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The map label for this gene is ptrB [H]

Identifier: 117918593

GI number: 117918593

Start: 153400

End: 155535

Strand: Direct

Name: ptrB [H]

Synonym: Shewana3_0135

Alternate gene names: 117918593

Gene position: 153400-155535 (Clockwise)

Preceding gene: 117918590

Following gene: 117918594

Centisome position: 3.09

GC content: 50.47

Gene sequence:

>2136_bases
ATGCGCACTCTGCTGCTTACTTTAGGTCTCGCTATGCTATTACCCGGTTGCTCCACTCCAAAAGGGCTAGTTTCTGCGCC
CGTTGCGGAAAAAATTCCCCATGTGATGACCTTGCACGGGGTCACGCGCACCGACGATTACTACTGGATGCGCGACGATA
AACGCCAAGATCCTAAGGTGTTGGCGCATCTGAATGCCGAAAACCGTTATACCCAAGCCTACTTTAAACCGCTTAAGTCA
TTGCAGGATGGGCTTTTTAACGAACTGACTGGGCGCCTCGTTGCCGATGAGTCGAGCGTGCCTTACCAATGGCACCAGCA
CAGTTATTATCGCCGCTACCAAGAGGGCGGCGAATATCCGCTGATCGCTCGCAAAGGCAGTGACGGGATTGAGCAAATGA
TGCTGGACGTGAATGAGCGCGCCAAGGGCCATGAGTTTTATGGTTTAGGTGGCGTCAGCGTCAGCCCAGATGAAACCATG
CTGGCCTTCGGTGAAGATGTGCTAAGCCGCCGCGTGTATCACATCTATTTTAAAGATATTGAGTCCGGCGCCATGATCAC
CGATGTGCTTGAAAACACAGAGGGTCGTATCGTTTGGGGCAATGATAATCGCCATGTGTTTTATATCGCTAAAGATCTGC
AAACCCTGCTCGGCTACCGTGTATATCGCCACGAACTCGGCACGCCACAATCGAGCGATGTGTTGGTGTATGAGGAGCAA
GATGATGCTTATTACATCTCCCTCGGCAAGAGTTTAGACGAGTCGCAAATTGTGCTGTTCCACGAGAGCACCACCACTAG
CGAAGTGTCGGTACTGGATGCTAACGATCCCTTAAGCCTGTTCAAACCTGTGCTGGCGCGGGAAGAAGGCCATGAATACA
GCGTCTCTAAGCTGGGCGATAGCTATTACATTCTCACCAACTGGCAGGCGACAAACTTCCGTTTGATGAAAGTGGCGATT
AAGGATGCCGCCGATAAATCCAAATGGCAGGAAGTGGTTGCCCATAATCCCAATGCGCGTATCGAAGACGAGCTGGTGCT
GAAGGATTATTTGATTATTCAAACCCGCGAGAATGGCCTGACGCGGATTAAAGTGATGCCATTCAATGGTCAAAAGCCCT
TTGAGCTGAGTTTTGACGAGCCCGCCTATGTGCTCGGTTTAGATGTGAACGCCCAGCAAGATAGCGATAAGTTACGGATT
TTCTACTCGAGCCTGACCACGCCCGAGGCGATTTATGAGTACCACTTAAGCAATCCCGATAGACGCGATCTACTCAAGCA
GGAACAAGTGCTCGGCGGCTTCGATGCCAGCCAATATCGCGCCGAACGTTTATTTGTTACCGCCCGCGATGGCGCTAAGG
TGCCAGTGTCCTTGGTGTATCGTAAGGATAAGTTCAAGAAAGATGGCACTAACCCTCTGTATCAATATGGTTATGGTTCA
TACGGTTACACTGTAGAACCTGATTTTTCGTCGTCGGTGGTCAGTCTGCTCGACCGTGGCTTTGTGTATGCCATCGCCCA
TGTGCGCGGCAGCGAAATGCTCGGCCGCCCTTGGTACGATGCGGGTAAGTTGCTGAATAAAAAGAATACCTTTAATGACT
TTATCGATGTCACCACTGCCTTAACCGAGCAAGGTTATGGCGATAAAAATAAAGTGGTGGCCTCGGGTGGCAGTGCCGGC
GGGCTGTTAATGGGCGCGATTGCCAATATGGCGCCTGAAAAGTACTTTGCTATCGCGGCGCATGTGCCCTTTGTGGATGT
GGTGACGACCATGCTCGATGAGTCGATTCCGCTCACCACCAACGAGTACGATGAATGGGGTAATCCAAACGAGAAGACCT
ATTTCGACTATATGCTCAGCTACTCACCCTATGACAATGTTGCCGACCATGAATACCCACACCTGTTAGTCACCACAGGT
TTGCATGATTCACAGGTGCAGTATTTCGAGCCTGCGAAATGGGTAGCAAAACTGCGTGAAGTGCAAAATAAATGGTACAA
ACTGGACGATAAGGTGTTGTTATTCGAAGTTAATATGGATGCTGGCCACGGTGGCAAGAGTGGCCGTTACCGCCAGTATC
AAGACACAGCGCAGGAATATGCCTTCTTCTTAAGCCTGCTCGGCATGACTAAGTAG

