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The map label for this gene is lepB [H]

Identifier: 116515100

GI number: 116515100

Start: 189989

End: 190846

Strand: Reverse

Name: lepB [H]

Synonym: BCc_164

Alternate gene names: 116515100

Gene position: 190846-189989 (Counterclockwise)

Preceding gene: 116515101

Following gene: 116515099

Centisome position: 45.83

GC content: 13.99

Gene sequence:

>858_bases
ATGAAAATTATAATAAGAAAAATATTATTATTATTATCATTAATAATAATATTTTTATTAATTATAAATTTTATAAAAAA
AAAAAAAAATGAAGTAAAGAAGAAAAAAAAAAATAAAAGTTTTTATATTATACTTATAATTATTTTTATTCGATTTTTTG
TTTATGAATCATTTATAATCTCTTCTAATTCAATGAATCCAACATTATTAACAGGAGATTTTATATTAGTACAAAAATTT
TTCTATAATAACAATTTCATTAATAATATTTTTTTTAAAAAATTTAAACCTGAAAGAAATGATATTATTGTTTTTAAATA
TCCAAAAAACAATAAATTAAATTTTGTTAAACGTATTATAGGTTTACCTGGAGAAGTAATTATATATAATCCATACAATA
AAAAATTATATATTATAAAAAAAAACAAACATACAAGAGAAAAAAAAAACATTTTTAAAATCATAAAAAATAAAATCAAA
ATTAATAAATTAATTAATAAAAAAAGGAAATTTAAAACAAATAAAAATGTATATTTATCACCAATAAAAAAAATATATAT
AGAAAAAATTCAAAATAACATTCATAATATTGTAATTTCAACCGGCATAAAAAATTGTTTACATCTTTTTAGTAAAAAAT
ATAATAATAAAGAAAATTGGATATGGAAAATTCCAAAAAATAAATATTTTGTTCTAGGAGATAATAGAGATTATAGTTTA
GATAGTAGATTTTGGGGATTAATATCTAAAAAAAATATTTTAGGTAAAGTAAAATATATATGGTTAAGTATTAATTATAA
AAGTAAAAATTGGTTTAAAAAAATACGTTTTTATAGAATTTCAAAAAAAATAAAATAA

Upstream 100 bases:

>100_bases
AAGGAAAAAAAAGAATGAAGATAATTGGAAATATTAAAATCCCTCAAGAAGTTTTTTTTACAATATTAAAAATAAATTAA
TCAATATTAGGAATAATATA

Downstream 100 bases:

>100_bases
AAATATTATATTTAGCAAATTATTGATTTAAAATATTTTATATAAAAAATGTATTAATAATTTTAATTTTTAATTAATAT
AAAATGAATCCAATAGTGAT

Product: hypothetical protein

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MKIIIRKILLLLSLIIIFLLIINFIKKKKNEVKKKKKNKSFYIILIIIFIRFFVYESFIISSNSMNPTLLTGDFILVQKF
FYNNNFINNIFFKKFKPERNDIIVFKYPKNNKLNFVKRIIGLPGEVIIYNPYNKKLYIIKKNKHTREKKNIFKIIKNKIK
INKLINKKRKFKTNKNVYLSPIKKIYIEKIQNNIHNIVISTGIKNCLHLFSKKYNNKENWIWKIPKNKYFVLGDNRDYSL
DSRFWGLISKKNILGKVKYIWLSINYKSKNWFKKIRFYRISKKIK

Sequences:

>Translated_285_residues
MKIIIRKILLLLSLIIIFLLIINFIKKKKNEVKKKKKNKSFYIILIIIFIRFFVYESFIISSNSMNPTLLTGDFILVQKF
FYNNNFINNIFFKKFKPERNDIIVFKYPKNNKLNFVKRIIGLPGEVIIYNPYNKKLYIIKKNKHTREKKNIFKIIKNKIK
INKLINKKRKFKTNKNVYLSPIKKIYIEKIQNNIHNIVISTGIKNCLHLFSKKYNNKENWIWKIPKNKYFVLGDNRDYSL
DSRFWGLISKKNILGKVKYIWLSINYKSKNWFKKIRFYRISKKIK
>Mature_285_residues
MKIIIRKILLLLSLIIIFLLIINFIKKKKNEVKKKKKNKSFYIILIIIFIRFFVYESFIISSNSMNPTLLTGDFILVQKF
FYNNNFINNIFFKKFKPERNDIIVFKYPKNNKLNFVKRIIGLPGEVIIYNPYNKKLYIIKKNKHTREKKNIFKIIKNKIK
INKLINKKRKFKTNKNVYLSPIKKIYIEKIQNNIHNIVISTGIKNCLHLFSKKYNNKENWIWKIPKNKYFVLGDNRDYSL
DSRFWGLISKKNILGKVKYIWLSINYKSKNWFKKIRFYRISKKIK

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=255, Percent_Identity=30.1960784313725, Blast_Score=162, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056
- InterPro:   IPR019533
- InterPro:   IPR019766 [H]

Pfam domain/function: PF00717 Peptidase_S24; PF10502 Peptidase_S26 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 34654; Mature: 34654

Theoretical pI: Translated: 11.14; Mature: 11.14

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIIRKILLLLSLIIIFLLIINFIKKKKNEVKKKKKNKSFYIILIIIFIRFFVYESFII
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHE
SSNSMNPTLLTGDFILVQKFFYNNNFINNIFFKKFKPERNDIIVFKYPKNNKLNFVKRII
ECCCCCCEEEECHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHH
GLPGEVIIYNPYNKKLYIIKKNKHTREKKNIFKIIKNKIKINKLINKKRKFKTNKNVYLS
CCCCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEH
PIKKIYIEKIQNNIHNIVISTGIKNCLHLFSKKYNNKENWIWKIPKNKYFVLGDNRDYSL
HHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCCCCC
DSRFWGLISKKNILGKVKYIWLSINYKSKNWFKKIRFYRISKKIK
CHHHHHHHHCCCHHEEEEEEEEEEEECCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKIIIRKILLLLSLIIIFLLIINFIKKKKNEVKKKKKNKSFYIILIIIFIRFFVYESFII
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHE
SSNSMNPTLLTGDFILVQKFFYNNNFINNIFFKKFKPERNDIIVFKYPKNNKLNFVKRII
ECCCCCCEEEECHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHH
GLPGEVIIYNPYNKKLYIIKKNKHTREKKNIFKIIKNKIKINKLINKKRKFKTNKNVYLS
CCCCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEH
PIKKIYIEKIQNNIHNIVISTGIKNCLHLFSKKYNNKENWIWKIPKNKYFVLGDNRDYSL
HHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCCCCC
DSRFWGLISKKNILGKVKYIWLSINYKSKNWFKKIRFYRISKKIK
CHHHHHHHHCCCHHEEEEEEEEEEEECCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12522265 [H]