| Definition | Leptospira borgpetersenii serovar Hardjo-bovis L550 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008508 |
| Length | 3,614,446 |
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The map label for this gene is clpA-1 [H]
Identifier: 116328481
GI number: 116328481
Start: 2129509
End: 2132088
Strand: Reverse
Name: clpA-1 [H]
Synonym: LBL_1829
Alternate gene names: 116328481
Gene position: 2132088-2129509 (Counterclockwise)
Preceding gene: 116328485
Following gene: 116328480
Centisome position: 58.99
GC content: 43.68
Gene sequence:
>2580_bases ATGAAACTAGATAAACTCACTGCAAAATTAAATGAAGCGTTGCATAACGCACAAGTTTCTGCCGAGAAGTCGGGAAATCC GGAAATCAGTGAAGAACACATTCTTAGAGAAGTTTTGGTCCAGACCGACGGACTTGTCCCACTTTTGATTTCAAAACTTA ACCTAAATCCGAAATCCTTTCTCGAAAAAACCGAAGACGCACTGAGGCGGCTTCCGAAAGTCGGAGGAACTTCTTCCGCT GATGTGGGATTCTCACGTTCCGCAGTTTCTCTTTTGAAAACTGCGGATGAAATCCGTAGGGAACTAAAAGACGAGTATTT ATCAACGGACCATGTAATTCTCGGGCTTATGAAAAATGGAGTCGGACCGTTGAAGGAGGAATTTTTAAAACTAGGATTAG AATATTCTAAATTACTTAATATTACTTTGGAGAATAGAAAGGGAAAGGCAATCATGGACGATTCACCGGAAGGAAAAATG GACGCTCTTGCAAAGTATGCAAAAAATCTTAACGACCTCGCCAAACAGGGAAAACTTGATCCTGTTATCGGAAGAGACGA AGAGATAAGAAGGACGATTCAAGTCCTCTCCAGAAGAACGAAAAATAACCCGGTTCTTATCGGAGAACCCGGAGTAGGTA AGACTGCGATCGTAGAAGGACTTGCGAACAAGATCGTACAAGGGGAGGTTCCGGAAGGAATCAGGAATAAAACTCTTTAT ACCCTGGACCTAGGTTCCATGATCGCGGGAGCCAAATACAGAGGGGAGTTTGAAGACAGATTGAAAGCCCTTCTCGACGA GGTTAAGGCTTCGGACGGCGAGGTTATTTTATTTATAGACGAAATTCATACTCTTGTAGGCGCCGGCGCAACGGAAGGTG CATTAGACGCTTCTAATATGCTGAAGCCGATGCTTGCCAGAGGAGAACTCCGATGTATCGGTGCTACCACTCTGAAAGAA TATCAGAAATACATTGAAAAGGACGCCGCATTGGAAAGAAGGTTTCAACCCGTTTACGTTAAAGAACCTTCCGTCGAGGA AACGGTTACGATCTTAAGAGGACTCAAAGGACGTTACGAGCTCCATCATGGAATTCGAATTCTTGATTCCGCGTTGATCG CGGCGGCTACCCTTTCCAATCGGTATATCGTCGACCGTTTCCTTCCCGATAAAGCGGTGGATTTGATCGACGAGGCGTCT TCTAAGATGAGGATCGAGATCGACTCCATGCCGGAAGAATTGGATCGCGCGAGTAAACGGATTCAATCCTTAAAAATCGA AAGAGAGGCGTTGAAAAAAGAACAGGATCCCGCTTCGAAAGAAAGATTGAAATCACTCGAAAAGGATCTTGCGGAACAAG AGCAGAATTTTCAGACTTTGAAGGCGAGATGGGATTTGGAAAAATCCAAAATCTTACGATTGAAACAAATTAAGGAAGAG ATCGAAAAGTATAAAAACTTAGAAGCGGACGCGGAAAGAAAAGGAGAAATCAATCGAGTCGCCGAAATCCGCTACGGAAA ACTAGTCGATTTACAAAAAGAATTCGAAGCCGCAAACGAAGAATTAAAAAAACAAGAAGGGGCCTCTCGGCTTTTGAAAG AAGAAGTCTCCGAAGAAGACATTGCGAACATCGTTTCTCGTTGGACCGGGATTCCCGTATCCAAAATGCTTCAAGGGGAA AGAGCAAAACTTCTTTTGATGGAAGACGCTTTGAAGACAAGGGTTATCGGCCAGGATCACGCTCTCAAACTTGTATCTGA AGCGGTACAAAGATCAAGGGCTGGGATTGCGGATCCGAATCGACCGATTGGAACTTTCTTATTCCTGGGACCTACGGGAG TTGGAAAAACGGAAACCGCAAAGGCTCTCGCCGAATTCTTGTTCGACGATGCAAATGCGATGCATCGAATCGATATGAGC GAGTATATGGAAGCGCATTCTGTTGCGCGACTTATCGGAGCGCCGCCCGGTTATGTGGGATACGACGAAGGGGGACAACT CACCGAAGCGGTGAGAAGAAGGCCATATTCTCTGATTCTATTCGACGAAGTTGAAAAAGCGAACCCGGATGTATTCAACA TTTTTCTTCAAATTTTGGACGAAGGTAGATTAACCGATGGAAAGGGGCGTAACGTTGATTTCAAGAACACGGTGATCATT CTCACTTCCAATATCGGATCGGACATTTTGGGTTCTTCCGAATATAGCGCCGAAGAAAAAGAAAGATTAGTCGAAGAACG TTTGAAAAAACAATTCAAACCCGAATTCTTAAACCGAATCGACGAAGTGATTCTATTTCATTCAATTTCAAATTCCGTGA TTCACAAAATTGCAGACATTCAGTTGGAGGCGTTGAAACAAAAGGCGAAGGAGAACGGTTTGGATGTTCAGTTTACAGAC GAATTGAAGGACTATGTTTCTAGAGCAGGTTTTGATGCCGAATATGGAGCTAGACCTCTGAAACGTTTGATCCAAAGAGA AGTTGGCAACTCTCTCAGTCGCTACATTTTAAATGGTAAATTTTCGGACGGACAAAAAGTGACTGTGGATTATAGACAGG GAAAAGTGATCGTAATTTAA
Upstream 100 bases:
>100_bases GGGTTGCCTATTAAAATAAGAGTGTCAATATGGCAGAAAAATTTGAGATTTTTAGTATCAGAGAGTCTAAATTCTAAATG AAAAGTTGGAGAATTAGGGA
Downstream 100 bases:
>100_bases ACTGGGGCCGATTGTTTATTGTGGAACGTCGAACCCGTCTCAAAACATCAAAATGTAGAAACTACTACATTTTTTATACG ATAAACAAGTAGGTTCTGAG
Product: endopeptidase Clp, ATP-dependent proteolytic subunit
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 859; Mature: 859
Protein sequence:
>859_residues MKLDKLTAKLNEALHNAQVSAEKSGNPEISEEHILREVLVQTDGLVPLLISKLNLNPKSFLEKTEDALRRLPKVGGTSSA DVGFSRSAVSLLKTADEIRRELKDEYLSTDHVILGLMKNGVGPLKEEFLKLGLEYSKLLNITLENRKGKAIMDDSPEGKM DALAKYAKNLNDLAKQGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLANKIVQGEVPEGIRNKTLY TLDLGSMIAGAKYRGEFEDRLKALLDEVKASDGEVILFIDEIHTLVGAGATEGALDASNMLKPMLARGELRCIGATTLKE YQKYIEKDAALERRFQPVYVKEPSVEETVTILRGLKGRYELHHGIRILDSALIAAATLSNRYIVDRFLPDKAVDLIDEAS SKMRIEIDSMPEELDRASKRIQSLKIEREALKKEQDPASKERLKSLEKDLAEQEQNFQTLKARWDLEKSKILRLKQIKEE IEKYKNLEADAERKGEINRVAEIRYGKLVDLQKEFEAANEELKKQEGASRLLKEEVSEEDIANIVSRWTGIPVSKMLQGE RAKLLLMEDALKTRVIGQDHALKLVSEAVQRSRAGIADPNRPIGTFLFLGPTGVGKTETAKALAEFLFDDANAMHRIDMS EYMEAHSVARLIGAPPGYVGYDEGGQLTEAVRRRPYSLILFDEVEKANPDVFNIFLQILDEGRLTDGKGRNVDFKNTVII LTSNIGSDILGSSEYSAEEKERLVEERLKKQFKPEFLNRIDEVILFHSISNSVIHKIADIQLEALKQKAKENGLDVQFTD ELKDYVSRAGFDAEYGARPLKRLIQREVGNSLSRYILNGKFSDGQKVTVDYRQGKVIVI
Sequences:
>Translated_859_residues MKLDKLTAKLNEALHNAQVSAEKSGNPEISEEHILREVLVQTDGLVPLLISKLNLNPKSFLEKTEDALRRLPKVGGTSSA DVGFSRSAVSLLKTADEIRRELKDEYLSTDHVILGLMKNGVGPLKEEFLKLGLEYSKLLNITLENRKGKAIMDDSPEGKM DALAKYAKNLNDLAKQGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLANKIVQGEVPEGIRNKTLY TLDLGSMIAGAKYRGEFEDRLKALLDEVKASDGEVILFIDEIHTLVGAGATEGALDASNMLKPMLARGELRCIGATTLKE YQKYIEKDAALERRFQPVYVKEPSVEETVTILRGLKGRYELHHGIRILDSALIAAATLSNRYIVDRFLPDKAVDLIDEAS SKMRIEIDSMPEELDRASKRIQSLKIEREALKKEQDPASKERLKSLEKDLAEQEQNFQTLKARWDLEKSKILRLKQIKEE IEKYKNLEADAERKGEINRVAEIRYGKLVDLQKEFEAANEELKKQEGASRLLKEEVSEEDIANIVSRWTGIPVSKMLQGE RAKLLLMEDALKTRVIGQDHALKLVSEAVQRSRAGIADPNRPIGTFLFLGPTGVGKTETAKALAEFLFDDANAMHRIDMS EYMEAHSVARLIGAPPGYVGYDEGGQLTEAVRRRPYSLILFDEVEKANPDVFNIFLQILDEGRLTDGKGRNVDFKNTVII LTSNIGSDILGSSEYSAEEKERLVEERLKKQFKPEFLNRIDEVILFHSISNSVIHKIADIQLEALKQKAKENGLDVQFTD ELKDYVSRAGFDAEYGARPLKRLIQREVGNSLSRYILNGKFSDGQKVTVDYRQGKVIVI >Mature_859_residues MKLDKLTAKLNEALHNAQVSAEKSGNPEISEEHILREVLVQTDGLVPLLISKLNLNPKSFLEKTEDALRRLPKVGGTSSA DVGFSRSAVSLLKTADEIRRELKDEYLSTDHVILGLMKNGVGPLKEEFLKLGLEYSKLLNITLENRKGKAIMDDSPEGKM DALAKYAKNLNDLAKQGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLANKIVQGEVPEGIRNKTLY TLDLGSMIAGAKYRGEFEDRLKALLDEVKASDGEVILFIDEIHTLVGAGATEGALDASNMLKPMLARGELRCIGATTLKE