Upstream 100 bases:

>100_bases
CGCAACAAGCGCTAGCTTGGGTATATCATATCCGACACATCAACTTATTGGCTTGCCGTCGTGCCCCTCGATGGTGTTTG
AACGTCACAAGGACGTATAA

Downstream 100 bases:

>100_bases
GCGCCAACGGGTGACCGATTTAGTGATTGAAGCTGCTAATTCAACTCCCTCGGCTAGCCCCAAAAAAGGGGCTAGCCAAA
CTCAAGCTGCTAACCAAGCT

Product: oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 711; Mature: 711

Protein sequence:

>711_residues
MRTLLLTLGLAMLLPGCSTPKGLVSAPVAEKIPHVMTLHGVTRTDDYYWMRDDKRQDPKVLAHLNAENRYTQAYFKPLKS
LQDGLFNELTGRLVADESSVPYQWHQHSYYRRYQEGGEYPLIARKGSDGIEQMMLDVNERAKGHEFYGLGGVSVSPDETM
LAFGEDVLSRRVYHIYFKDIESGAMITDVLENTEGRIVWGNDNRHVFYIAKDLQTLLGYRVYRHELGTPQSSDVLVYEEQ
DDAYYISLGKSLDESQIVLFHESTTTSEVSVLDANDPLSLFKPVLAREEGHEYSVSKLGDSYYILTNWQATNFRLMKVAI
KDAADKSKWQEVVAHNPNARIEDELVLKDYLIIQTRENGLTRIKVMPFNGQKPFELSFDEPAYVLGLDVNAQQDSDKLRI
FYSSLTTPEAIYEYHLSNPDRRDLLKQEQVLGGFDASQYRAERLFVTARDGAKVPVSLVYRKDKFKKDGTNPLYQYGYGS
YGYTVEPDFSSSVVSLLDRGFVYAIAHVRGSEMLGRPWYDAGKLLNKKNTFNDFIDVTTALTEQGYGDKNKVVASGGSAG
GLLMGAIANMAPEKYFAIAAHVPFVDVVTTMLDESIPLTTNEYDEWGNPNEKTYFDYMLSYSPYDNVADHEYPHLLVTTG
LHDSQVQYFEPAKWVAKLREVQNKWYKLDDKVLLFEVNMDAGHGGKSGRYRQYQDTAQEYAFFLSLLGMTK

Sequences:

>Translated_711_residues
MRTLLLTLGLAMLLPGCSTPKGLVSAPVAEKIPHVMTLHGVTRTDDYYWMRDDKRQDPKVLAHLNAENRYTQAYFKPLKS
LQDGLFNELTGRLVADESSVPYQWHQHSYYRRYQEGGEYPLIARKGSDGIEQMMLDVNERAKGHEFYGLGGVSVSPDETM
LAFGEDVLSRRVYHIYFKDIESGAMITDVLENTEGRIVWGNDNRHVFYIAKDLQTLLGYRVYRHELGTPQSSDVLVYEEQ
DDAYYISLGKSLDESQIVLFHESTTTSEVSVLDANDPLSLFKPVLAREEGHEYSVSKLGDSYYILTNWQATNFRLMKVAI
KDAADKSKWQEVVAHNPNARIEDELVLKDYLIIQTRENGLTRIKVMPFNGQKPFELSFDEPAYVLGLDVNAQQDSDKLRI
FYSSLTTPEAIYEYHLSNPDRRDLLKQEQVLGGFDASQYRAERLFVTARDGAKVPVSLVYRKDKFKKDGTNPLYQYGYGS
YGYTVEPDFSSSVVSLLDRGFVYAIAHVRGSEMLGRPWYDAGKLLNKKNTFNDFIDVTTALTEQGYGDKNKVVASGGSAG
GLLMGAIANMAPEKYFAIAAHVPFVDVVTTMLDESIPLTTNEYDEWGNPNEKTYFDYMLSYSPYDNVADHEYPHLLVTTG
LHDSQVQYFEPAKWVAKLREVQNKWYKLDDKVLLFEVNMDAGHGGKSGRYRQYQDTAQEYAFFLSLLGMTK
>Mature_711_residues
MRTLLLTLGLAMLLPGCSTPKGLVSAPVAEKIPHVMTLHGVTRTDDYYWMRDDKRQDPKVLAHLNAENRYTQAYFKPLKS
LQDGLFNELTGRLVADESSVPYQWHQHSYYRRYQEGGEYPLIARKGSDGIEQMMLDVNERAKGHEFYGLGGVSVSPDETM
LAFGEDVLSRRVYHIYFKDIESGAMITDVLENTEGRIVWGNDNRHVFYIAKDLQTLLGYRVYRHELGTPQSSDVLVYEEQ
DDAYYISLGKSLDESQIVLFHESTTTSEVSVLDANDPLSLFKPVLAREEGHEYSVSKLGDSYYILTNWQATNFRLMKVAI
KDAADKSKWQEVVAHNPNARIEDELVLKDYLIIQTRENGLTRIKVMPFNGQKPFELSFDEPAYVLGLDVNAQQDSDKLRI
FYSSLTTPEAIYEYHLSNPDRRDLLKQEQVLGGFDASQYRAERLFVTARDGAKVPVSLVYRKDKFKKDGTNPLYQYGYGS
YGYTVEPDFSSSVVSLLDRGFVYAIAHVRGSEMLGRPWYDAGKLLNKKNTFNDFIDVTTALTEQGYGDKNKVVASGGSAG
GLLMGAIANMAPEKYFAIAAHVPFVDVVTTMLDESIPLTTNEYDEWGNPNEKTYFDYMLSYSPYDNVADHEYPHLLVTTG
LHDSQVQYFEPAKWVAKLREVQNKWYKLDDKVLLFEVNMDAGHGGKSGRYRQYQDTAQEYAFFLSLLGMTK

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=711, Percent_Identity=24.6132208157525, Blast_Score=200, Evalue=4e-51,
Organism=Homo sapiens, GI284172438, Length=451, Percent_Identity=27.9379157427938, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI284172431, Length=451, Percent_Identity=27.9379157427938, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI284172420, Length=451, Percent_Identity=27.9379157427938, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI284172413, Length=451, Percent_Identity=27.9379157427938, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI70778815, Length=451, Percent_Identity=27.9379157427938, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI108860686, Length=285, Percent_Identity=29.1228070175439, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI108860692, Length=215, Percent_Identity=33.0232558139535, Blast_Score=119, Evalue=1e-26,
Organism=Escherichia coli, GI1788150, Length=684, Percent_Identity=47.3684210526316, Blast_Score=638, Evalue=0.0,
Organism=Drosophila melanogaster, GI24583414, Length=742, Percent_Identity=25.8760107816712, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI221510989, Length=697, Percent_Identity=23.6728837876614, Blast_Score=170, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 80913; Mature: 80913

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLLLTLGLAMLLPGCSTPKGLVSAPVAEKIPHVMTLHGVTRTDDYYWMRDDKRQDPKV
CCCHHHHHHHHHHCCCCCCCCCHHCCCHHHHCCCEEEECCCEECCCEEEECCCCCCCCCE
LAHLNAENRYTQAYFKPLKSLQDGLFNELTGRLVADESSVPYQWHQHSYYRRYQEGGEYP
EEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHCCCCEE
LIARKGSDGIEQMMLDVNERAKGHEFYGLGGVSVSPDETMLAFGEDVLSRRVYHIYFKDI
EEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCEEEEEEEEC
ESGAMITDVLENTEGRIVWGNDNRHVFYIAKDLQTLLGYRVYRHELGTPQSSDVLVYEEQ
CCCCHHHHHHHCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCEEEEECC
DDAYYISLGKSLDESQIVLFHESTTTSEVSVLDANDPLSLFKPVLAREEGHEYSVSKLGD
CCEEEEEECCCCCCCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHCCCCCCEEHHHCCC
SYYILTNWQATNFRLMKVAIKDAADKSKWQEVVAHNPNARIEDELVLKDYLIIQTRENGL
CEEEEEECCCCCEEEEEEEEHHHCCHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCC
TRIKVMPFNGQKPFELSFDEPAYVLGLDVNAQQDSDKLRIFYSSLTTPEAIYEYHLSNPD
EEEEEEECCCCCCEEECCCCCEEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHCCCCC
RRDLLKQEQVLGGFDASQYRAERLFVTARDGAKVPVSLVYRKDKFKKDGTNPLYQYGYGS
HHHHHHHHHHHCCCCHHHHEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHCCCCC
YGYTVEPDFSSSVVSLLDRGFVYAIAHVRGSEMLGRPWYDAGKLLNKKNTFNDFIDVTTA
CCCEECCCCCHHHHHHHHCCCEEEEEEECCCHHCCCCCHHHHHHHCCCCCHHHHHHHHHH
LTEQGYGDKNKVVASGGSAGGLLMGAIANMAPEKYFAIAAHVPFVDVVTTMLDESIPLTT
HHHCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCC
NEYDEWGNPNEKTYFDYMLSYSPYDNVADHEYPHLLVTTGLHDSQVQYFEPAKWVAKLRE
CCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCHHCCHHHHHHHHHH
VQNKWYKLDDKVLLFEVNMDAGHGGKSGRYRQYQDTAQEYAFFLSLLGMTK
HHHHHEECCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRTLLLTLGLAMLLPGCSTPKGLVSAPVAEKIPHVMTLHGVTRTDDYYWMRDDKRQDPKV
CCCHHHHHHHHHHCCCCCCCCCHHCCCHHHHCCCEEEECCCEECCCEEEECCCCCCCCCE
LAHLNAENRYTQAYFKPLKSLQDGLFNELTGRLVADESSVPYQWHQHSYYRRYQEGGEYP
EEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHCCCCEE
LIARKGSDGIEQMMLDVNERAKGHEFYGLGGVSVSPDETMLAFGEDVLSRRVYHIYFKDI
EEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCEEEEEEEEC
ESGAMITDVLENTEGRIVWGNDNRHVFYIAKDLQTLLGYRVYRHELGTPQSSDVLVYEEQ
CCCCHHHHHHHCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCEEEEECC
DDAYYISLGKSLDESQIVLFHESTTTSEVSVLDANDPLSLFKPVLAREEGHEYSVSKLGD
CCEEEEEECCCCCCCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHCCCCCCEEHHHCCC
SYYILTNWQATNFRLMKVAIKDAADKSKWQEVVAHNPNARIEDELVLKDYLIIQTRENGL
CEEEEEECCCCCEEEEEEEEHHHCCHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCC
TRIKVMPFNGQKPFELSFDEPAYVLGLDVNAQQDSDKLRIFYSSLTTPEAIYEYHLSNPD
EEEEEEECCCCCCEEECCCCCEEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHCCCCC
RRDLLKQEQVLGGFDASQYRAERLFVTARDGAKVPVSLVYRKDKFKKDGTNPLYQYGYGS
HHHHHHHHHHHCCCCHHHHEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHCCCCC
YGYTVEPDFSSSVVSLLDRGFVYAIAHVRGSEMLGRPWYDAGKLLNKKNTFNDFIDVTTA
CCCEECCCCCHHHHHHHHCCCEEEEEEECCCHHCCCCCHHHHHHHCCCCCHHHHHHHHHH
LTEQGYGDKNKVVASGGSAGGLLMGAIANMAPEKYFAIAAHVPFVDVVTTMLDESIPLTT
HHHCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCC
NEYDEWGNPNEKTYFDYMLSYSPYDNVADHEYPHLLVTTGLHDSQVQYFEPAKWVAKLRE
CCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCHHCCHHHHHHHHHH
VQNKWYKLDDKVLLFEVNMDAGHGGKSGRYRQYQDTAQEYAFFLSLLGMTK
HHHHHEECCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]