Click here to switch to the map view.

The map label for this gene is htpG

Identifier: 116515224

GI number: 116515224

Start: 343540

End: 345414

Strand: Direct

Name: htpG

Synonym: BCc_302

Alternate gene names: 116515224

Gene position: 343540-345414 (Clockwise)

Preceding gene: 116515223

Following gene: 116515225

Centisome position: 82.51

GC content: 20.8

Gene sequence:

>1875_bases
ATGAATAATAAAAATAAAATAACACATACATTTCAATCAGAAGTAAAAGAATTACTACATCTAATGATTCATTCTTTATA
TTCAAATAAAGAAATATTTTTAAGAGAATTAATATCTAATGCATCAGATGCAATAGAAAAAATAAGATTTGAAAAACTAT
ATAGTTTAAAAAAATATAGAGAAAATTTATATACACCTAAAATAAAAATTTCCATTAAAAAAGATGAAAAAAAAATTATT
ATTTCTGATAATGGTATAGGTATGACATATAAGGAAGTAATAAAAAATTTAGGAACAATTGCAAAATCAGGAACAAAATC
ATTTTTAAATAAAATTCAAAATATTGAAAAAAAAGAAAAAAATGATTTTATCGGACAATTTGGAGTAGGATTTTATTCAT
CTTTTATTGTTTCCAACTCTGTTTCTGTTTATACAAGACATGCAAAAGAAAAAAAAAACATTGGAACACTTTGGATATCA
GAAGGTAAAGGAAAATATTCTGTAGAAAAAATTTCTAAAGAAGAACATGGAACAATAGTAGAATTATCATTAAAATCTTC
TGAAAAAGAATTTTTAGAAATTTGGAAAATAAAAAATATTATAAAAAAATATTCAGATCATATTTCCATACCAATAGAAA
TAGAAAACTACGACGAAAAAACAAAAACAATTTCTTGGGAAAAAATTAACAAAGCACAAGCATTATGGACAATTAATAAA
AATAATATTACTAAAAAAAAATATCAAGATTTTTATAAATATCTTACTAATGATTCAGAAAAACCATTACTTTGGAGTCA
TAATAAAGTTGAAGGAACACAAGAATATATTAATTTATTATATATTCCTAAAAAAGCAACATGGGATATTTGGCATCAAG
AAAACAAACATGGTTTAAAGTTGTATGTTAAACATGTTTTTATTATGGATGAAGCAACACAATTTCTTCCAAATTATCTA
CGTTTTGTAAAAGGAATTATTGATTCCCAGGATCTTCCGTTAAATATTTCTAGAGAAATATTACAAGATAGCTCAATTAC
TCATATTTTACGAAAATCATTAACTAAACGTATTTTAAATATACTAAATAATTTATCAGAAAATAATATTAAAAAATATC
AAAAATTTTGGAATGTGTTCGGAATAATTATTAAAGAAGGAATAGCTGAAGATTCTGAAAATAAAACTATATTATCTAAT
TTATTACGTTTTTCTTCTATAAAAAAAGGAAACATAGAACAAACATTATCTTTAAATGAATATATAAAAAACATGAAAAA
AAATCAGAAAAAAATATATTTCATTACTTCAGATAGTTATAAATCAGCTTTAAATAGTCCGAATTTAGAAATATTTAAAG
AAAACGATATTGATGTATTAATATTATCTGAAAAAATTGATGAATGGATGATGAATTATTTAACTGAATTTAATAATATA
AAATTTCAATCAGTAAGTAAATTAGATGATACTATAGATAGTCTTTTATTAAAAAAAAATGTTTCTAATGAAAAAAACAC
ATTTAATGAATTTATTGAAAAAACAAAAAAAATATTGAAAAATAAAGTTAAAGATGTAAAAATTACATATCGTTTAAAAA
ATACACCAGCTATAGTATTAACTGATACCAATGATATGAGCACACAAATGGCAAAAATATTTAGTGCTGCTGGACAACCA
ATTCCAAAAATAAAATATATTTTAGAAATTAATCCATTACATCCATTAATAAAAAAAATAGAAAAAATAAAAAATGAAAA
AGATTTTTCTAATTGGATAAAAATAATATTTGATCAATCAATTCTATCAGAAAAAGGTAGTTTAGAAAATCCACATAAAT
TTATTCAAAGAATAAACAATTTCTTTATATCATAA

