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The map label for this gene is codA [H]

Identifier: 116492045

GI number: 116492045

Start: 284528

End: 285760

Strand: Direct

Name: codA [H]

Synonym: PEPE_0241

Alternate gene names: 116492045

Gene position: 284528-285760 (Clockwise)

Preceding gene: 116492044

Following gene: 116492046

Centisome position: 15.53

GC content: 34.96

Gene sequence:

>1233_bases
ATGTTAATTAAAAACGTTCATATCGAAAATGATCCTGAAGTAAAAGATGTTAGAATCGAAAATGGAATTTTTAAAGCAAT
TGGTAAAAATCTTGAAGCATCTGATGACGAGGTGATTGATGCCAATGGAAAATTACTTTTACCACCCTTTATTGATTCAC
ATGTGCATTTAGATGCGACCTTAACAGCGGGAGATCCCGAATGGAATGAAACTGGAACTTTATTTGATGGAATTCGTATT
TGGTCAGAACGCAAACAAACCTTAACTAAAAAAGAGACTAAAGAACGCGCTATTCAAACGTTGAAAAATCAAGCTAGCCA
TGGAATTCAATTCGTCCGCAGCCATGTTGATACTACCGATCCTAGTTTTACAGCTCTAGAGGCTTTATTAGAAGTAAAAG
ATGAAGTAAAAGATTTTATGGAATTGCAATTGGTAGCCTTTCCGCAGGAAGGTATTTTATCGTTTAAAAATGGTAAAAAC
CTGATTAAACAAGCGGTTGAAATGGGCGTCGATGTTATTGGAGCAATTCCGCATTTTGAATTTAATCGTGACTACGGCGT
GGATTCCTTAAAGTATATTGTTGAGCTTGCTGAAAAATATGACAAACTTATCGATGTACATTGTGATGAAATTGATGATC
CTAATTCACGTCACCTAGAAGTCTTAGCTACTTTAGCTTATGAAAGTGGTTTAAAAAATAAAGTCACTGCTAGCCATACT
ACGGCAATGGGCTCATATAACGATGCGTATGTTTATAAGTTAATGCGTCTTTTAGAGATGTCCAATATTAATATGGTATG
CAACCCATTAATTAACATGCACCTGGGTGGCCGGTTTGATACGTATCCAAAACGACGCGGGTTAACCCGCGTTAAGGAAC
TTTTGGAAAATAACGTTAATGTTTCCTTCGGCGAAGATGATATAAAAGACCCTTGGTATCCAATGGGAGACGGAAACATG
TTAGATTCGATTCATATGGGAATTCATGCAACTCAATTGATGGGATATTCGCAAATTATGAATTCTTATAATTTAACTAC
TAATAACGGTGCCAAAACTTTAAATGTTACAGATCATTATGGAATTGAAGTTGGAAAACCAGCTAATTGTTTAATTTTTA
ACACTGATAATTTTTATAATGAACTTAACGAACGGAAAGAATTATTGTATTCGATTCACAATGGAAAGATCATCGTTAAA
ACTGAACCAGCTGAAATAAAAACCAACTTTTAA

Upstream 100 bases:

>100_bases
TTGGACTTTGTTCAAACCTATACTGGGGCAACGTTCATTGTAATGATTATTATTGGAATTTTATATTGGCTAATTATGCA
GTTTGAAAAGAGGAACAGCA

Downstream 100 bases:

>100_bases
TTAAGTGGTGCCCGCTAACCAGGCTTTTTGTTAGGGACACCATTTTTTTTATGAGATAATTTAAATATTAAATAAGCGTA
AAGAAGTTGAGAAGATGAGA

Product: dihydroorotase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MLIKNVHIENDPEVKDVRIENGIFKAIGKNLEASDDEVIDANGKLLLPPFIDSHVHLDATLTAGDPEWNETGTLFDGIRI
WSERKQTLTKKETKERAIQTLKNQASHGIQFVRSHVDTTDPSFTALEALLEVKDEVKDFMELQLVAFPQEGILSFKNGKN
LIKQAVEMGVDVIGAIPHFEFNRDYGVDSLKYIVELAEKYDKLIDVHCDEIDDPNSRHLEVLATLAYESGLKNKVTASHT
TAMGSYNDAYVYKLMRLLEMSNINMVCNPLINMHLGGRFDTYPKRRGLTRVKELLENNVNVSFGEDDIKDPWYPMGDGNM
LDSIHMGIHATQLMGYSQIMNSYNLTTNNGAKTLNVTDHYGIEVGKPANCLIFNTDNFYNELNERKELLYSIHNGKIIVK
TEPAEIKTNF

Sequences:

>Translated_410_residues
MLIKNVHIENDPEVKDVRIENGIFKAIGKNLEASDDEVIDANGKLLLPPFIDSHVHLDATLTAGDPEWNETGTLFDGIRI
WSERKQTLTKKETKERAIQTLKNQASHGIQFVRSHVDTTDPSFTALEALLEVKDEVKDFMELQLVAFPQEGILSFKNGKN
LIKQAVEMGVDVIGAIPHFEFNRDYGVDSLKYIVELAEKYDKLIDVHCDEIDDPNSRHLEVLATLAYESGLKNKVTASHT
TAMGSYNDAYVYKLMRLLEMSNINMVCNPLINMHLGGRFDTYPKRRGLTRVKELLENNVNVSFGEDDIKDPWYPMGDGNM
LDSIHMGIHATQLMGYSQIMNSYNLTTNNGAKTLNVTDHYGIEVGKPANCLIFNTDNFYNELNERKELLYSIHNGKIIVK
TEPAEIKTNF
>Mature_410_residues
MLIKNVHIENDPEVKDVRIENGIFKAIGKNLEASDDEVIDANGKLLLPPFIDSHVHLDATLTAGDPEWNETGTLFDGIRI
WSERKQTLTKKETKERAIQTLKNQASHGIQFVRSHVDTTDPSFTALEALLEVKDEVKDFMELQLVAFPQEGILSFKNGKN
LIKQAVEMGVDVIGAIPHFEFNRDYGVDSLKYIVELAEKYDKLIDVHCDEIDDPNSRHLEVLATLAYESGLKNKVTASHT
TAMGSYNDAYVYKLMRLLEMSNINMVCNPLINMHLGGRFDTYPKRRGLTRVKELLENNVNVSFGEDDIKDPWYPMGDGNM
LDSIHMGIHATQLMGYSQIMNSYNLTTNNGAKTLNVTDHYGIEVGKPANCLIFNTDNFYNELNERKELLYSIHNGKIIVK
TEPAEIKTNF

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=405, Percent_Identity=53.0864197530864, Blast_Score=464, Evalue=1e-132,
Organism=Escherichia coli, GI1786517, Length=331, Percent_Identity=25.9818731117825, Blast_Score=95, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 46383; Mature: 46383

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIKNVHIENDPEVKDVRIENGIFKAIGKNLEASDDEVIDANGKLLLPPFIDSHVHLDAT
CCEEEECCCCCCCCEEEEECCCHHHHHCCCCCCCCCCEEECCCCEEECCCCCCCEEEEEE
LTAGDPEWNETGTLFDGIRIWSERKQTLTKKETKERAIQTLKNQASHGIQFVRSHVDTTD
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PSFTALEALLEVKDEVKDFMELQLVAFPQEGILSFKNGKNLIKQAVEMGVDVIGAIPHFE
CHHHHHHHHHHHHHHHHHHHHHHHEEECHHHCEEECCCHHHHHHHHHHCHHHHCCCCCCC
FNRDYGVDSLKYIVELAEKYDKLIDVHCDEIDDPNSRHLEVLATLAYESGLKNKVTASHT
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHH
TAMGSYNDAYVYKLMRLLEMSNINMVCNPLINMHLGGRFDTYPKRRGLTRVKELLENNVN
HCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHCCHHHHHHHHHCCCC
VSFGEDDIKDPWYPMGDGNMLDSIHMGIHATQLMGYSQIMNSYNLTTNNGAKTLNVTDHY
EEECCCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHCCCCEECCCCEEEEECCCC
GIEVGKPANCLIFNTDNFYNELNERKELLYSIHNGKIIVKTEPAEIKTNF
CEEECCCCCEEEECCHHHHHHHHHHHHHHHEECCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MLIKNVHIENDPEVKDVRIENGIFKAIGKNLEASDDEVIDANGKLLLPPFIDSHVHLDAT
CCEEEECCCCCCCCEEEEECCCHHHHHCCCCCCCCCCEEECCCCEEECCCCCCCEEEEEE
LTAGDPEWNETGTLFDGIRIWSERKQTLTKKETKERAIQTLKNQASHGIQFVRSHVDTTD
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PSFTALEALLEVKDEVKDFMELQLVAFPQEGILSFKNGKNLIKQAVEMGVDVIGAIPHFE
CHHHHHHHHHHHHHHHHHHHHHHHEEECHHHCEEECCCHHHHHHHHHHCHHHHCCCCCCC
FNRDYGVDSLKYIVELAEKYDKLIDVHCDEIDDPNSRHLEVLATLAYESGLKNKVTASHT
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHH
TAMGSYNDAYVYKLMRLLEMSNINMVCNPLINMHLGGRFDTYPKRRGLTRVKELLENNVN
HCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHCCHHHHHHHHHCCCC
VSFGEDDIKDPWYPMGDGNMLDSIHMGIHATQLMGYSQIMNSYNLTTNNGAKTLNVTDHY
EEECCCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHCCCCEECCCCEEEEECCCC
GIEVGKPANCLIFNTDNFYNELNERKELLYSIHNGKIIVKTEPAEIKTNF
CEEECCCCCEEEECCHHHHHHHHHHHHHHHEECCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]