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The map label for this gene is lysS

Identifier: 116515196

GI number: 116515196

Start: 302882

End: 304390

Strand: Direct

Name: lysS

Synonym: BCc_270

Alternate gene names: 116515196

Gene position: 302882-304390 (Clockwise)

Preceding gene: 116515195

Following gene: 116515197

Centisome position: 72.74

GC content: 18.09

Gene sequence:

>1509_bases
ATGTCAAAAACTTTAAAAATAATTCAAAAAAAAAAATCCTTAGAAAAAGAATTATATACAAGAAAAAAAAAACTAAAAAA
ATTAAAAAAATTAGGTTTTAATTTTCCAAATACTTTTCATTATATACATACAATTAAAGAAATAAAAAAATTATATAATA
ATTATACAAAAAAAGAATTAGAAAAAATTAACTATAAAACGAAAATTTCAGGAAGAATAGTAAATAAAAGAACTTTTGGT
AAAGCGTTATTCTTTGTTATACGAAATAATAATCATGACATTCAAATATATATTAAAAGTAATTATTTTCCAAAAAATTA
TTATCAAAAAAATATTCTTGAATTAGATTTAGGTGATATTATTGGGGTAAAAGGAAAAATATTTAAAACAAATACATGCG
AGTTATCAATTTTATGTAAAAAAATATATTTATTAACTAAATCTTTAAGATCTTTACCTGATAAATATTTTGGATTAAAA
AATCAAGAAATTAAATATAGAAAAAGATATTTAGATTTAATATCTAATAATAAAATTATTAAAATTTTTCAAAAAAGATC
ATTAATTATATCTAACATAAGATCTTTTATGAAACAAAAAAAATTCTTGGAAGTTGAAACTCCTATGTTACATCCTATCC
CAGGTGGAGCTAATGCAAAACCATTCATCACTTATCATAATTCATTAAACGAAAAAATGTATTTAAGAATAGCACCTGAA
TTATATCTTAAAAAATTAATTATTGGTGGTTTTAATAAAATATTTGAAATAAATAGAAATTTTAGAAATGAAGGTATATC
AACAAAACATAATCCAGAATTTACAATGATGGAAATTTATATGTCTTATAGTAATTATATTGATATAATGAATTTATTAG
AAGAATTATGTATTTTTTTAGTAAAAAAAATTTCTAAATCATTAATTATTATGTATAAATCAAAAAAAATAAATTTTAAA
AAACCTATAAAAAAAATGACAATGATTGAATCTATTTTAAAATTTAATAAAAATATTGATATATCTAATTTTAAAAATAT
AAAAAATATAAAAAAAACTGCAACAAATCTTAATATTAAAATTGATTCAAATGCATCTTTAGGAGAAATTACAAATTTAA
TTTTTGAAAAAACAACAGAAAAAAAAATTATTCAACCAACATTTATTACTGAGTATCCAATTGAAATTTCTCCATTAGCA
AAAGAAAAAAATAAATATTTTGCAGAAAGATTTGAATTTTTTATTGCAGGTTATGAAATAGCAAACGGTTTTTCTGAATT
AAATGATCCAGAAGAACAAAAAAAACGATTTAAATTACAAATATCTAAAAAAAATTATACAGATAAATCAAAAAATTTTT
CTTATGATAAAGATTATATTATTGCTTTAGAACACGGTTTACCTCCTACATCTGGATTAGGAGTAGGAATTGATAGATTG
ATTATGATTTTAACTAATCAAAAAACTATAAAAGATATTATTTTTTTTCCTTTATTAAAAAAAATTTAA

Upstream 100 bases:

>100_bases
AAGATATGAGAACTAAATTAGAAAGGAAAGATATTAATAATGTTTTAAATGGTGATATTCATGAATTCATTAAAAAAAGT
TTAAAAATGGGATTTTAAAT

Downstream 100 bases:

>100_bases
TATTAATTAAATTAAATTAAATAAATATTTTTATATATAAAATTTTTAAATAAAATATATTTATAAAAATTTTTAAAAAA
ATATTTATATTTTAGGATTT

Product: hypothetical protein

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MSKTLKIIQKKKSLEKELYTRKKKLKKLKKLGFNFPNTFHYIHTIKEIKKLYNNYTKKELEKINYKTKISGRIVNKRTFG
KALFFVIRNNNHDIQIYIKSNYFPKNYYQKNILELDLGDIIGVKGKIFKTNTCELSILCKKIYLLTKSLRSLPDKYFGLK
NQEIKYRKRYLDLISNNKIIKIFQKRSLIISNIRSFMKQKKFLEVETPMLHPIPGGANAKPFITYHNSLNEKMYLRIAPE
LYLKKLIIGGFNKIFEINRNFRNEGISTKHNPEFTMMEIYMSYSNYIDIMNLLEELCIFLVKKISKSLIIMYKSKKINFK
KPIKKMTMIESILKFNKNIDISNFKNIKNIKKTATNLNIKIDSNASLGEITNLIFEKTTEKKIIQPTFITEYPIEISPLA
KEKNKYFAERFEFFIAGYEIANGFSELNDPEEQKKRFKLQISKKNYTDKSKNFSYDKDYIIALEHGLPPTSGLGVGIDRL
IMILTNQKTIKDIIFFPLLKKI

Sequences:

>Translated_502_residues
MSKTLKIIQKKKSLEKELYTRKKKLKKLKKLGFNFPNTFHYIHTIKEIKKLYNNYTKKELEKINYKTKISGRIVNKRTFG
KALFFVIRNNNHDIQIYIKSNYFPKNYYQKNILELDLGDIIGVKGKIFKTNTCELSILCKKIYLLTKSLRSLPDKYFGLK
NQEIKYRKRYLDLISNNKIIKIFQKRSLIISNIRSFMKQKKFLEVETPMLHPIPGGANAKPFITYHNSLNEKMYLRIAPE
LYLKKLIIGGFNKIFEINRNFRNEGISTKHNPEFTMMEIYMSYSNYIDIMNLLEELCIFLVKKISKSLIIMYKSKKINFK
KPIKKMTMIESILKFNKNIDISNFKNIKNIKKTATNLNIKIDSNASLGEITNLIFEKTTEKKIIQPTFITEYPIEISPLA
KEKNKYFAERFEFFIAGYEIANGFSELNDPEEQKKRFKLQISKKNYTDKSKNFSYDKDYIIALEHGLPPTSGLGVGIDRL
IMILTNQKTIKDIIFFPLLKKI
>Mature_501_residues
SKTLKIIQKKKSLEKELYTRKKKLKKLKKLGFNFPNTFHYIHTIKEIKKLYNNYTKKELEKINYKTKISGRIVNKRTFGK
ALFFVIRNNNHDIQIYIKSNYFPKNYYQKNILELDLGDIIGVKGKIFKTNTCELSILCKKIYLLTKSLRSLPDKYFGLKN
QEIKYRKRYLDLISNNKIIKIFQKRSLIISNIRSFMKQKKFLEVETPMLHPIPGGANAKPFITYHNSLNEKMYLRIAPEL
YLKKLIIGGFNKIFEINRNFRNEGISTKHNPEFTMMEIYMSYSNYIDIMNLLEELCIFLVKKISKSLIIMYKSKKINFKK
PIKKMTMIESILKFNKNIDISNFKNIKNIKKTATNLNIKIDSNASLGEITNLIFEKTTEKKIIQPTFITEYPIEISPLAK
EKNKYFAERFEFFIAGYEIANGFSELNDPEEQKKRFKLQISKKNYTDKSKNFSYDKDYIIALEHGLPPTSGLGVGIDRLI
MILTNQKTIKDIIFFPLLKKI

Specific function: Unknown

COG id: COG1190

COG function: function code J; Lysyl-tRNA synthetase (class II)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI5031815, Length=497, Percent_Identity=38.2293762575453, Blast_Score=332, Evalue=5e-91,
Organism=Homo sapiens, GI194272210, Length=497, Percent_Identity=38.2293762575453, Blast_Score=332, Evalue=5e-91,
Organism=Homo sapiens, GI45439306, Length=469, Percent_Identity=21.9616204690832, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI40789249, Length=289, Percent_Identity=25.6055363321799, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789256, Length=492, Percent_Identity=49.1869918699187, Blast_Score=531, Evalue=1e-152,
Organism=Escherichia coli, GI1790571, Length=486, Percent_Identity=48.559670781893, Blast_Score=523, Evalue=1e-149,
Organism=Escherichia coli, GI87082379, Length=325, Percent_Identity=28.9230769230769, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1788173, Length=331, Percent_Identity=22.9607250755287, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17535925, Length=520, Percent_Identity=34.0384615384615, Blast_Score=310, Evalue=1e-84,
Organism=Caenorhabditis elegans, GI17535927, Length=520, Percent_Identity=34.0384615384615, Blast_Score=309, Evalue=2e-84,
Organism=Caenorhabditis elegans, GI71994340, Length=498, Percent_Identity=35.140562248996, Blast_Score=308, Evalue=4e-84,
Organism=Caenorhabditis elegans, GI17551876, Length=473, Percent_Identity=20.507399577167, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI32566633, Length=247, Percent_Identity=27.1255060728745, Blast_Score=89, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6320242, Length=508, Percent_Identity=39.5669291338583, Blast_Score=347, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6324256, Length=501, Percent_Identity=30.5389221556886, Blast_Score=163, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6323011, Length=470, Percent_Identity=24.0425531914894, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6325153, Length=263, Percent_Identity=29.277566539924, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24640849, Length=502, Percent_Identity=37.2509960159363, Blast_Score=344, Evalue=7e-95,
Organism=Drosophila melanogaster, GI24640851, Length=502, Percent_Identity=37.2509960159363, Blast_Score=344, Evalue=7e-95,
Organism=Drosophila melanogaster, GI17136276, Length=467, Percent_Identity=21.4132762312634, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24584738, Length=270, Percent_Identity=24.4444444444444, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYK_BUCCC (Q057G7)