Upstream 100 bases:

>100_bases
CAAATAATATAAAACATATGACAAAAAATCAGATATAATATATAAAAATTAAATAATTTATAAAACAAATTATTTATCTA
TATTTTAATAGGTATTCAAT

Downstream 100 bases:

>100_bases
AAATTTTATTTATAAAAATATCACTTATTTAAAATTGATGTATAATAAAATAATTTTTATAAAGGAAAATTTTTTATAAT
GCGTATTATTATGATAGGTC

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 624; Mature: 624

Protein sequence:

>624_residues
MNNKNKITHTFQSEVKELLHLMIHSLYSNKEIFLRELISNASDAIEKIRFEKLYSLKKYRENLYTPKIKISIKKDEKKII
ISDNGIGMTYKEVIKNLGTIAKSGTKSFLNKIQNIEKKEKNDFIGQFGVGFYSSFIVSNSVSVYTRHAKEKKNIGTLWIS
EGKGKYSVEKISKEEHGTIVELSLKSSEKEFLEIWKIKNIIKKYSDHISIPIEIENYDEKTKTISWEKINKAQALWTINK
NNITKKKYQDFYKYLTNDSEKPLLWSHNKVEGTQEYINLLYIPKKATWDIWHQENKHGLKLYVKHVFIMDEATQFLPNYL
RFVKGIIDSQDLPLNISREILQDSSITHILRKSLTKRILNILNNLSENNIKKYQKFWNVFGIIIKEGIAEDSENKTILSN
LLRFSSIKKGNIEQTLSLNEYIKNMKKNQKKIYFITSDSYKSALNSPNLEIFKENDIDVLILSEKIDEWMMNYLTEFNNI
KFQSVSKLDDTIDSLLLKKNVSNEKNTFNEFIEKTKKILKNKVKDVKITYRLKNTPAIVLTDTNDMSTQMAKIFSAAGQP
IPKIKYILEINPLHPLIKKIEKIKNEKDFSNWIKIIFDQSILSEKGSLENPHKFIQRINNFFIS

Sequences:

