Click here to switch to the map view.

The map label for this gene is phoP [H]

Identifier: 116492234

GI number: 116492234

Start: 482000

End: 482704

Strand: Direct

Name: phoP [H]

Synonym: PEPE_0431

Alternate gene names: 116492234

Gene position: 482000-482704 (Clockwise)

Preceding gene: 116492233

Following gene: 116492235

Centisome position: 26.3

GC content: 35.74

Gene sequence:

>705_bases
ATGTCAAAGACGATATTAGTTGTAGATGATGAGCCAGCAATTGTGACTTTAATTACTTATAATTTGGAACAAGCTAATTA
TCAAGTTGTGAGTGTGGATAACGGTTTAGATGCGGTGGAAATCGTCCAAAAGGGCTTAGTTGATTTTGTGATTATGGATT
TAATGCTCCCTCAATTGGATGGAATTGAAGCTACCAAACAAATTCGCAAGTTTGATGAACAAATTCCAATTATTATGTTG
ACGGCTAAGACTAGTCAAGTTGATAAAATATTGGGATTGGAATTAGGGGCAGATGATTATATTACCAAACCATTTAGTCC
TCAGGAGCTTCTTTCACGGATTAAAGTAATCTTGCGACGGACTGATCGGGCAATTAATTTGGCTGAAATTGATCCAACTC
TACAAGCAGAAAATATCGCCATTGATTTCAAAAGAATGGTGGTTAAGAAGAATAATGAAAAAATTCAATTAACACCCAAT
GAATTTAAACTATTAAGGTATTTATACAAAAATGCCAACCAAGTTTTATCACGCGATCAAATTTTGGAGAAAGTTTGGGG
ATATGAATATGGGGGACAGACCCGTATTGTAGATATCCACATCAGTCATTTGAGGGATAAACTGGAAAATGATCCCAAAC
ATCCACAGTTGATCAAAACCATTAGGGGGTTTGGATATGAGTTCGTCTCGAAAAAAGGCGATTAA

Upstream 100 bases:

>100_bases
GCTAACGTTCAAGGTGTGATGGACGGGGATTTCGATGATTTTATCAATGCTTATTTGCAATGGAAATTGAAAGAAGATAA
TCCAAAATAGGGGGATTCGG

Downstream 100 bases:

>100_bases
GCGTACCGTGCAATTTGGTTTTGCTAGTCTAATCGGAAATGCCTTTATGGCTTTTCTGGTGTATAAATTAATTGTAAAAG
AAAATCCACGAGTAACTAAG

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MSKTILVVDDEPAIVTLITYNLEQANYQVVSVDNGLDAVEIVQKGLVDFVIMDLMLPQLDGIEATKQIRKFDEQIPIIML
TAKTSQVDKILGLELGADDYITKPFSPQELLSRIKVILRRTDRAINLAEIDPTLQAENIAIDFKRMVVKKNNEKIQLTPN
EFKLLRYLYKNANQVLSRDQILEKVWGYEYGGQTRIVDIHISHLRDKLENDPKHPQLIKTIRGFGYEFVSKKGD

Sequences:

>Translated_234_residues
MSKTILVVDDEPAIVTLITYNLEQANYQVVSVDNGLDAVEIVQKGLVDFVIMDLMLPQLDGIEATKQIRKFDEQIPIIML
TAKTSQVDKILGLELGADDYITKPFSPQELLSRIKVILRRTDRAINLAEIDPTLQAENIAIDFKRMVVKKNNEKIQLTPN
EFKLLRYLYKNANQVLSRDQILEKVWGYEYGGQTRIVDIHISHLRDKLENDPKHPQLIKTIRGFGYEFVSKKGD
>Mature_233_residues
SKTILVVDDEPAIVTLITYNLEQANYQVVSVDNGLDAVEIVQKGLVDFVIMDLMLPQLDGIEATKQIRKFDEQIPIIMLT
AKTSQVDKILGLELGADDYITKPFSPQELLSRIKVILRRTDRAINLAEIDPTLQAENIAIDFKRMVVKKNNEKIQLTPNE
FKLLRYLYKNANQVLSRDQILEKVWGYEYGGQTRIVDIHISHLRDKLENDPKHPQLIKTIRGFGYEFVSKKGD

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=36.9098712446352, Blast_Score=170, Evalue=8e-44,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=37.9310344827586, Blast_Score=162, Evalue=1e-41,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=35.1351351351351, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=37.7777777777778, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1786911, Length=232, Percent_Identity=36.2068965517241, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=36.4035087719298, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=33.1858407079646, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=36.6812227074236, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=32.1739130434783, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=32.15859030837, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=31.140350877193, Blast_Score=123, Evalue=9e-30,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=31.4410480349345, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=30.2222222222222, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=35.6223175965665, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=32.0754716981132, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI145693157, Length=102, Percent_Identity=34.3137254901961, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790437, Length=117, Percent_Identity=31.6239316239316, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789149, Length=114, Percent_Identity=35.0877192982456, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788905, Length=100, Percent_Identity=32, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1788222, Length=115, Percent_Identity=33.9130434782609, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788191, Length=119, Percent_Identity=30.2521008403361, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1790299, Length=101, Percent_Identity=28.7128712871287, Blast_Score=60, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=108, Percent_Identity=35.1851851851852, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26811; Mature: 26679

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTILVVDDEPAIVTLITYNLEQANYQVVSVDNGLDAVEIVQKGLVDFVIMDLMLPQLD
CCCEEEEECCCCCEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCC
GIEATKQIRKFDEQIPIIMLTAKTSQVDKILGLELGADDYITKPFSPQELLSRIKVILRR
CHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCEECCCCCCCCCCCHHHHHHHHHHHHHH
TDRAINLAEIDPTLQAENIAIDFKRMVVKKNNEKIQLTPNEFKLLRYLYKNANQVLSRDQ
CCCCEEEECCCCCCCCCCEEEHHHHHHEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHH
ILEKVWGYEYGGQTRIVDIHISHLRDKLENDPKHPQLIKTIRGFGYEFVSKKGD
HHHHHCCCCCCCCEEEEEEEHHHHHHHHHCCCCCHHHHHHHHHCCHHHHCCCCC
>Mature Secondary Structure 
SKTILVVDDEPAIVTLITYNLEQANYQVVSVDNGLDAVEIVQKGLVDFVIMDLMLPQLD
CCEEEEECCCCCEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCC
GIEATKQIRKFDEQIPIIMLTAKTSQVDKILGLELGADDYITKPFSPQELLSRIKVILRR
CHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCEECCCCCCCCCCCHHHHHHHHHHHHHH
TDRAINLAEIDPTLQAENIAIDFKRMVVKKNNEKIQLTPNEFKLLRYLYKNANQVLSRDQ
CCCCEEEECCCCCCCCCCEEEHHHHHHEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHH
ILEKVWGYEYGGQTRIVDIHISHLRDKLENDPKHPQLIKTIRGFGYEFVSKKGD
HHHHHCCCCCCCCEEEEEEEHHHHHHHHHCCCCCHHHHHHHHHCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]