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The map label for this gene is uvrY [H]

Identifier: 117920056

GI number: 117920056

Start: 1889127

End: 1889771

Strand: Direct

Name: uvrY [H]

Synonym: Shewana3_1608

Alternate gene names: 117920056

Gene position: 1889127-1889771 (Clockwise)

Preceding gene: 117920053

Following gene: 117920057

Centisome position: 37.99

GC content: 47.6

Gene sequence:

>645_bases
TTGATATCGATATATTTAGTTGACGACCATGAGCTTGTAAGAACTGGGATCCGCCGCATCTTAGAAGATGAACGTGGGAT
CAAAGTCGTGGGAGAAGCGCCTGATGGCGAAACCGCGGTACAGTGGGCGAGACAAAATGAAGCCGATGTCATCTTAATGG
ACATGAATATGCCAGGGATGGGCGGGCTTGAAGCCACGCGTAAGATTTTACGTTATCAGCCCCATGCCAAGATTATTGTG
TTAACTGTGCATACTGAAGATCCTTTCCCCAGCAAAGTGATGCAGGCGGGCGCGTCTGGTTATTTAACCAAAGGGGCGAC
ACCTCCCGAAGTACTGCAAGCGATACGTCAGGTTTCCCGTGGTCAGCGTTATTTATCTCCAGAAATTGCCCAACAAATGG
CATTGAGCCAATTCAATCCCGCCGATGAGAATCCGTTTAAAGCCTTGTCCGAGCGTGAGCTGCAAATTATGTTGATGATC
ACCAATGGTGAAAAGGTCAATGATATTTCTGAGCAGCTCAACTTAAGCCCCAAAACCGTTAACAGCTACCGTTATCGCTT
ATTTGCGAAGCTTGGGATCAGTGGTGATGTGGAGCTGACCCGTTTAGCGATCCGTTATAAAATGTTAGACGCTGGCCATT
TCTAG

Upstream 100 bases:

>100_bases
CCATTGTTGGGCTAAATTACCCTGATAACCTATATTCCGGTTGCGGTATTCTGATTTGACTACACTGTGTTAGTCGACAT
TGGTTAAAGGTGGATAAAAG

Downstream 100 bases:

>100_bases
TGGCCGCTTGTGTCAATGAATCTAGCATTAATTAAGTGTTAGCAGTGAGTGTGAAGACGATTTATCAAGTTGTGTTGAAG
ACCGTGAGTAAAAGAGTGGG

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MISIYLVDDHELVRTGIRRILEDERGIKVVGEAPDGETAVQWARQNEADVILMDMNMPGMGGLEATRKILRYQPHAKIIV
LTVHTEDPFPSKVMQAGASGYLTKGATPPEVLQAIRQVSRGQRYLSPEIAQQMALSQFNPADENPFKALSERELQIMLMI
TNGEKVNDISEQLNLSPKTVNSYRYRLFAKLGISGDVELTRLAIRYKMLDAGHF

Sequences:

>Translated_214_residues
MISIYLVDDHELVRTGIRRILEDERGIKVVGEAPDGETAVQWARQNEADVILMDMNMPGMGGLEATRKILRYQPHAKIIV
LTVHTEDPFPSKVMQAGASGYLTKGATPPEVLQAIRQVSRGQRYLSPEIAQQMALSQFNPADENPFKALSERELQIMLMI
TNGEKVNDISEQLNLSPKTVNSYRYRLFAKLGISGDVELTRLAIRYKMLDAGHF
>Mature_214_residues
MISIYLVDDHELVRTGIRRILEDERGIKVVGEAPDGETAVQWARQNEADVILMDMNMPGMGGLEATRKILRYQPHAKIIV
LTVHTEDPFPSKVMQAGASGYLTKGATPPEVLQAIRQVSRGQRYLSPEIAQQMALSQFNPADENPFKALSERELQIMLMI
TNGEKVNDISEQLNLSPKTVNSYRYRLFAKLGISGDVELTRLAIRYKMLDAGHF

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop. Mediates the

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=212, Percent_Identity=71.2264150943396, Blast_Score=313, Evalue=4e-87,
Organism=Escherichia coli, GI1788521, Length=204, Percent_Identity=36.2745098039216, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1790102, Length=202, Percent_Identity=35.6435643564356, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786747, Length=207, Percent_Identity=25.1207729468599, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788712, Length=206, Percent_Identity=27.1844660194175, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1787473, Length=183, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1788546, Length=203, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24026; Mature: 24026

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISIYLVDDHELVRTGIRRILEDERGIKVVGEAPDGETAVQWARQNEADVILMDMNMPGM
CEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCC
GGLEATRKILRYQPHAKIIVLTVHTEDPFPSKVMQAGASGYLTKGATPPEVLQAIRQVSR
CCHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHC
GQRYLSPEIAQQMALSQFNPADENPFKALSERELQIMLMITNGEKVNDISEQLNLSPKTV
CCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCCCCHH
NSYRYRLFAKLGISGDVELTRLAIRYKMLDAGHF
HHHHEEEEEEECCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MISIYLVDDHELVRTGIRRILEDERGIKVVGEAPDGETAVQWARQNEADVILMDMNMPGM
CEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCC
GGLEATRKILRYQPHAKIIVLTVHTEDPFPSKVMQAGASGYLTKGATPPEVLQAIRQVSR
CCHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHC
GQRYLSPEIAQQMALSQFNPADENPFKALSERELQIMLMITNGEKVNDISEQLNLSPKTV
CCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCCCCHH
NSYRYRLFAKLGISGDVELTRLAIRYKMLDAGHF
HHHHEEEEEEECCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]