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The map label for this gene is 116327902

Identifier: 116327902

GI number: 116327902

Start: 1401547

End: 1402395

Strand: Direct

Name: 116327902

Synonym: LBL_1187

Alternate gene names: NA

Gene position: 1401547-1402395 (Clockwise)

Preceding gene: 116327901

Following gene: 116327903

Centisome position: 38.78

GC content: 35.1

Gene sequence:

>849_bases
ATGAGTCAAGAAATTACTTTAGGAAATATTAAAATAGGTGGCAATAACCCTGTTTTTATTATAGCAGAAGCTGGTTTGAA
TCATGGTGGAGATTTAAACCTTGCCTTACGAATGATTGATGAGGCAGCAGACGCAAAGGCAAATGCCATAAAATTTCAAG
CTTACAATAGCGAGGAACGATTTGGTGAAAATAAAGAAGCTGTGAATTTGGTCAAACCGGCAGAATTTGGAAAAAAAGAA
TTTTTATTATTAAAAGAAAGATCTCAAAAGAAAAATATACTTTTTTTTGCTACGCCATTTGACGTTCCAAATTTAAATAT
GCTCAAAGAAATCGGGGTTGAAATTTTAAAGATTGCTTCTTGCGATATTTGTAATATAACATTATTAGAAGCTGCTGCCG
ATTCGGGTTTGATTGTGATTCTTTCTCGTGGAACTGCGTCTGCTTCTGAAATAGAGACAGCAGTATCTATTTTTAAGAAA
AAGAAATCCCCTTTTATTCTGTTGCATTGCGTGTCTTCTTATCCAATGAATGAAATAGATGCGAATTTATCCGCTATTCA
GACTTTAAAATCTAAATATGAATTTCCGATTGGATACTCGGATCATAGTAAGGGAATTGAAATACCTTTGCTTGCAGTTG
CAAGCGGTGCAGAGATTATCGAAAAACATTATACTGTGGATCGAACTCTACAGGGAATTGATTGGGAAATCTCTGCAGAG
CCTAAGGAACTTGCTAAATTAGTGACGGAGACAGAGCGCATTCGTAAAATTCTTGGGCATGGAAAGTTAGAACCCCAAGC
TTCTGAACAAGAAGAAATAGAATATAGAAATAGTCTTAGAAGAAAGTAA

Upstream 100 bases:

>100_bases
GCAGGAACAATTGGAAGAGCAGATGAAGAGTCTCGAAGTTGTTTTTGAGTTAGATGCATATCAGCAAGTAGAGCGGATTT
TTAGTTAAGGGAAATTTTAT

Downstream 100 bases:

>100_bases
AAATGGTAATTGTATTTCGGGCGGATGGAGGGACTCGGCCAGATATAGCAATGGGGCATATTTACAGATCTTGCTTGATA
GCTGACCAGTTAAAAAATAG

Product: N-acetylneuraminic acid (sialic acid) synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSQEITLGNIKIGGNNPVFIIAEAGLNHGGDLNLALRMIDEAADAKANAIKFQAYNSEERFGENKEAVNLVKPAEFGKKE
FLLLKERSQKKNILFFATPFDVPNLNMLKEIGVEILKIASCDICNITLLEAAADSGLIVILSRGTASASEIETAVSIFKK
KKSPFILLHCVSSYPMNEIDANLSAIQTLKSKYEFPIGYSDHSKGIEIPLLAVASGAEIIEKHYTVDRTLQGIDWEISAE
PKELAKLVTETERIRKILGHGKLEPQASEQEEIEYRNSLRRK

Sequences:

>Translated_282_residues
MSQEITLGNIKIGGNNPVFIIAEAGLNHGGDLNLALRMIDEAADAKANAIKFQAYNSEERFGENKEAVNLVKPAEFGKKE
FLLLKERSQKKNILFFATPFDVPNLNMLKEIGVEILKIASCDICNITLLEAAADSGLIVILSRGTASASEIETAVSIFKK
KKSPFILLHCVSSYPMNEIDANLSAIQTLKSKYEFPIGYSDHSKGIEIPLLAVASGAEIIEKHYTVDRTLQGIDWEISAE
PKELAKLVTETERIRKILGHGKLEPQASEQEEIEYRNSLRRK
>Mature_281_residues
SQEITLGNIKIGGNNPVFIIAEAGLNHGGDLNLALRMIDEAADAKANAIKFQAYNSEERFGENKEAVNLVKPAEFGKKEF
LLLKERSQKKNILFFATPFDVPNLNMLKEIGVEILKIASCDICNITLLEAAADSGLIVILSRGTASASEIETAVSIFKKK
KSPFILLHCVSSYPMNEIDANLSAIQTLKSKYEFPIGYSDHSKGIEIPLLAVASGAEIIEKHYTVDRTLQGIDWEISAEP
KELAKLVTETERIRKILGHGKLEPQASEQEEIEYRNSLRRK

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=266, Percent_Identity=35.3383458646617, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI21357081, Length=255, Percent_Identity=34.1176470588235, Blast_Score=139, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 31215; Mature: 31084

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQEITLGNIKIGGNNPVFIIAEAGLNHGGDLNLALRMIDEAADAKANAIKFQAYNSEER
CCCCEEEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCHHH
FGENKEAVNLVKPAEFGKKEFLLLKERSQKKNILFFATPFDVPNLNMLKEIGVEILKIAS
CCCCCHHEEEECCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCC
CDICNITLLEAAADSGLIVILSRGTASASEIETAVSIFKKKKSPFILLHCVSSYPMNEID
CCCCEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHH
ANLSAIQTLKSKYEFPIGYSDHSKGIEIPLLAVASGAEIIEKHYTVDRTLQGIDWEISAE
CHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEECCC
PKELAKLVTETERIRKILGHGKLEPQASEQEEIEYRNSLRRK
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SQEITLGNIKIGGNNPVFIIAEAGLNHGGDLNLALRMIDEAADAKANAIKFQAYNSEER
CCCEEEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCHHH
FGENKEAVNLVKPAEFGKKEFLLLKERSQKKNILFFATPFDVPNLNMLKEIGVEILKIAS
CCCCCHHEEEECCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCC
CDICNITLLEAAADSGLIVILSRGTASASEIETAVSIFKKKKSPFILLHCVSSYPMNEID
CCCCEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHH
ANLSAIQTLKSKYEFPIGYSDHSKGIEIPLLAVASGAEIIEKHYTVDRTLQGIDWEISAE
CHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEECCC
PKELAKLVTETERIRKILGHGKLEPQASEQEEIEYRNSLRRK
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]