Other databases:

- EMBL:   CP000263
- RefSeq:   YP_802825.1
- ProteinModelPortal:   Q057G7
- SMR:   Q057G7
- STRING:   Q057G7
- EnsemblBacteria:   EBBUCT00000001527
- GeneID:   4440856
- GenomeReviews:   CP000263_GR
- KEGG:   bcc:BCc_270
- eggNOG:   COG1190
- GeneTree:   EBGT00050000007970
- HOGENOM:   HBG631383
- OMA:   DEEAMIV
- BioCyc:   BAPH372461:BCC_270-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00252
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR002313
- InterPro:   IPR018149
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PANTHER:   PTHR22594:SF4
- PRINTS:   PR00982
- TIGRFAMs:   TIGR00499

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.6

Molecular weight: Translated: 59258; Mature: 59127

Theoretical pI: Translated: 10.53; Mature: 10.53

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTLKIIQKKKSLEKELYTRKKKLKKLKKLGFNFPNTFHYIHTIKEIKKLYNNYTKKEL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EKINYKTKISGRIVNKRTFGKALFFVIRNNNHDIQIYIKSNYFPKNYYQKNILELDLGDI
HHCCCEEEECCEEECCHHHCEEEEEEEECCCCEEEEEEECCCCCCHHHHCCCEEEECCCE
IGVKGKIFKTNTCELSILCKKIYLLTKSLRSLPDKYFGLKNQEIKYRKRYLDLISNNKII
ECCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHCCCCEE
KIFQKRSLIISNIRSFMKQKKFLEVETPMLHPIPGGANAKPFITYHNSLNEKMYLRIAPE
EEHHHHHHHHHHHHHHHHHHHCEEECCCEECCCCCCCCCCCEEEECCCCCCEEEEEECHH
LYLKKLIIGGFNKIFEINRNFRNEGISTKHNPEFTMMEIYMSYSNYIDIMNLLEELCIFL
HHHHHHHHHCCHHHHHHCCCHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
VKKISKSLIIMYKSKKINFKKPIKKMTMIESILKFNKNIDISNFKNIKNIKKTATNLNIK
HHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCEEEEE
IDSNASLGEITNLIFEKTTEKKIIQPTFITEYPIEISPLAKEKNKYFAERFEFFIAGYEI
ECCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCEECCCHHHHHHHHHHHHHHHHHHHHH
ANGFSELNDPEEQKKRFKLQISKKNYTDKSKNFSYDKDYIIALEHGLPPTSGLGVGIDRL
HCCHHHCCCCHHHHHHEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHH
IMILTNQKTIKDIIFFPLLKKI
EEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKTLKIIQKKKSLEKELYTRKKKLKKLKKLGFNFPNTFHYIHTIKEIKKLYNNYTKKEL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EKINYKTKISGRIVNKRTFGKALFFVIRNNNHDIQIYIKSNYFPKNYYQKNILELDLGDI
HHCCCEEEECCEEECCHHHCEEEEEEEECCCCEEEEEEECCCCCCHHHHCCCEEEECCCE
IGVKGKIFKTNTCELSILCKKIYLLTKSLRSLPDKYFGLKNQEIKYRKRYLDLISNNKII
ECCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHCCCCEE
KIFQKRSLIISNIRSFMKQKKFLEVETPMLHPIPGGANAKPFITYHNSLNEKMYLRIAPE
EEHHHHHHHHHHHHHHHHHHHCEEECCCEECCCCCCCCCCCEEEECCCCCCEEEEEECHH
LYLKKLIIGGFNKIFEINRNFRNEGISTKHNPEFTMMEIYMSYSNYIDIMNLLEELCIFL
HHHHHHHHHCCHHHHHHCCCHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
VKKISKSLIIMYKSKKINFKKPIKKMTMIESILKFNKNIDISNFKNIKNIKKTATNLNIK
HHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCEEEEE
IDSNASLGEITNLIFEKTTEKKIIQPTFITEYPIEISPLAKEKNKYFAERFEFFIAGYEI
ECCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCEECCCHHHHHHHHHHHHHHHHHHHHH
ANGFSELNDPEEQKKRFKLQISKKNYTDKSKNFSYDKDYIIALEHGLPPTSGLGVGIDRL
HCCHHHCCCCHHHHHHEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHH
IMILTNQKTIKDIIFFPLLKKI
EEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA