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The map label for this gene is lysA [H]

Identifier: 116515197

GI number: 116515197

Start: 304496

End: 305746

Strand: Direct

Name: lysA [H]

Synonym: BCc_271

Alternate gene names: 116515197

Gene position: 304496-305746 (Clockwise)

Preceding gene: 116515196

Following gene: 116515198

Centisome position: 73.13

GC content: 21.9

Gene sequence:

>1251_bases
ATGACACATATATATAATTTACAAAAAAAGATGCTTACAAGAAAAAATTTATTATTTTTAATAAAAAAATATAAAACTCC
AATATGGATATATAATTCAGAAATTATTAAAAAACAAATAAAAAAACTAAAAAAATTTGATATTATTAGATTTGCTCAAA
AATCTTGTTCTAACATTCATATTTTAAAATTAATGAGAAAAAAAAACATAAAAATTGATGCAGTTTCGTTAGGAGAAATA
GAACGAGCATTACTAGCTGGATTTAAACCAAAAAATAATAATATTGTTTTTACATCAGACATTATAGAAAATAAAGTCTT
AAAAAAAGTTATTAAATATAAAATACCAGTAAATGCTGGTTCTATTGATATGTTAAAAAAAATTGGAAAAAAATCATTGA
AACATCCAGTATGGATTAGAATTAATCCAAAATTTGGTGACGGACATCATATTAAAACAAATACTGGTGGAGAAAATAGC
AAACATGGGATATGGAATCCTAAAAAAGCTTTATCTGTTATAAAAAAATATAAATTAAATCTTATTGGATTACATATACA
TATAGGCTCCGGGATAAAAACAAAAAATTTACATAAAGTTTGTAATGCTATGAAAAAATATGCAATTAAATTAAAAACAA
AAATAAAATTTATATCTGCCGGAGGTGGAATTAGTATTCCATATAAATCTAAAGAAAAAGAAATTAACATAAAAGATTAT
TTTTCACAATGGGATAAAACAAAAAAAAAAATTTCTTCTATATTAAATTGTTCTATTCAATTAGAAATTGAACCTGGTCG
ATTTTTAACAGCTCAATCAGGAATTTTAATTGCTAAAGTATATGCAATAAAAAAAATGGGTAAAAACATTTTTGTATTAA
TAAATTCAGGATTTAATGATTTAATTCGACCTATTTTATATGGTAGTTACCATAAAATAACTGTATTTCATAAAAAAAAA
TCAAAGAAAAAAAGAAAAAAAATAAAAACTATCTTTGCTGAACCGTTATGTGAATCTGGTGATGTTTTTACAATAAAAAA
AAATGAAATTATTTTTCATAGAAAAATACCACAAGTTAAACTTGGTGATTATATTATTATACATGATACCGGAGCTTATG
GATCTTCTATGTCATCAAATTATAATAGTAGACCATTTATTCCAGAAATCTTATATAAAAAAAACAATTTTGTACAAATT
AGAAGACGCCAAACAATAAAAGAAATGTTATCATTAGAAACATTAATATAA

Upstream 100 bases:

>100_bases
ATTAAATTAAATTAAATAAATATTTTTATATATAAAATTTTTAAATAAAATATATTTATAAAAATTTTTAAAAAAATATT
TATATTTTAGGATTTTTAAT

Downstream 100 bases:

>100_bases
TAACTAAAAAAAATATAAATAAATATTATTTAAAAGTTAAAAATTATTTATGAAAAAAAACAAAAAAAAAAAAAAATATA
TATTTAAACTTGGGGATGTC

Product: diaminopimelate decarboxylase

Products: NA

Alternate protein names: DAP decarboxylase [H]

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MTHIYNLQKKMLTRKNLLFLIKKYKTPIWIYNSEIIKKQIKKLKKFDIIRFAQKSCSNIHILKLMRKKNIKIDAVSLGEI
ERALLAGFKPKNNNIVFTSDIIENKVLKKVIKYKIPVNAGSIDMLKKIGKKSLKHPVWIRINPKFGDGHHIKTNTGGENS
KHGIWNPKKALSVIKKYKLNLIGLHIHIGSGIKTKNLHKVCNAMKKYAIKLKTKIKFISAGGGISIPYKSKEKEINIKDY
FSQWDKTKKKISSILNCSIQLEIEPGRFLTAQSGILIAKVYAIKKMGKNIFVLINSGFNDLIRPILYGSYHKITVFHKKK
SKKKRKKIKTIFAEPLCESGDVFTIKKNEIIFHRKIPQVKLGDYIIIHDTGAYGSSMSSNYNSRPFIPEILYKKNNFVQI
RRRQTIKEMLSLETLI

Sequences:

>Translated_416_residues
MTHIYNLQKKMLTRKNLLFLIKKYKTPIWIYNSEIIKKQIKKLKKFDIIRFAQKSCSNIHILKLMRKKNIKIDAVSLGEI
ERALLAGFKPKNNNIVFTSDIIENKVLKKVIKYKIPVNAGSIDMLKKIGKKSLKHPVWIRINPKFGDGHHIKTNTGGENS
KHGIWNPKKALSVIKKYKLNLIGLHIHIGSGIKTKNLHKVCNAMKKYAIKLKTKIKFISAGGGISIPYKSKEKEINIKDY
FSQWDKTKKKISSILNCSIQLEIEPGRFLTAQSGILIAKVYAIKKMGKNIFVLINSGFNDLIRPILYGSYHKITVFHKKK
SKKKRKKIKTIFAEPLCESGDVFTIKKNEIIFHRKIPQVKLGDYIIIHDTGAYGSSMSSNYNSRPFIPEILYKKNNFVQI
RRRQTIKEMLSLETLI
>Mature_415_residues
THIYNLQKKMLTRKNLLFLIKKYKTPIWIYNSEIIKKQIKKLKKFDIIRFAQKSCSNIHILKLMRKKNIKIDAVSLGEIE
RALLAGFKPKNNNIVFTSDIIENKVLKKVIKYKIPVNAGSIDMLKKIGKKSLKHPVWIRINPKFGDGHHIKTNTGGENSK
HGIWNPKKALSVIKKYKLNLIGLHIHIGSGIKTKNLHKVCNAMKKYAIKLKTKIKFISAGGGISIPYKSKEKEINIKDYF
SQWDKTKKKISSILNCSIQLEIEPGRFLTAQSGILIAKVYAIKKMGKNIFVLINSGFNDLIRPILYGSYHKITVFHKKKS
KKKRKKIKTIFAEPLCESGDVFTIKKNEIIFHRKIPQVKLGDYIIIHDTGAYGSSMSSNYNSRPFIPEILYKKNNFVQIR
RRQTIKEMLSLETLI

Specific function: Lysine biosynthesis; last step. [C]

COG id: COG0019

COG function: function code E; Diaminopimelate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]

Homologues:

Organism=Escherichia coli, GI1789203, Length=400, Percent_Identity=51.5, Blast_Score=479, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002986
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.20 [H]

Molecular weight: Translated: 47972; Mature: 47841

Theoretical pI: Translated: 10.94; Mature: 10.94

Prosite motif: PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHIYNLQKKMLTRKNLLFLIKKYKTPIWIYNSEIIKKQIKKLKKFDIIRFAQKSCSNIH
CCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCH
ILKLMRKKNIKIDAVSLGEIERALLAGFKPKNNNIVFTSDIIENKVLKKVIKYKIPVNAG
HHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHEECCCCCC
SIDMLKKIGKKSLKHPVWIRINPKFGDGHHIKTNTGGENSKHGIWNPKKALSVIKKYKLN
CHHHHHHHHHHHCCCCEEEEEECCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCE
LIGLHIHIGSGIKTKNLHKVCNAMKKYAIKLKTKIKFISAGGGISIPYKSKEKEINIKDY
EEEEEEEECCCCCCHHHHHHHHHHHHHHEEEEEEEEEEECCCCEECCCCCCCCCCCHHHH
FSQWDKTKKKISSILNCSIQLEIEPGRFLTAQSGILIAKVYAIKKMGKNIFVLINSGFND
HHHHHHHHHHHHHHHCCEEEEEECCCEEEEECCCEEEHHHHHHHHCCCEEEEEEECCHHH
LIRPILYGSYHKITVFHKKKSKKKRKKIKTIFAEPLCESGDVFTIKKNEIIFHRKIPQVK
HHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEECCCCEE
LGDYIIIHDTGAYGSSMSSNYNSRPFIPEILYKKNNFVQIRRRQTIKEMLSLETLI
ECCEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
THIYNLQKKMLTRKNLLFLIKKYKTPIWIYNSEIIKKQIKKLKKFDIIRFAQKSCSNIH
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCH
ILKLMRKKNIKIDAVSLGEIERALLAGFKPKNNNIVFTSDIIENKVLKKVIKYKIPVNAG
HHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHEECCCCCC
SIDMLKKIGKKSLKHPVWIRINPKFGDGHHIKTNTGGENSKHGIWNPKKALSVIKKYKLN
CHHHHHHHHHHHCCCCEEEEEECCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCE
LIGLHIHIGSGIKTKNLHKVCNAMKKYAIKLKTKIKFISAGGGISIPYKSKEKEINIKDY
EEEEEEEECCCCCCHHHHHHHHHHHHHHEEEEEEEEEEECCCCEECCCCCCCCCCCHHHH
FSQWDKTKKKISSILNCSIQLEIEPGRFLTAQSGILIAKVYAIKKMGKNIFVLINSGFND
HHHHHHHHHHHHHHHCCEEEEEECCCEEEEECCCEEEHHHHHHHHCCCEEEEEEECCHHH
LIRPILYGSYHKITVFHKKKSKKKRKKIKTIFAEPLCESGDVFTIKKNEIIFHRKIPQVK
HHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEECCCCEE
LGDYIIIHDTGAYGSSMSSNYNSRPFIPEILYKKNNFVQIRRRQTIKEMLSLETLI
ECCEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]