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The map label for this gene is aroC

Identifier: 116515003

GI number: 116515003

Start: 68027

End: 69088

Strand: Reverse

Name: aroC

Synonym: BCc_061

Alternate gene names: 116515003

Gene position: 69088-68027 (Counterclockwise)

Preceding gene: 116515015

Following gene: 116515002

Centisome position: 16.59

GC content: 29.28

Gene sequence:

>1062_bases
ATGCCGGGAAATTCAATTGGAAAAATATTTAAAGTTACTACATGTGGGGAATCACATGGACCTATGTTAGCAGGAATTAT
TGATGGAGTTCCGCCTGGTTTATCTTTAAACAATAAAGATATTCAATATGAATTAAATAGAAGAAGACCGGGTTTTTCTA
AATTTACATCACAAAGAAGAGAAAAAGATAAAGTAGAAATATTTTCAGGAATATTTAAAGGAATAACTACTGGAACAAGT
ATAGGCATAAGAATAAAAAATATAGATATTAGATCACAAGATTATTCAGAAATTAAAAATTTATATCGACCTAATCATGC
TGATTATACATATGAAAAAAAATATGGAATCAGAGATTATAGAGGTGGAGGAAGATCCTCAGCTAGAGAAACAGCTATTC
GAGTAGCTGCTGGAGCTATTGCTAAAAAATATTTAAAATTACAACATAATATAAAAATTAGAGGATATTTGTCACAAATA
GGATCAATTTATTGTCCATTTCAATCTTGGGAAGAAGTAGAAAAAAATCCTTTTTTTTGTAGTAATTCAGAAAAAATAAA
AAAAATTATACATTTTATCAAAAAATTAAAAAAAAGTGGAAATTCAGTAGGAGCAAAAATTACTATTATTGCTAAAAATG
TTCCTATTGGATTAGGAGAACCTGTATTTGATAGACTAAATGCTGAAATTGCACATTCTATAATGAGTATTAATGCTGCT
AAATCTATTGAAATTGGAGATGGAATTCATGTAGCTAAACAAACAGGAGTTGAACATAGAGATGAAATTCTACCTAACGG
ATTTTCTAGCAATCATTCCGGAGGAATATTAGGTGGTATTAGTAACGGGGAAGAAATTATTGTACATGCAGCTTTTAAAC
CTACATCTAGTATTAAAATACCGGGAAAAACAATAGATACATTTGGAAAAAAAAGATTTATTATAACAAAAGGAAGACAT
GATCCTTGTGTAGGAATTCGAGCTGTTCCAATTGCAGAAGCAATGTTAGCAATTACATTAATGGACCATGTTTTACGTTT
CAAAGCTCAATGTGGAAAATAA

Upstream 100 bases:

>100_bases
TATAGATTAATATAATTAATTAATTATTTATTTTAAATAAATAAAATATTATAATAATAAAATAATATTTCTTTATTTCT
TGCAAACTATGAGGTAGAAA

Downstream 100 bases:

>100_bases
AATTTTAATATAATATAAATTACATTATTTCAACTAAAAAAAATATTTTATTTTTAAAAATTCTCCAAAATATATTTTAT
ATATATAAAAAATACTTATA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MPGNSIGKIFKVTTCGESHGPMLAGIIDGVPPGLSLNNKDIQYELNRRRPGFSKFTSQRREKDKVEIFSGIFKGITTGTS
IGIRIKNIDIRSQDYSEIKNLYRPNHADYTYEKKYGIRDYRGGGRSSARETAIRVAAGAIAKKYLKLQHNIKIRGYLSQI
GSIYCPFQSWEEVEKNPFFCSNSEKIKKIIHFIKKLKKSGNSVGAKITIIAKNVPIGLGEPVFDRLNAEIAHSIMSINAA
KSIEIGDGIHVAKQTGVEHRDEILPNGFSSNHSGGILGGISNGEEIIVHAAFKPTSSIKIPGKTIDTFGKKRFIITKGRH
DPCVGIRAVPIAEAMLAITLMDHVLRFKAQCGK

Sequences:

>Translated_353_residues
MPGNSIGKIFKVTTCGESHGPMLAGIIDGVPPGLSLNNKDIQYELNRRRPGFSKFTSQRREKDKVEIFSGIFKGITTGTS
IGIRIKNIDIRSQDYSEIKNLYRPNHADYTYEKKYGIRDYRGGGRSSARETAIRVAAGAIAKKYLKLQHNIKIRGYLSQI
GSIYCPFQSWEEVEKNPFFCSNSEKIKKIIHFIKKLKKSGNSVGAKITIIAKNVPIGLGEPVFDRLNAEIAHSIMSINAA
KSIEIGDGIHVAKQTGVEHRDEILPNGFSSNHSGGILGGISNGEEIIVHAAFKPTSSIKIPGKTIDTFGKKRFIITKGRH
DPCVGIRAVPIAEAMLAITLMDHVLRFKAQCGK
>Mature_352_residues
PGNSIGKIFKVTTCGESHGPMLAGIIDGVPPGLSLNNKDIQYELNRRRPGFSKFTSQRREKDKVEIFSGIFKGITTGTSI
GIRIKNIDIRSQDYSEIKNLYRPNHADYTYEKKYGIRDYRGGGRSSARETAIRVAAGAIAKKYLKLQHNIKIRGYLSQIG
SIYCPFQSWEEVEKNPFFCSNSEKIKKIIHFIKKLKKSGNSVGAKITIIAKNVPIGLGEPVFDRLNAEIAHSIMSINAAK
SIEIGDGIHVAKQTGVEHRDEILPNGFSSNHSGGILGGISNGEEIIVHAAFKPTSSIKIPGKTIDTFGKKRFIITKGRHD
PCVGIRAVPIAEAMLAITLMDHVLRFKAQCGK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=350, Percent_Identity=64, Blast_Score=466, Evalue=1e-133,
Organism=Saccharomyces cerevisiae, GI6321290, Length=370, Percent_Identity=44.0540540540541, Blast_Score=288, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_BUCCC (Q058B0)

Other databases:

- EMBL:   CP000263
- RefSeq:   YP_802632.1
- ProteinModelPortal:   Q058B0
- SMR:   Q058B0
- STRING:   Q058B0
- EnsemblBacteria:   EBBUCT00000001326
- GeneID:   4440765
- GenomeReviews:   CP000263_GR
- KEGG:   bcc:BCc_061
- eggNOG:   COG0082
- GeneTree:   EBGT00050000007958
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- ProtClustDB:   PRK05382
- BioCyc:   BAPH372461:BCC_061-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 38878; Mature: 38746

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGNSIGKIFKVTTCGESHGPMLAGIIDGVPPGLSLNNKDIQYELNRRRPGFSKFTSQRR
CCCCCCCCEEEEEECCCCCCCEEEHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHH
EKDKVEIFSGIFKGITTGTSIGIRIKNIDIRSQDYSEIKNLYRPNHADYTYEKKYGIRDY
HHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCHHHHHHHHCCCCCCCEEHHCCCCCCC
RGGGRSSARETAIRVAAGAIAKKYLKLQHNIKIRGYLSQIGSIYCPFQSWEEVEKNPFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCEECCCCCHHHHHCCCCEE
SNSEKIKKIIHFIKKLKKSGNSVGAKITIIAKNVPIGLGEPVFDRLNAEIAHSIMSINAA
CCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCC
KSIEIGDGIHVAKQTGVEHRDEILPNGFSSNHSGGILGGISNGEEIIVHAAFKPTSSIKI
CEEECCCCEEHHHHCCCHHHHHHCCCCCCCCCCCCEEECCCCCCEEEEEEEECCCCCEEE
PGKTIDTFGKKRFIITKGRHDPCVGIRAVPIAEAMLAITLMDHVLRFKAQCGK
CCCHHHHCCCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PGNSIGKIFKVTTCGESHGPMLAGIIDGVPPGLSLNNKDIQYELNRRRPGFSKFTSQRR
CCCCCCCEEEEEECCCCCCCEEEHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHH
EKDKVEIFSGIFKGITTGTSIGIRIKNIDIRSQDYSEIKNLYRPNHADYTYEKKYGIRDY
HHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCHHHHHHHHCCCCCCCEEHHCCCCCCC
RGGGRSSARETAIRVAAGAIAKKYLKLQHNIKIRGYLSQIGSIYCPFQSWEEVEKNPFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCEECCCCCHHHHHCCCCEE
SNSEKIKKIIHFIKKLKKSGNSVGAKITIIAKNVPIGLGEPVFDRLNAEIAHSIMSINAA
CCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCC
KSIEIGDGIHVAKQTGVEHRDEILPNGFSSNHSGGILGGISNGEEIIVHAAFKPTSSIKI
CEEECCCCEEHHHHCCCHHHHHHCCCCCCCCCCCCEEECCCCCCEEEEEEEECCCCCEEE
PGKTIDTFGKKRFIITKGRHDPCVGIRAVPIAEAMLAITLMDHVLRFKAQCGK
CCCHHHHCCCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA