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The map label for this gene is opuBB [H]

Identifier: 116492046

GI number: 116492046

Start: 285855

End: 287384

Strand: Direct

Name: opuBB [H]

Synonym: PEPE_0242

Alternate gene names: 116492046

Gene position: 285855-287384 (Clockwise)

Preceding gene: 116492045

Following gene: 116492047

Centisome position: 15.6

GC content: 37.52

Gene sequence:

>1530_bases
ATGAGAGCATTAATACAAACTTTTGCTGAACAAAAAGGTGAGTTAGGACAGGCGCTACTTCAGCATATTGGAATTTCAGT
TCTATCATTATTAATTGCGATTTTAATTGCGATGCCATTAGCAATTTGGGCTACCCATCATCGCAAAGTTGCAGAATTAT
TATTACAAGTCACGGGAGTTTTACAAACAATCCCTTCTTTAGCACTGCTGGGGCTATTGATTCCTTTAGTGGGGATTGGC
AGTGTACCCGCCGTAATTGCATTGGTAATTTACGCTTTGTTACCAATTTTTCAAAGCACATATGTGGGAATTACAGAAAT
TGATCCTTCCTTAGAGGAAGCTGCGGACGCTTTTGGAATGCGTCGTTCACAAAAACTTTTCCGAGTTGAATTACCAACAG
CGATGCCAGTCATTATTTCTGGAATTCGAACCGGACTAGTATTGATTATTGGAACGGCAACGCTAGCAGCTTTAATTGGA
GCAGGGGGCTTGGGAAATTTCATTCTGCTCGGGATCAACCGGAATGACCCACAACTAATTTTAGTTGGGGCAATTAGTTC
AGCCCTTTTAGCGATTATATTAAGTGCACTCATCAGCGTCGTTCAGCGTTTATCAATTAAGAAGATGCTTATCACCTTAG
CAGTATTAGTGATCGGGGCAGCTGGGATTTCTATCACGCGATTGGTAATGCCTAAAACTGAAACCATTACGATTGCCGGA
AAATTAGGAGCAGAACCGGATATTCTTATTAATATGTATAAGGATTTAATTGAGCAAGAAAGTCCACGAACTAAAGTGGT
ATTGAAACAAAATTTTGGTGAAACCACCTTTTTATTCAACGCTTTAAAATCAAATAAAATTGATATTTATCCTGAATTTA
CAGGAACGGTTTTAGAAACATTGGTGAAGAAAGCCCCTACTCAAAAAACGAGTGCGCATCAAACTTACTTAGATGCCCAA
CGATTATTGAAACAACAGTTCCAAATGGATTACCTGCAACCGATGAAATATCAAAATACGAATGCCCTTGTGGTTAAAAA
GGATTTTGCCAAGAAAAATGATTTAAAAACAATCTCAGATTTAAAAAATATTGAAAATCAGTTAAAAGGTGGCATGACCT
TAGAGTTTATTCATCGTAAAGATGGTTGGGTAGGAATTAAAAAGGCTTACGAATTAGATTTTCCAGTTCGTTCAATGCAG
GCTTCCTTACGCTATTCCGCCATTAAAAACGGACAGATTAATGTTGCTGATGCTTATTCTACCGATAGTCAAATAAAGCA
ATTGAATTTAACGACTTTAAAAGATGATCAACATGTTTTCCCTCCATATCAAGGGGCGCCCTTAATGAAAACGAGCTTTG
CCAATAAACATCCGCAAGTTGTCAAAGCACTTAATCGGTTAGCCGGTAAAATTTCAGAATCGGAAATGCAAGAAATGAAT
TATGAAGTTAATGTACAAAAGAAATCAGCTGATGTAGTGGCTCATCAATACTTAGTTAAAAAAGGTTTGTTGAAAGGAGA
CGGAAAATAG

Upstream 100 bases:

>100_bases
TTTTAATTAAGTGGTGCCCGCTAACCAGGCTTTTTGTTAGGGACACCATTTTTTTTATGAGATAATTTAAATATTAAATA
AGCGTAAAGAAGTTGAGAAG

Downstream 100 bases:

>100_bases
TGGCTAAAACAATGATCGAATTTCAACATGTGAAAAAGGATTTTGGAAATCATAGCGTAATTAAAGATATTAGTTTCGAA
GTTCAAGAAGGTGAAATTTT

Product: ABC-type proline/glycine betaine transport system, permease and substrate binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MRALIQTFAEQKGELGQALLQHIGISVLSLLIAILIAMPLAIWATHHRKVAELLLQVTGVLQTIPSLALLGLLIPLVGIG
SVPAVIALVIYALLPIFQSTYVGITEIDPSLEEAADAFGMRRSQKLFRVELPTAMPVIISGIRTGLVLIIGTATLAALIG
AGGLGNFILLGINRNDPQLILVGAISSALLAIILSALISVVQRLSIKKMLITLAVLVIGAAGISITRLVMPKTETITIAG
KLGAEPDILINMYKDLIEQESPRTKVVLKQNFGETTFLFNALKSNKIDIYPEFTGTVLETLVKKAPTQKTSAHQTYLDAQ
RLLKQQFQMDYLQPMKYQNTNALVVKKDFAKKNDLKTISDLKNIENQLKGGMTLEFIHRKDGWVGIKKAYELDFPVRSMQ
ASLRYSAIKNGQINVADAYSTDSQIKQLNLTTLKDDQHVFPPYQGAPLMKTSFANKHPQVVKALNRLAGKISESEMQEMN
YEVNVQKKSADVVAHQYLVKKGLLKGDGK

Sequences:

>Translated_509_residues
MRALIQTFAEQKGELGQALLQHIGISVLSLLIAILIAMPLAIWATHHRKVAELLLQVTGVLQTIPSLALLGLLIPLVGIG
SVPAVIALVIYALLPIFQSTYVGITEIDPSLEEAADAFGMRRSQKLFRVELPTAMPVIISGIRTGLVLIIGTATLAALIG
AGGLGNFILLGINRNDPQLILVGAISSALLAIILSALISVVQRLSIKKMLITLAVLVIGAAGISITRLVMPKTETITIAG
KLGAEPDILINMYKDLIEQESPRTKVVLKQNFGETTFLFNALKSNKIDIYPEFTGTVLETLVKKAPTQKTSAHQTYLDAQ
RLLKQQFQMDYLQPMKYQNTNALVVKKDFAKKNDLKTISDLKNIENQLKGGMTLEFIHRKDGWVGIKKAYELDFPVRSMQ
ASLRYSAIKNGQINVADAYSTDSQIKQLNLTTLKDDQHVFPPYQGAPLMKTSFANKHPQVVKALNRLAGKISESEMQEMN
YEVNVQKKSADVVAHQYLVKKGLLKGDGK
>Mature_509_residues
MRALIQTFAEQKGELGQALLQHIGISVLSLLIAILIAMPLAIWATHHRKVAELLLQVTGVLQTIPSLALLGLLIPLVGIG
SVPAVIALVIYALLPIFQSTYVGITEIDPSLEEAADAFGMRRSQKLFRVELPTAMPVIISGIRTGLVLIIGTATLAALIG
AGGLGNFILLGINRNDPQLILVGAISSALLAIILSALISVVQRLSIKKMLITLAVLVIGAAGISITRLVMPKTETITIAG
KLGAEPDILINMYKDLIEQESPRTKVVLKQNFGETTFLFNALKSNKIDIYPEFTGTVLETLVKKAPTQKTSAHQTYLDAQ
RLLKQQFQMDYLQPMKYQNTNALVVKKDFAKKNDLKTISDLKNIENQLKGGMTLEFIHRKDGWVGIKKAYELDFPVRSMQ
ASLRYSAIKNGQINVADAYSTDSQIKQLNLTTLKDDQHVFPPYQGAPLMKTSFANKHPQVVKALNRLAGKISESEMQEMN
YEVNVQKKSADVVAHQYLVKKGLLKGDGK

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1732

COG function: function code M; Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788451, Length=223, Percent_Identity=34.9775784753363, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788449, Length=192, Percent_Identity=38.5416666666667, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789033, Length=173, Percent_Identity=38.728323699422, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1788452, Length=281, Percent_Identity=27.7580071174377, Blast_Score=108, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 55735; Mature: 55735

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALIQTFAEQKGELGQALLQHIGISVLSLLIAILIAMPLAIWATHHRKVAELLLQVTGV
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQTIPSLALLGLLIPLVGIGSVPAVIALVIYALLPIFQSTYVGITEIDPSLEEAADAFGM
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCC
RRSQKLFRVELPTAMPVIISGIRTGLVLIIGTATLAALIGAGGLGNFILLGINRNDPQLI
HHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEE
LVGAISSALLAIILSALISVVQRLSIKKMLITLAVLVIGAAGISITRLVMPKTETITIAG
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEE
KLGAEPDILINMYKDLIEQESPRTKVVLKQNFGETTFLFNALKSNKIDIYPEFTGTVLET
CCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEECCHHHHHHHH
LVKKAPTQKTSAHQTYLDAQRLLKQQFQMDYLQPMKYQNTNALVVKKDFAKKNDLKTISD
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHH
LKNIENQLKGGMTLEFIHRKDGWVGIKKAYELDFPVRSMQASLRYSAIKNGQINVADAYS
HHHHHHHHCCCCEEEEEECCCCCEEECHHEECCCCHHHHHHHHHHHHHCCCCEEEEECCC
TDSQIKQLNLTTLKDDQHVFPPYQGAPLMKTSFANKHPQVVKALNRLAGKISESEMQEMN
CHHHHHHCCCEEECCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHCC
YEVNVQKKSADVVAHQYLVKKGLLKGDGK
CEEEEEHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRALIQTFAEQKGELGQALLQHIGISVLSLLIAILIAMPLAIWATHHRKVAELLLQVTGV
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQTIPSLALLGLLIPLVGIGSVPAVIALVIYALLPIFQSTYVGITEIDPSLEEAADAFGM
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCC
RRSQKLFRVELPTAMPVIISGIRTGLVLIIGTATLAALIGAGGLGNFILLGINRNDPQLI
HHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEE
LVGAISSALLAIILSALISVVQRLSIKKMLITLAVLVIGAAGISITRLVMPKTETITIAG
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEE
KLGAEPDILINMYKDLIEQESPRTKVVLKQNFGETTFLFNALKSNKIDIYPEFTGTVLET
CCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEECCHHHHHHHH
LVKKAPTQKTSAHQTYLDAQRLLKQQFQMDYLQPMKYQNTNALVVKKDFAKKNDLKTISD
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHH
LKNIENQLKGGMTLEFIHRKDGWVGIKKAYELDFPVRSMQASLRYSAIKNGQINVADAYS
HHHHHHHHCCCCEEEEEECCCCCEEECHHEECCCCHHHHHHHHHHHHHCCCCEEEEECCC
TDSQIKQLNLTTLKDDQHVFPPYQGAPLMKTSFANKHPQVVKALNRLAGKISESEMQEMN
CHHHHHHCCCEEECCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHCC
YEVNVQKKSADVVAHQYLVKKGLLKGDGK
CEEEEEHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592481; 10216873; 9384377 [H]