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The map label for this gene is msrB [H]

Identifier: 116492717

GI number: 116492717

Start: 954848

End: 955291

Strand: Reverse

Name: msrB [H]

Synonym: PEPE_0954

Alternate gene names: 116492717

Gene position: 955291-954848 (Counterclockwise)

Preceding gene: 116492718

Following gene: 116492716

Centisome position: 52.13

GC content: 39.19

Gene sequence:

>444_bases
ATGAATTCAAATAACTGGTCCAAAGCAGAGCTAAAAAAGAAACTGTCTCCTGAAGAATATGAGGTTACACAAAATGCTGC
TACTGAACATCCTTTCACCGGTAAATACGATAATTTTTACCAAAAGGGGATTTACGTTGATGTCGTCAGTGGTGAGCCAC
TTTTTAGTTCCACCGATAAATATGACGCTCACTGTGGTTGGCCTTCTTTTACCAAACCTATTGACCCTAAATTAGTGGTT
AATCATCGAGATTCTTCTTATGGCATGGAACGAGTGGAAGTCCGCAGCAAGGATGCTAACTCTCACTTAGGACACGTATT
TGATGATGGGCCTCTCGATCAAGGTGGAAATCGTTATTGTATCAATTCGGCTGCCCTGAAATTCATTGCATATGACGATT
TAGAAGCGCATAATCTAGGTTATTTAAAGAAACTATTTAATTAG

Upstream 100 bases:

>100_bases
ATTAATAAGTTTTAACTTGAGCTTTTATTTTGTAAGCATCTTAATCCCCTAAAAGACATGAATGTTTTATAATCGATGTT
ATAGGTAAGGGGGAATTTAA

Downstream 100 bases:

>100_bases
GAGCGTGATTTACTTATGGAAGAAACTGCTATTTTTGCCGGTGGGTGTTTTTGGTGCATGGTAGAACCTTTTGAAACTCA
ACCTGGTATTATCAACGTTG

Product: peptide methionine sulfoxide reductase domain-containing protein

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MNSNNWSKAELKKKLSPEEYEVTQNAATEHPFTGKYDNFYQKGIYVDVVSGEPLFSSTDKYDAHCGWPSFTKPIDPKLVV
NHRDSSYGMERVEVRSKDANSHLGHVFDDGPLDQGGNRYCINSAALKFIAYDDLEAHNLGYLKKLFN

Sequences:

>Translated_147_residues
MNSNNWSKAELKKKLSPEEYEVTQNAATEHPFTGKYDNFYQKGIYVDVVSGEPLFSSTDKYDAHCGWPSFTKPIDPKLVV
NHRDSSYGMERVEVRSKDANSHLGHVFDDGPLDQGGNRYCINSAALKFIAYDDLEAHNLGYLKKLFN
>Mature_147_residues
MNSNNWSKAELKKKLSPEEYEVTQNAATEHPFTGKYDNFYQKGIYVDVVSGEPLFSSTDKYDAHCGWPSFTKPIDPKLVV
NHRDSSYGMERVEVRSKDANSHLGHVFDDGPLDQGGNRYCINSAALKFIAYDDLEAHNLGYLKKLFN

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=127, Percent_Identity=48.8188976377953, Blast_Score=124, Evalue=3e-29,
Organism=Homo sapiens, GI301336162, Length=127, Percent_Identity=48.8188976377953, Blast_Score=124, Evalue=3e-29,
Organism=Homo sapiens, GI73089054, Length=127, Percent_Identity=48.8188976377953, Blast_Score=124, Evalue=3e-29,
Organism=Homo sapiens, GI37620216, Length=127, Percent_Identity=48.8188976377953, Blast_Score=124, Evalue=4e-29,
Organism=Homo sapiens, GI117606353, Length=129, Percent_Identity=44.1860465116279, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI1788077, Length=126, Percent_Identity=46.8253968253968, Blast_Score=123, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17553450, Length=132, Percent_Identity=41.6666666666667, Blast_Score=112, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI115532676, Length=132, Percent_Identity=41.6666666666667, Blast_Score=112, Evalue=9e-26,
Organism=Saccharomyces cerevisiae, GI6319816, Length=119, Percent_Identity=38.655462184874, Blast_Score=90, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221378664, Length=123, Percent_Identity=51.219512195122, Blast_Score=133, Evalue=5e-32,
Organism=Drosophila melanogaster, GI221378662, Length=130, Percent_Identity=48.4615384615385, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24645799, Length=126, Percent_Identity=50, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI45553335, Length=126, Percent_Identity=50, Blast_Score=130, Evalue=3e-31,
Organism=Drosophila melanogaster, GI21356369, Length=126, Percent_Identity=50, Blast_Score=130, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24645804, Length=137, Percent_Identity=45.985401459854, Blast_Score=125, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24645801, Length=137, Percent_Identity=45.985401459854, Blast_Score=125, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 16685; Mature: 16685

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSNNWSKAELKKKLSPEEYEVTQNAATEHPFTGKYDNFYQKGIYVDVVSGEPLFSSTDK
CCCCCCCHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCHHHCCEEEEEECCCCCCCCCCC
YDAHCGWPSFTKPIDPKLVVNHRDSSYGMERVEVRSKDANSHLGHVFDDGPLDQGGNRYC
CCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEE
INSAALKFIAYDDLEAHNLGYLKKLFN
EHHHEEEEEEECCCCCCCHHHHHHHCC
>Mature Secondary Structure
MNSNNWSKAELKKKLSPEEYEVTQNAATEHPFTGKYDNFYQKGIYVDVVSGEPLFSSTDK
CCCCCCCHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCHHHCCEEEEEECCCCCCCCCCC
YDAHCGWPSFTKPIDPKLVVNHRDSSYGMERVEVRSKDANSHLGHVFDDGPLDQGGNRYC
CCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEE
INSAALKFIAYDDLEAHNLGYLKKLFN
EHHHEEEEEEECCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12566566 [H]