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The map label for this gene is asd [H]

Identifier: 116515203

GI number: 116515203

Start: 311592

End: 312707

Strand: Reverse

Name: asd [H]

Synonym: BCc_277

Alternate gene names: 116515203

Gene position: 312707-311592 (Counterclockwise)

Preceding gene: 116515211

Following gene: 116515194

Centisome position: 75.1

GC content: 23.57

Gene sequence:

>1116_bases
ATGAAAAAATTAGTAGGTTTTGTAGGGTGGAGAGGTATGGTGGGATCAGTTTTATTAAATCGTTTACGTAAAAATAATGA
TTTTAAGAATTTTAATTCTGTATTTTTAACTACATCTCAATTAAATTTTAATTCTCCTGATATTAAAAATTGTATTTCAA
ATAATTTAAAAGATGCATATAATATTAAATATTTAATGTCTTTAGACATTATAGTTTCATGTCAAGGGCAAGAATATACA
AAAAAAGTTTATACTAAATTAAAAAATATGCACTGGAAAGGATATTGGATTGATGCATCTTCTTTTTTAAGAATGAAAGA
AGATGCAATTATTGTCTTAGATCCTATAAATTATAATGCAATAAAATTAGGAATAAATAAAGGAATAAAAACTTTTGTAG
GAGGTAATTGTACCGTTAGTTTAATGTTACTTGCTTTAGGTGGATTATTTACAAATAATCTTATTGAATGGATTTCTGTA
GCAACATATCAATCTATTTCTGGTAGTGGTTCTAAAAGCATGTTAGAATTACTAAATCAAATTGGTTATGTGTATAAAAA
TATTTCTTCTTATCTTTCTACTTCTACAAGTTCTATTCTTAAAATAGAAAAAAAAATTACTTTTTTATTAAATAGTAAAA
ATTGTCCTAAAAATTTTATGAAAGTTCCTTTATTAGGAAATGTATTTCCCTGGATTGATAGTTTAATGGAAAATGGACAA
ACAAAAGAAGAGTGGAAAGGTTTTGTTGAAACAAATAAAATTTTAAATTACAAGTATAATATACCTATTGATGGAATTTG
TGTAAGAGTTCCTACGTTACGTTGTCATAGTCAAGTATTTACAATAAAATTAAAAAAAGATATTTCTATAAAAGAAATTA
AATACTTACTATCTTCTCATAATTCATGGGTAAAAATAATTAAAAATAATATAGATCATACAATAAGTAAATTAAATCCT
TTACAAGTTACAAATACATTAAACATTCCTATTGGTCGTATTAAAAAATTAAATTTTGGAAAAAAATATTTATCTGCTTT
TTCTGTTGGTGATCAATTATTATGGGGTGCAGCTGAACCATTACGTCGTATTTTAAATATTTTGATATCTCAATAA

Upstream 100 bases:

>100_bases
AATAAAAATTAAATTATTATTATATATAATATAAATATTAAAAAAACTTATAAAATATTATTTTTTAATGAAATAAGTGC
TTTAGATAGAGAAAATAATG

Downstream 100 bases:

>100_bases
ATTTCTTAATATTTTTTCTTTTTTCCAATTTTTATATAGTATAAAAAAAATTTTTTTTTTATAGTAATTGATATTAATTT
ATGTTTCATAAATCTACAAA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MKKLVGFVGWRGMVGSVLLNRLRKNNDFKNFNSVFLTTSQLNFNSPDIKNCISNNLKDAYNIKYLMSLDIIVSCQGQEYT
KKVYTKLKNMHWKGYWIDASSFLRMKEDAIIVLDPINYNAIKLGINKGIKTFVGGNCTVSLMLLALGGLFTNNLIEWISV
ATYQSISGSGSKSMLELLNQIGYVYKNISSYLSTSTSSILKIEKKITFLLNSKNCPKNFMKVPLLGNVFPWIDSLMENGQ
TKEEWKGFVETNKILNYKYNIPIDGICVRVPTLRCHSQVFTIKLKKDISIKEIKYLLSSHNSWVKIIKNNIDHTISKLNP
LQVTNTLNIPIGRIKKLNFGKKYLSAFSVGDQLLWGAAEPLRRILNILISQ

Sequences:

>Translated_371_residues
MKKLVGFVGWRGMVGSVLLNRLRKNNDFKNFNSVFLTTSQLNFNSPDIKNCISNNLKDAYNIKYLMSLDIIVSCQGQEYT
KKVYTKLKNMHWKGYWIDASSFLRMKEDAIIVLDPINYNAIKLGINKGIKTFVGGNCTVSLMLLALGGLFTNNLIEWISV
ATYQSISGSGSKSMLELLNQIGYVYKNISSYLSTSTSSILKIEKKITFLLNSKNCPKNFMKVPLLGNVFPWIDSLMENGQ
TKEEWKGFVETNKILNYKYNIPIDGICVRVPTLRCHSQVFTIKLKKDISIKEIKYLLSSHNSWVKIIKNNIDHTISKLNP
LQVTNTLNIPIGRIKKLNFGKKYLSAFSVGDQLLWGAAEPLRRILNILISQ
>Mature_371_residues
MKKLVGFVGWRGMVGSVLLNRLRKNNDFKNFNSVFLTTSQLNFNSPDIKNCISNNLKDAYNIKYLMSLDIIVSCQGQEYT
KKVYTKLKNMHWKGYWIDASSFLRMKEDAIIVLDPINYNAIKLGINKGIKTFVGGNCTVSLMLLALGGLFTNNLIEWISV
ATYQSISGSGSKSMLELLNQIGYVYKNISSYLSTSTSSILKIEKKITFLLNSKNCPKNFMKVPLLGNVFPWIDSLMENGQ
TKEEWKGFVETNKILNYKYNIPIDGICVRVPTLRCHSQVFTIKLKKDISIKEIKYLLSSHNSWVKIIKNNIDHTISKLNP
LQVTNTLNIPIGRIKKLNFGKKYLSAFSVGDQLLWGAAEPLRRILNILISQ

Specific function: Second step in the common biosynthetic pathway leading from Asp to the cell wall precursor meso-diaminopimelate, to Lys, to Met, to Ile and to Thr. [C]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789841, Length=366, Percent_Identity=55.7377049180328, Blast_Score=460, Evalue=1e-131,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR011534
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 42162; Mature: 42162

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLVGFVGWRGMVGSVLLNRLRKNNDFKNFNSVFLTTSQLNFNSPDIKNCISNNLKDAY
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCHHHHHHHCCCCHHH
NIKYLMSLDIIVSCQGQEYTKKVYTKLKNMHWKGYWIDASSFLRMKEDAIIVLDPINYNA
CEEEEEEEEEEEEECCCHHHHHHHHHHHCCCCCEEEECHHHHHEECCCCEEEEECCCCCE
IKLGINKGIKTFVGGNCTVSLMLLALGGLFTNNLIEWISVATYQSISGSGSKSMLELLNQ
EEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IGYVYKNISSYLSTSTSSILKIEKKITFLLNSKNCPKNFMKVPLLGNVFPWIDSLMENGQ
HHHHHHHHHHHHHCCHHHHHHHHHHEEEEECCCCCCHHHHCCCCCCCHHHHHHHHHHCCC
TKEEWKGFVETNKILNYKYNIPIDGICVRVPTLRCHSQVFTIKLKKDISIKEIKYLLSSH
CHHHHHHHHHHCEEEEEEECCCCCCEEEEECCEEECCEEEEEEEECCCCHHHHHHHHHCC
NSWVKIIKNNIDHTISKLNPLQVTNTLNIPIGRIKKLNFGKKYLSAFSVGDQLLWGAAEP
CCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHEEECCCCHHHHHHHHCCHHHHHCCHHH
LRRILNILISQ
HHHHHHHHHCC
>Mature Secondary Structure
MKKLVGFVGWRGMVGSVLLNRLRKNNDFKNFNSVFLTTSQLNFNSPDIKNCISNNLKDAY
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCHHHHHHHCCCCHHH
NIKYLMSLDIIVSCQGQEYTKKVYTKLKNMHWKGYWIDASSFLRMKEDAIIVLDPINYNA
CEEEEEEEEEEEEECCCHHHHHHHHHHHCCCCCEEEECHHHHHEECCCCEEEEECCCCCE
IKLGINKGIKTFVGGNCTVSLMLLALGGLFTNNLIEWISVATYQSISGSGSKSMLELLNQ
EEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IGYVYKNISSYLSTSTSSILKIEKKITFLLNSKNCPKNFMKVPLLGNVFPWIDSLMENGQ
HHHHHHHHHHHHHCCHHHHHHHHHHEEEEECCCCCCHHHHCCCCCCCHHHHHHHHHHCCC
TKEEWKGFVETNKILNYKYNIPIDGICVRVPTLRCHSQVFTIKLKKDISIKEIKYLLSSH
CHHHHHHHHHHCEEEEEEECCCCCCEEEEECCEEECCEEEEEEEECCCCHHHHHHHHHCC
NSWVKIIKNNIDHTISKLNPLQVTNTLNIPIGRIKKLNFGKKYLSAFSVGDQLLWGAAEP
CCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHEEECCCCHHHHHHHHCCHHHHHCCHHH
LRRILNILISQ
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]