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The map label for this gene is mrdB [H]

Identifier: 114799677

GI number: 114799677

Start: 3193625

End: 3194776

Strand: Reverse

Name: mrdB [H]

Synonym: HNE_3025

Alternate gene names: 114799677

Gene position: 3194776-3193625 (Counterclockwise)

Preceding gene: 114798168

Following gene: 114799346

Centisome position: 86.23

GC content: 61.98

Gene sequence:

>1152_bases
GTGAGCTATACGGCCAACGCACCGCTTCTGCCGCGTTCGGATACATCCTGGTTTACCGAATGGCGCCGCACGCTGGACTG
GGGCCTGGTGGCCGGCGCGGTTCTGCTGCTGTTCATCGGTCTATTGATGTCGCTGGCGGCAGGGCCATCAGCCTCTACGC
GTATCGGCTATGACGATGCCTACCATTTCGTCTACCGGCAGGCCGCGCTCGCCGCCATCGGCTTCACGATCATGATAGTG
ATGAGCTTCCTGGACCGGAAATGGGCGCGCCGCGCGGCCACGATGATTTTTTTCGTCAGTCTGGGGATGATGGTCATCGT
GCTGGGCATCGGGCATGAGGCCAAGGGCGCGCAGCGATGGCTGCGCTTTGCCGGGTTTTCAATCCAGCCCAGCGAGATGG
TGAAACCGGCGCTGATCCTGCTGTGCGGCTGGCTGTTGGCCCAGCGGGAGCTTTATCCCAAAGGGCCGTGGGCGCTGATC
GCGTTCCTGTTCTATGCCGTCACACTCGGCCTGCTTCTGATGCAGCCGGATGTTGGCCAGTCAGCTCTGCTGACCTTTGC
TTTTATCATTACCTTTTTCGTGAGCGGGCTTCCCAAGCGCTGGGTTGCGGTGTTTGCCGTTGGCGGCGGGGCGCTGGCAT
TCTTCCTCTACAACCTGCTGCCCTATGTGAAGCGGCGCGTGGATATGATCTTCAATCCCGAGCCACTCGACAGCTACCAG
CTCGACAAGGCCGCTGAGGCCATCAGCCGGGGCGGTCTCTTCGGCGTTGGGCCGGGGGAGGGGCTCGTCAAGGCGCGCCT
GCCGGACGCGCACACCGACTTCATCTTCGCTGTGATGGCCGAAGAGTTTGGCCTCGTGGCAATCATCGTGCTGATGGCGA
TCTTTGCGATGATGGCGATTCGCGGCTTCCGCGCCTCGGCCCGCATCGAGGATGGCTATGCCCGCACGGCAGCGGCAGGT
CTCTTTACCCTGTTCAGCCTTCAGGCGGCGGTGAACATCGGCGTCAATCTGGCTGTCCTGCCGCCAACGGGCATGACACT
GCCTTTTGTTTCCTATGGAGGCTCCTCCATGGTGGGTATGGGATTGACGCTCGGCCTTGCGCTTGCTCTCGTCCGCGGAG
AAGGCACAAGGAGCCGAGGCCAGTATGGCTGA

Upstream 100 bases:

>100_bases
CCTGCGCCAGCTTTGACCAGTTCAAGGATTACGAACACCGGGGCGATGCGTTCCGCACGCTCGTGCACGGCATTGTGCCG
GCGAGCCTCAAGGTGACCGC

Downstream 100 bases:

>100_bases
CACCGGGACTGAAAAACTCGTCATCATTGCGGCCGGAGGCACCGGCGGTCACATGTTCCCGGCGCGCGCCTTTGCCGACG
AAATGCGCGCGCGTGGGTGG

Product: cell cycle protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MSYTANAPLLPRSDTSWFTEWRRTLDWGLVAGAVLLLFIGLLMSLAAGPSASTRIGYDDAYHFVYRQAALAAIGFTIMIV
MSFLDRKWARRAATMIFFVSLGMMVIVLGIGHEAKGAQRWLRFAGFSIQPSEMVKPALILLCGWLLAQRELYPKGPWALI
AFLFYAVTLGLLLMQPDVGQSALLTFAFIITFFVSGLPKRWVAVFAVGGGALAFFLYNLLPYVKRRVDMIFNPEPLDSYQ
LDKAAEAISRGGLFGVGPGEGLVKARLPDAHTDFIFAVMAEEFGLVAIIVLMAIFAMMAIRGFRASARIEDGYARTAAAG
LFTLFSLQAAVNIGVNLAVLPPTGMTLPFVSYGGSSMVGMGLTLGLALALVRGEGTRSRGQYG

Sequences:

>Translated_383_residues
MSYTANAPLLPRSDTSWFTEWRRTLDWGLVAGAVLLLFIGLLMSLAAGPSASTRIGYDDAYHFVYRQAALAAIGFTIMIV
MSFLDRKWARRAATMIFFVSLGMMVIVLGIGHEAKGAQRWLRFAGFSIQPSEMVKPALILLCGWLLAQRELYPKGPWALI
AFLFYAVTLGLLLMQPDVGQSALLTFAFIITFFVSGLPKRWVAVFAVGGGALAFFLYNLLPYVKRRVDMIFNPEPLDSYQ
LDKAAEAISRGGLFGVGPGEGLVKARLPDAHTDFIFAVMAEEFGLVAIIVLMAIFAMMAIRGFRASARIEDGYARTAAAG
LFTLFSLQAAVNIGVNLAVLPPTGMTLPFVSYGGSSMVGMGLTLGLALALVRGEGTRSRGQYG
>Mature_382_residues
SYTANAPLLPRSDTSWFTEWRRTLDWGLVAGAVLLLFIGLLMSLAAGPSASTRIGYDDAYHFVYRQAALAAIGFTIMIVM
SFLDRKWARRAATMIFFVSLGMMVIVLGIGHEAKGAQRWLRFAGFSIQPSEMVKPALILLCGWLLAQRELYPKGPWALIA
FLFYAVTLGLLLMQPDVGQSALLTFAFIITFFVSGLPKRWVAVFAVGGGALAFFLYNLLPYVKRRVDMIFNPEPLDSYQL
DKAAEAISRGGLFGVGPGEGLVKARLPDAHTDFIFAVMAEEFGLVAIIVLMAIFAMMAIRGFRASARIEDGYARTAAAGL
FTLFSLQAAVNIGVNLAVLPPTGMTLPFVSYGGSSMVGMGLTLGLALALVRGEGTRSRGQYG

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=368, Percent_Identity=32.8804347826087, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1786853, Length=314, Percent_Identity=34.0764331210191, Blast_Score=131, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41544; Mature: 41413

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYTANAPLLPRSDTSWFTEWRRTLDWGLVAGAVLLLFIGLLMSLAAGPSASTRIGYDDA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
YHFVYRQAALAAIGFTIMIVMSFLDRKWARRAATMIFFVSLGMMVIVLGIGHEAKGAQRW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LRFAGFSIQPSEMVKPALILLCGWLLAQRELYPKGPWALIAFLFYAVTLGLLLMQPDVGQ
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCH
SALLTFAFIITFFVSGLPKRWVAVFAVGGGALAFFLYNLLPYVKRRVDMIFNPEPLDSYQ
HHHHHHHHHHHHHHHCCCHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
LDKAAEAISRGGLFGVGPGEGLVKARLPDAHTDFIFAVMAEEFGLVAIIVLMAIFAMMAI
HHHHHHHHHCCCEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGFRASARIEDGYARTAAAGLFTLFSLQAAVNIGVNLAVLPPTGMTLPFVSYGGSSMVGM
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEECCCCCHHHH
GLTLGLALALVRGEGTRSRGQYG
HHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SYTANAPLLPRSDTSWFTEWRRTLDWGLVAGAVLLLFIGLLMSLAAGPSASTRIGYDDA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
YHFVYRQAALAAIGFTIMIVMSFLDRKWARRAATMIFFVSLGMMVIVLGIGHEAKGAQRW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LRFAGFSIQPSEMVKPALILLCGWLLAQRELYPKGPWALIAFLFYAVTLGLLLMQPDVGQ
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCH
SALLTFAFIITFFVSGLPKRWVAVFAVGGGALAFFLYNLLPYVKRRVDMIFNPEPLDSYQ
HHHHHHHHHHHHHHHCCCHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
LDKAAEAISRGGLFGVGPGEGLVKARLPDAHTDFIFAVMAEEFGLVAIIVLMAIFAMMAI
HHHHHHHHHCCCEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGFRASARIEDGYARTAAAGLFTLFSLQAAVNIGVNLAVLPPTGMTLPFVSYGGSSMVGM
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEECCCCCHHHH
GLTLGLALALVRGEGTRSRGQYG
HHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]