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The map label for this gene is yccK [H]

Identifier: 116327901

GI number: 116327901

Start: 1400590

End: 1401534

Strand: Direct

Name: yccK [H]

Synonym: LBL_1186

Alternate gene names: 116327901

Gene position: 1400590-1401534 (Clockwise)

Preceding gene: 116327900

Following gene: 116327902

Centisome position: 38.75

GC content: 37.67

Gene sequence:

>945_bases
TTGGGGATTGAAGAAGAAGATTATATCACTCTACCTAAAACCGATCTCAAAGTTTCTCGATTGAGCATAGGTACCTGGTT
ATTTGGAGGTCTTCGTTGGGGTTATGTAGACAATCGGGAAAGTGAAAAAACTTTTTTATCTGCTCTCGATCTTGGAATCA
ATTTTATCGATACGGCTGATGCCTATGGAAAGGGGCAGTCAGAGGAATTTGTCTCTCGATTGACAAAAGGTAGAAAAGAA
AATTTAGTAATTGGGACAAAGGCAGGGGTTGTTTGGAATACGGATGGCACAAGAAGGATTGATTTATCTAAAAGACATCT
TACCGAAGCGGCGGAAAGAAGTTTGCAAAGACTTAAATTAGACAAGATTGATTTATATTATTTGCATGAACCAGATGTAA
ATACAGATATAGAAGAAACAATAGAAGCGTTGCAACTATTAAAAGCTCAAGGTAAAATTCGTTATATTGGCCTTTCTAAT
TTTCCGAAAGAAACCGTTGCTCAGTTTAATTCGATGATGCACGTTTCCTGCTTGCAGGACGAGCTTAGTTTAATTCGCAG
AGAAGCCGAATTAACGAATCTGAAATTCGCAAAAGAAAATAATTTAGGATTTTTGGCTTATAGCCCTTTGTCAAAAGGAC
TTCTTACGGGAAAGTTTAAATTCGATAGTCAATTCCCTTCTGACGACAATCGCTCGGGGAATGAAGATTTTTCAGGTGAA
AGATTGAAGAAGAATATTGAGAAAGTAGCTATACTTTCTCAATTTGCAAAAAGACTAGGATATACGGCATCGGCCGTTTC
TATTGCTTGGGTTTTAGGTATAGATTCAGTAACGTCTGTTGTCTTAGGTGCCAGAACGCAGGAACAATTGGAAGAGCAGA
TGAAGAGTCTCGAAGTTGTTTTTGAGTTAGATGCATATCAGCAAGTAGAGCGGATTTTTAGTTAA

Upstream 100 bases:

>100_bases
GGTAATCCGTCCGATCTCGTTGGTGGTGTTTTCTTTTTAACTTCTTCTCTATCGGAATATGTAACGGGTCAGAATCTTCT
CATTGATGGAGGGTTTACGA

Downstream 100 bases:

>100_bases
GGGAAATTTTATATGAGTCAAGAAATTACTTTAGGAAATATTAAAATAGGTGGCAATAACCCTGTTTTTATTATAGCAGA
AGCTGGTTTGAATCATGGTG

Product: Aryl-alcohol dehydrogenase-related oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MGIEEEDYITLPKTDLKVSRLSIGTWLFGGLRWGYVDNRESEKTFLSALDLGINFIDTADAYGKGQSEEFVSRLTKGRKE
NLVIGTKAGVVWNTDGTRRIDLSKRHLTEAAERSLQRLKLDKIDLYYLHEPDVNTDIEETIEALQLLKAQGKIRYIGLSN
FPKETVAQFNSMMHVSCLQDELSLIRREAELTNLKFAKENNLGFLAYSPLSKGLLTGKFKFDSQFPSDDNRSGNEDFSGE
RLKKNIEKVAILSQFAKRLGYTASAVSIAWVLGIDSVTSVVLGARTQEQLEEQMKSLEVVFELDAYQQVERIFS

Sequences:

>Translated_314_residues
MGIEEEDYITLPKTDLKVSRLSIGTWLFGGLRWGYVDNRESEKTFLSALDLGINFIDTADAYGKGQSEEFVSRLTKGRKE
NLVIGTKAGVVWNTDGTRRIDLSKRHLTEAAERSLQRLKLDKIDLYYLHEPDVNTDIEETIEALQLLKAQGKIRYIGLSN
FPKETVAQFNSMMHVSCLQDELSLIRREAELTNLKFAKENNLGFLAYSPLSKGLLTGKFKFDSQFPSDDNRSGNEDFSGE
RLKKNIEKVAILSQFAKRLGYTASAVSIAWVLGIDSVTSVVLGARTQEQLEEQMKSLEVVFELDAYQQVERIFS
>Mature_313_residues
GIEEEDYITLPKTDLKVSRLSIGTWLFGGLRWGYVDNRESEKTFLSALDLGINFIDTADAYGKGQSEEFVSRLTKGRKEN
LVIGTKAGVVWNTDGTRRIDLSKRHLTEAAERSLQRLKLDKIDLYYLHEPDVNTDIEETIEALQLLKAQGKIRYIGLSNF
PKETVAQFNSMMHVSCLQDELSLIRREAELTNLKFAKENNLGFLAYSPLSKGLLTGKFKFDSQFPSDDNRSGNEDFSGER
LKKNIEKVAILSQFAKRLGYTASAVSIAWVLGIDSVTSVVLGARTQEQLEEQMKSLEVVFELDAYQQVERIFS

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436962, Length=316, Percent_Identity=31.0126582278481, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI27436964, Length=316, Percent_Identity=31.0126582278481, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI27436966, Length=313, Percent_Identity=30.9904153354633, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI4504825, Length=315, Percent_Identity=31.1111111111111, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI27436969, Length=315, Percent_Identity=31.1111111111111, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI27436971, Length=314, Percent_Identity=30.5732484076433, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI41327764, Length=274, Percent_Identity=31.021897810219, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI223718702, Length=315, Percent_Identity=29.2063492063492, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI41152114, Length=280, Percent_Identity=30, Blast_Score=89, Evalue=4e-18,
Organism=Escherichia coli, GI1788070, Length=306, Percent_Identity=33.3333333333333, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI87081735, Length=319, Percent_Identity=30.7210031347962, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1789375, Length=304, Percent_Identity=32.2368421052632, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1789199, Length=349, Percent_Identity=30.3724928366762, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788081, Length=305, Percent_Identity=26.8852459016393, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787674, Length=289, Percent_Identity=25.2595155709343, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI48994888, Length=169, Percent_Identity=31.9526627218935, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI212645785, Length=293, Percent_Identity=26.962457337884, Blast_Score=85, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6325169, Length=330, Percent_Identity=27.5757575757576, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323998, Length=322, Percent_Identity=25.1552795031056, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319958, Length=294, Percent_Identity=25.1700680272109, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319951, Length=321, Percent_Identity=25.2336448598131, Blast_Score=76, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24640980, Length=336, Percent_Identity=26.7857142857143, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI45549126, Length=336, Percent_Identity=26.7857142857143, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24646155, Length=315, Percent_Identity=30.1587301587302, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24646159, Length=223, Percent_Identity=28.2511210762332, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24644950, Length=309, Percent_Identity=25.5663430420712, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35512; Mature: 35381

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00062 ALDOKETO_REDUCTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIEEEDYITLPKTDLKVSRLSIGTWLFGGLRWGYVDNRESEKTFLSALDLGINFIDTAD
CCCCCCCEEECCCCCCEEHHEEHHHHHHCCEEECCCCCCCHHHHHHHHHHHCCCEEECCH
AYGKGQSEEFVSRLTKGRKENLVIGTKAGVVWNTDGTRRIDLSKRHLTEAAERSLQRLKL
HCCCCCHHHHHHHHHCCCCCCEEEEECCCEEECCCCCEEECCHHHHHHHHHHHHHHHHCC
DKIDLYYLHEPDVNTDIEETIEALQLLKAQGKIRYIGLSNFPKETVAQFNSMMHVSCLQD
CCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
ELSLIRREAELTNLKFAKENNLGFLAYSPLSKGLLTGKFKFDSQFPSDDNRSGNEDFSGE
HHHHHHHHHHHHHCEEEECCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHH
RLKKNIEKVAILSQFAKRLGYTASAVSIAWVLGIDSVTSVVLGARTQEQLEEQMKSLEVV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FELDAYQQVERIFS
HHHHHHHHHHHHCC
>Mature Secondary Structure 
GIEEEDYITLPKTDLKVSRLSIGTWLFGGLRWGYVDNRESEKTFLSALDLGINFIDTAD
CCCCCCEEECCCCCCEEHHEEHHHHHHCCEEECCCCCCCHHHHHHHHHHHCCCEEECCH
AYGKGQSEEFVSRLTKGRKENLVIGTKAGVVWNTDGTRRIDLSKRHLTEAAERSLQRLKL
HCCCCCHHHHHHHHHCCCCCCEEEEECCCEEECCCCCEEECCHHHHHHHHHHHHHHHHCC
DKIDLYYLHEPDVNTDIEETIEALQLLKAQGKIRYIGLSNFPKETVAQFNSMMHVSCLQD
CCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
ELSLIRREAELTNLKFAKENNLGFLAYSPLSKGLLTGKFKFDSQFPSDDNRSGNEDFSGE
HHHHHHHHHHHHHCEEEECCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHH
RLKKNIEKVAILSQFAKRLGYTASAVSIAWVLGIDSVTSVVLGARTQEQLEEQMKSLEVV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FELDAYQQVERIFS
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]