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The map label for this gene is ycsN [H]

Identifier: 116492150

GI number: 116492150

Start: 394712

End: 395650

Strand: Direct

Name: ycsN [H]

Synonym: PEPE_0347

Alternate gene names: 116492150

Gene position: 394712-395650 (Clockwise)

Preceding gene: 116492148

Following gene: 116492153

Centisome position: 21.54

GC content: 38.45

Gene sequence:

>939_bases
ATGAAAAAGATTAACATTGGTGGTATGCGCGTTTCTAACGTTGCTTTAGGTATCATGCGAATGAATGCGCTATCAGACAA
AGACGCAGCAACGGCCATTGAGGCTGCTTTTGATATAGGAATTAATTATATTGATTCAGCTGATATTTATGGACATGGTG
AATCCAGCAAAAAATTCCGTGAAGGACTAAAGCTATCGAGTGTAAATCGTGAGGATTTGTACATTCAATCTAAGGGTGGA
ATTGAAAATAGTAATAGTGGCGACATCCCTTATGGCAATCGCTATAACTTTAGTAAAGAGCACATCATTGGTGCGGTCGA
CGGCGAACTTCAGCGTTTAGGTGTGGACTATCTAGATGCCTTTTTACTTCATCGACCTGATCCACTAATGGAACCAGCAC
AAATCGCAGAAGCTTTTGATGAACTTCAAGCTGCTGGTAAAGTACGTCATTTTGGGGTTTCTAATTTTAATCCAATGCAG
GTTGAATTAGTTCAAAAGTACACTAAGCAAAAACTTGAAATTAATCAGCTTCAATTTGGAATTATGCATACAGGAATGAT
TGATTTTGGCATGCATACTAACATGTTCGACGAACGTAGTATTGATCATGATGGCCAGATTTTGGAATACGCAAGATTAC
ACGATATGACAATCCAAGCTTGGTCACCTTACCAATATGGTTTCTTTGATGGTGTATTTATTGATAATCCTAAATTCCCA
GAATTAAATAAGAAGATGAAACAAATTGCAGATATTTATGGTGTAACTAAGAATGCCATTGCAACCGCGTGGATTTTGAG
ACATCCTGCGCAATTCCAAGTATTACTGGGAACCATGAATCCTCAGCATATTAAAGAATCAGCTGCTGGTAGTGATGTCG
AACTTACTGGTCAAGAATGGTATGACATTTACTACGCTGCTGGAAACGACATGCCTTAA

Upstream 100 bases:

>100_bases
AATAGTATGAAAAGTAGCTTTCTTTTTAATGTTGTATAGTGAAGTTTAATGTTATCATGGAGCTATAATTTATTATATAG
TGGATGGAGGTTCTTGTACT

Downstream 100 bases:

>100_bases
ATTAAAAAATAGTAACGTCCCTTACTTTATAGTGAGGCGCGTTACTATTTTTTATTTCTTTTGAATGGCTACTCGTAAAA
TTGTTTTACGCTGTGCTTCT

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKKINIGGMRVSNVALGIMRMNALSDKDAATAIEAAFDIGINYIDSADIYGHGESSKKFREGLKLSSVNREDLYIQSKGG
IENSNSGDIPYGNRYNFSKEHIIGAVDGELQRLGVDYLDAFLLHRPDPLMEPAQIAEAFDELQAAGKVRHFGVSNFNPMQ
VELVQKYTKQKLEINQLQFGIMHTGMIDFGMHTNMFDERSIDHDGQILEYARLHDMTIQAWSPYQYGFFDGVFIDNPKFP
ELNKKMKQIADIYGVTKNAIATAWILRHPAQFQVLLGTMNPQHIKESAAGSDVELTGQEWYDIYYAAGNDMP

Sequences:

>Translated_312_residues
MKKINIGGMRVSNVALGIMRMNALSDKDAATAIEAAFDIGINYIDSADIYGHGESSKKFREGLKLSSVNREDLYIQSKGG
IENSNSGDIPYGNRYNFSKEHIIGAVDGELQRLGVDYLDAFLLHRPDPLMEPAQIAEAFDELQAAGKVRHFGVSNFNPMQ
VELVQKYTKQKLEINQLQFGIMHTGMIDFGMHTNMFDERSIDHDGQILEYARLHDMTIQAWSPYQYGFFDGVFIDNPKFP
ELNKKMKQIADIYGVTKNAIATAWILRHPAQFQVLLGTMNPQHIKESAAGSDVELTGQEWYDIYYAAGNDMP
>Mature_312_residues
MKKINIGGMRVSNVALGIMRMNALSDKDAATAIEAAFDIGINYIDSADIYGHGESSKKFREGLKLSSVNREDLYIQSKGG
IENSNSGDIPYGNRYNFSKEHIIGAVDGELQRLGVDYLDAFLLHRPDPLMEPAQIAEAFDELQAAGKVRHFGVSNFNPMQ
VELVQKYTKQKLEINQLQFGIMHTGMIDFGMHTNMFDERSIDHDGQILEYARLHDMTIQAWSPYQYGFFDGVFIDNPKFP
ELNKKMKQIADIYGVTKNAIATAWILRHPAQFQVLLGTMNPQHIKESAAGSDVELTGQEWYDIYYAAGNDMP

Specific function: Unknown

COG id: COG4989

COG function: function code R; Predicted oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=319, Percent_Identity=24.7648902821317, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI27436962, Length=315, Percent_Identity=24.4444444444444, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI27436966, Length=315, Percent_Identity=24.4444444444444, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI27436969, Length=313, Percent_Identity=24.6006389776358, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI4504825, Length=320, Percent_Identity=24.375, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI48994888, Length=318, Percent_Identity=30.8176100628931, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1788070, Length=331, Percent_Identity=25.6797583081571, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87081735, Length=318, Percent_Identity=22.6415094339623, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788081, Length=284, Percent_Identity=26.7605633802817, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082198, Length=295, Percent_Identity=26.1016949152542, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789375, Length=314, Percent_Identity=23.5668789808917, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787674, Length=279, Percent_Identity=26.5232974910394, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786400, Length=175, Percent_Identity=27.4285714285714, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17561298, Length=312, Percent_Identity=25, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538386, Length=311, Percent_Identity=24.1157556270096, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=343, Percent_Identity=22.1574344023324, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24644950, Length=303, Percent_Identity=24.4224422442244, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35099; Mature: 35099

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKINIGGMRVSNVALGIMRMNALSDKDAATAIEAAFDIGINYIDSADIYGHGESSKKFR
CCEECCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHH
EGLKLSSVNREDLYIQSKGGIENSNSGDIPYGNRYNFSKEHIIGAVDGELQRLGVDYLDA
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHEEECCCCHHHHHCHHHHHH
FLLHRPDPLMEPAQIAEAFDELQAAGKVRHFGVSNFNPMQVELVQKYTKQKLEINQLQFG
HHHCCCCCCCCHHHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IMHTGMIDFGMHTNMFDERSIDHDGQILEYARLHDMTIQAWSPYQYGFFDGVFIDNPKFP
HHCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHCEEEEECCCCCCCCCCCEEECCCCCC
ELNKKMKQIADIYGVTKNAIATAWILRHPAQFQVLLGTMNPQHIKESAAGSDVELTGQEW
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHCCCCCEEECCCCE
YDIYYAAGNDMP
EEEEEECCCCCC
>Mature Secondary Structure
MKKINIGGMRVSNVALGIMRMNALSDKDAATAIEAAFDIGINYIDSADIYGHGESSKKFR
CCEECCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHH
EGLKLSSVNREDLYIQSKGGIENSNSGDIPYGNRYNFSKEHIIGAVDGELQRLGVDYLDA
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHEEECCCCHHHHHCHHHHHH
FLLHRPDPLMEPAQIAEAFDELQAAGKVRHFGVSNFNPMQVELVQKYTKQKLEINQLQFG
HHHCCCCCCCCHHHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IMHTGMIDFGMHTNMFDERSIDHDGQILEYARLHDMTIQAWSPYQYGFFDGVFIDNPKFP
HHCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHCEEEEECCCCCCCCCCCEEECCCCCC
ELNKKMKQIADIYGVTKNAIATAWILRHPAQFQVLLGTMNPQHIKESAAGSDVELTGQEW
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHCCCCCEEECCCCE
YDIYYAAGNDMP
EEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]