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The map label for this gene is rnc

Identifier: 116515099

GI number: 116515099

Start: 189225

End: 189905

Strand: Reverse

Name: rnc

Synonym: BCc_163

Alternate gene names: 116515099

Gene position: 189905-189225 (Counterclockwise)

Preceding gene: 116515100

Following gene: 116515098

Centisome position: 45.61

GC content: 26.73

Gene sequence:

>681_bases
ATGAATCCAATAGTGATGAAAAAATTACAAAAATTTATCGGTTATACATTTACAAATATAACATTATTAAAACATGCATT
AACACATAGAAGTGCAAGCTCTCAACATAATGAACGATTGGAATTTTTAGGAGATTCAATTCTTAGTTTTATTATTGCTA
AAGCATTATATCATCATTTTCCTAAAATGAATGAAGGTGGAATGAGTAGAATGAGAGCTACATTAGTTAGAGGTAATACA
CTGGCTGAGATTGCTACTGAATTTTCTTTAGGAAAATATTTACAATTAGGGCAAGGAGAAAAAAAAAGTGGTGGTTTTAA
ACGTGAATCTATATTAGCTAATGCTATAGAAGCAATAATAGCAAGTATATTTTTAGACAGTAATATTTATACTGTAGAAA
GAATAATTTTATATTGGTATAAAAATCGTTTCAAAAAAATGAATCCAACAGGAACAAAAAAAGATCCAAAAACTAGATTA
CAAGAATATCTACAATCAAAACATTTTTCTTTACCAATATATAGTATTGGACAAATATATGGAGAAGCTCATAATCAAAT
TTTTACTATTTATTGTAAAATTGATGGATTATCAGAATTATTAATTGGAATAGGTGCAAGTAGAAGAAAAGCAGAACAAG
ATGCAGCACAAAATGCATTAATTAGATTAGAGGTAGAATAA

Upstream 100 bases:

>100_bases
CAAAAAAAATAAAATAAAAATATTATATTTAGCAAATTATTGATTTAAAATATTTTATATAAAAAATGTATTAATAATTT
TAATTTTTAATTAATATAAA

Downstream 100 bases:

>100_bases
AAATAATGCAAAAAAAAACTTTTTTTGGAAAAATTATCATAGTCGGAAGGACTAATGTTGGAAAATCTACATTATTAAAT
AAATTAATTAAGTCTAATAT

Product: hypothetical protein

Products: NA

Alternate protein names: Ribonuclease III; RNase III

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MNPIVMKKLQKFIGYTFTNITLLKHALTHRSASSQHNERLEFLGDSILSFIIAKALYHHFPKMNEGGMSRMRATLVRGNT
LAEIATEFSLGKYLQLGQGEKKSGGFKRESILANAIEAIIASIFLDSNIYTVERIILYWYKNRFKKMNPTGTKKDPKTRL
QEYLQSKHFSLPIYSIGQIYGEAHNQIFTIYCKIDGLSELLIGIGASRRKAEQDAAQNALIRLEVE

Sequences:

>Translated_226_residues
MNPIVMKKLQKFIGYTFTNITLLKHALTHRSASSQHNERLEFLGDSILSFIIAKALYHHFPKMNEGGMSRMRATLVRGNT
LAEIATEFSLGKYLQLGQGEKKSGGFKRESILANAIEAIIASIFLDSNIYTVERIILYWYKNRFKKMNPTGTKKDPKTRL
QEYLQSKHFSLPIYSIGQIYGEAHNQIFTIYCKIDGLSELLIGIGASRRKAEQDAAQNALIRLEVE
>Mature_226_residues
MNPIVMKKLQKFIGYTFTNITLLKHALTHRSASSQHNERLEFLGDSILSFIIAKALYHHFPKMNEGGMSRMRATLVRGNT
LAEIATEFSLGKYLQLGQGEKKSGGFKRESILANAIEAIIASIFLDSNIYTVERIILYWYKNRFKKMNPTGTKKDPKTRL
QEYLQSKHFSLPIYSIGQIYGEAHNQIFTIYCKIDGLSELLIGIGASRRKAEQDAAQNALIRLEVE

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain

Homologues:

Organism=Homo sapiens, GI155030234, Length=229, Percent_Identity=30.5676855895196, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI155030236, Length=229, Percent_Identity=30.5676855895196, Blast_Score=108, Evalue=4e-24,
Organism=Escherichia coli, GI1788920, Length=226, Percent_Identity=64.6017699115044, Blast_Score=305, Evalue=2e-84,
Organism=Caenorhabditis elegans, GI17506883, Length=227, Percent_Identity=29.5154185022026, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193202651, Length=227, Percent_Identity=29.5154185022026, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17137682, Length=230, Percent_Identity=28.2608695652174, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNC_BUCCC (Q057R4)

Other databases:

- EMBL:   CP000263
- RefSeq:   YP_802728.1
- ProteinModelPortal:   Q057R4
- SMR:   Q057R4
- STRING:   Q057R4
- EnsemblBacteria:   EBBUCT00000001362
- GeneID:   4441010
- GenomeReviews:   CP000263_GR
- KEGG:   bcc:BCc_163
- eggNOG:   COG0571
- GeneTree:   EBGT00050000008067
- HOGENOM:   HBG744556
- OMA:   ALTHKSF
- BioCyc:   BAPH372461:BCC_163-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00104
- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907
- Gene3D:   G3DSA:3.30.160.20
- Gene3D:   G3DSA:1.10.1520.10
- SMART:   SM00358
- SMART:   SM00535
- TIGRFAMs:   TIGR02191

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3; SSF69065 RNase_III

EC number: =3.1.26.3

Molecular weight: Translated: 25705; Mature: 25705

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: PS50137 DS_RBD; PS00517 RNASE_3_1; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPIVMKKLQKFIGYTFTNITLLKHALTHRSASSQHNERLEFLGDSILSFIIAKALYHHF
CCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
PKMNEGGMSRMRATLVRGNTLAEIATEFSLGKYLQLGQGEKKSGGFKRESILANAIEAII
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
ASIFLDSNIYTVERIILYWYKNRFKKMNPTGTKKDPKTRLQEYLQSKHFSLPIYSIGQIY
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
GEAHNQIFTIYCKIDGLSELLIGIGASRRKAEQDAAQNALIRLEVE
HHHCCEEEEEEEEECCHHHHHHHCCCCHHHHHHHHHCCCEEEEEEC
>Mature Secondary Structure
MNPIVMKKLQKFIGYTFTNITLLKHALTHRSASSQHNERLEFLGDSILSFIIAKALYHHF
CCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
PKMNEGGMSRMRATLVRGNTLAEIATEFSLGKYLQLGQGEKKSGGFKRESILANAIEAII
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
ASIFLDSNIYTVERIILYWYKNRFKKMNPTGTKKDPKTRLQEYLQSKHFSLPIYSIGQIY
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
GEAHNQIFTIYCKIDGLSELLIGIGASRRKAEQDAAQNALIRLEVE
HHHCCEEEEEEEEECCHHHHHHHCCCCHHHHHHHHHCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA