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The map label for this gene is murG

Identifier: 114799346

GI number: 114799346

Start: 3192532

End: 3193632

Strand: Reverse

Name: murG

Synonym: HNE_3024

Alternate gene names: 114799346

Gene position: 3193632-3192532 (Counterclockwise)

Preceding gene: 114799677

Following gene: 114798779

Centisome position: 86.2

GC content: 64.31

Gene sequence:

>1101_bases
ATGGCTGACACCGGGACTGAAAAACTCGTCATCATTGCGGCCGGAGGCACCGGCGGTCACATGTTCCCGGCGCGCGCCTT
TGCCGACGAAATGCGCGCGCGTGGGTGGAATACGGCGCTGATCTCAGATTCGCGCGGCCTGCGCTATGCGGCGGACTTCC
CGGCAGACTGGAAGGAAGAGATCGAGGCGGCCAGCCCGAATTTTCGCAAGCCCTGGACCGTTCCGGGCGCGGCGCTCAAG
ATCAATGCAGGCATTGCCCGTGCCCGGCGTCTGATGAAACAGCATCGCCCGGCGCTGGTTGCAGGCTTTGGCGGCTATCC
TGCCTTTCCGGCTCTGGCGGCGGCGCGGCGGCTCGGAGTGCCGATCATCATCCATGAGCAGAACGCCGTCCTCGGCCGGG
TGAACCGGCAGTTTGCAAAGCACGCACAGCTTGTCGCCAGCGGTTTTGAACGGCTCGACCGCTTGCCGCGCGGCTCGGCG
CATATGGTCATCGGCAACCCTGTGCGCGCGCCCATCATCGCGGCGGGGCAGGTGCCTTTTCCGCCTACGGACGGTACGCT
CAACATCTTCATTACAGGCGGCAGTCAGGGATCACGCATCATTGGCGAGATTGTGCCGCTGGCGATTGCCAACCATGTTG
CCCCGCCGCTGCGCGTGCGCCTCAAGGTGGTTCAGCAGGTGCGCGAGGAGCAGTTCGAAAGCGTCTCCAACCTCTACCGC
AGCGCCGGGATTGAGTGCGAGCTTGCTGCATTCTTCGGGGATATGCCTGAGCGTCTGGCTGCAGCTCATCTCGTGATTGC
CCGGTCGGGTGCGGGCACGGTCAGCGAACTGGCCACTGTCGGGCGCCCGTCGATCCTCATTCCGCTGGCGATTGCCATGG
ATGACCATCAGGCCGCGAATGCTGAGGCGCTGACCGCCATTGGCGCAGCCGACATGATCCTGGAAACAAATGCAACGCCC
AAATTGCTGGGCGAGTTGATCTCGGCCCGGCTGTCGGATGGCGCAGACCTGACGGCCCGCGCGGCTGCGGCGAAATCTGC
AGCCCGCCCGGATGCGGCCCAGAAACTGGCGGAAATGGCCGAAAGGATCGCAGAACTATGA

Upstream 100 bases:

>100_bases
TTTGTTTCCTATGGAGGCTCCTCCATGGTGGGTATGGGATTGACGCTCGGCCTTGCGCTTGCTCTCGTCCGCGGAGAAGG
CACAAGGAGCCGAGGCCAGT

Downstream 100 bases:

>100_bases
TCCGCAAGTCTGCTTTCATTGCCCTTATCTTTGGGGTGTTTCTCGCAATCGCCGAAATTGTGCGCAACTGGGGCGGCTGG
CAGCCCTGGCCCTTCTGGGT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MADTGTEKLVIIAAGGTGGHMFPARAFADEMRARGWNTALISDSRGLRYAADFPADWKEEIEAASPNFRKPWTVPGAALK
INAGIARARRLMKQHRPALVAGFGGYPAFPALAAARRLGVPIIIHEQNAVLGRVNRQFAKHAQLVASGFERLDRLPRGSA
HMVIGNPVRAPIIAAGQVPFPPTDGTLNIFITGGSQGSRIIGEIVPLAIANHVAPPLRVRLKVVQQVREEQFESVSNLYR
SAGIECELAAFFGDMPERLAAAHLVIARSGAGTVSELATVGRPSILIPLAIAMDDHQAANAEALTAIGAADMILETNATP
KLLGELISARLSDGADLTARAAAAKSAARPDAAQKLAEMAERIAEL

Sequences:

>Translated_366_residues
MADTGTEKLVIIAAGGTGGHMFPARAFADEMRARGWNTALISDSRGLRYAADFPADWKEEIEAASPNFRKPWTVPGAALK
INAGIARARRLMKQHRPALVAGFGGYPAFPALAAARRLGVPIIIHEQNAVLGRVNRQFAKHAQLVASGFERLDRLPRGSA
HMVIGNPVRAPIIAAGQVPFPPTDGTLNIFITGGSQGSRIIGEIVPLAIANHVAPPLRVRLKVVQQVREEQFESVSNLYR
SAGIECELAAFFGDMPERLAAAHLVIARSGAGTVSELATVGRPSILIPLAIAMDDHQAANAEALTAIGAADMILETNATP
KLLGELISARLSDGADLTARAAAAKSAARPDAAQKLAEMAERIAEL
>Mature_365_residues
ADTGTEKLVIIAAGGTGGHMFPARAFADEMRARGWNTALISDSRGLRYAADFPADWKEEIEAASPNFRKPWTVPGAALKI
NAGIARARRLMKQHRPALVAGFGGYPAFPALAAARRLGVPIIIHEQNAVLGRVNRQFAKHAQLVASGFERLDRLPRGSAH
MVIGNPVRAPIIAAGQVPFPPTDGTLNIFITGGSQGSRIIGEIVPLAIANHVAPPLRVRLKVVQQVREEQFESVSNLYRS
AGIECELAAFFGDMPERLAAAHLVIARSGAGTVSELATVGRPSILIPLAIAMDDHQAANAEALTAIGAADMILETNATPK
LLGELISARLSDGADLTARAAAAKSAARPDAAQKLAEMAERIAEL

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=372, Percent_Identity=31.989247311828, Blast_Score=152, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_HYPNA (Q0BXU2)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_761701.1
- ProteinModelPortal:   Q0BXU2
- SMR:   Q0BXU2
- STRING:   Q0BXU2
- GeneID:   4288116
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_3024
- NMPDR:   fig|228405.5.peg.2899
- TIGR:   HNE_3024
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   Q0BXU2
- ProtClustDB:   PRK00726
- BioCyc:   HNEP81032:HNE_3024-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38690; Mature: 38559

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTGTEKLVIIAAGGTGGHMFPARAFADEMRARGWNTALISDSRGLRYAADFPADWKEE
CCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEECCCCCCHHHH
IEAASPNFRKPWTVPGAALKINAGIARARRLMKQHRPALVAGFGGYPAFPALAAARRLGV
HHHCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCC
PIIIHEQNAVLGRVNRQFAKHAQLVASGFERLDRLPRGSAHMVIGNPVRAPIIAAGQVPF
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEECCCCC
PPTDGTLNIFITGGSQGSRIIGEIVPLAIANHVAPPLRVRLKVVQQVREEQFESVSNLYR
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SAGIECELAAFFGDMPERLAAAHLVIARSGAGTVSELATVGRPSILIPLAIAMDDHQAAN
HCCCCEEEHHHHCCCHHHHHHHHHEEEECCCCHHHHHHHCCCCCEEEEEEEEECCCCCCC
AEALTAIGAADMILETNATPKLLGELISARLSDGADLTARAAAAKSAARPDAAQKLAEMA
HHHHHHHCHHHHEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHH
ERIAEL
HHHHCC
>Mature Secondary Structure 
ADTGTEKLVIIAAGGTGGHMFPARAFADEMRARGWNTALISDSRGLRYAADFPADWKEE
CCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEECCCCCCHHHH
IEAASPNFRKPWTVPGAALKINAGIARARRLMKQHRPALVAGFGGYPAFPALAAARRLGV
HHHCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCC
PIIIHEQNAVLGRVNRQFAKHAQLVASGFERLDRLPRGSAHMVIGNPVRAPIIAAGQVPF
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEECCCCC
PPTDGTLNIFITGGSQGSRIIGEIVPLAIANHVAPPLRVRLKVVQQVREEQFESVSNLYR
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SAGIECELAAFFGDMPERLAAAHLVIARSGAGTVSELATVGRPSILIPLAIAMDDHQAAN
HCCCCEEEHHHHCCCHHHHHHHHHEEEECCCCHHHHHHHCCCCCEEEEEEEEECCCCCCC
AEALTAIGAADMILETNATPKLLGELISARLSDGADLTARAAAAKSAARPDAAQKLAEMA
HHHHHHHCHHHHEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHH
ERIAEL
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA