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The map label for this gene is dnaA

Identifier: 116514954

GI number: 116514954

Start: 5647

End: 6960

Strand: Reverse

Name: dnaA

Synonym: BCc_004

Alternate gene names: 116514954

Gene position: 6960-5647 (Counterclockwise)

Preceding gene: 116514962

Following gene: 116514953

Centisome position: 1.67

GC content: 18.34

Gene sequence:

>1314_bases
ATGATATTTCCAATATGGAAAAAATGTTTAATACAATTACAAATAAAGTTATCACCGGTAGAATTTAGTTTATGGATTTT
ACCATTAAAAGTAACTATTAAAAATAATATAATTTATATATACACTCCTAATCTATTTATATTTAGGTGGATTAAAAAAA
AATATGTAAATATTTTTAAAAAAATATTATATAAAATATGCAGTAATAATCCACCAAAAATTATTATTAATATAGAAAAA
AAAAAACTAGAAAAAAAAAAATGTATATACAAAAAAAAAAATATTCAAATATATTTACATTCAGAAATCAATAAAAAATA
TCAATTTCATAATTTTATTCAAGGTCAATCAAATCAACTAGCTTACTATTCTTCTTATAAATTTACAAAAAATTTAAAAA
ATTTTTATAATCCATTATTTTTATATGGTAATACTGGTCTTGGAAAAACTCATTTACTACACGCAATTGGTAATAAATTT
TTAATAAAAAATAAAAAAAAAAAAGTAATTTATATACACTCAGAAAATTTTATTCAAAATATGGTAAATTCATTAAAAAA
TAATTCTATAGATAAATTCAAAAATTACTATCGATCTATTGATGTACTTTTATTAGATGATATTCAGTTTTTTTCTAATA
AAAAGAAATCACAAGAAGAATTATTCAATACATTTAATACCTTATTTAATAAACAACAAAAAATTGTATTAACAGCTGAT
TGTTATCCTGAATATATTTCTGGTATTACTGAACAATTAAAATCAAGATTTAAATGGGGGTTAACAATTTCAATAAATCC
TCCAGAATTAAAAACTAGAATTAAAATTTTATTGCATAAAGCATATGAAAATAAAATTCTTCTATCTTATGAAGTAGCTA
AATATATTGCAAAAAAAATATTTTCTAATGTAAGAGAGTTAGAGGGTATTTTAAAAAAAATACAAATATTATCTATATTA
AATAAAGAAAAGATAACTATTAATTTAGTAAAAAAAATTTTAAATAAAATAAAAAAAAAGAAAAAAAACATAAATATTAT
ATATATTCAAAAAATTGTTGCTAAATATTTTAATATTAGAATATCTGATATGATCTCTCAAAAAAGATCTCAATCAATTG
TACATCCTAGACAAATAGCTATGACACTAGCTAAAAAACTAACACATTATAGCTTTTCAGAAATTGGAACAGCATTTGGA
AAAAAAGATCATACTACTGTTTTATATGCTTATAAAAAAATAAATCAACTTAAAAAAAAAAAAACAGAAATTTATTCTGA
TTTTATATATCTCTTTAACCAATTAAATGCATAA

Upstream 100 bases:

>100_bases
TATATTATTTATATTTATTAAAAATACAATATTAATAAATCAAATTTAATATGTTTATTAATTATTATTAATAATTTATT
ATATTATGGATATTTAATAT

Downstream 100 bases:

>100_bases
AATTTATGGAATTTAAAATTAAAAAAAATGATTTTTTTAACTCATTTAAAAAAATGAATAGAATTATTACAAAAAATCCA
ATATTTCCAATATTAGAAAA

Product: DnaA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MIFPIWKKCLIQLQIKLSPVEFSLWILPLKVTIKNNIIYIYTPNLFIFRWIKKKYVNIFKKILYKICSNNPPKIIINIEK
KKLEKKKCIYKKKNIQIYLHSEINKKYQFHNFIQGQSNQLAYYSSYKFTKNLKNFYNPLFLYGNTGLGKTHLLHAIGNKF
LIKNKKKKVIYIHSENFIQNMVNSLKNNSIDKFKNYYRSIDVLLLDDIQFFSNKKKSQEELFNTFNTLFNKQQKIVLTAD
CYPEYISGITEQLKSRFKWGLTISINPPELKTRIKILLHKAYENKILLSYEVAKYIAKKIFSNVRELEGILKKIQILSIL
NKEKITINLVKKILNKIKKKKKNINIIYIQKIVAKYFNIRISDMISQKRSQSIVHPRQIAMTLAKKLTHYSFSEIGTAFG
KKDHTTVLYAYKKINQLKKKKTEIYSDFIYLFNQLNA

Sequences:

>Translated_437_residues
MIFPIWKKCLIQLQIKLSPVEFSLWILPLKVTIKNNIIYIYTPNLFIFRWIKKKYVNIFKKILYKICSNNPPKIIINIEK
KKLEKKKCIYKKKNIQIYLHSEINKKYQFHNFIQGQSNQLAYYSSYKFTKNLKNFYNPLFLYGNTGLGKTHLLHAIGNKF
LIKNKKKKVIYIHSENFIQNMVNSLKNNSIDKFKNYYRSIDVLLLDDIQFFSNKKKSQEELFNTFNTLFNKQQKIVLTAD
CYPEYISGITEQLKSRFKWGLTISINPPELKTRIKILLHKAYENKILLSYEVAKYIAKKIFSNVRELEGILKKIQILSIL
NKEKITINLVKKILNKIKKKKKNINIIYIQKIVAKYFNIRISDMISQKRSQSIVHPRQIAMTLAKKLTHYSFSEIGTAFG
KKDHTTVLYAYKKINQLKKKKTEIYSDFIYLFNQLNA
>Mature_437_residues
MIFPIWKKCLIQLQIKLSPVEFSLWILPLKVTIKNNIIYIYTPNLFIFRWIKKKYVNIFKKILYKICSNNPPKIIINIEK
KKLEKKKCIYKKKNIQIYLHSEINKKYQFHNFIQGQSNQLAYYSSYKFTKNLKNFYNPLFLYGNTGLGKTHLLHAIGNKF
LIKNKKKKVIYIHSENFIQNMVNSLKNNSIDKFKNYYRSIDVLLLDDIQFFSNKKKSQEELFNTFNTLFNKQQKIVLTAD
CYPEYISGITEQLKSRFKWGLTISINPPELKTRIKILLHKAYENKILLSYEVAKYIAKKIFSNVRELEGILKKIQILSIL
NKEKITINLVKKILNKIKKKKKNINIIYIQKIVAKYFNIRISDMISQKRSQSIVHPRQIAMTLAKKLTHYSFSEIGTAFG
KKDHTTVLYAYKKINQLKKKKTEIYSDFIYLFNQLNA

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family

Homologues:

Organism=Escherichia coli, GI2367267, Length=467, Percent_Identity=43.254817987152, Blast_Score=438, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DNAA_BUCCC (Q058F9)

Other databases:

- EMBL:   CP000263
- RefSeq:   YP_802583.1
- ProteinModelPortal:   Q058F9
- STRING:   Q058F9
- EnsemblBacteria:   EBBUCT00000001433
- GeneID:   4440644
- GenomeReviews:   CP000263_GR
- KEGG:   bcc:BCc_004
- eggNOG:   COG0593
- GeneTree:   EBGT00050000008033
- HOGENOM:   HBG695666
- OMA:   DEVAFLI
- BioCyc:   BAPH372461:BCC_004-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00377
- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921
- Gene3D:   G3DSA:1.10.1750.10
- PRINTS:   PR00051
- SMART:   SM00382
- SMART:   SM00760
- TIGRFAMs:   TIGR00362

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C; SSF48295 Trp_repress_rep

EC number: NA

Molecular weight: Translated: 51984; Mature: 51984

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFPIWKKCLIQLQIKLSPVEFSLWILPLKVTIKNNIIYIYTPNLFIFRWIKKKYVNIFK
CCCHHHHHHHHEEEEEECCEEEEEEEEEEEEEEECCEEEEECCCHHHHHHHHHHHHHHHH
KILYKICSNNPPKIIINIEKKKLEKKKCIYKKKNIQIYLHSEINKKYQFHNFIQGQSNQL
HHHHHHHCCCCCEEEEEEHHHHHHHHHHHHEECCEEEEEECCCCCHHHHHHHHCCCCCCE
AYYSSYKFTKNLKNFYNPLFLYGNTGLGKTHLLHAIGNKFLIKNKKKKVIYIHSENFIQN
EEEECCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCEEEECCCCEEEEEECHHHHHH
MVNSLKNNSIDKFKNYYRSIDVLLLDDIQFFSNKKKSQEELFNTFNTLFNKQQKIVLTAD
HHHHHCCCCHHHHHHHHHHHHEEEEHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEC
CYPEYISGITEQLKSRFKWGLTISINPPELKTRIKILLHKAYENKILLSYEVAKYIAKKI
CCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHH
FSNVRELEGILKKIQILSILNKEKITINLVKKILNKIKKKKKNINIIYIQKIVAKYFNIR
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCH
ISDMISQKRSQSIVHPRQIAMTLAKKLTHYSFSEIGTAFGKKDHTTVLYAYKKINQLKKK
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEHHHHHHHHHHHH
KTEIYSDFIYLFNQLNA
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIFPIWKKCLIQLQIKLSPVEFSLWILPLKVTIKNNIIYIYTPNLFIFRWIKKKYVNIFK
CCCHHHHHHHHEEEEEECCEEEEEEEEEEEEEEECCEEEEECCCHHHHHHHHHHHHHHHH
KILYKICSNNPPKIIINIEKKKLEKKKCIYKKKNIQIYLHSEINKKYQFHNFIQGQSNQL
HHHHHHHCCCCCEEEEEEHHHHHHHHHHHHEECCEEEEEECCCCCHHHHHHHHCCCCCCE
AYYSSYKFTKNLKNFYNPLFLYGNTGLGKTHLLHAIGNKFLIKNKKKKVIYIHSENFIQN
EEEECCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCEEEECCCCEEEEEECHHHHHH
MVNSLKNNSIDKFKNYYRSIDVLLLDDIQFFSNKKKSQEELFNTFNTLFNKQQKIVLTAD
HHHHHCCCCHHHHHHHHHHHHEEEEHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEC
CYPEYISGITEQLKSRFKWGLTISINPPELKTRIKILLHKAYENKILLSYEVAKYIAKKI
CCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHH
FSNVRELEGILKKIQILSILNKEKITINLVKKILNKIKKKKKNINIIYIQKIVAKYFNIR
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCH
ISDMISQKRSQSIVHPRQIAMTLAKKLTHYSFSEIGTAFGKKDHTTVLYAYKKINQLKKK
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEHHHHHHHHHHHH
KTEIYSDFIYLFNQLNA
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA