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The map label for this gene is pth

Identifier: 116515063

GI number: 116515063

Start: 139571

End: 140149

Strand: Direct

Name: pth

Synonym: BCc_123

Alternate gene names: 116515063

Gene position: 139571-140149 (Clockwise)

Preceding gene: 116515061

Following gene: 116515064

Centisome position: 33.52

GC content: 19.34

Gene sequence:

>579_bases
ATGAATAAAATAAAGATGATTGTTGGGTTAGGAAATTCAGTATATAAATATAATCAAACAAGACATAATGTTGGTTTTTG
GTATATAAATATGTTATCAAGTTTTTATAAAACTTCTTTGAAATTTAAAAAAAAATTTTCTGGTTATGTTTCTTCTTTTT
TTTTAAATAATAACAAAATATTTTTATTAAAACCTGATTTATTTATGAATTTAAATGGTTATTCTGTTTTTGCATTGTCA
TCTTTTTATAAAATTAAATTATCTGAAATTTTAGTTGTACGTGATGAATTAGATTTGTCTCCAGGTATTTTAAAGGTGAA
ATATGGTATAGGTCATAATGGACATAATGGGGTCAAAAGTATTATTAATACTTTTGAAAAAAAAAAACCTTTTATTCAAT
TATGTATAGGTATTGGTCGACCAGAATTTAAAAAGAATGTATCTAATTTTGTTTTAGAATGTCCAAGTAAAATAGATACA
ATAAATATAAAAAAAGCAATTTTAAAGTTTATTTTTTTAACTAAAGATTATATCTATAAGAAAGAATTTTTAAAAAATAA
AAAAATTATTTTAATTTAA

Upstream 100 bases:

>100_bases
ATTATTTTTTATTTTTTTAAAAATTGTTTGTTTAATGAACAATATTTTTATTAAATATAATATTTTTATTTTTTGCTTTT
TATAATGAGAAGAAGATTTT

Downstream 100 bases:

>100_bases
TTTTTTTTTAATTTAAAAGTTTTATTTTTTTAAAATTATACAGGTAAATATTATCGTGGTATATAAATTTGGTATTATCG
GATTACCTAATGTAGGAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: PTH

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MNKIKMIVGLGNSVYKYNQTRHNVGFWYINMLSSFYKTSLKFKKKFSGYVSSFFLNNNKIFLLKPDLFMNLNGYSVFALS
SFYKIKLSEILVVRDELDLSPGILKVKYGIGHNGHNGVKSIINTFEKKKPFIQLCIGIGRPEFKKNVSNFVLECPSKIDT
INIKKAILKFIFLTKDYIYKKEFLKNKKIILI

Sequences:

>Translated_192_residues
MNKIKMIVGLGNSVYKYNQTRHNVGFWYINMLSSFYKTSLKFKKKFSGYVSSFFLNNNKIFLLKPDLFMNLNGYSVFALS
SFYKIKLSEILVVRDELDLSPGILKVKYGIGHNGHNGVKSIINTFEKKKPFIQLCIGIGRPEFKKNVSNFVLECPSKIDT
INIKKAILKFIFLTKDYIYKKEFLKNKKIILI
>Mature_192_residues
MNKIKMIVGLGNSVYKYNQTRHNVGFWYINMLSSFYKTSLKFKKKFSGYVSSFFLNNNKIFLLKPDLFMNLNGYSVFALS
SFYKIKLSEILVVRDELDLSPGILKVKYGIGHNGHNGVKSIINTFEKKKPFIQLCIGIGRPEFKKNVSNFVLECPSKIDT
INIKKAILKFIFLTKDYIYKKEFLKNKKIILI

Specific function: The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis

COG id: COG0193

COG function: function code J; Peptidyl-tRNA hydrolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTH family

Homologues:

Organism=Homo sapiens, GI50897284, Length=178, Percent_Identity=29.2134831460674, Blast_Score=84, Evalue=6e-17,
Organism=Escherichia coli, GI1787455, Length=164, Percent_Identity=45.1219512195122, Blast_Score=122, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PTH_BUCCC (Q057V0)

Other databases:

- EMBL:   CP000263
- RefSeq:   YP_802692.1
- ProteinModelPortal:   Q057V0
- SMR:   Q057V0
- STRING:   Q057V0
- EnsemblBacteria:   EBBUCT00000001506
- GeneID:   4440833
- GenomeReviews:   CP000263_GR
- KEGG:   bcc:BCc_123
- eggNOG:   COG0193
- GeneTree:   EBGT00050000008081
- HOGENOM:   HBG610927
- OMA:   IGKPPGQ
- BioCyc:   BAPH372461:BCC_123-MONOMER
- GO:   GO:0005737
- GO:   GO:0006412
- HAMAP:   MF_00083
- InterPro:   IPR001328
- InterPro:   IPR018171
- Gene3D:   G3DSA:3.40.50.1470
- PANTHER:   PTHR17224
- TIGRFAMs:   TIGR00447

Pfam domain/function: PF01195 Pept_tRNA_hydro; SSF53178 Pept_tRNA_hydro

EC number: =3.1.1.29

Molecular weight: Translated: 22308; Mature: 22308

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: PS01195 PEPT_TRNA_HYDROL_1; PS01196 PEPT_TRNA_HYDROL_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIKMIVGLGNSVYKYNQTRHNVGFWYINMLSSFYKTSLKFKKKFSGYVSSFFLNNNKI
CCCEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEE
FLLKPDLFMNLNGYSVFALSSFYKIKLSEILVVRDELDLSPGILKVKYGIGHNGHNGVKS
EEECCCCEEECCCEEEEEEHHHHEEEEEEEEEEECCCCCCCCEEEEEECCCCCCCHHHHH
IINTFEKKKPFIQLCIGIGRPEFKKNVSNFVLECPSKIDTINIKKAILKFIFLTKDYIYK
HHHHHHHCCCCEEHHHHCCCHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHH
KEFLKNKKIILI
HHHHCCCCEEEC
>Mature Secondary Structure
MNKIKMIVGLGNSVYKYNQTRHNVGFWYINMLSSFYKTSLKFKKKFSGYVSSFFLNNNKI
CCCEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEE
FLLKPDLFMNLNGYSVFALSSFYKIKLSEILVVRDELDLSPGILKVKYGIGHNGHNGVKS
EEECCCCEEECCCEEEEEEHHHHEEEEEEEEEEECCCCCCCCEEEEEECCCCCCCHHHHH
IINTFEKKKPFIQLCIGIGRPEFKKNVSNFVLECPSKIDTINIKKAILKFIFLTKDYIYK
HHHHHHHCCCCEEHHHHCCCHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHH
KEFLKNKKIILI
HHHHCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA