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The map label for this gene is nhaR [H]

Identifier: 116689281

GI number: 116689281

Start: 1392744

End: 1393637

Strand: Reverse

Name: nhaR [H]

Synonym: Bcen2424_1259

Alternate gene names: 116689281

Gene position: 1393637-1392744 (Counterclockwise)

Preceding gene: 116689284

Following gene: 116689280

Centisome position: 40.0

GC content: 71.7

Gene sequence:

>894_bases
ATGCTCAATTTCCGACATCTGTACTATTTCTGGGTCGTGGTGAAGGAAGGCGGCTTCGCGCGTGCGGCCGAGCGGCTCGA
CATGGCCGTGCAGACGATCAGCGCGCAGGTGCGCGAACTGGAGAAATCGCTCGGGCACCAGCTACTGCGCCCCGCCGGGC
GCGGCGTCGCGATGACCGATGCCGGGCAGGCCGCCTTTGCACGCGCGGAAGTCATCTTCGAGATGGGCCGGCAGATTCCC
GACGACGTGCGCGCGGCGGCCAGCCAGCCGACCGTGCGGCTCGCGGTCGGCCTCGCGGACGGCATCTCCAAGCTCGCCGC
GCACGCGATCCTGGCCCCCGTGCTCGACACGCCCACGCTGCGGCTGCTGTGCCACGAGGGCGAGCACGACGCGCTGCTCG
CGGAACTCGCGCTGCATCATCTGGATCTCGTGCTGGCCGGCCACGGCGCGCCGTCCGGGTCGAACCTGCGCGTGACGAGC
GAGCGGCTCGTCGCGTCGCCGGTCGACTGGTACGGGCCCGCGGCACTCGTCACGCCGGCCGCGCGCCAGCGCTTTCCGCA
ATGTCTGGCCGAGCTGCCGGTGCTGCTGCCGACCGCGCATTCGGCATTGCGCGCCCATCTCGACCGATGGCTGGAAAGCG
AGCGGATCGTGCCGCGCGTGGCCGGCGAATTCGAGGACAGCGCGCTGATGGCCGTGTTCGCGGCGCGCGGCCTCGGCGTG
TTTCCACTGAGCGAACTCGGCGCGAACGATGCGTCGCTGCTGCGCGGGCTCAGGCGGCTCGGGCGCGCGGGCGACGTGAC
CGAGGAGATCCACGCGATCCGCTCCCGACGCGGCGAACATCATCCGCTGACGGCCCAATTGCTGGCCGCGGCGCGCGGCG
CGCCGGCCGACTGA

Upstream 100 bases:

>100_bases
GATACGAAAGTGGAAAGCCTGATGATATGACGCCCCGAACTTCGTAAAAATCAGAGAGAATCTGACTTTAGGTTCGGTTT
TTCCGACATATCGCGCTTCG

Downstream 100 bases:

>100_bases
AGCGAGCGCGACATCAAACGAAACTATAATGTCGCCCCGGCCATACGAGATGTGCGCGCGCATCAATCCGGGCACTCCCG
TTGCGCCGCCTCTCGCCGAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MLNFRHLYYFWVVVKEGGFARAAERLDMAVQTISAQVRELEKSLGHQLLRPAGRGVAMTDAGQAAFARAEVIFEMGRQIP
DDVRAAASQPTVRLAVGLADGISKLAAHAILAPVLDTPTLRLLCHEGEHDALLAELALHHLDLVLAGHGAPSGSNLRVTS
ERLVASPVDWYGPAALVTPAARQRFPQCLAELPVLLPTAHSALRAHLDRWLESERIVPRVAGEFEDSALMAVFAARGLGV
FPLSELGANDASLLRGLRRLGRAGDVTEEIHAIRSRRGEHHPLTAQLLAAARGAPAD

Sequences:

>Translated_297_residues
MLNFRHLYYFWVVVKEGGFARAAERLDMAVQTISAQVRELEKSLGHQLLRPAGRGVAMTDAGQAAFARAEVIFEMGRQIP
DDVRAAASQPTVRLAVGLADGISKLAAHAILAPVLDTPTLRLLCHEGEHDALLAELALHHLDLVLAGHGAPSGSNLRVTS
ERLVASPVDWYGPAALVTPAARQRFPQCLAELPVLLPTAHSALRAHLDRWLESERIVPRVAGEFEDSALMAVFAARGLGV
FPLSELGANDASLLRGLRRLGRAGDVTEEIHAIRSRRGEHHPLTAQLLAAARGAPAD
>Mature_297_residues
MLNFRHLYYFWVVVKEGGFARAAERLDMAVQTISAQVRELEKSLGHQLLRPAGRGVAMTDAGQAAFARAEVIFEMGRQIP
DDVRAAASQPTVRLAVGLADGISKLAAHAILAPVLDTPTLRLLCHEGEHDALLAELALHHLDLVLAGHGAPSGSNLRVTS
ERLVASPVDWYGPAALVTPAARQRFPQCLAELPVLLPTAHSALRAHLDRWLESERIVPRVAGEFEDSALMAVFAARGLGV
FPLSELGANDASLLRGLRRLGRAGDVTEEIHAIRSRRGEHHPLTAQLLAAARGAPAD

Specific function: Plays a role in the positive regulation of nhaA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=282, Percent_Identity=32.6241134751773, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1788297, Length=257, Percent_Identity=30.7392996108949, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787601, Length=285, Percent_Identity=23.5087719298246, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31956; Mature: 31956

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNFRHLYYFWVVVKEGGFARAAERLDMAVQTISAQVRELEKSLGHQLLRPAGRGVAMTD
CCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
AGQAAFARAEVIFEMGRQIPDDVRAAASQPTVRLAVGLADGISKLAAHAILAPVLDTPTL
CCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCE
RLLCHEGEHDALLAELALHHLDLVLAGHGAPSGSNLRVTSERLVASPVDWYGPAALVTPA
EEEEECCCHHHHHHHHHHHHHHHHEECCCCCCCCCEEEEHHHHHCCCCCCCCCHHHHCHH
ARQRFPQCLAELPVLLPTAHSALRAHLDRWLESERIVPRVAGEFEDSALMAVFAARGLGV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHCCCCC
FPLSELGANDASLLRGLRRLGRAGDVTEEIHAIRSRRGEHHPLTAQLLAAARGAPAD
CCHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLNFRHLYYFWVVVKEGGFARAAERLDMAVQTISAQVRELEKSLGHQLLRPAGRGVAMTD
CCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
AGQAAFARAEVIFEMGRQIPDDVRAAASQPTVRLAVGLADGISKLAAHAILAPVLDTPTL
CCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCE
RLLCHEGEHDALLAELALHHLDLVLAGHGAPSGSNLRVTSERLVASPVDWYGPAALVTPA
EEEEECCCHHHHHHHHHHHHHHHHEECCCCCCCCCEEEEHHHHHCCCCCCCCCHHHHCHH
ARQRFPQCLAELPVLLPTAHSALRAHLDRWLESERIVPRVAGEFEDSALMAVFAARGLGV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHCCCCC
FPLSELGANDASLLRGLRRLGRAGDVTEEIHAIRSRRGEHHPLTAQLLAAARGAPAD
CCHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2429258; 1630901; 9278503; 3413113; 1316901; 8168494 [H]