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The map label for this gene is yrbG [C]

Identifier: 114800182

GI number: 114800182

Start: 466173

End: 467162

Strand: Direct

Name: yrbG [C]

Synonym: HNE_0473

Alternate gene names: 114800182

Gene position: 466173-467162 (Clockwise)

Preceding gene: 114799653

Following gene: 114797330

Centisome position: 12.58

GC content: 62.22

Gene sequence:

>990_bases
GTGCCCGATCCCATCCTGCTCATTTCCCTTTTTGGCGGTCTGCTTCTCATGGCGCTCGCCGGAGACCTGCTTGTGCGGGG
CGCGCTTGGCTTAGGCCGGGCGATGGGTGTTTCGCCGCTCGTAGCGGGCATTTTCATCGTTGGATTCGGCACATCAGCGC
CGGAGATGTTCATCTCCGCGAATGCCGCGCTCAATGGCAATCCCGGTCTCGCCATCGGCAACATTGTCGGCTCCAATATT
GCCAATCTTCTGATGGTTGCAGCCATTCCTGCGCTGTTCTTTCCCTATCGCACCGGCGGTGCCGGGCAGGGGCGGGCGTT
GTTCATGCTGCTGCTTGCGACGGCCATCTGGATCGGGATGACGGCCATCATGCCGCTCGACCCCATCATGGGCATCTGTT
TCCTGCTGGTGCTGGTGGGGTATGCGGGCTTTTCCATCTTTGCGGCGCGTCATGACGAGATTGCCGGAAAGGGCGCCCAT
CAGGCCGATGCGGTGATGCTCAACCCTCCCGTCTGGCGGGCGATTTTCTATGTGCCGCTGGGCATTGCGGGCCTTCTCTA
TGCCTCACGCATGATCATCACGGGCGGTGAGGGTGTTGCGCGGGAACTGGGCGTTCCGGATGAGTGGATTGGCCTGACGA
TCCTGGCGCTGGGCACGTCGCTGCCGGAGATTGGCGCGGGGCTGGCGGCGGCGTTCCGCCAGCGGGGCGATGTGGTGGCG
GGCAATATCCTTGGCTCCAACGTGTTCAATATTCTGGGCGCGGGCGGCATTGTGGCGCTGTTCGGACCGTTCGAGGTGGC
GCCGCTGTTCCTGCAATACGACCATTGGGTCATGGGGATAACGGCGGTGCTGTTTGCGGGGCTGGTGATGCTGCGTGTGC
GGATGGGCCGGCTTCTGGGCGTGTTACTGCTGCTGATTTATGCGGCGTATATCTATGGGCTGGTGACGGGTACAAACCTG
ATGGCACTGGCGCAGATGGCGGGCCTATGA

Upstream 100 bases:

>100_bases
CCATCCTTCCCTGATCGCGATCGCCGCTATTGTTGTTGTGTTCGGCATCCTGAATCTCATAGAGTTCAAGCGTCTGGACT
AACCCCAAAGGGAGCAGGCG

Downstream 100 bases:

>100_bases
CCCCCAAAGGCGCGCTGGTGACGGGGGCAGGCGGACGCCTTGGCCGGGCCATGGCGCAGGCGCTGGGCGCCGATGGCTGG
GCGGTGGCGGTGCATTACCG

Product: sodium/calcium exchanger

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MPDPILLISLFGGLLLMALAGDLLVRGALGLGRAMGVSPLVAGIFIVGFGTSAPEMFISANAALNGNPGLAIGNIVGSNI
ANLLMVAAIPALFFPYRTGGAGQGRALFMLLLATAIWIGMTAIMPLDPIMGICFLLVLVGYAGFSIFAARHDEIAGKGAH
QADAVMLNPPVWRAIFYVPLGIAGLLYASRMIITGGEGVARELGVPDEWIGLTILALGTSLPEIGAGLAAAFRQRGDVVA
GNILGSNVFNILGAGGIVALFGPFEVAPLFLQYDHWVMGITAVLFAGLVMLRVRMGRLLGVLLLLIYAAYIYGLVTGTNL
MALAQMAGL

Sequences:

>Translated_329_residues
MPDPILLISLFGGLLLMALAGDLLVRGALGLGRAMGVSPLVAGIFIVGFGTSAPEMFISANAALNGNPGLAIGNIVGSNI
ANLLMVAAIPALFFPYRTGGAGQGRALFMLLLATAIWIGMTAIMPLDPIMGICFLLVLVGYAGFSIFAARHDEIAGKGAH
QADAVMLNPPVWRAIFYVPLGIAGLLYASRMIITGGEGVARELGVPDEWIGLTILALGTSLPEIGAGLAAAFRQRGDVVA
GNILGSNVFNILGAGGIVALFGPFEVAPLFLQYDHWVMGITAVLFAGLVMLRVRMGRLLGVLLLLIYAAYIYGLVTGTNL
MALAQMAGL
>Mature_328_residues
PDPILLISLFGGLLLMALAGDLLVRGALGLGRAMGVSPLVAGIFIVGFGTSAPEMFISANAALNGNPGLAIGNIVGSNIA
NLLMVAAIPALFFPYRTGGAGQGRALFMLLLATAIWIGMTAIMPLDPIMGICFLLVLVGYAGFSIFAARHDEIAGKGAHQ
ADAVMLNPPVWRAIFYVPLGIAGLLYASRMIITGGEGVARELGVPDEWIGLTILALGTSLPEIGAGLAAAFRQRGDVVAG
NILGSNVFNILGAGGIVALFGPFEVAPLFLQYDHWVMGITAVLFAGLVMLRVRMGRLLGVLLLLIYAAYIYGLVTGTNLM
ALAQMAGL

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1789587, Length=304, Percent_Identity=31.5789473684211, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 34079; Mature: 33947

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDPILLISLFGGLLLMALAGDLLVRGALGLGRAMGVSPLVAGIFIVGFGTSAPEMFISA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEECCCCCCCCEEEE
NAALNGNPGLAIGNIVGSNIANLLMVAAIPALFFPYRTGGAGQGRALFMLLLATAIWIGM
CCEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
TAIMPLDPIMGICFLLVLVGYAGFSIFAARHDEIAGKGAHQADAVMLNPPVWRAIFYVPL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHH
GIAGLLYASRMIITGGEGVARELGVPDEWIGLTILALGTSLPEIGAGLAAAFRQRGDVVA
HHHHHHHHHHHEEECCCCHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEE
GNILGSNVFNILGAGGIVALFGPFEVAPLFLQYDHWVMGITAVLFAGLVMLRVRMGRLLG
CHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLLLIYAAYIYGLVTGTNLMALAQMAGL
HHHHHHHHHHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure 
PDPILLISLFGGLLLMALAGDLLVRGALGLGRAMGVSPLVAGIFIVGFGTSAPEMFISA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEECCCCCCCCEEEE
NAALNGNPGLAIGNIVGSNIANLLMVAAIPALFFPYRTGGAGQGRALFMLLLATAIWIGM
CCEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
TAIMPLDPIMGICFLLVLVGYAGFSIFAARHDEIAGKGAHQADAVMLNPPVWRAIFYVPL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHH
GIAGLLYASRMIITGGEGVARELGVPDEWIGLTILALGTSLPEIGAGLAAAFRQRGDVVA
HHHHHHHHHHHEEECCCCHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEE
GNILGSNVFNILGAGGIVALFGPFEVAPLFLQYDHWVMGITAVLFAGLVMLRVRMGRLLG
CHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLLLIYAAYIYGLVTGTNLMALAQMAGL
HHHHHHHHHHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]