Click here to switch to the map view.

The map label for this gene is cyaB [H]

Identifier: 116328480

GI number: 116328480

Start: 2125696

End: 2127024

Strand: Reverse

Name: cyaB [H]

Synonym: LBL_1826

Alternate gene names: 116328480

Gene position: 2127024-2125696 (Counterclockwise)

Preceding gene: 116328481

Following gene: 116328479

Centisome position: 58.85

GC content: 44.47

Gene sequence:

>1329_bases
ATGGCTCGGGAAATTCGCCCGGATCTTGTGTTGATCGATATTGTTCTCGGTACCGGGTTTATAGACGGAGTTGAAACCGT
CGTCAAGTTAAAAGAGATACTGGATGTTCCGGTAATCTATGTGACCGCAGATAGCGACGAAGCTACTCTGAAAAGGGCGC
GTGTAACGGAACCGTTCGGATATATTCTCAAACCGATAAATGTTCGAGAACTTGAGATCACGGTTGAGATGTGTCTCTAT
CGGCATAAGATGGAGAAACGTTTTCGTGAAGATGCAAGCTGGTTGACTACCACTTTGAGTTCGATAGGAGACGGAGTGAT
CGCTACCGATTCGATTTCCAGAGTTAAGTTTTTAAATCCGGTTGCGGAAGCCCTTTTAGGAATGAATGAAAAAGCGGTTC
GAGGTAGGATAGTGGATGATGTAATGCATTTAAGAGACATGAAGGGTGCAATCATTCAAAATTTAGTTTCTTATGCTACG
ATCAATCAGTCGCCCGCCGTTTTTGAACACGTGATTCTTTCCGATTCCAATGGACGAAGTACTCCCGTTATTTGTACGGT
AGCTCCGATTCATGATACGAATGGAACTTCTCACGGTTGTGTTTTCACCTTACGGGATATAAGCGAACTGTATGCTAAAT
CGCAAGAACTCAGCAAACGAATGGAGGACGTGGAACAGGCAAAACGTCTGTTGGAAAAATACTTTCCTGAAAACTTGGTG
GATTACCTCGTCGATGAAAAACGGCAAATGGAACTTGAAGGGAAGAATGTTCAAGCTACGATGTTATTTTGCGACGTTCG
AAATTCCACGGGGATCGCCGAAAGGTTAAATCCGGATGAGTTTGCGGCTTTTTTGAGCGAGCTGTTTACGGGGCTTATGG
ATATCACGTACGCGAATGGAGGCTCGGTAAATAAATTACTCGGAGACGGACTCTTGATCACTTTTGGCTGTCCTTTCCCA
GAAGAAGAGGATACGATCAATTGCGTTCGATTGGCTCTGCAAATTCGAGAGTATCTACGCGCGTTCAATGATAACCGAAA
TCCAAAAATTCTCACTCCCGTGGCGATGGGAATTGGAATTTCGACCGGGAATGTGTTTGCGGGAAACGTCGGTTCGTCGC
GACACATGGAATACACCGTGTTAGGCGATGCGGTCAATACCGCGAGCAGACTGGAAGCTCTTACAAAAACGACGGGTCAT
GATATACTTTTGGATTCTTTTACTTCCGATTTTATTCGTCATGAAATCAACGTCGAACCAATCGGTACATTTTTGTTACG
AGGTAAAAAGGAACCGCAAGAAATATTCTTCCCGGTTGGTATGTTATGA

Upstream 100 bases:

>100_bases
CGAGGACGAAAGGATCGTAGCGCGTGATATTCAAGAGATTTTACAGAAATTCGGCTACACTTCGATAGGTATTGCGACTA
ACGGATAAAAGGCGATCCAG

Downstream 100 bases:

>100_bases
AAGATCGCCGCGCTTCGTCCAACGCTGGTAAGAGATGTTGTTGGCCTAACAGGGCGGAGGGTGCAGATGCAAAATAGCAA
CGAAGACAAATTGCTTGAAA

Product: adenylate cyclase-like protein

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 2; Adenylyl cyclase 2; AC2 [H]

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MAREIRPDLVLIDIVLGTGFIDGVETVVKLKEILDVPVIYVTADSDEATLKRARVTEPFGYILKPINVRELEITVEMCLY
RHKMEKRFREDASWLTTTLSSIGDGVIATDSISRVKFLNPVAEALLGMNEKAVRGRIVDDVMHLRDMKGAIIQNLVSYAT
INQSPAVFEHVILSDSNGRSTPVICTVAPIHDTNGTSHGCVFTLRDISELYAKSQELSKRMEDVEQAKRLLEKYFPENLV
DYLVDEKRQMELEGKNVQATMLFCDVRNSTGIAERLNPDEFAAFLSELFTGLMDITYANGGSVNKLLGDGLLITFGCPFP
EEEDTINCVRLALQIREYLRAFNDNRNPKILTPVAMGIGISTGNVFAGNVGSSRHMEYTVLGDAVNTASRLEALTKTTGH
DILLDSFTSDFIRHEINVEPIGTFLLRGKKEPQEIFFPVGML

Sequences:

>Translated_442_residues
MAREIRPDLVLIDIVLGTGFIDGVETVVKLKEILDVPVIYVTADSDEATLKRARVTEPFGYILKPINVRELEITVEMCLY
RHKMEKRFREDASWLTTTLSSIGDGVIATDSISRVKFLNPVAEALLGMNEKAVRGRIVDDVMHLRDMKGAIIQNLVSYAT
INQSPAVFEHVILSDSNGRSTPVICTVAPIHDTNGTSHGCVFTLRDISELYAKSQELSKRMEDVEQAKRLLEKYFPENLV
DYLVDEKRQMELEGKNVQATMLFCDVRNSTGIAERLNPDEFAAFLSELFTGLMDITYANGGSVNKLLGDGLLITFGCPFP
EEEDTINCVRLALQIREYLRAFNDNRNPKILTPVAMGIGISTGNVFAGNVGSSRHMEYTVLGDAVNTASRLEALTKTTGH
DILLDSFTSDFIRHEINVEPIGTFLLRGKKEPQEIFFPVGML
>Mature_441_residues
AREIRPDLVLIDIVLGTGFIDGVETVVKLKEILDVPVIYVTADSDEATLKRARVTEPFGYILKPINVRELEITVEMCLYR
HKMEKRFREDASWLTTTLSSIGDGVIATDSISRVKFLNPVAEALLGMNEKAVRGRIVDDVMHLRDMKGAIIQNLVSYATI
NQSPAVFEHVILSDSNGRSTPVICTVAPIHDTNGTSHGCVFTLRDISELYAKSQELSKRMEDVEQAKRLLEKYFPENLVD
YLVDEKRQMELEGKNVQATMLFCDVRNSTGIAERLNPDEFAAFLSELFTGLMDITYANGGSVNKLLGDGLLITFGCPFPE
EEDTINCVRLALQIREYLRAFNDNRNPKILTPVAMGIGISTGNVFAGNVGSSRHMEYTVLGDAVNTASRLEALTKTTGHD
ILLDSFTSDFIRHEINVEPIGTFLLRGKKEPQEIFFPVGML

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI17534657, Length=269, Percent_Identity=27.1375464684015, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17534649, Length=228, Percent_Identity=28.0701754385965, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193207841, Length=235, Percent_Identity=28.936170212766, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17534651, Length=229, Percent_Identity=28.3842794759825, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI212645052, Length=193, Percent_Identity=30.5699481865285, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17561802, Length=193, Percent_Identity=31.0880829015544, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00072 Response_reg [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 49258; Mature: 49127

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAREIRPDLVLIDIVLGTGFIDGVETVVKLKEILDVPVIYVTADSDEATLKRARVTEPFG
CCCCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCHH
YILKPINVRELEITVEMCLYRHKMEKRFREDASWLTTTLSSIGDGVIATDSISRVKFLNP
HHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHH
VAEALLGMNEKAVRGRIVDDVMHLRDMKGAIIQNLVSYATINQSPAVFEHVILSDSNGRS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEEECCCCCC
TPVICTVAPIHDTNGTSHGCVFTLRDISELYAKSQELSKRMEDVEQAKRLLEKYFPENLV
CCEEEEEEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
DYLVDEKRQMELEGKNVQATMLFCDVRNSTGIAERLNPDEFAAFLSELFTGLMDITYANG
HHHHCCCHHHEECCCCEEEEEEEEECCCCCCHHHCCCHHHHHHHHHHHHHHHHHEEECCC
GSVNKLLGDGLLITFGCPFPEEEDTINCVRLALQIREYLRAFNDNRNPKILTPVAMGIGI
CCHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHEEE
STGNVFAGNVGSSRHMEYTVLGDAVNTASRLEALTKTTGHDILLDSFTSDFIRHEINVEP
CCCCEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCH
IGTFLLRGKKEPQEIFFPVGML
HHHHHHCCCCCCHHHCCCCCCC
>Mature Secondary Structure 
AREIRPDLVLIDIVLGTGFIDGVETVVKLKEILDVPVIYVTADSDEATLKRARVTEPFG
CCCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCHH
YILKPINVRELEITVEMCLYRHKMEKRFREDASWLTTTLSSIGDGVIATDSISRVKFLNP
HHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHH
VAEALLGMNEKAVRGRIVDDVMHLRDMKGAIIQNLVSYATINQSPAVFEHVILSDSNGRS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEEECCCCCC
TPVICTVAPIHDTNGTSHGCVFTLRDISELYAKSQELSKRMEDVEQAKRLLEKYFPENLV
CCEEEEEEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
DYLVDEKRQMELEGKNVQATMLFCDVRNSTGIAERLNPDEFAAFLSELFTGLMDITYANG
HHHHCCCHHHEECCCCEEEEEEEEECCCCCCHHHCCCHHHHHHHHHHHHHHHHHEEECCC
GSVNKLLGDGLLITFGCPFPEEEDTINCVRLALQIREYLRAFNDNRNPKILTPVAMGIGI
CCHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHEEE
STGNVFAGNVGSSRHMEYTVLGDAVNTASRLEALTKTTGHDILLDSFTSDFIRHEINVEP
CCCCEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCH
IGTFLLRGKKEPQEIFFPVGML
HHHHHHCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]