YQKYIEKDAALERRFQPVYVKEPSVEETVTILRGLKGRYELHHGIRILDSALIAAATLSNRYIVDRFLPDKAVDLIDEAS SKMRIEIDSMPEELDRASKRIQSLKIEREALKKEQDPASKERLKSLEKDLAEQEQNFQTLKARWDLEKSKILRLKQIKEE IEKYKNLEADAERKGEINRVAEIRYGKLVDLQKEFEAANEELKKQEGASRLLKEEVSEEDIANIVSRWTGIPVSKMLQGE RAKLLLMEDALKTRVIGQDHALKLVSEAVQRSRAGIADPNRPIGTFLFLGPTGVGKTETAKALAEFLFDDANAMHRIDMS EYMEAHSVARLIGAPPGYVGYDEGGQLTEAVRRRPYSLILFDEVEKANPDVFNIFLQILDEGRLTDGKGRNVDFKNTVII LTSNIGSDILGSSEYSAEEKERLVEERLKKQFKPEFLNRIDEVILFHSISNSVIHKIADIQLEALKQKAKENGLDVQFTD ELKDYVSRAGFDAEYGARPLKRLIQREVGNSLSRYILNGKFSDGQKVTVDYRQGKVIVI
Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase
COG id: COG0542
COG function: function code O; ATPases with chaperone activity, ATP-binding subunit
Gene ontology:
Cell location: Cytoplasm (Probable) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the clpA/clpB family [H]
Homologues:
Organism=Homo sapiens, GI13540606, Length=299, Percent_Identity=37.7926421404682, Blast_Score=203, Evalue=6e-52, Organism=Escherichia coli, GI1788943, Length=864, Percent_Identity=53.125, Blast_Score=902, Evalue=0.0, Organism=Escherichia coli, GI1787109, Length=270, Percent_Identity=52.2222222222222, Blast_Score=285, Evalue=1e-77, Organism=Saccharomyces cerevisiae, GI6320464, Length=717, Percent_Identity=50.9065550906555, Blast_Score=752, Evalue=0.0, Organism=Saccharomyces cerevisiae, GI6323002, Length=856, Percent_Identity=41.2383177570093, Blast_Score=650, Evalue=0.0,
Paralogues:
None
Copy number: 560 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR013093 - InterPro: IPR003959 - InterPro: IPR018368 - InterPro: IPR017730 - InterPro: IPR001270 - InterPro: IPR019489 - InterPro: IPR004176 - InterPro: IPR023150 [H]
Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]
EC number: NA
Molecular weight: Translated: 96324; Mature: 96324
Theoretical pI: Translated: 6.24; Mature: 6.24
Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 1.7 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 1.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKLDKLTAKLNEALHNAQVSAEKSGNPEISEEHILREVLVQTDGLVPLLISKLNLNPKSF CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHH LEKTEDALRRLPKVGGTSSADVGFSRSAVSLLKTADEIRRELKDEYLSTDHVILGLMKNG HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC VGPLKEEFLKLGLEYSKLLNITLENRKGKAIMDDSPEGKMDALAKYAKNLNDLAKQGKLD CCHHHHHHHHHCCCHHHHEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHHHHHHCCCCC PVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLANKIVQGEVPEGIRNKTLY CCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEE TLDLGSMIAGAKYRGEFEDRLKALLDEVKASDGEVILFIDEIHTLVGAGATEGALDASNM EEEHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCCCHHHH LKPMLARGELRCIGATTLKEYQKYIEKDAALERRFQPVYVKEPSVEETVTILRGLKGRYE HHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHCCCHHH LHHGIRILDSALIAAATLSNRYIVDRFLPDKAVDLIDEASSKMRIEIDSMPEELDRASKR HHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHH IQSLKIEREALKKEQDPASKERLKSLEKDLAEQEQNFQTLKARWDLEKSKILRLKQIKEE HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH IEKYKNLEADAERKGEINRVAEIRYGKLVDLQKEFEAANEELKKQEGASRLLKEEVSEED HHHHHCCCCCHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH IANIVSRWTGIPVSKMLQGERAKLLLMEDALKTRVIGQDHALKLVSEAVQRSRAGIADPN HHHHHHHHCCCCHHHHHCCCCHHEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCC RPIGTFLFLGPTGVGKTETAKALAEFLFDDANAMHRIDMSEYMEAHSVARLIGAPPGYVG CCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCC YDEGGQLTEAVRRRPYSLILFDEVEKANPDVFNIFLQILDEGRLTDGKGRNVDFKNTVII CCCCCHHHHHHHHCCCEEEEEECHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEE LTSNIGSDILGSSEYSAEEKERLVEERLKKQFKPEFLNRIDEVILFHSISNSVIHKIADI EECCCCCHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH QLEALKQKAKENGLDVQFTDELKDYVSRAGFDAEYGARPLKRLIQREVGNSLSRYILNGK HHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCC FSDGQKVTVDYRQGKVIVI CCCCCEEEEEECCCCEEEC >Mature Secondary Structure MKLDKLTAKLNEALHNAQVSAEKSGNPEISEEHILREVLVQTDGLVPLLISKLNLNPKSF CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHH LEKTEDALRRLPKVGGTSSADVGFSRSAVSLLKTADEIRRELKDEYLSTDHVILGLMKNG HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC VGPLKEEFLKLGLEYSKLLNITLENRKGKAIMDDSPEGKMDALAKYAKNLNDLAKQGKLD CCHHHHHHHHHCCCHHHHEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHHHHHHCCCCC PVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLANKIVQGEVPEGIRNKTLY CCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEE TLDLGSMIAGAKYRGEFEDRLKALLDEVKASDGEVILFIDEIHTLVGAGATEGALDASNM EEEHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCCCHHHH LKPMLARGELRCIGATTLKEYQKYIEKDAALERRFQPVYVKEPSVEETVTILRGLKGRYE HHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHCCCHHH LHHGIRILDSALIAAATLSNRYIVDRFLPDKAVDLIDEASSKMRIEIDSMPEELDRASKR HHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHH IQSLKIEREALKKEQDPASKERLKSLEKDLAEQEQNFQTLKARWDLEKSKILRLKQIKEE HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH IEKYKNLEADAERKGEINRVAEIRYGKLVDLQKEFEAANEELKKQEGASRLLKEEVSEED HHHHHCCCCCHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH IANIVSRWTGIPVSKMLQGERAKLLLMEDALKTRVIGQDHALKLVSEAVQRSRAGIADPN HHHHHHHHCCCCHHHHHCCCCHHEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCC RPIGTFLFLGPTGVGKTETAKALAEFLFDDANAMHRIDMSEYMEAHSVARLIGAPPGYVG CCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCC YDEGGQLTEAVRRRPYSLILFDEVEKANPDVFNIFLQILDEGRLTDGKGRNVDFKNTVII CCCCCHHHHHHHHCCCEEEEEECHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEE LTSNIGSDILGSSEYSAEEKERLVEERLKKQFKPEFLNRIDEVILFHSISNSVIHKIADI EECCCCCHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH QLEALKQKAKENGLDVQFTDELKDYVSRAGFDAEYGARPLKRLIQREVGNSLSRYILNGK HHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCC FSDGQKVTVDYRQGKVIVI CCCCCEEEEEECCCCEEEC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA