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The map label for this gene is exbB [H]

Identifier: 116689738

GI number: 116689738

Start: 1910442

End: 1911353

Strand: Reverse

Name: exbB [H]

Synonym: Bcen2424_1716

Alternate gene names: 116689738

Gene position: 1911353-1910442 (Counterclockwise)

Preceding gene: 116689739

Following gene: 116689737

Centisome position: 54.86

GC content: 69.63

Gene sequence:

>912_bases
ATGACGAAGCGTTCTCTGGCCGCGCTGGCGGCAAGCCTGTTGATGTCCGTCGCCGCAATCGACGGGCTCGTTGCACCGCA
GCTCGCTTACGCGCAAGCGAGCGGAACCGCGTCGACATCCGATGCGCCGACGCAGGCCGCGGCGCCGACGCAGGCGCCCG
CTGCCGCCGAGCCGGCCCCGCCGCCGGCGCCGGCGCCGGCTACGACCGAAGCGGTCGAGAATCCGTACGGGCTCGGGGCG
CTCTGGAAGAACGGCGACTTCGTCGCGCGCTTCGTGCTGATCCTGCTCGTGATCATGTCGATGGGCAGCTGGTACATCAT
GATCTCGAAGTTCGTCGAACAGTTGCGGGCGAACCGCCGCGCGAAACTCGCCGACGCGCAGCTCTGGAGCGCGCCGTCGC
TGGCCGAGGGCGCGAAGCTGCTCGACGAGGCGTCGCCGTTCCGCTTCATCGCCGAAACGGCGATCGAGGCGGGCGAGCAT
CACGACGAGGCGCTGCTCGAAGCCGTGGACCGCAACACATGGATCGACGTGTCCGTCGAGCGCTCGATCACGAACGTGTC
GAACCGCATGCAGGACGGGCTCGCGTTCCTCGCGACGGTCGGCTCGACCGCGCCGTTCGTCGGGCTGTTCGGCACGGTCT
GGGGGATCTATCACGCGCTGACGGCGATCGGGATCGCGGGCCAGGCGTCGATCGACAAGGTCGCGGGCCCGGTGGGCGAG
GCGCTCATCATGACGGCGATCGGCCTGGCGGTCGCGGTGCCGGCCGTACTCGGCTACAACTTCCTGGTCCGGCGCAACAA
GTCGGTGATGGAGCGGGTCCGCAACTTCGGCGCCCAGCTGCATACCGTGCTGCTGGCCGGCAGCAAGCGTCCCGCTCGCG
TGCCGTCGCCCGCCGCGTCGCTCGTGAACTGA

Upstream 100 bases:

>100_bases
TCAACCTGAATTGATGCAGTGGGCGGTCCGGCGGGAGCCGGACCGGTGAAAACCGGCTTGAACCTAAATCGTAAGTTAAA
CGAAAGAATTGGAGTGGGGT

Downstream 100 bases:

>100_bases
CCGGCTGACGGAGGCGCGCGATGGGCATGAACGTCGGGCAGGACGAAAGCGACGAGGTGATCGCGAACATCAACACGACG
CCGCTCGTCGACGTGATGCT

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MTKRSLAALAASLLMSVAAIDGLVAPQLAYAQASGTASTSDAPTQAAAPTQAPAAAEPAPPPAPAPATTEAVENPYGLGA
LWKNGDFVARFVLILLVIMSMGSWYIMISKFVEQLRANRRAKLADAQLWSAPSLAEGAKLLDEASPFRFIAETAIEAGEH
HDEALLEAVDRNTWIDVSVERSITNVSNRMQDGLAFLATVGSTAPFVGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGE
ALIMTAIGLAVAVPAVLGYNFLVRRNKSVMERVRNFGAQLHTVLLAGSKRPARVPSPAASLVN

Sequences:

>Translated_303_residues
MTKRSLAALAASLLMSVAAIDGLVAPQLAYAQASGTASTSDAPTQAAAPTQAPAAAEPAPPPAPAPATTEAVENPYGLGA
LWKNGDFVARFVLILLVIMSMGSWYIMISKFVEQLRANRRAKLADAQLWSAPSLAEGAKLLDEASPFRFIAETAIEAGEH
HDEALLEAVDRNTWIDVSVERSITNVSNRMQDGLAFLATVGSTAPFVGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGE
ALIMTAIGLAVAVPAVLGYNFLVRRNKSVMERVRNFGAQLHTVLLAGSKRPARVPSPAASLVN
>Mature_302_residues
TKRSLAALAASLLMSVAAIDGLVAPQLAYAQASGTASTSDAPTQAAAPTQAPAAAEPAPPPAPAPATTEAVENPYGLGAL
WKNGDFVARFVLILLVIMSMGSWYIMISKFVEQLRANRRAKLADAQLWSAPSLAEGAKLLDEASPFRFIAETAIEAGEHH
DEALLEAVDRNTWIDVSVERSITNVSNRMQDGLAFLATVGSTAPFVGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGEA
LIMTAIGLAVAVPAVLGYNFLVRRNKSVMERVRNFGAQLHTVLLAGSKRPARVPSPAASLVN

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=198, Percent_Identity=34.8484848484849, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786958, Length=219, Percent_Identity=31.9634703196347, Blast_Score=94, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 31681; Mature: 31550

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRSLAALAASLLMSVAAIDGLVAPQLAYAQASGTASTSDAPTQAAAPTQAPAAAEPAP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPAPAPATTEAVENPYGLGALWKNGDFVARFVLILLVIMSMGSWYIMISKFVEQLRANRR
CCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCH
AKLADAQLWSAPSLAEGAKLLDEASPFRFIAETAIEAGEHHDEALLEAVDRNTWIDVSVE
HHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEHH
RSITNVSNRMQDGLAFLATVGSTAPFVGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGE
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ALIMTAIGLAVAVPAVLGYNFLVRRNKSVMERVRNFGAQLHTVLLAGSKRPARVPSPAAS
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
LVN
HCC
>Mature Secondary Structure 
TKRSLAALAASLLMSVAAIDGLVAPQLAYAQASGTASTSDAPTQAAAPTQAPAAAEPAP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPAPAPATTEAVENPYGLGALWKNGDFVARFVLILLVIMSMGSWYIMISKFVEQLRANRR
CCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCH
AKLADAQLWSAPSLAEGAKLLDEASPFRFIAETAIEAGEHHDEALLEAVDRNTWIDVSVE
HHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEHH
RSITNVSNRMQDGLAFLATVGSTAPFVGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGE
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ALIMTAIGLAVAVPAVLGYNFLVRRNKSVMERVRNFGAQLHTVLLAGSKRPARVPSPAAS
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
LVN
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]