>Translated_624_residues
MNNKNKITHTFQSEVKELLHLMIHSLYSNKEIFLRELISNASDAIEKIRFEKLYSLKKYRENLYTPKIKISIKKDEKKII
ISDNGIGMTYKEVIKNLGTIAKSGTKSFLNKIQNIEKKEKNDFIGQFGVGFYSSFIVSNSVSVYTRHAKEKKNIGTLWIS
EGKGKYSVEKISKEEHGTIVELSLKSSEKEFLEIWKIKNIIKKYSDHISIPIEIENYDEKTKTISWEKINKAQALWTINK
NNITKKKYQDFYKYLTNDSEKPLLWSHNKVEGTQEYINLLYIPKKATWDIWHQENKHGLKLYVKHVFIMDEATQFLPNYL
RFVKGIIDSQDLPLNISREILQDSSITHILRKSLTKRILNILNNLSENNIKKYQKFWNVFGIIIKEGIAEDSENKTILSN
LLRFSSIKKGNIEQTLSLNEYIKNMKKNQKKIYFITSDSYKSALNSPNLEIFKENDIDVLILSEKIDEWMMNYLTEFNNI
KFQSVSKLDDTIDSLLLKKNVSNEKNTFNEFIEKTKKILKNKVKDVKITYRLKNTPAIVLTDTNDMSTQMAKIFSAAGQP
IPKIKYILEINPLHPLIKKIEKIKNEKDFSNWIKIIFDQSILSEKGSLENPHKFIQRINNFFIS
>Mature_624_residues
MNNKNKITHTFQSEVKELLHLMIHSLYSNKEIFLRELISNASDAIEKIRFEKLYSLKKYRENLYTPKIKISIKKDEKKII
ISDNGIGMTYKEVIKNLGTIAKSGTKSFLNKIQNIEKKEKNDFIGQFGVGFYSSFIVSNSVSVYTRHAKEKKNIGTLWIS
EGKGKYSVEKISKEEHGTIVELSLKSSEKEFLEIWKIKNIIKKYSDHISIPIEIENYDEKTKTISWEKINKAQALWTINK
NNITKKKYQDFYKYLTNDSEKPLLWSHNKVEGTQEYINLLYIPKKATWDIWHQENKHGLKLYVKHVFIMDEATQFLPNYL
RFVKGIIDSQDLPLNISREILQDSSITHILRKSLTKRILNILNNLSENNIKKYQKFWNVFGIIIKEGIAEDSENKTILSN
LLRFSSIKKGNIEQTLSLNEYIKNMKKNQKKIYFITSDSYKSALNSPNLEIFKENDIDVLILSEKIDEWMMNYLTEFNNI
KFQSVSKLDDTIDSLLLKKNVSNEKNTFNEFIEKTKKILKNKVKDVKITYRLKNTPAIVLTDTNDMSTQMAKIFSAAGQP
IPKIKYILEINPLHPLIKKIEKIKNEKDFSNWIKIIFDQSILSEKGSLENPHKFIQRINNFFIS

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI20149594, Length=677, Percent_Identity=36.3367799113737, Blast_Score=382, Evalue=1e-106,
Organism=Homo sapiens, GI155722983, Length=640, Percent_Identity=33.4375, Blast_Score=356, Evalue=3e-98,
Organism=Homo sapiens, GI4507677, Length=678, Percent_Identity=32.5958702064897, Blast_Score=331, Evalue=1e-90,
Organism=Homo sapiens, GI154146191, Length=407, Percent_Identity=37.3464373464373, Blast_Score=246, Evalue=4e-65,
Organism=Homo sapiens, GI153792590, Length=407, Percent_Identity=37.3464373464373, Blast_Score=244, Evalue=2e-64,
Organism=Escherichia coli, GI1786679, Length=625, Percent_Identity=54.08, Blast_Score=734, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=671, Percent_Identity=35.618479880775, Blast_Score=374, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17542208, Length=667, Percent_Identity=33.5832083958021, Blast_Score=342, Evalue=3e-94,
Organism=Caenorhabditis elegans, GI115535205, Length=646, Percent_Identity=31.733746130031, Blast_Score=289, Evalue=4e-78,
Organism=Caenorhabditis elegans, GI115535167, Length=431, Percent_Identity=35.9628770301624, Blast_Score=252, Evalue=4e-67,
Organism=Saccharomyces cerevisiae, GI6323840, Length=684, Percent_Identity=35.0877192982456, Blast_Score=388, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6325016, Length=410, Percent_Identity=34.6341463414634, Blast_Score=251, Evalue=2e-67,
Organism=Drosophila melanogaster, GI17647529, Length=684, Percent_Identity=34.7953216374269, Blast_Score=377, Evalue=1e-104,
Organism=Drosophila melanogaster, GI21357739, Length=638, Percent_Identity=36.833855799373, Blast_Score=357, Evalue=2e-98,
Organism=Drosophila melanogaster, GI24586016, Length=645, Percent_Identity=34.1085271317829, Blast_Score=342, Evalue=3e-94,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_BUCCC (Q057D9)

Other databases:

- EMBL:   CP000263
- RefSeq:   YP_802853.1
- ProteinModelPortal:   Q057D9
- STRING:   Q057D9
- EnsemblBacteria:   EBBUCT00000001441
- GeneID:   4440909
- GenomeReviews:   CP000263_GR
- KEGG:   bcc:BCc_302
- eggNOG:   COG0326
- GeneTree:   EBGT00050000008181
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- ProtClustDB:   PRK05218
- BioCyc:   BAPH372461:BCC_302-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 73126; Mature: 73126

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKNKITHTFQSEVKELLHLMIHSLYSNKEIFLRELISNASDAIEKIRFEKLYSLKKYR
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENLYTPKIKISIKKDEKKIIISDNGIGMTYKEVIKNLGTIAKSGTKSFLNKIQNIEKKEK
HHHCCCEEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
NDFIGQFGVGFYSSFIVSNSVSVYTRHAKEKKNIGTLWISEGKGKYSVEKISKEEHGTIV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHCCCCCCCEE
ELSLKSSEKEFLEIWKIKNIIKKYSDHISIPIEIENYDEKTKTISWEKINKAQALWTINK
EEEECCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHCCCHHHHCCCCEEEEECC
NNITKKKYQDFYKYLTNDSEKPLLWSHNKVEGTQEYINLLYIPKKATWDIWHQENKHGLK
CCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHEEEEECCCCCCCHHHCCCCCCCCE
LYVKHVFIMDEATQFLPNYLRFVKGIIDSQDLPLNISREILQDSSITHILRKSLTKRILN
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHH
ILNNLSENNIKKYQKFWNVFGIIIKEGIAEDSENKTILSNLLRFSSIKKGNIEQTLSLNE
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHH
YIKNMKKNQKKIYFITSDSYKSALNSPNLEIFKENDIDVLILSEKIDEWMMNYLTEFNNI
HHHHHHCCCCEEEEEECCHHHHHCCCCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHCCC
KFQSVSKLDDTIDSLLLKKNVSNEKNTFNEFIEKTKKILKNKVKDVKITYRLKNTPAIVL
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEE
TDTNDMSTQMAKIFSAAGQPIPKIKYILEINPLHPLIKKIEKIKNEKDFSNWIKIIFDQS
ECCCCHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ILSEKGSLENPHKFIQRINNFFIS
HHHCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNNKNKITHTFQSEVKELLHLMIHSLYSNKEIFLRELISNASDAIEKIRFEKLYSLKKYR
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENLYTPKIKISIKKDEKKIIISDNGIGMTYKEVIKNLGTIAKSGTKSFLNKIQNIEKKEK
HHHCCCEEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
NDFIGQFGVGFYSSFIVSNSVSVYTRHAKEKKNIGTLWISEGKGKYSVEKISKEEHGTIV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHCCCCCCCEE
ELSLKSSEKEFLEIWKIKNIIKKYSDHISIPIEIENYDEKTKTISWEKINKAQALWTINK
EEEECCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHCCCHHHHCCCCEEEEECC
NNITKKKYQDFYKYLTNDSEKPLLWSHNKVEGTQEYINLLYIPKKATWDIWHQENKHGLK
CCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHEEEEECCCCCCCHHHCCCCCCCCE
LYVKHVFIMDEATQFLPNYLRFVKGIIDSQDLPLNISREILQDSSITHILRKSLTKRILN
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHH
ILNNLSENNIKKYQKFWNVFGIIIKEGIAEDSENKTILSNLLRFSSIKKGNIEQTLSLNE
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHH
YIKNMKKNQKKIYFITSDSYKSALNSPNLEIFKENDIDVLILSEKIDEWMMNYLTEFNNI
HHHHHHCCCCEEEEEECCHHHHHCCCCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHCCC
KFQSVSKLDDTIDSLLLKKNVSNEKNTFNEFIEKTKKILKNKVKDVKITYRLKNTPAIVL
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEE
TDTNDMSTQMAKIFSAAGQPIPKIKYILEINPLHPLIKKIEKIKNEKDFSNWIKIIFDQS
ECCCCHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ILSEKGSLENPHKFIQRINNFFIS
HHHCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA