGCGATGATTATGCTGCGATGAAACAAGCTATTAGTCGCCGATTTGATAAAATCG
ATGCCAGCGGCAAAATTCCTGACATCTTATTTATCGACGGTGGCTTGGGCCAGCTGCGTATCGCCCAGCAAATAGTGGAT
GAGAAATTCGTCAATTTAGATAAAGCGCCGCAACTGATTGGGGTGGCAAAGGGGGAGAGCCGTAAACCCGGGCTTGAAAC
CTTAATCTTCGGCGACACAGAAACGAGCTTTTCCCTTGAGGATGACTCGCCAGCGCTGCACCTTATTCAACATATTCGCG
ATGAGTCCCACCGCTTTGCGATTACAGGCCATCGCAATCGTCGCCAGAAAACCCGTAACACCTCGACGCTCGAGTCGATT
CCTGGCATTGGTCCTAAGCGGCGCAAGGCGTTATTGCAACATCTTGGTGGTTTACAGGAAGTGAAGGGCGCGAGTGTGGC
CGAGTTAGCGAAAGTACCCGGTATTAGCATAGAAATGGCACAAACCATTCATGATGCATTGCGAGGGTGA

Upstream 100 bases:

>100_bases
GTGTCAATGAATCTAGCATTAATTAAGTGTTAGCAGTGAGTGTGAAGACGATTTATCAAGTTGTGTTGAAGACCGTGAGT
AAAAGAGTGGGTTTATAACG

Downstream 100 bases:

>100_bases
TAAATTTAAGGCAAGATTGGCGCTGCTTTTGACTAACTGGTTTGATCATGCCGTTTAACTTACCTATAGCATTAACCCTT
TTTAGGCTTTTTTTACTGCC

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 609; Mature: 608

Protein sequence:

>609_residues
MSTGFNAQSFLRMVSSSAGVYRMYDVKGDVIYVGKAKDLKKRLSSYFRKNLGNVKTQALVSHIHHIDVTLTHSETDALLL
ENDYIKQYMPKYNVLLRDDKSYPYIFLSQHEHPRLAYHRGPQREKGYYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYK
SRTRPCLQYQLSRCSAPCVGKVSNAEYDEQVKLASLFLKGKDKQVISELVAKMEEAAGQQAYEQAARFRDQIMALRRVAE
QQEVSGNTGDMDVIGVHYASGIACFHLLFIREGKIFGSRSYYPTVPAQTDIEEVLRSFLLQFYLNADIQRTIPKEVVISH
HFEELHELEAAVSEALNKKFSIKTNVRADRASFLRLALTNATNAVMTRLSHKNTVEQRFVLLEEILELNAPIQRMECFDI
SHTMGESTVASCVVFNREGPHKAEYRRYNIEGITPGDDYAAMKQAISRRFDKIDASGKIPDILFIDGGLGQLRIAQQIVD
EKFVNLDKAPQLIGVAKGESRKPGLETLIFGDTETSFSLEDDSPALHLIQHIRDESHRFAITGHRNRRQKTRNTSTLESI
PGIGPKRRKALLQHLGGLQEVKGASVAELAKVPGISIEMAQTIHDALRG

Sequences:

>Translated_609_residues
MSTGFNAQSFLRMVSSSAGVYRMYDVKGDVIYVGKAKDLKKRLSSYFRKNLGNVKTQALVSHIHHIDVTLTHSETDALLL
ENDYIKQYMPKYNVLLRDDKSYPYIFLSQHEHPRLAYHRGPQREKGYYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYK
SRTRPCLQYQLSRCSAPCVGKVSNAEYDEQVKLASLFLKGKDKQVISELVAKMEEAAGQQAYEQAARFRDQIMALRRVAE
QQEVSGNTGDMDVIGVHYASGIACFHLLFIREGKIFGSRSYYPTVPAQTDIEEVLRSFLLQFYLNADIQRTIPKEVVISH
HFEELHELEAAVSEALNKKFSIKTNVRADRASFLRLALTNATNAVMTRLSHKNTVEQRFVLLEEILELNAPIQRMECFDI
SHTMGESTVASCVVFNREGPHKAEYRRYNIEGITPGDDYAAMKQAISRRFDKIDASGKIPDILFIDGGLGQLRIAQQIVD
EKFVNLDKAPQLIGVAKGESRKPGLETLIFGDTETSFSLEDDSPALHLIQHIRDESHRFAITGHRNRRQKTRNTSTLESI
PGIGPKRRKALLQHLGGLQEVKGASVAELAKVPGISIEMAQTIHDALRG
>Mature_608_residues
STGFNAQSFLRMVSSSAGVYRMYDVKGDVIYVGKAKDLKKRLSSYFRKNLGNVKTQALVSHIHHIDVTLTHSETDALLLE
NDYIKQYMPKYNVLLRDDKSYPYIFLSQHEHPRLAYHRGPQREKGYYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYKS
RTRPCLQYQLSRCSAPCVGKVSNAEYDEQVKLASLFLKGKDKQVISELVAKMEEAAGQQAYEQAARFRDQIMALRRVAEQ
QEVSGNTGDMDVIGVHYASGIACFHLLFIREGKIFGSRSYYPTVPAQTDIEEVLRSFLLQFYLNADIQRTIPKEVVISHH
FEELHELEAAVSEALNKKFSIKTNVRADRASFLRLALTNATNAVMTRLSHKNTVEQRFVLLEEILELNAPIQRMECFDIS
HTMGESTVASCVVFNREGPHKAEYRRYNIEGITPGDDYAAMKQAISRRFDKIDASGKIPDILFIDGGLGQLRIAQQIVDE
KFVNLDKAPQLIGVAKGESRKPGLETLIFGDTETSFSLEDDSPALHLIQHIRDESHRFAITGHRNRRQKTRNTSTLESIP
GIGPKRRKALLQHLGGLQEVKGASVAELAKVPGISIEMAQTIHDALRG

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=610, Percent_Identity=57.7049180327869, Blast_Score=729, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 68872; Mature: 68740

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTGFNAQSFLRMVSSSAGVYRMYDVKGDVIYVGKAKDLKKRLSSYFRKNLGNVKTQALV
CCCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHCCHHHHHHH
SHIHHIDVTLTHSETDALLLENDYIKQYMPKYNVLLRDDKSYPYIFLSQHEHPRLAYHRG
HHHHHEEEEEEECCCCEEEEECHHHHHHCCCCCEEEECCCCCCEEEEECCCCCCHHHCCC
PQREKGYYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYKSRTRPCLQYQLSRCSAPCVG
CCCCCCEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
KVSNAEYDEQVKLASLFLKGKDKQVISELVAKMEEAAGQQAYEQAARFRDQIMALRRVAE
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQEVSGNTGDMDVIGVHYASGIACFHLLFIREGKIFGSRSYYPTVPAQTDIEEVLRSFLL
HHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHHHH
QFYLNADIQRTIPKEVVISHHFEELHELEAAVSEALNKKFSIKTNVRADRASFLRLALTN
HHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHH
ATNAVMTRLSHKNTVEQRFVLLEEILELNAPIQRMECFDISHTMGESTVASCVVFNREGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHEEEECCCCC
HKAEYRRYNIEGITPGDDYAAMKQAISRRFDKIDASGKIPDILFIDGGLGQLRIAQQIVD
CCCHHEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHH
EKFVNLDKAPQLIGVAKGESRKPGLETLIFGDTETSFSLEDDSPALHLIQHIRDESHRFA
HHHHCCCCCCCEEEECCCCCCCCCCCEEEECCCCCCEEECCCCHHHHHHHHHHCCCCEEE
ITGHRNRRQKTRNTSTLESIPGIGPKRRKALLQHLGGLQEVKGASVAELAKVPGISIEMA
EECCCHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHCCCCCHHHH
QTIHDALRG
HHHHHHHCC
>Mature Secondary Structure 
STGFNAQSFLRMVSSSAGVYRMYDVKGDVIYVGKAKDLKKRLSSYFRKNLGNVKTQALV
CCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHCCHHHHHHH
SHIHHIDVTLTHSETDALLLENDYIKQYMPKYNVLLRDDKSYPYIFLSQHEHPRLAYHRG
HHHHHEEEEEEECCCCEEEEECHHHHHHCCCCCEEEECCCCCCEEEEECCCCCCHHHCCC
PQREKGYYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYKSRTRPCLQYQLSRCSAPCVG
CCCCCCEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
KVSNAEYDEQVKLASLFLKGKDKQVISELVAKMEEAAGQQAYEQAARFRDQIMALRRVAE
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQEVSGNTGDMDVIGVHYASGIACFHLLFIREGKIFGSRSYYPTVPAQTDIEEVLRSFLL
HHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHHHH
QFYLNADIQRTIPKEVVISHHFEELHELEAAVSEALNKKFSIKTNVRADRASFLRLALTN
HHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHH
ATNAVMTRLSHKNTVEQRFVLLEEILELNAPIQRMECFDISHTMGESTVASCVVFNREGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHEEEECCCCC
HKAEYRRYNIEGITPGDDYAAMKQAISRRFDKIDASGKIPDILFIDGGLGQLRIAQQIVD
CCCHHEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHH
EKFVNLDKAPQLIGVAKGESRKPGLETLIFGDTETSFSLEDDSPALHLIQHIRDESHRFA
HHHHCCCCCCCEEEECCCCCCCCCCCEEEECCCCCCEEECCCCHHHHHHHHHHCCCCEEE
ITGHRNRRQKTRNTSTLESIPGIGPKRRKALLQHLGGLQEVKGASVAELAKVPGISIEMA
EECCCHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHCCCCCHHHH
QTIHDALRG
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA