BacMap

Definition	Leptospira borgpetersenii serovar Hardjo-bovis L550 chromosome 1, complete sequence.
Accession	NC_008508
Length	3,614,446

Click here to switch to the map view.

The map label for this gene is fabG [H]

Identifier: 116327900

GI number: 116327900

Start: 1399833

End: 1400600

Strand: Direct

Name: fabG [H]

Synonym: LBL_1185

Alternate gene names: 116327900

Gene position: 1399833-1400600 (Clockwise)

Preceding gene: 116327899

Following gene: 116327901

Centisome position: 38.73

GC content: 37.11

Gene sequence:

>768_bases
ATGATTTTGAAAAATTTCTCTGATGAATTTCAAGATAAACTTGTTTTAATTACGGGTGGAAGTGGGCAGATAGGGTCAGA
ACTGGTAGAGTCATATTTGAGCGTATCTGCTCGTGTTATCTGTTTAGATCCAGAACAGCCTTCAGTAGATTACAAATCAA
ATCGGTTCGAATGGATTCAAGCAGACATAACGAATCGTAAAGAAATAAAAGAGATTTTTTTATCCTTAGAGAATCAAAAT
AAAATCCCGGACATCTTAATCAATTGTGCGGGGATCTCTGTATTTACACCTTTTGAGGATAGAACGGACGAAGAATTTAA
CGAAGTCGTGCATGTAAATTTGAACGGGACTTTTTTACTCTCTCAATATACTTTCCGTCTTTGGAAAGAAAAAGGGAAGA
AAGGAATCATTTTGAACTTCGGATCTATCTATGGTGTTTCGATTGCAGATATGAGAATCTATGGAGACTCCGGAAGAAAT
AGTCCTGAAGTGTATGCAATGACAAAAGCTGGGATCATACATTTTACGAAATATCTGGCCAGATATGCTGCTCCTTACGG
AATCAGAGTCAATTGCATTAGCCCTGGAGGAATTTTTGCAAACCAGAGTTCTGATTTTATTCAAAATTATATATATAAAA
CACCTCTTGGTAGAATGGGTAATCCGTCCGATCTCGTTGGTGGTGTTTTCTTTTTAACTTCTTCTCTATCGGAATATGTA
ACGGGTCAGAATCTTCTCATTGATGGAGGGTTTACGATTGGGGATTGA

Upstream 100 bases:

>100_bases
TGTTTAAGACTTTAAATGATTATCATTTAATGCCCTGGGACAAAAAAGATAGAATGTATGCAGAAGAACATTTCAATACA
TTAGAAGGAATTACAAAATC

Downstream 100 bases:

>100_bases
AGAAGAAGATTATATCACTCTACCTAAAACCGATCTCAAAGTTTCTCGATTGAGCATAGGTACCTGGTTATTTGGAGGTC
TTCGTTGGGGTTATGTAGAC

Product: Short chain dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MILKNFSDEFQDKLVLITGGSGQIGSELVESYLSVSARVICLDPEQPSVDYKSNRFEWIQADITNRKEIKEIFLSLENQN
KIPDILINCAGISVFTPFEDRTDEEFNEVVHVNLNGTFLLSQYTFRLWKEKGKKGIILNFGSIYGVSIADMRIYGDSGRN
SPEVYAMTKAGIIHFTKYLARYAAPYGIRVNCISPGGIFANQSSDFIQNYIYKTPLGRMGNPSDLVGGVFFLTSSLSEYV
TGQNLLIDGGFTIGD

Sequences:

>Translated_255_residues
MILKNFSDEFQDKLVLITGGSGQIGSELVESYLSVSARVICLDPEQPSVDYKSNRFEWIQADITNRKEIKEIFLSLENQN
KIPDILINCAGISVFTPFEDRTDEEFNEVVHVNLNGTFLLSQYTFRLWKEKGKKGIILNFGSIYGVSIADMRIYGDSGRN
SPEVYAMTKAGIIHFTKYLARYAAPYGIRVNCISPGGIFANQSSDFIQNYIYKTPLGRMGNPSDLVGGVFFLTSSLSEYV
TGQNLLIDGGFTIGD
>Mature_255_residues
MILKNFSDEFQDKLVLITGGSGQIGSELVESYLSVSARVICLDPEQPSVDYKSNRFEWIQADITNRKEIKEIFLSLENQN
KIPDILINCAGISVFTPFEDRTDEEFNEVVHVNLNGTFLLSQYTFRLWKEKGKKGIILNFGSIYGVSIADMRIYGDSGRN
SPEVYAMTKAGIIHFTKYLARYAAPYGIRVNCISPGGIFANQSSDFIQNYIYKTPLGRMGNPSDLVGGVFFLTSSLSEYV
TGQNLLIDGGFTIGD

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=270, Percent_Identity=25.5555555555556, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI19923817, Length=265, Percent_Identity=26.0377358490566, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=28.1124497991968, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI10190704, Length=264, Percent_Identity=25.3787878787879, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI59889578, Length=243, Percent_Identity=26.3374485596708, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=25.3061224489796, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4758504, Length=198, Percent_Identity=26.2626262626263, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=24.4186046511628, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI4503301, Length=204, Percent_Identity=26.4705882352941, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI66933014, Length=202, Percent_Identity=25.7425742574257, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=30.8, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=28.6274509803922, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789208, Length=262, Percent_Identity=25.5725190839695, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=27.7992277992278, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788459, Length=209, Percent_Identity=27.7511961722488, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1789378, Length=266, Percent_Identity=27.8195488721804, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI87082160, Length=266, Percent_Identity=25.187969924812, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1786812, Length=260, Percent_Identity=23.0769230769231, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787905, Length=251, Percent_Identity=26.6932270916335, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI2367175, Length=265, Percent_Identity=26.0377358490566, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=25.5060728744939, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=254, Percent_Identity=28.740157480315, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI25147288, Length=252, Percent_Identity=28.968253968254, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17536651, Length=260, Percent_Identity=26.5384615384615, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=257, Percent_Identity=25.6809338521401, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=177, Percent_Identity=32.2033898305085, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=177, Percent_Identity=31.0734463276836, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=265, Percent_Identity=26.4150943396226, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=277, Percent_Identity=25.9927797833935, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=204, Percent_Identity=25, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=260, Percent_Identity=24.2307692307692, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=260, Percent_Identity=24.6153846153846, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=277, Percent_Identity=26.3537906137184, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=275, Percent_Identity=25.8181818181818, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=272, Percent_Identity=25.7352941176471, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=276, Percent_Identity=26.0869565217391, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=26.3940520446097, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=273, Percent_Identity=25.2747252747253, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=278, Percent_Identity=25.1798561151079, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6324126, Length=261, Percent_Identity=25.6704980842912, Blast_Score=73, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6322861, Length=239, Percent_Identity=27.6150627615063, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=30.8, Blast_Score=110, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24643142, Length=257, Percent_Identity=27.6264591439689, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=29.8449612403101, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28571526, Length=263, Percent_Identity=25.8555133079848, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24644339, Length=271, Percent_Identity=27.3062730627306, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21357041, Length=262, Percent_Identity=26.7175572519084, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24644337, Length=262, Percent_Identity=28.6259541984733, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355319, Length=256, Percent_Identity=24.21875, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24665243, Length=214, Percent_Identity=27.1028037383178, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI221331218, Length=214, Percent_Identity=27.1028037383178, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24665247, Length=215, Percent_Identity=26.5116279069767, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221331216, Length=215, Percent_Identity=26.5116279069767, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 28456; Mature: 28456

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILKNFSDEFQDKLVLITGGSGQIGSELVESYLSVSARVICLDPEQPSVDYKSNRFEWIQ
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEE
ADITNRKEIKEIFLSLENQNKIPDILINCAGISVFTPFEDRTDEEFNEVVHVNLNGTFLL
ECCCCHHHHHHHHHHHCCCCCCCEEEEEECCEEEECCCCCCCCCCCCCEEEEECCCEEEE
SQYTFRLWKEKGKKGIILNFGSIYGVSIADMRIYGDSGRNSPEVYAMTKAGIIHFTKYLA
HHHHHHHHHHCCCCEEEEEECCEEEEEEEEEEEECCCCCCCCEEEEEEHHHHHHHHHHHH
RYAAPYGIRVNCISPGGIFANQSSDFIQNYIYKTPLGRMGNPSDLVGGVFFLTSSLSEYV
HHCCCCCEEEEEECCCCEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
TGQNLLIDGGFTIGD
CCCEEEEECCEEECC
>Mature Secondary Structure
MILKNFSDEFQDKLVLITGGSGQIGSELVESYLSVSARVICLDPEQPSVDYKSNRFEWIQ
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEE
ADITNRKEIKEIFLSLENQNKIPDILINCAGISVFTPFEDRTDEEFNEVVHVNLNGTFLL
ECCCCHHHHHHHHHHHCCCCCCCEEEEEECCEEEECCCCCCCCCCCCCEEEEECCCEEEE
SQYTFRLWKEKGKKGIILNFGSIYGVSIADMRIYGDSGRNSPEVYAMTKAGIIHFTKYLA
HHHHHHHHHHCCCCEEEEEECCEEEEEEEEEEEECCCCCCCCEEEEEEHHHHHHHHHHHH
RYAAPYGIRVNCISPGGIFANQSSDFIQNYIYKTPLGRMGNPSDLVGGVFFLTSSLSEYV
HHCCCCCEEEEEECCCCEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
TGQNLLIDGGFTIGD
CCCEEEEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1556094; 8905232; 9278503; 1314802 [H]