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The map label for this gene is typA [H]

Identifier: 116515193

GI number: 116515193

Start: 298730

End: 300544

Strand: Direct

Name: typA [H]

Synonym: BCc_267

Alternate gene names: 116515193

Gene position: 298730-300544 (Clockwise)

Preceding gene: 116515191

Following gene: 116515195

Centisome position: 71.74

GC content: 24.46

Gene sequence:

>1815_bases
ATGAAAAAAATAATAGCTCATGTTGATCATGGAAAAACAACATTATTAGATCAGTTACTAAAACAATCGGGTACATTTAA
AAAACATGAAGAAAAAATAGATAGAATTATGGATTCAAATGAATTAGAAAAAGAAAGAGGAATTACAATATTATCTAAAC
ATACATCAATAATATGGAAAAATTATCAAATCAATATTATTGATACTCCTGGACACGCTGATTTTGGAGGAGAAGTAGAA
AGAATATTATCTATGGTAGATTCTGTTTTATTAGTAGTAGATGCCTATGAAGGACCAATGCCACAAACAAGATATGTAAC
AAAAAAATCTTTTTTATATAAAATTAAACCAATTCTAGTAATTAATAAAATGGATAGAAATCCTATAAGAACAGATTGGG
TAATAAATAAAGTATTTGATTTATTTGTAAATTTATCCGCAAGTGATGAACAATTAGATTTTCCAATAATATATACATCA
GCTTTATTAGGAACTTCAGGGGAAGATCCTAATAATATGCAGAAAAATATGATTCCTTTATTAAATGCAATTATTAAATT
TACTCCTGAACCTAAAAAATCAAAAAATAATTTTTTTCAAATGCAAATATCACAATTAGATTTTAATAATTATTTTGGTA
TGATTGGAATAGGAAAAATACAACAAGGAAAATTAAAAAAAAATCAAGTTGTTTCAGTTCTTAGAGATAAAAAAAAGATT
TATACAGGAAAGATAAATAGTATCTTAAAATTTTATGGATTAGAACAAAAAAAAACAGAAACAGCATCAGCGGGAGATAT
TATAGCAATTACAGGTTTAAATAACATATCAATTTCAGACACTATTTGCGATCCTGAATTTTTGTGTTCTTTACCAAAAT
TAAAAATTGATAAACCTACAGTAAATATGTTTTTTTGTGTAAATCAATCACCTTTTTGTGGAAAGGAAGGAAAAAATATA
ACATCACGGCAAATATTGGAACGATTAAAAAAAGAAACAGTAAGAAATATTTCTTTAAAAGTAAAAGAAACAAAAAATTC
TAATGTATTTTCTGTTTCTGGTAGAGGAGAATTACATTTATCGATTTTATTAGAGCAATTACGAAGAGAAAATTTTGAAT
TAGAAGTTTCAAAACCAAAAGTAATTTTAAAAAAAAAAGATAATGTATTAACTGAACCATTCGAAATAGCAATACTTGAT
ATTAAAAAAAATCATCAAGGACAAATAATAAAAAAAATAGGAGAGTTAAGAGGAGAAATAAAAGAATTAACAAATCAAGA
AAATGATAGAATTCAAATAGAATGTATATTATCTAGTAGATCATTAATTGGATTTAGATCTGAATTTATGAATATTACTT
CTGGTAGTGGTACTTTTTTTTCTTCTATTAGTCATTATGGTCCTATACAAAAAAAGCAATTCGGGCAAAGAAAAAATGGA
GTATTAATTTCAAAAAATACTGGCATAGCTGTATCTTTTTCAATTAATAATTTACAAAATAGAGGAAAAATGTTTATCTC
TCATGGAGAAAAAGTTTATGAAGGACAAATTATTGGAATACATAATAGATCTAATGATCTAACGGTAAACTGCTTAACTG
GAAAAAAGTTAACTAACATGCGTGCTTCAGGTACTGATGAAGCAATACATTTAGTTAAACCAATTAAAATTACATTAGAA
TATGCATTAAATTTTGTTAATGATGACGAATTAATTGAAATAACACCCAATTCAATACGATTTAGAAAATTATATTTAAA
AGAAAGTGATAGAAAAAAAGCAAAAAAAGAAAAAAAAATATACTACTATAATTAA

Upstream 100 bases:

>100_bases
ATATATAATAATAAAATTAATTTTTAATTTAAAAATTAATATTTTGAAAAAATTATAATTTTTTATAATTTTGATTATTT
TCTTTAAAAATGGTATAAAA

Downstream 100 bases:

>100_bases
AAAAAATTAAAATAATTTATAAAAGAGAATCTTTATATACAAATAAAAGATTCTTTTTCATAATTTAAGCATATTAATAA
AATTTTTATAAAAATATTTT

Product: GTP-binding elongation factor family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 604; Mature: 604

Protein sequence:

>604_residues
MKKIIAHVDHGKTTLLDQLLKQSGTFKKHEEKIDRIMDSNELEKERGITILSKHTSIIWKNYQINIIDTPGHADFGGEVE
RILSMVDSVLLVVDAYEGPMPQTRYVTKKSFLYKIKPILVINKMDRNPIRTDWVINKVFDLFVNLSASDEQLDFPIIYTS
ALLGTSGEDPNNMQKNMIPLLNAIIKFTPEPKKSKNNFFQMQISQLDFNNYFGMIGIGKIQQGKLKKNQVVSVLRDKKKI
YTGKINSILKFYGLEQKKTETASAGDIIAITGLNNISISDTICDPEFLCSLPKLKIDKPTVNMFFCVNQSPFCGKEGKNI
TSRQILERLKKETVRNISLKVKETKNSNVFSVSGRGELHLSILLEQLRRENFELEVSKPKVILKKKDNVLTEPFEIAILD
IKKNHQGQIIKKIGELRGEIKELTNQENDRIQIECILSSRSLIGFRSEFMNITSGSGTFFSSISHYGPIQKKQFGQRKNG
VLISKNTGIAVSFSINNLQNRGKMFISHGEKVYEGQIIGIHNRSNDLTVNCLTGKKLTNMRASGTDEAIHLVKPIKITLE
YALNFVNDDELIEITPNSIRFRKLYLKESDRKKAKKEKKIYYYN

Sequences:

>Translated_604_residues
MKKIIAHVDHGKTTLLDQLLKQSGTFKKHEEKIDRIMDSNELEKERGITILSKHTSIIWKNYQINIIDTPGHADFGGEVE
RILSMVDSVLLVVDAYEGPMPQTRYVTKKSFLYKIKPILVINKMDRNPIRTDWVINKVFDLFVNLSASDEQLDFPIIYTS
ALLGTSGEDPNNMQKNMIPLLNAIIKFTPEPKKSKNNFFQMQISQLDFNNYFGMIGIGKIQQGKLKKNQVVSVLRDKKKI
YTGKINSILKFYGLEQKKTETASAGDIIAITGLNNISISDTICDPEFLCSLPKLKIDKPTVNMFFCVNQSPFCGKEGKNI
TSRQILERLKKETVRNISLKVKETKNSNVFSVSGRGELHLSILLEQLRRENFELEVSKPKVILKKKDNVLTEPFEIAILD
IKKNHQGQIIKKIGELRGEIKELTNQENDRIQIECILSSRSLIGFRSEFMNITSGSGTFFSSISHYGPIQKKQFGQRKNG
VLISKNTGIAVSFSINNLQNRGKMFISHGEKVYEGQIIGIHNRSNDLTVNCLTGKKLTNMRASGTDEAIHLVKPIKITLE
YALNFVNDDELIEITPNSIRFRKLYLKESDRKKAKKEKKIYYYN
>Mature_604_residues
MKKIIAHVDHGKTTLLDQLLKQSGTFKKHEEKIDRIMDSNELEKERGITILSKHTSIIWKNYQINIIDTPGHADFGGEVE
RILSMVDSVLLVVDAYEGPMPQTRYVTKKSFLYKIKPILVINKMDRNPIRTDWVINKVFDLFVNLSASDEQLDFPIIYTS
ALLGTSGEDPNNMQKNMIPLLNAIIKFTPEPKKSKNNFFQMQISQLDFNNYFGMIGIGKIQQGKLKKNQVVSVLRDKKKI
YTGKINSILKFYGLEQKKTETASAGDIIAITGLNNISISDTICDPEFLCSLPKLKIDKPTVNMFFCVNQSPFCGKEGKNI
TSRQILERLKKETVRNISLKVKETKNSNVFSVSGRGELHLSILLEQLRRENFELEVSKPKVILKKKDNVLTEPFEIAILD
IKKNHQGQIIKKIGELRGEIKELTNQENDRIQIECILSSRSLIGFRSEFMNITSGSGTFFSSISHYGPIQKKQFGQRKNG
VLISKNTGIAVSFSINNLQNRGKMFISHGEKVYEGQIIGIHNRSNDLTVNCLTGKKLTNMRASGTDEAIHLVKPIKITLE
YALNFVNDDELIEITPNSIRFRKLYLKESDRKKAKKEKKIYYYN

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=400, Percent_Identity=32.75, Blast_Score=133, Evalue=6e-31,
Organism=Homo sapiens, GI94966754, Length=127, Percent_Identity=45.6692913385827, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI18390331, Length=136, Percent_Identity=46.3235294117647, Blast_Score=109, Evalue=8e-24,
Organism=Homo sapiens, GI25306287, Length=448, Percent_Identity=25.2232142857143, Blast_Score=104, Evalue=3e-22,
Organism=Homo sapiens, GI34147630, Length=270, Percent_Identity=30.7407407407407, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI4503483, Length=139, Percent_Identity=38.1294964028777, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI25306283, Length=125, Percent_Identity=40.8, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI19923640, Length=155, Percent_Identity=36.1290322580645, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI310132016, Length=105, Percent_Identity=43.8095238095238, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI310110807, Length=105, Percent_Identity=43.8095238095238, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI310123363, Length=105, Percent_Identity=43.8095238095238, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI94966752, Length=81, Percent_Identity=45.679012345679, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI217272892, Length=131, Percent_Identity=33.587786259542, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI217272894, Length=131, Percent_Identity=33.587786259542, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI48994988, Length=596, Percent_Identity=59.5637583892617, Blast_Score=781, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=392, Percent_Identity=27.5510204081633, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI1789738, Length=132, Percent_Identity=42.4242424242424, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1790835, Length=130, Percent_Identity=34.6153846153846, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1790412, Length=233, Percent_Identity=28.3261802575107, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1789737, Length=233, Percent_Identity=28.3261802575107, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17556745, Length=444, Percent_Identity=25.9009009009009, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17557151, Length=235, Percent_Identity=31.4893617021277, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17533571, Length=129, Percent_Identity=42.6356589147287, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71988811, Length=123, Percent_Identity=41.4634146341463, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71988819, Length=123, Percent_Identity=41.4634146341463, Blast_Score=96, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17506493, Length=167, Percent_Identity=32.9341317365269, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17552882, Length=129, Percent_Identity=37.984496124031, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17556456, Length=286, Percent_Identity=28.3216783216783, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI25141371, Length=278, Percent_Identity=29.8561151079137, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323320, Length=476, Percent_Identity=27.3109243697479, Blast_Score=116, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6324707, Length=139, Percent_Identity=39.568345323741, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6320593, Length=139, Percent_Identity=39.568345323741, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6323098, Length=140, Percent_Identity=42.8571428571429, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322359, Length=145, Percent_Identity=43.448275862069, Blast_Score=98, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6324761, Length=266, Percent_Identity=27.8195488721804, Blast_Score=94, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6324166, Length=137, Percent_Identity=37.2262773722628, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI78706572, Length=539, Percent_Identity=26.1595547309833, Blast_Score=133, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24582462, Length=135, Percent_Identity=45.1851851851852, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24585709, Length=143, Percent_Identity=38.4615384615385, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24585711, Length=143, Percent_Identity=38.4615384615385, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24585713, Length=143, Percent_Identity=38.4615384615385, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28574573, Length=132, Percent_Identity=40.9090909090909, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI281363316, Length=297, Percent_Identity=26.5993265993266, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17864358, Length=297, Percent_Identity=26.5993265993266, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357743, Length=129, Percent_Identity=35.6589147286822, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221458488, Length=125, Percent_Identity=39.2, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19921738, Length=241, Percent_Identity=29.8755186721992, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 68878; Mature: 68878

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIIAHVDHGKTTLLDQLLKQSGTFKKHEEKIDRIMDSNELEKERGITILSKHTSIIWK
CCCEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHCCCEEEECCCEEEEE
NYQINIIDTPGHADFGGEVERILSMVDSVLLVVDAYEGPMPQTRYVTKKSFLYKIKPILV
EEEEEEEECCCCCCCCHHHHHHHHHHHHHEEEEECCCCCCCCCEEEHHHHHEEEECEEEE
INKMDRNPIRTDWVINKVFDLFVNLSASDEQLDFPIIYTSALLGTSGEDPNNMQKNMIPL
EECCCCCCCCHHHHHHHHHHHHEECCCCCCCCCCCEEEEEHHHCCCCCCCCCHHHHHHHH
LNAIIKFTPEPKKSKNNFFQMQISQLDFNNYFGMIGIGKIQQGKLKKNQVVSVLRDKKKI
HHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHH
YTGKINSILKFYGLEQKKTETASAGDIIAITGLNNISISDTICDPEFLCSLPKLKIDKPT
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHCCCCEECCCCC
VNMFFCVNQSPFCGKEGKNITSRQILERLKKETVRNISLKVKETKNSNVFSVSGRGELHL
EEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEEECCCCCEEEECCCCCCHH
SILLEQLRRENFELEVSKPKVILKKKDNVLTEPFEIAILDIKKNHQGQIIKKIGELRGEI
HHHHHHHHHCCCEEEECCCEEEEEECCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHH
KELTNQENDRIQIECILSSRSLIGFRSEFMNITSGSGTFFSSISHYGPIQKKQFGQRKNG
HHHCCCCCCEEEEEEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHCCCCCCC
VLISKNTGIAVSFSINNLQNRGKMFISHGEKVYEGQIIGIHNRSNDLTVNCLTGKKLTNM
EEEECCCCEEEEEEECCCCCCCCEEEECCCEEECCEEEEEEECCCCEEEEEECCCCCCCC
RASGTDEAIHLVKPIKITLEYALNFVNDDELIEITPNSIRFRKLYLKESDRKKAKKEKKI
CCCCCCCEEEEECCCEEEEEEHHEECCCCCEEEECCCCEEEEEEEECCCHHHHHHHHCCE
YYYN
EEEC
>Mature Secondary Structure
MKKIIAHVDHGKTTLLDQLLKQSGTFKKHEEKIDRIMDSNELEKERGITILSKHTSIIWK
CCCEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHCCCEEEECCCEEEEE
NYQINIIDTPGHADFGGEVERILSMVDSVLLVVDAYEGPMPQTRYVTKKSFLYKIKPILV
EEEEEEEECCCCCCCCHHHHHHHHHHHHHEEEEECCCCCCCCCEEEHHHHHEEEECEEEE
INKMDRNPIRTDWVINKVFDLFVNLSASDEQLDFPIIYTSALLGTSGEDPNNMQKNMIPL
EECCCCCCCCHHHHHHHHHHHHEECCCCCCCCCCCEEEEEHHHCCCCCCCCCHHHHHHHH
LNAIIKFTPEPKKSKNNFFQMQISQLDFNNYFGMIGIGKIQQGKLKKNQVVSVLRDKKKI
HHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHH
YTGKINSILKFYGLEQKKTETASAGDIIAITGLNNISISDTICDPEFLCSLPKLKIDKPT
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHCCCCEECCCCC
VNMFFCVNQSPFCGKEGKNITSRQILERLKKETVRNISLKVKETKNSNVFSVSGRGELHL
EEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEEECCCCCEEEECCCCCCHH
SILLEQLRRENFELEVSKPKVILKKKDNVLTEPFEIAILDIKKNHQGQIIKKIGELRGEI
HHHHHHHHHCCCEEEECCCEEEEEECCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHH
KELTNQENDRIQIECILSSRSLIGFRSEFMNITSGSGTFFSSISHYGPIQKKQFGQRKNG
HHHCCCCCCEEEEEEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHCCCCCCC
VLISKNTGIAVSFSINNLQNRGKMFISHGEKVYEGQIIGIHNRSNDLTVNCLTGKKLTNM
EEEECCCCEEEEEEECCCCCCCCEEEECCCEEECCEEEEEEECCCCEEEEEECCCCCCCC
RASGTDEAIHLVKPIKITLEYALNFVNDDELIEITPNSIRFRKLYLKESDRKKAKKEKKI
CCCCCCCEEEEECCCEEEEEEHHEECCCCCEEEECCCCEEEEEEEECCCHHHHHHHHCCE
YYYN
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]