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The map label for this gene is caiD-1 [H]

Identifier: 116327427

GI number: 116327427

Start: 710001

End: 710747

Strand: Direct

Name: caiD-1 [H]

Synonym: LBL_0637

Alternate gene names: 116327427

Gene position: 710001-710747 (Clockwise)

Preceding gene: 116327426

Following gene: 116327431

Centisome position: 19.64

GC content: 41.63

Gene sequence:

>747_bases
ATGAAGTATCAGTTTTTGCTTACAGAACAAAGGGATAAGGTTCTTATCATCACTCTCAATCGACCTGAAAAATCCAATGC
TTTGAACGTACAAATCAGGGACGAACTCGAGGACGTATTCAATACAAACGCAAAGAACGATACGGTAAAGGCGATTCTTC
TCAATTCTTCGGGTAAAAACTTTTCGAGCGGCTACGATCTAGAAGAAGTCGTTCAAACGAAACTGGAATCTTTTCGTCAT
AGGATATTAGAATATCATTATTCGATTTATAGTTTCCCGAAACCGGTAATTACGATTTTGAGAGGTTTTGCGTCCGCCGG
AGGATTTGACCTGGCTCTTTGCGGAGATTACATCATTTCGGAGAAAAAGGCGATCCTTTATAGACCCGAGATCCGATTTG
GAGGTCCACCTTTGGTAACCACTCTCGCGAGAAAGATCGGACCTTCGAAAGCGCTGAGTTTGACTTTGAAGGGCGATCCG
ATTCGATCTTCTCAGGCATTGAGTTTAGGAGTTATCGACGAGGTCTATGAAGGAGAGGACGTTGTACAACACGCGTTTCA
AATCGCTTCCAAACTTTCTCAGTGGGATTTCAATACGTTGTCCGTCTTAAAGGGAATTGCAAATAACTATTTTATGGGAA
ACTTATATGAGAATCTGAAAAACGAATTTGAGGAGTTCGCTGTCGTATTAAAGGATCCGAAATTTTATCAAAGAGTTCGA
GACTACGCGGAGACGATTCGACAATGA

Upstream 100 bases:

>100_bases
TATTGTCTATTTATAGGGATTCCCGTTCGTTTTTCTTGCTTGAAAGTATGTCCGAGATTAAAACCGTGCGCATTTTTATT
TGAGTTGAAAAGGATCAAAC

Downstream 100 bases:

>100_bases
CGTTGGCGGCTACTTCTATTTCTTTAAATTTTTGGAAGGATTTAGGGCTTGTCCCAAAACCATTCGATCTTATCGGAATC
CTCGCGGATCGCTGCAATTG

Product: enoyl-CoA hydratase/carnithine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MKYQFLLTEQRDKVLIITLNRPEKSNALNVQIRDELEDVFNTNAKNDTVKAILLNSSGKNFSSGYDLEEVVQTKLESFRH
RILEYHYSIYSFPKPVITILRGFASAGGFDLALCGDYIISEKKAILYRPEIRFGGPPLVTTLARKIGPSKALSLTLKGDP
IRSSQALSLGVIDEVYEGEDVVQHAFQIASKLSQWDFNTLSVLKGIANNYFMGNLYENLKNEFEEFAVVLKDPKFYQRVR
DYAETIRQ

Sequences:

>Translated_248_residues
MKYQFLLTEQRDKVLIITLNRPEKSNALNVQIRDELEDVFNTNAKNDTVKAILLNSSGKNFSSGYDLEEVVQTKLESFRH
RILEYHYSIYSFPKPVITILRGFASAGGFDLALCGDYIISEKKAILYRPEIRFGGPPLVTTLARKIGPSKALSLTLKGDP
IRSSQALSLGVIDEVYEGEDVVQHAFQIASKLSQWDFNTLSVLKGIANNYFMGNLYENLKNEFEEFAVVLKDPKFYQRVR
DYAETIRQ
>Mature_248_residues
MKYQFLLTEQRDKVLIITLNRPEKSNALNVQIRDELEDVFNTNAKNDTVKAILLNSSGKNFSSGYDLEEVVQTKLESFRH
RILEYHYSIYSFPKPVITILRGFASAGGFDLALCGDYIISEKKAILYRPEIRFGGPPLVTTLARKIGPSKALSLTLKGDP
IRSSQALSLGVIDEVYEGEDVVQHAFQIASKLSQWDFNTLSVLKGIANNYFMGNLYENLKNEFEEFAVVLKDPKFYQRVR
DYAETIRQ

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=231, Percent_Identity=30.3030303030303, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI31542718, Length=203, Percent_Identity=26.1083743842365, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI70995211, Length=194, Percent_Identity=26.8041237113402, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI45643119, Length=186, Percent_Identity=25.2688172043011, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI260275230, Length=186, Percent_Identity=25.2688172043011, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI260274832, Length=186, Percent_Identity=25.2688172043011, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI20127408, Length=183, Percent_Identity=27.8688524590164, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787659, Length=193, Percent_Identity=27.979274611399, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1788682, Length=202, Percent_Identity=28.2178217821782, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI221142681, Length=199, Percent_Identity=27.1356783919598, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87082183, Length=211, Percent_Identity=25.5924170616114, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787660, Length=216, Percent_Identity=28.7037037037037, Blast_Score=71, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17554946, Length=214, Percent_Identity=28.5046728971963, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17560910, Length=200, Percent_Identity=30.5, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI25145438, Length=223, Percent_Identity=28.2511210762332, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17540714, Length=193, Percent_Identity=28.4974093264249, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17534483, Length=197, Percent_Identity=27.9187817258883, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17549921, Length=213, Percent_Identity=27.2300469483568, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=189, Percent_Identity=27.5132275132275, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20129971, Length=249, Percent_Identity=28.5140562248996, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24653477, Length=249, Percent_Identity=28.5140562248996, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21357171, Length=198, Percent_Identity=28.7878787878788, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24650670, Length=202, Percent_Identity=26.2376237623762, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19920382, Length=186, Percent_Identity=30.6451612903226, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28247; Mature: 28247

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYQFLLTEQRDKVLIITLNRPEKSNALNVQIRDELEDVFNTNAKNDTVKAILLNSSGKN
CCEEEEEECCCCEEEEEEECCCCCCCEEEEEEHHHHHHHHCCCCCCCEEEEEEEECCCCC
FSSGYDLEEVVQTKLESFRHRILEYHYSIYSFPKPVITILRGFASAGGFDLALCGDYIIS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHC
EKKAILYRPEIRFGGPPLVTTLARKIGPSKALSLTLKGDPIRSSQALSLGVIDEVYEGED
CCCEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEHHHHHHHHCCHH
VVQHAFQIASKLSQWDFNTLSVLKGIANNYFMGNLYENLKNEFEEFAVVLKDPKFYQRVR
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHH
DYAETIRQ
HHHHHHCC
>Mature Secondary Structure
MKYQFLLTEQRDKVLIITLNRPEKSNALNVQIRDELEDVFNTNAKNDTVKAILLNSSGKN
CCEEEEEECCCCEEEEEEECCCCCCCEEEEEEHHHHHHHHCCCCCCCEEEEEEEECCCCC
FSSGYDLEEVVQTKLESFRHRILEYHYSIYSFPKPVITILRGFASAGGFDLALCGDYIIS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHC
EKKAILYRPEIRFGGPPLVTTLARKIGPSKALSLTLKGDPIRSSQALSLGVIDEVYEGED
CCCEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEHHHHHHHHCCHH
VVQHAFQIASKLSQWDFNTLSVLKGIANNYFMGNLYENLKNEFEEFAVVLKDPKFYQRVR
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHH
DYAETIRQ
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]