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The map label for this gene is yfeV [C]

Identifier: 116492805

GI number: 116492805

Start: 1033293

End: 1035272

Strand: Reverse

Name: yfeV [C]

Synonym: PEPE_1042

Alternate gene names: 116492805

Gene position: 1035272-1033293 (Counterclockwise)

Preceding gene: 116492806

Following gene: 116492804

Centisome position: 56.5

GC content: 36.46

Gene sequence:

>1980_bases
ATGTCAGAAACATCTGAAGAAAAAATTAAAAGAATTGCACGTGAAATTTACGGCGCAGTTGGTGGTATCGAAAATGTTGA
AAAATTAATTCATTGTATGACTCGTGTCCGAATGACCATTAGAAATGATGACAAAGTAGATATCGAAAAACTGAAAAATA
TTAATGGGGTATTAGGAGTCGTTGAAGAAGACACCCTCCAAGTAATTGTCGGACCAGGAACTGTAAATAAAGTAGCTGAT
GAAATGGTGAAAGAAGCTGGCGTTAAATTGGGTGAACCATTTCCTAATATAGAAATAGATACAACCGGTATGACTGATAA
AGAAATCGTTGAGGCTAAGGCTGCTAAAGTAAAAGCTGCACAAAAAGCTAAGCAAAAACAAACTCCAATTAAGCAAATTT
TAAAATCCATTTCGAATATTTTTATACCGTTAATTCCAGCGTTTGTCGGAGCTGGATTAATTGGTGGCGTAGCTGCGGTA
ATGTCTAATTTAATTGTTGCTGGAGATATAAGTAAAAGCTATACTGATTTTGTCGCAATTTTGAAATTCATTCAAAATGG
TGTATTTTCATATTTAGCAATTTATGTCGGAATTAACGCGGCAACTGAATTTGGTGCAACAGCTGGATTAGGCGGTGTCA
TAGGTGCGGTAACGTTATTACCTGGAATGGATATTAATGCACCTTTGCATAATATTTTTAATGGTCAACCAATGAGCGCT
GGTCAAGGAGGAATTATCGGTGTAATATTTGCCGTTTGGTTACTTTCTTTAATTGAAAAAAAGTTACATAAATGGGTTCC
GGATGCAATTGACATTATAGTAACTCCAGCACTCTCTTTACTTATAATTGGAGTATTTACAATTTTTATTATTATGCCTA
TAGCTGGTGTTATTTCAAGTTCGTTAGTTGGAGCTATTAATTGGATTCTAAATGTCGGCGGAGCATTTTCTGGATTCGTT
TTAGGAGCACTATTCTTGCCGATGGTTATGTTTGGGCTTCATCAAATCTTAACGCCGATTCATATTGAAATGATTAATAA
AACTGGTTCGACCCCATTATTACCAATTTTAGCTATGGCAGGTGCTGGACAAGTTGGAGCTGCGATTGCACTTTGGCTCA
GATGTCGTAAAAATAAACAGCTTACAAATATGATTAAAGGTGCTCTTCCAGTTGGTATTTTAGGTATCGGAGAACCATTA
ATATATGGTGTTACTTTACCATTAGGTCGTCCGTTTATCACAGCTTGTATTGGTGGCGGAATTGGGGGAGCTGTCGTTGG
TGGATTAGGCCATGTTGGTGCCATTGCCATAGGCCCATCAGGATTAGCGTTAGTTCCTTTGATTACGAATGGACATATGA
TGTCTTATGTGCTGGGGTTATTAGCAGGATACGTTGGTGGATTTGTAGCAACATATTTCTTTGGAATTCCAAAGGATGCA
ATTCTTGGAGAAGCAACAACTGTTGAGACAGATGCTTTATCCCAAAATGGAAATAAGAAGGTAATTGATCCAAATGTTGC
AATGACTACGATAACGGCTCCTGTTATTGGTAAGAAAGTTGCAATCGATACAGTAAGTGATCCAATGATGGCCCAGGAAG
TAATGGGAAAAACAGTAGCTATAATACCTGATATTAATTCTAAAATCTATGCCCCGGTAGATGGGAAAGTTACTATGATA
GCAGACACAAAACATGCAATCGGTTTTATGGATAAAATTGGTGAAGAAGTCCTAGTTCATATGGGGGTCGATACTGTTAA
GTTAAATGGCAAGTATTTTAATTTAAATATTCAAGTGGGCGATACTGTTAAACATGGAGATGTATTGGGTACAGTTGATT
GGCAAAAAATTATTGACGCTGATTTTGATCCAGTTACAATGACGATTGTTACTAACACATCCGATTTTAAGATTGACGAA
ATTGAATCAAATATACAGACTAAAGATAATACCGTATTAATGGATAGTAGGATAAAATAA

Upstream 100 bases:

>100_bases
TTATGATCTTAACTGATGTCGATTTGAATGAAGCAAAAAAGAGGCTGCAGGTAGCAAAAGGTTTTGTTAGAAAGACAATA
TAAAGTGGGGATGAGAACTT

Downstream 100 bases:

>100_bases
CTATATTAACTAAGTATTCAAATTTAGAAGATCGGATATTTTCCGGTCTTTTTGGATATATTACTATAATTTATAATTAG
GAGCTAATGTTAAATCTGAC

Product: sucrose-specific PTS system IIBC component

Products: NA

Alternate protein names: Phosphotransferase enzyme IIB component; PTS system EIIB component; Permease IIC component; PTS system EIIC component [H]

Number of amino acids: Translated: 659; Mature: 658

Protein sequence:

>659_residues
MSETSEEKIKRIAREIYGAVGGIENVEKLIHCMTRVRMTIRNDDKVDIEKLKNINGVLGVVEEDTLQVIVGPGTVNKVAD
EMVKEAGVKLGEPFPNIEIDTTGMTDKEIVEAKAAKVKAAQKAKQKQTPIKQILKSISNIFIPLIPAFVGAGLIGGVAAV
MSNLIVAGDISKSYTDFVAILKFIQNGVFSYLAIYVGINAATEFGATAGLGGVIGAVTLLPGMDINAPLHNIFNGQPMSA
GQGGIIGVIFAVWLLSLIEKKLHKWVPDAIDIIVTPALSLLIIGVFTIFIIMPIAGVISSSLVGAINWILNVGGAFSGFV
LGALFLPMVMFGLHQILTPIHIEMINKTGSTPLLPILAMAGAGQVGAAIALWLRCRKNKQLTNMIKGALPVGILGIGEPL
IYGVTLPLGRPFITACIGGGIGGAVVGGLGHVGAIAIGPSGLALVPLITNGHMMSYVLGLLAGYVGGFVATYFFGIPKDA
ILGEATTVETDALSQNGNKKVIDPNVAMTTITAPVIGKKVAIDTVSDPMMAQEVMGKTVAIIPDINSKIYAPVDGKVTMI
ADTKHAIGFMDKIGEEVLVHMGVDTVKLNGKYFNLNIQVGDTVKHGDVLGTVDWQKIIDADFDPVTMTIVTNTSDFKIDE
IESNIQTKDNTVLMDSRIK

Sequences:

>Translated_659_residues
MSETSEEKIKRIAREIYGAVGGIENVEKLIHCMTRVRMTIRNDDKVDIEKLKNINGVLGVVEEDTLQVIVGPGTVNKVAD
EMVKEAGVKLGEPFPNIEIDTTGMTDKEIVEAKAAKVKAAQKAKQKQTPIKQILKSISNIFIPLIPAFVGAGLIGGVAAV
MSNLIVAGDISKSYTDFVAILKFIQNGVFSYLAIYVGINAATEFGATAGLGGVIGAVTLLPGMDINAPLHNIFNGQPMSA
GQGGIIGVIFAVWLLSLIEKKLHKWVPDAIDIIVTPALSLLIIGVFTIFIIMPIAGVISSSLVGAINWILNVGGAFSGFV
LGALFLPMVMFGLHQILTPIHIEMINKTGSTPLLPILAMAGAGQVGAAIALWLRCRKNKQLTNMIKGALPVGILGIGEPL
IYGVTLPLGRPFITACIGGGIGGAVVGGLGHVGAIAIGPSGLALVPLITNGHMMSYVLGLLAGYVGGFVATYFFGIPKDA
ILGEATTVETDALSQNGNKKVIDPNVAMTTITAPVIGKKVAIDTVSDPMMAQEVMGKTVAIIPDINSKIYAPVDGKVTMI
ADTKHAIGFMDKIGEEVLVHMGVDTVKLNGKYFNLNIQVGDTVKHGDVLGTVDWQKIIDADFDPVTMTIVTNTSDFKIDE
IESNIQTKDNTVLMDSRIK
>Mature_658_residues
SETSEEKIKRIAREIYGAVGGIENVEKLIHCMTRVRMTIRNDDKVDIEKLKNINGVLGVVEEDTLQVIVGPGTVNKVADE
MVKEAGVKLGEPFPNIEIDTTGMTDKEIVEAKAAKVKAAQKAKQKQTPIKQILKSISNIFIPLIPAFVGAGLIGGVAAVM
SNLIVAGDISKSYTDFVAILKFIQNGVFSYLAIYVGINAATEFGATAGLGGVIGAVTLLPGMDINAPLHNIFNGQPMSAG
QGGIIGVIFAVWLLSLIEKKLHKWVPDAIDIIVTPALSLLIIGVFTIFIIMPIAGVISSSLVGAINWILNVGGAFSGFVL
GALFLPMVMFGLHQILTPIHIEMINKTGSTPLLPILAMAGAGQVGAAIALWLRCRKNKQLTNMIKGALPVGILGIGEPLI
YGVTLPLGRPFITACIGGGIGGAVVGGLGHVGAIAIGPSGLALVPLITNGHMMSYVLGLLAGYVGGFVATYFFGIPKDAI
LGEATTVETDALSQNGNKKVIDPNVAMTTITAPVIGKKVAIDTVSDPMMAQEVMGKTVAIIPDINSKIYAPVDGKVTMIA
DTKHAIGFMDKIGEEVLVHMGVDTVKLNGKYFNLNIQVGDTVKHGDVLGTVDWQKIIDADFDPVTMTIVTNTSDFKIDEI
ESNIQTKDNTVLMDSRIK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane [H]

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788769, Length=495, Percent_Identity=35.7575757575758, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI1790159, Length=642, Percent_Identity=30.0623052959502, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI48994906, Length=512, Percent_Identity=27.34375, Blast_Score=139, Evalue=7e-34,
Organism=Escherichia coli, GI2367362, Length=464, Percent_Identity=27.1551724137931, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1786894, Length=135, Percent_Identity=30.3703703703704, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788757, Length=127, Percent_Identity=34.6456692913386, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 69575; Mature: 69444

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETSEEKIKRIAREIYGAVGGIENVEKLIHCMTRVRMTIRNDDKVDIEKLKNINGVLGV
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEE
VEEDTLQVIVGPGTVNKVADEMVKEAGVKLGEPFPNIEIDTTGMTDKEIVEAKAAKVKAA
EECCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHH
QKAKQKQTPIKQILKSISNIFIPLIPAFVGAGLIGGVAAVMSNLIVAGDISKSYTDFVAI
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHH
LKFIQNGVFSYLAIYVGINAATEFGATAGLGGVIGAVTLLPGMDINAPLHNIFNGQPMSA
HHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCC
GQGGIIGVIFAVWLLSLIEKKLHKWVPDAIDIIVTPALSLLIIGVFTIFIIMPIAGVISS
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLVGAINWILNVGGAFSGFVLGALFLPMVMFGLHQILTPIHIEMINKTGSTPLLPILAMA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHC
GAGQVGAAIALWLRCRKNKQLTNMIKGALPVGILGIGEPLIYGVTLPLGRPFITACIGGG
CCCHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCEEEEEECCCCCHHHHHHHCCC
IGGAVVGGLGHVGAIAIGPSGLALVPLITNGHMMSYVLGLLAGYVGGFVATYFFGIPKDA
HHHHHHHCCCCCCEEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ILGEATTVETDALSQNGNKKVIDPNVAMTTITAPVIGKKVAIDTVSDPMMAQEVMGKTVA
HCCCCCEEEHHHHCCCCCCEEECCCCEEEEEEHHHCCCEEEEECCCCHHHHHHHCCCEEE
IIPDINSKIYAPVDGKVTMIADTKHAIGFMDKIGEEVLVHMGVDTVKLNGKYFNLNIQVG
EEECCCCEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEEEEC
DTVKHGDVLGTVDWQKIIDADFDPVTMTIVTNTSDFKIDEIESNIQTKDNTVLMDSRIK
CCEECCCEEECCCHHHHHCCCCCCEEEEEEECCCCCCHHHHHCCCCCCCCEEEECCCCC
>Mature Secondary Structure 
SETSEEKIKRIAREIYGAVGGIENVEKLIHCMTRVRMTIRNDDKVDIEKLKNINGVLGV
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEE
VEEDTLQVIVGPGTVNKVADEMVKEAGVKLGEPFPNIEIDTTGMTDKEIVEAKAAKVKAA
EECCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHH
QKAKQKQTPIKQILKSISNIFIPLIPAFVGAGLIGGVAAVMSNLIVAGDISKSYTDFVAI
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHH
LKFIQNGVFSYLAIYVGINAATEFGATAGLGGVIGAVTLLPGMDINAPLHNIFNGQPMSA
HHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCC
GQGGIIGVIFAVWLLSLIEKKLHKWVPDAIDIIVTPALSLLIIGVFTIFIIMPIAGVISS
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLVGAINWILNVGGAFSGFVLGALFLPMVMFGLHQILTPIHIEMINKTGSTPLLPILAMA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHC
GAGQVGAAIALWLRCRKNKQLTNMIKGALPVGILGIGEPLIYGVTLPLGRPFITACIGGG
CCCHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCEEEEEECCCCCHHHHHHHCCC
IGGAVVGGLGHVGAIAIGPSGLALVPLITNGHMMSYVLGLLAGYVGGFVATYFFGIPKDA
HHHHHHHCCCCCCEEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ILGEATTVETDALSQNGNKKVIDPNVAMTTITAPVIGKKVAIDTVSDPMMAQEVMGKTVA
HCCCCCEEEHHHHCCCCCCEEECCCCEEEEEEHHHCCCEEEEECCCCHHHHHHHCCCEEE
IIPDINSKIYAPVDGKVTMIADTKHAIGFMDKIGEEVLVHMGVDTVKLNGKYFNLNIQVG
EEECCCCEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEEEEC
DTVKHGDVLGTVDWQKIIDADFDPVTMTIVTNTSDFKIDEIESNIQTKDNTVLMDSRIK
CCEECCCEEECCCHHHHHCCCCCCEEEEEEECCCCCCHHHHHCCCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA