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The map label for this gene is gmuR [H]

Identifier: 116492155

GI number: 116492155

Start: 398018

End: 398740

Strand: Direct

Name: gmuR [H]

Synonym: PEPE_0352

Alternate gene names: 116492155

Gene position: 398018-398740 (Clockwise)

Preceding gene: 116492153

Following gene: 116492156

Centisome position: 21.72

GC content: 35.55

Gene sequence:

>723_bases
ATGGAAGATCTGATCTACAAAAAAATCATTCACGACCTTAAAAAAAGAATCTTTAATAATGAATTTCCAACGATGCGTTT
ACCAGATGAACGTTCGTTAACTACGGAATATGACGTGAGTCGTAGTTCCGTCAAAAGAGCATTAAGTTCCATGGCACATG
AGGGAATAGTTTTTAAAAAACGAGGTTCCGGAACTTTTATCAATCCGCTCTATTTGAAAAGTCAATCCTCTTTTAATTAT
GAAGGATCTAATCTAGGTATCACAGATAGTTTGAAATCCAATGGTAAAAAGCAGGGAATTAAAGTGCTAGATTTTTCAGT
AGTTCCTGCTACGGAAAATATGAAGACAGATTTATTTTTAAATGAAGGTGACTTTGTCTATCAAGTTCGTCGCTTACGTT
TGTTAGATGATGAACCAATCATGATTGAAACGGGCTATATTCCAATTAAAATTGTGCCGGAGTTATCCAAGGCCATTGTG
GAAAAATCGATTTTTAATTATTTAGAGGACGCTCAAGGCCAACACGTAACACGTTCGTTTATGTCGATTCAAGTAGAACC
CTCCAATGCTGAAGATCAAAAACTTTTAGGATTAACCGAAAATGAACCCGTCGGTGTTATGTCCGGAATTTTCTTTATGG
ATGATGGTACGCCGTTTGAAATTTCAAATATGCGAATTCACTACAAATATATGAATTACAGCACATTTGTGTCTGTCGAT
TAA

Upstream 100 bases:

>100_bases
TACCCTTGTATTTTAGCATAGGAAAAATCGTTAGTTAATAAAATCAAAGCATTCAAGTTTGCTATAATGGTGAAAGCAAT
TAACAATGGGAGATAGTTTA

Downstream 100 bases:

>100_bases
GCAAAGCATCTAATTTTGATTAGATGCTTTTTTACGTTAGAATAGCCGTTGAAAAGGTGATTTCGTATCATTTTTAAAAT
TGGACCGTATCAATTTAAAA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: Glucomannan utilization operon repressor; Glucomannan utilization protein R [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MEDLIYKKIIHDLKKRIFNNEFPTMRLPDERSLTTEYDVSRSSVKRALSSMAHEGIVFKKRGSGTFINPLYLKSQSSFNY
EGSNLGITDSLKSNGKKQGIKVLDFSVVPATENMKTDLFLNEGDFVYQVRRLRLLDDEPIMIETGYIPIKIVPELSKAIV
EKSIFNYLEDAQGQHVTRSFMSIQVEPSNAEDQKLLGLTENEPVGVMSGIFFMDDGTPFEISNMRIHYKYMNYSTFVSVD

Sequences:

>Translated_240_residues
MEDLIYKKIIHDLKKRIFNNEFPTMRLPDERSLTTEYDVSRSSVKRALSSMAHEGIVFKKRGSGTFINPLYLKSQSSFNY
EGSNLGITDSLKSNGKKQGIKVLDFSVVPATENMKTDLFLNEGDFVYQVRRLRLLDDEPIMIETGYIPIKIVPELSKAIV
EKSIFNYLEDAQGQHVTRSFMSIQVEPSNAEDQKLLGLTENEPVGVMSGIFFMDDGTPFEISNMRIHYKYMNYSTFVSVD
>Mature_240_residues
MEDLIYKKIIHDLKKRIFNNEFPTMRLPDERSLTTEYDVSRSSVKRALSSMAHEGIVFKKRGSGTFINPLYLKSQSSFNY
EGSNLGITDSLKSNGKKQGIKVLDFSVVPATENMKTDLFLNEGDFVYQVRRLRLLDDEPIMIETGYIPIKIVPELSKAIV
EKSIFNYLEDAQGQHVTRSFMSIQVEPSNAEDQKLLGLTENEPVGVMSGIFFMDDGTPFEISNMRIHYKYMNYSTFVSVD

Specific function: Transcriptional repressor of the gmuBACDREFG operon which is involved in the uptake and degradation of glucomannan [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790118, Length=214, Percent_Identity=27.1028037383178, Blast_Score=94, Evalue=5e-21,
Organism=Escherichia coli, GI1786950, Length=221, Percent_Identity=26.2443438914027, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI87082252, Length=224, Percent_Identity=24.1071428571429, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788418, Length=205, Percent_Identity=27.8048780487805, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27439; Mature: 27439

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDLIYKKIIHDLKKRIFNNEFPTMRLPDERSLTTEYDVSRSSVKRALSSMAHEGIVFKK
CCHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHCCCHHHHHHHHHHHHHCCEEEEE
RGSGTFINPLYLKSQSSFNYEGSNLGITDSLKSNGKKQGIKVLDFSVVPATENMKTDLFL
CCCCCEECEEEEECCCCCCCCCCCCCEEHHHHCCCCCCCEEEEEEEEECCCCCCCEEEEE
NEGDFVYQVRRLRLLDDEPIMIETGYIPIKIVPELSKAIVEKSIFNYLEDAQGQHVTRSF
CCCCCEEEEEHHHCCCCCCEEEECCCEEEEECHHHHHHHHHHHHHHHHHHCCCCHHEEEE
MSIQVEPSNAEDQKLLGLTENEPVGVMSGIFFMDDGTPFEISNMRIHYKYMNYSTFVSVD
EEEEECCCCCCCCEEECCCCCCCCEEEEEEEEECCCCCEEEECEEEEEEEECEEEEEEEC
>Mature Secondary Structure
MEDLIYKKIIHDLKKRIFNNEFPTMRLPDERSLTTEYDVSRSSVKRALSSMAHEGIVFKK
CCHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHCCCHHHHHHHHHHHHHCCEEEEE
RGSGTFINPLYLKSQSSFNYEGSNLGITDSLKSNGKKQGIKVLDFSVVPATENMKTDLFL
CCCCCEECEEEEECCCCCCCCCCCCCEEHHHHCCCCCCCEEEEEEEEECCCCCCCEEEEE
NEGDFVYQVRRLRLLDDEPIMIETGYIPIKIVPELSKAIVEKSIFNYLEDAQGQHVTRSF
CCCCCEEEEEHHHCCCCCCEEEECCCEEEEECHHHHHHHHHHHHHHHHHHCCCCHHEEEE
MSIQVEPSNAEDQKLLGLTENEPVGVMSGIFFMDDGTPFEISNMRIHYKYMNYSTFVSVD
EEEEECCCCCCCCEEECCCCCCCCEEEEEEEEECCCCCEEEECEEEEEEEECEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]