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The map label for this gene is pyrR

Identifier: 116515708

GI number: 116515708

Start: 1167840

End: 1168361

Strand: Reverse

Name: pyrR

Synonym: SPD_1134

Alternate gene names: 116515708

Gene position: 1168361-1167840 (Counterclockwise)

Preceding gene: 116516035

Following gene: 116516819

Centisome position: 57.1

GC content: 41.38

Gene sequence:

>522_bases
ATGAAAACAAAAGAAGTTGTAGACGAATTGACCGTCAAACGAGCGATTACGCGTATTACTTATGAGATTATCGAACGCAA
CAAAGATTTGAATAAGATCGTCTTGGCTGGTATTAAAACTCGTGGTGTCTTTATTGCCCACCGAATCCAAGAACGTTTGA
AGCAGTTAGAAAATCTTTCAGTTCCTGTTGTGGAATTGGATACTAAACCTTTCCGTGATGATGTTAAAAGTGGAGAAGAT
ACTTCTTTGGTTTCTGTCGATGTGACAGACCGCGAAGTTATCTTGGTGGATGATGTGCTCTATACAGGTCGTACCATCCG
TGCTGCTATTGATAATATTGTCGGTCATGGTCGTCCTGCGCGTGTGAGTTTAGCAGTTCTAGTCGATCGTGGACATAGAG
AATTGCCAATCCGTCCAGATTACGTTGGAAAAAATATCCCAACCAGTCGTTCTGAAGAAATCATCGTAGAGATGACAGAA
CTTGATGACCAAGACAGAGTTCTGATTACTGAAGAAGCTTAG

Upstream 100 bases:

>100_bases
AAGTAGAAGGGTGAAGTCTATACTGTGTGCAGTAGGGCTCGCTTGGCTATAAATTTCAAGTCTCCTTGTTTAAGGAGACT
TTTCTTTTTGGAGGTTTGTC

Downstream 100 bases:

>100_bases
AAAGTTAAAGGAGTAGCCATGTCAGAAAATCAACAAGCATTGAACCATGTGGTGTCCATGGAAGACCTCACTGTTGATCA
AGTAATGAAATTGATCAAGC

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVFIAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGED
TSLVSVDVTDREVILVDDVLYTGRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
LDDQDRVLITEEA

Sequences:

>Translated_173_residues
MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVFIAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGED
TSLVSVDVTDREVILVDDVLYTGRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
LDDQDRVLITEEA
>Mature_173_residues
MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVFIAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGED
TSLVSVDVTDREVILVDDVLYTGRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
LDDQDRVLITEEA

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRR_STRP2 (Q04K45)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_816603.1
- ProteinModelPortal:   Q04K45
- SMR:   Q04K45
- STRING:   Q04K45
- EnsemblBacteria:   EBSTRT00000020285
- GeneID:   4441450
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1134
- eggNOG:   COG2065
- GeneTree:   EBGT00050000028313
- HOGENOM:   HBG641958
- OMA:   ILDITLY
- ProtClustDB:   PRK05205
- HAMAP:   MF_01219
- InterPro:   IPR000836
- InterPro:   IPR023050

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.9

Molecular weight: Translated: 19609; Mature: 19609

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVFIAHRIQERLKQLENLS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCC
VPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYTGRTIRAAIDNIVGHGRPA
CCEEEECCCCCHHHHCCCCCCEEEEEECCCCEEEEEECHHHCCCHHHHHHHHHHCCCCCC
RVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTELDDQDRVLITEEA
EEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEECC
>Mature Secondary Structure
MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVFIAHRIQERLKQLENLS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCC
VPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYTGRTIRAAIDNIVGHGRPA
CCEEEECCCCCHHHHCCCCCCEEEEEECCCCEEEEEECHHHCCCHHHHHHHHHHCCCCCC
RVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTELDDQDRVLITEEA
EEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA