Click here to switch to the map view.

The map label for this gene is dapA

Identifier: 116515002

GI number: 116515002

Start: 66878

End: 67771

Strand: Reverse

Name: dapA

Synonym: BCc_060

Alternate gene names: 116515002

Gene position: 67771-66878 (Counterclockwise)

Preceding gene: 116515003

Following gene: 116514997

Centisome position: 16.28

GC content: 25.28

Gene sequence:

>894_bases
ATGTTTAAAGGTAGCATTGTTGCTCTTATCACACCTATGGATATTAAAGGAAATATTTGTAAAAAAAGTTTAAAAAAATT
AGTTAAATACCATATTAAAAATAAAACAAATGCAATAATTTCAGTAGGTACTACAGGAGAATCAGCTACTCTAAATAAAA
ATGAACATACAAATGTTATTATGCATACATTAGAATATGCAGATGAAAAAATACCAATTATAGCTGGTACAGGATCTAAT
GCAACTTCAGAAAGTATTCTTCTAACTAAAAAACTTGAATTATCAGGTATTTCAGGATGTTTAAATATTACTCCGTATTA
TAATAAACCAACCCAAGAAGGTTTATATTTACATTTTAAATCTATTTCAGAAAGTACTGATTTACCTCAAATTTTATACA
ATGTACCACATCGAACAGGGTGTGATTTATTACCTCAAACAATAGCTAAATTAGCAAAATTTAAAAATATAATTGGATTA
AAAGATGCGTCTGGTGATTTATCTAGAGTTAATCAAATAAAATCATTAGTTAATAAAAATTTTATATTAATTAGTGGAGA
TGATACAACAGCTTTGGATTTTATCCAACTCGGAGGAAATGGAGTAATCTCAGTAACAGCAAATATTGCAGCTAGACATA
TATCAAAAATCTGTAAATTAGCTTTGGCTGGAAATTTTTATAAAGCTAGAAAAATAAATGAAAAATTGAAGATTTTACAT
AATCTTTTATTTAAAGAAACTAATCCAATACCTATTAAGTGGGCAGCTAAATATATAGGCCTTATAGAGACCGACAAAAT
TCGATTACCTATGACACAACTATTAGATAAAAATAAAAAAAATCTTAAAAAAATAATAAATTTACTACAATTAAACAAAA
ATAAATTTTTATAA

Upstream 100 bases:

>100_bases
TTATATACTAAAATAAATCTATAAAATATAGAAAAAAAATAATTTTACAATTTAAATTATAAAATTATTTAATTAATTCT
TATTTTAAAAGGAAAAAAAA

Downstream 100 bases:

>100_bases
AATAAATTTAATAAAACATATTATCTATATTTATATAGAGTATATTATACTATATAAAATATTTATTATTTTAAAAAAAA
TATATTTTATGCAATGATAA

Product: hypothetical protein

Products: NA

Alternate protein names: DHDPS

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MFKGSIVALITPMDIKGNICKKSLKKLVKYHIKNKTNAIISVGTTGESATLNKNEHTNVIMHTLEYADEKIPIIAGTGSN
ATSESILLTKKLELSGISGCLNITPYYNKPTQEGLYLHFKSISESTDLPQILYNVPHRTGCDLLPQTIAKLAKFKNIIGL
KDASGDLSRVNQIKSLVNKNFILISGDDTTALDFIQLGGNGVISVTANIAARHISKICKLALAGNFYKARKINEKLKILH
NLLFKETNPIPIKWAAKYIGLIETDKIRLPMTQLLDKNKKNLKKIINLLQLNKNKFL

Sequences:

>Translated_297_residues
MFKGSIVALITPMDIKGNICKKSLKKLVKYHIKNKTNAIISVGTTGESATLNKNEHTNVIMHTLEYADEKIPIIAGTGSN
ATSESILLTKKLELSGISGCLNITPYYNKPTQEGLYLHFKSISESTDLPQILYNVPHRTGCDLLPQTIAKLAKFKNIIGL
KDASGDLSRVNQIKSLVNKNFILISGDDTTALDFIQLGGNGVISVTANIAARHISKICKLALAGNFYKARKINEKLKILH
NLLFKETNPIPIKWAAKYIGLIETDKIRLPMTQLLDKNKKNLKKIINLLQLNKNKFL
>Mature_297_residues
MFKGSIVALITPMDIKGNICKKSLKKLVKYHIKNKTNAIISVGTTGESATLNKNEHTNVIMHTLEYADEKIPIIAGTGSN
ATSESILLTKKLELSGISGCLNITPYYNKPTQEGLYLHFKSISESTDLPQILYNVPHRTGCDLLPQTIAKLAKFKNIIGL
KDASGDLSRVNQIKSLVNKNFILISGDDTTALDFIQLGGNGVISVTANIAARHISKICKLALAGNFYKARKINEKLKILH
NLLFKETNPIPIKWAAKYIGLIETDKIRLPMTQLLDKNKKNLKKIINLLQLNKNKFL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family

Homologues:

Organism=Homo sapiens, GI31543060, Length=271, Percent_Identity=23.2472324723247, Blast_Score=92, Evalue=6e-19,
Organism=Escherichia coli, GI1788823, Length=283, Percent_Identity=63.9575971731449, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI87082415, Length=270, Percent_Identity=30.7407407407407, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786463, Length=243, Percent_Identity=28.3950617283951, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789620, Length=294, Percent_Identity=27.2108843537415, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPA_BUCCC (Q058B1)

Other databases:

- EMBL:   CP000263
- RefSeq:   YP_802631.1
- ProteinModelPortal:   Q058B1
- SMR:   Q058B1
- STRING:   Q058B1
- EnsemblBacteria:   EBBUCT00000001387
- GeneID:   4440764
- GenomeReviews:   CP000263_GR
- KEGG:   bcc:BCc_060
- eggNOG:   COG0329
- GeneTree:   EBGT00050000008107
- HOGENOM:   HBG358848
- OMA:   GMYRHFK
- BioCyc:   BAPH372461:BCC_060-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00418
- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR12128
- PRINTS:   PR00146
- TIGRFAMs:   TIGR00674

Pfam domain/function: PF00701 DHDPS

EC number: =4.2.1.52

Molecular weight: Translated: 32906; Mature: 32906

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: PS00665 DHDPS_1; PS00666 DHDPS_2

Important sites: ACT_SITE 161-161 BINDING 106-106

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKGSIVALITPMDIKGNICKKSLKKLVKYHIKNKTNAIISVGTTGESATLNKNEHTNVI
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHH
MHTLEYADEKIPIIAGTGSNATSESILLTKKLELSGISGCLNITPYYNKPTQEGLYLHFK
HHHHHHCCCCCCEEEECCCCCCCCEEEEEEEECCCCCCCEEECCCCCCCCCCCCEEEEEE
SISESTDLPQILYNVPHRTGCDLLPQTIAKLAKFKNIIGLKDASGDLSRVNQIKSLVNKN
CCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC
FILISGDDTTALDFIQLGGNGVISVTANIAARHISKICKLALAGNFYKARKINEKLKILH
EEEEECCCCCEEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
NLLFKETNPIPIKWAAKYIGLIETDKIRLPMTQLLDKNKKNLKKIINLLQLNKNKFL
HHHHCCCCCCCEEEHHHHHCEEECCCEECCHHHHHCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MFKGSIVALITPMDIKGNICKKSLKKLVKYHIKNKTNAIISVGTTGESATLNKNEHTNVI
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHH
MHTLEYADEKIPIIAGTGSNATSESILLTKKLELSGISGCLNITPYYNKPTQEGLYLHFK
HHHHHHCCCCCCEEEECCCCCCCCEEEEEEEECCCCCCCEEECCCCCCCCCCCCEEEEEE
SISESTDLPQILYNVPHRTGCDLLPQTIAKLAKFKNIIGLKDASGDLSRVNQIKSLVNKN
CCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC
FILISGDDTTALDFIQLGGNGVISVTANIAARHISKICKLALAGNFYKARKINEKLKILH
EEEEECCCCCEEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
NLLFKETNPIPIKWAAKYIGLIETDKIRLPMTQLLDKNKKNLKKIINLLQLNKNKFL
HHHHCCCCCCCEEEHHHHHCEEECCCEECCHHHHHCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA