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The map label for this gene is murQ [H]

Identifier: 116492806

GI number: 116492806

Start: 1035290

End: 1036180

Strand: Reverse

Name: murQ [H]

Synonym: PEPE_1043

Alternate gene names: 116492806

Gene position: 1036180-1035290 (Counterclockwise)

Preceding gene: 116492809

Following gene: 116492805

Centisome position: 56.55

GC content: 37.71

Gene sequence:

>891_bases
ATGATTGATTTAAGTGATTTAACAACGGAAACTCGTAATGAGGAAACTATGAATTTAGACGAGCTATCTACAGCAGAAAT
ATTAAAAATAATGAATTCTGAAGATCAAAAGGTAGCTCAAAGAGTTGGTAAGGTGCTACCTGATATTACACAAGCTGTCA
AACAGATTATCCTTAGTTTTAACAAAAAAGGGCGTTTATTCTACATTGGTGCTGGGACAAGTGGTCGACTAGGTGTTCTA
GATGCTGCAGAGTGTGTACCAACTTTTGGAACAGACCCTAAGATGGTTCAAGGCTTGATTGCAGGTGGAATGAAAGCTAT
GACAATTGCTGTAGAAGGAGCTGAAGATTCGCCAGAGCTAGGTGCTAAGGATTTGCAATCTCAAAACTTAACTAATAAAG
ATATTGTCGTTGGAATTGCTGCAAGTGGACGAACACCATATGTCATTGGTGGATTAGACTATGCCAAAAAAGTTGGTGCA
GCAACAATTAGTCTTGCTTGTAATGATCACGCTAAAATTAGTAAACATGCTGATATTAACATTGAAATATCAGTGGGCCC
TGAGGTTTTAACTGGTTCAACGCGTTTAAAATCGGGGACAGCCCAAAAACTTGTGTTAAACATGCTATCTACAGCCTCAA
TGATCGGGATTGGAAAGGTTTATAAGAACTTAATGGTAGATGTGAAACCCACCAATGCCAAATTAGTGGAACGTTCAAAA
CGTATTATTATGGAAGCAACGGATGTAAGTTATACAGTAGCGAATGATATGTTTGAAAAGGCAGGTAAAGATGTGAAGTT
GGCCATTGTTATGATCTTAACTGATGTCGATTTGAATGAAGCAAAAAAGAGGCTGCAGGTAGCAAAAGGTTTTGTTAGAA
AGACAATATAA

Upstream 100 bases:

>100_bases
AAATTTCTTAAAAATAGAATAATAAAATATTTATTTGAAATGTTATTTCTTTTATTATAAAATGTAACTGTAAATGAAAG
CGCATACAAGGAGGAGCAGC

Downstream 100 bases:

>100_bases
AGTGGGGATGAGAACTTATGTCAGAAACATCTGAAGAAAAAATTAAAAGAATTGCACGTGAAATTTACGGCGCAGTTGGT
GGTATCGAAAATGTTGAAAA

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase 2; N-acetylmuramic acid 6-phosphate hydrolase 2; N-acetylmuramic acid 6-phosphate lyase 2 [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MIDLSDLTTETRNEETMNLDELSTAEILKIMNSEDQKVAQRVGKVLPDITQAVKQIILSFNKKGRLFYIGAGTSGRLGVL
DAAECVPTFGTDPKMVQGLIAGGMKAMTIAVEGAEDSPELGAKDLQSQNLTNKDIVVGIAASGRTPYVIGGLDYAKKVGA
ATISLACNDHAKISKHADINIEISVGPEVLTGSTRLKSGTAQKLVLNMLSTASMIGIGKVYKNLMVDVKPTNAKLVERSK
RIIMEATDVSYTVANDMFEKAGKDVKLAIVMILTDVDLNEAKKRLQVAKGFVRKTI

Sequences:

>Translated_296_residues
MIDLSDLTTETRNEETMNLDELSTAEILKIMNSEDQKVAQRVGKVLPDITQAVKQIILSFNKKGRLFYIGAGTSGRLGVL
DAAECVPTFGTDPKMVQGLIAGGMKAMTIAVEGAEDSPELGAKDLQSQNLTNKDIVVGIAASGRTPYVIGGLDYAKKVGA
ATISLACNDHAKISKHADINIEISVGPEVLTGSTRLKSGTAQKLVLNMLSTASMIGIGKVYKNLMVDVKPTNAKLVERSK
RIIMEATDVSYTVANDMFEKAGKDVKLAIVMILTDVDLNEAKKRLQVAKGFVRKTI
>Mature_296_residues
MIDLSDLTTETRNEETMNLDELSTAEILKIMNSEDQKVAQRVGKVLPDITQAVKQIILSFNKKGRLFYIGAGTSGRLGVL
DAAECVPTFGTDPKMVQGLIAGGMKAMTIAVEGAEDSPELGAKDLQSQNLTNKDIVVGIAASGRTPYVIGGLDYAKKVGA
ATISLACNDHAKISKHADINIEISVGPEVLTGSTRLKSGTAQKLVLNMLSTASMIGIGKVYKNLMVDVKPTNAKLVERSK
RIIMEATDVSYTVANDMFEKAGKDVKLAIVMILTDVDLNEAKKRLQVAKGFVRKTI

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate [H]

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=295, Percent_Identity=50.8474576271186, Blast_Score=284, Evalue=6e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31757; Mature: 31757

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS01272 GCKR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLSDLTTETRNEETMNLDELSTAEILKIMNSEDQKVAQRVGKVLPDITQAVKQIILSF
CCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
NKKGRLFYIGAGTSGRLGVLDAAECVPTFGTDPKMVQGLIAGGMKAMTIAVEGAEDSPEL
CCCCCEEEEECCCCCCEECCCHHHHCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCCC
GAKDLQSQNLTNKDIVVGIAASGRTPYVIGGLDYAKKVGAATISLACNDHAKISKHADIN
CHHHHHHCCCCCCCEEEEEECCCCCCEEEECHHHHHHCCCEEEEEEECCCCCCCCCCCEE
IEISVGPEVLTGSTRLKSGTAQKLVLNMLSTASMIGIGKVYKNLMVDVKPTNAKLVERSK
EEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHH
RIIMEATDVSYTVANDMFEKAGKDVKLAIVMILTDVDLNEAKKRLQVAKGFVRKTI
HHEEEECCCCHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDLSDLTTETRNEETMNLDELSTAEILKIMNSEDQKVAQRVGKVLPDITQAVKQIILSF
CCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
NKKGRLFYIGAGTSGRLGVLDAAECVPTFGTDPKMVQGLIAGGMKAMTIAVEGAEDSPEL
CCCCCEEEEECCCCCCEECCCHHHHCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCCC
GAKDLQSQNLTNKDIVVGIAASGRTPYVIGGLDYAKKVGAATISLACNDHAKISKHADIN
CHHHHHHCCCCCCCEEEEEECCCCCCEEEECHHHHHHCCCEEEEEEECCCCCCCCCCCEE
IEISVGPEVLTGSTRLKSGTAQKLVLNMLSTASMIGIGKVYKNLMVDVKPTNAKLVERSK
EEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHH
RIIMEATDVSYTVANDMFEKAGKDVKLAIVMILTDVDLNEAKKRLQVAKGFVRKTI
HHEEEECCCCHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12566566 [H]