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The map label for this gene is ispA-1 [H]

Identifier: 116327487

GI number: 116327487

Start: 806192

End: 807133

Strand: Direct

Name: ispA-1 [H]

Synonym: LBL_0711

Alternate gene names: 116327487

Gene position: 806192-807133 (Clockwise)

Preceding gene: 116327485

Following gene: 116327488

Centisome position: 22.3

GC content: 41.4

Gene sequence:

>942_bases
GTGAGTCTATCTTCTTTTTCCGCTATATTCCATTCTTATAGAGTTACGTTTGAGAATTTTTTAAACTCTCAAACCCTTTC
CATACTTTCCGAACAATCCGCCCCCGAACTTTTTGAAGCCATGAAATACAGTCTTGTTGCCGGAGGTAAACGACTCAGAC
CGGTTTTGGTATTGGCGGCTTTCGGCGGATCTCAAAACGAAACTCGAAACACTCTTCTTCTCGGGTCGTCTTTGGAATGT
ATACATACCTATTCTTTGATTCACGACGATCTTCCAAGTATGGACAACGACGATTTTAGAAGGGGTTTACCGACTCTTCA
TAAGAGGTTTTCCGAGGCCACGGCGATTTTGACGGGCGACGCGTTAAATTCTTTCGCGTTTTATTTTATCTCTTTGATTC
AAGGGGATAATGAGGATTATTTTTTGCATCGGGATTTATTAGAAATTTTGCATACAGGTTGTGGTGCGCCCGGAATGGTC
TCCGGACAAATATATGATTTACAGATGGAAAGGGAAAATACGAAGAACCGAAATTCTAAGAGCGAACAAGAAAAGGTCGC
GATGGTCCAATTGACTCATCGTTTAAAAACGGGAGCTCTCATTAAGGCTGCCTTACTTTTGGGAAATCGTCTTCGTAAGG
ATTGGAAAAAAAGAGAGGGGCCTTTATCCAAATACGGAGAAGATCTAGGTTTGCTTTTCCAAATTACCGACGACATTTTG
GATGTGGAGGGAACTCAGGAATCCTTGGGTAAAACTCCGGGTAAGGATCAAAGAACGGGTAAGATCACATATCCTGCGTT
GTTAGGAATGGAACGTTGTAAAAAAATGGTCCAAGAACTTCAAAAAAATCTAATTTCCATCTCTTCTAGTTTTGTTTCCA
CGGACGAAGAGGGAACATTCTTTCAGGGGCTTCCGATTTACATTGGCCAAAGAAAAAATTAG

Upstream 100 bases:

>100_bases
TTTTTCAACAACTCTATTTTAGTTTGTTGCGAGATAAGTTCTTATATGACTATCGGACTTTGCTTTACAATTCGAAGTTT
TCTTTCAATTTGGAGGCAGA

Downstream 100 bases:

>100_bases
ACTCGATGTTCTTCTCCTAGAACGGGGACTTGCGGATTCTCCGGAAAAATCGAGAAGTTTGATTCTTTCCGGTTCCGTCT
TGGTAAACGAACAAAAAATA

Product: geranyltranstransferase

Products: NA

Alternate protein names: FPP synthase; (2E,6E)-farnesyl diphosphate synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSLSSFSAIFHSYRVTFENFLNSQTLSILSEQSAPELFEAMKYSLVAGGKRLRPVLVLAAFGGSQNETRNTLLLGSSLEC
IHTYSLIHDDLPSMDNDDFRRGLPTLHKRFSEATAILTGDALNSFAFYFISLIQGDNEDYFLHRDLLEILHTGCGAPGMV
SGQIYDLQMERENTKNRNSKSEQEKVAMVQLTHRLKTGALIKAALLLGNRLRKDWKKREGPLSKYGEDLGLLFQITDDIL
DVEGTQESLGKTPGKDQRTGKITYPALLGMERCKKMVQELQKNLISISSSFVSTDEEGTFFQGLPIYIGQRKN

Sequences:

>Translated_313_residues
MSLSSFSAIFHSYRVTFENFLNSQTLSILSEQSAPELFEAMKYSLVAGGKRLRPVLVLAAFGGSQNETRNTLLLGSSLEC
IHTYSLIHDDLPSMDNDDFRRGLPTLHKRFSEATAILTGDALNSFAFYFISLIQGDNEDYFLHRDLLEILHTGCGAPGMV
SGQIYDLQMERENTKNRNSKSEQEKVAMVQLTHRLKTGALIKAALLLGNRLRKDWKKREGPLSKYGEDLGLLFQITDDIL
DVEGTQESLGKTPGKDQRTGKITYPALLGMERCKKMVQELQKNLISISSSFVSTDEEGTFFQGLPIYIGQRKN
>Mature_312_residues
SLSSFSAIFHSYRVTFENFLNSQTLSILSEQSAPELFEAMKYSLVAGGKRLRPVLVLAAFGGSQNETRNTLLLGSSLECI
HTYSLIHDDLPSMDNDDFRRGLPTLHKRFSEATAILTGDALNSFAFYFISLIQGDNEDYFLHRDLLEILHTGCGAPGMVS
GQIYDLQMERENTKNRNSKSEQEKVAMVQLTHRLKTGALIKAALLLGNRLRKDWKKREGPLSKYGEDLGLLFQITDDILD
VEGTQESLGKTPGKDQRTGKITYPALLGMERCKKMVQELQKNLISISSSFVSTDEEGTFFQGLPIYIGQRKN

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786623, Length=296, Percent_Identity=40.8783783783784, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1789578, Length=237, Percent_Identity=29.957805907173, Blast_Score=86, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24651612, Length=248, Percent_Identity=27.4193548387097, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.10 [H]

Molecular weight: Translated: 35088; Mature: 34957

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSSFSAIFHSYRVTFENFLNSQTLSILSEQSAPELFEAMKYSLVAGGKRLRPVLVLAA
CCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEE
FGGSQNETRNTLLLGSSLECIHTYSLIHDDLPSMDNDDFRRGLPTLHKRFSEATAILTGD
CCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHEEECH
ALNSFAFYFISLIQGDNEDYFLHRDLLEILHTGCGAPGMVSGQIYDLQMERENTKNRNSK
HHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCCCCCCEEEEEEECHHCCCCCCCC
SEQEKVAMVQLTHRLKTGALIKAALLLGNRLRKDWKKREGPLSKYGEDLGLLFQITDDIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHEEEHHHHH
DVEGTQESLGKTPGKDQRTGKITYPALLGMERCKKMVQELQKNLISISSSFVSTDEEGTF
CCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
FQGLPIYIGQRKN
ECCCCEEECCCCC
>Mature Secondary Structure 
SLSSFSAIFHSYRVTFENFLNSQTLSILSEQSAPELFEAMKYSLVAGGKRLRPVLVLAA
CCHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEE
FGGSQNETRNTLLLGSSLECIHTYSLIHDDLPSMDNDDFRRGLPTLHKRFSEATAILTGD
CCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHEEECH
ALNSFAFYFISLIQGDNEDYFLHRDLLEILHTGCGAPGMVSGQIYDLQMERENTKNRNSK
HHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCCCCCCEEEEEEECHHCCCCCCCC
SEQEKVAMVQLTHRLKTGALIKAALLLGNRLRKDWKKREGPLSKYGEDLGLLFQITDDIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHEEEHHHHH
DVEGTQESLGKTPGKDQRTGKITYPALLGMERCKKMVQELQKNLISISSSFVSTDEEGTF
CCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
FQGLPIYIGQRKN
ECCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9515931 [H]