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The map label for this gene is putA [H]

Identifier: 114799148

GI number: 114799148

Start: 3145252

End: 3148386

Strand: Reverse

Name: putA [H]

Synonym: HNE_2988

Alternate gene names: 114799148

Gene position: 3148386-3145252 (Counterclockwise)

Preceding gene: 114799207

Following gene: 114798761

Centisome position: 84.98

GC content: 65.07

Gene sequence:

>3135_bases
ATGCCCGATACCGCTACGCAAACCGCTCTCGATTGGGACGCGCTCGACGCTCTGAAATTTACCGATGAGGAAGCTCTCCT
CGAAAGCCTCCTCAAGGAAGGCATTCTGCCCCCTTCGATCCGCGAGGGCGCCGTGCGCCGGGGCAGGGAACTGGTGATGT
CCGCCCGTGCCAAGGGCCGCCGCAAGGGCATGATGGAAAGCTTCCTGGAAGAGTTCGGCCTCTCCAATTCCGAAGGCCTC
GCCCTGATGTGCCTCGCTGAAGCCCTTCTGCGGGTGCCCGACGCCGAAACCAAGGACGACCTCATCGCCGAGAAAATCCG
CTCCGGCGACTGGGGCGCCCATAAGGGCCAGTCCGACAGCTGGCTGGTCAACGCCTCCACCTGGGGCCTGATGCTCACCG
GCCGCGTCATCGGCGCGCCGGAGAACGCCCATAAGGGCGCCGGCAATTTCGTCACCGGTCTCGTCCGCCAGTCCGGCGAG
CCCGTCATCCGCGCCGCCATGATGCAGGCCATGCGCATCATGGGCGAACAGTTCGTCCTTGGCCGGACGGTTTCAGAGGC
CCTTAAGCGCGGCCGCCGCATGGTCAAATCCGGCGAAGCGGCTCATTTCAGCTTCGACATGCTCGGCGAAGGCGCGCGCA
CCACGGCAGACGCAGACCGGTATTACAAAGCCTATCACGACGCCATCGCCGCCGTCGCGGCCGAAAAAGACCCCGCCCAG
CCGCCGGAAAAGGCCAATGGCGTCTCGGTCAAACTCTCCGCGCTCCATCCCCGCTACCTCGCCATCAAAGAGGCGCGCGT
GATGGCAGAGCTCTATCCGCGCGTGCTCTCCTTGTGCGAAGCGGCCGCCAAAGCCAATATCGGTCTCTGCCTCGATGCCG
AAGAAGCCCACCGCCTGGTCATCAGCCTGAAGATCTTCGAGCGCCTCGCCCGCGAGCCCTCCCTGAAAGACTGGACCGGC
CTCGGCCTCGCCGTACAGGCCTACCAGAAACGCGCCCGCGCCGTGATTGACCGACTCGCTGATCTGGCAAGACAAACGAA
CCGTCGCTTCATGGTCCGTCTCGTAAAAGGCGCCTATTGGGACAGCGAAATCAAGCATGCCCAGGTCGAAGGCTTCTCCA
ATTTCCCGGTCTTCACCACAAAGCAGGGTACGGACGTTCACTACCTCGTCTGCGCCAGGGCGATGCTCGCCGCGTCCCCG
GCCATCTATCCCGCCTTCGCCACCCACAACGCCCACAGCCTGGCAGCGGTTGATCTCCTCGCTGCCGAAGCCGGCGTCAC
CAATTTCGAATTCCAGCGCCTCCACGGCATGGGCGAGCCCCTTTATGAAGCCGCCGGCGCCGGAAACCGCGTCCGCGTCT
ATGCCCCCGTCGGCGCGCATGAAGACCTCCTGCCATATCTCGTTCGTCGCCTCCTGGAAAACGGCGCCAATACCAGCTTC
GTTCACTCTTTCCTTGATCCAGATGTGCCCGCAGAGCAGGTGGTGGCAGACCCCATCGCCAAGGTCGAGGCCGGCCCTCG
CCGCCATGCGCGCATCCCCACCCCGCCGCGTCTCTATGGCGCCGGCCGCCGCAACTCCGCCGGGCATGATCTCAGCCAGC
TTGACGTGCGCAAGAAGTTCGCCGCCGCGCTGAAAAGCCTCGATGATGGCCCGGCCTTTGCTGCAGGCGCCATCGTCTCA
GGAAAGCCCGAAACAGGCGGAGGCGAACTCGTCCGTATGCCTGCTGAAACCGGCCGCGCCCTCGGCGCCCTGAAGGAGGC
CGATGCCGACGAGATTGACCGCGCGCTTGACGCGGCCACGAAATTCCAGCCGGAATGGGATCAACTCGGCGGCTCCAAAC
GTGCCGAACACCTCCGCGCCATGGGCGACGTCCTGGAGGCAAACGCTGCCCAGCTCATCGCCCTGATGTCCCGCGAAGCG
GGCAAGACGCTTCCTGACGGCATCGCCGAAGTGCGCGAAGCGGTCGACTTCTGCCGCTACTATGCTCAGCAGGCGGAGCA
GGATTTTGCCGCCCCCGTGCGCCTTCCGGGCCCCACGGGCGAAACCAACCATCTCTCCCTGCATGGCCGCGGCGTCTTCT
GTTGCATCAGCCCGTGGAACTTTCCGCTCGCCATCTTCACCGGCCAGATCGCGGCTGCGCTCGCTGCGGGCAACACGGTC
GTCGCCAAGCCCGCCGAACAGACGGGCCTCACCGCCTTTGAGGCCGTGCGCCTTTTCCACAAGGCCGGTCTGCCCGGCGA
TGCGCTGCACCTCCTGCCGGGCAGGGGCGAAACCGTCGGCGCCGCGCTGACGGGCGACCTTCGCGTCTCCGGCGTCTGCT
TCACCGGCGGCACCTCAACCGCCCGGATGATCAACCGCACGCTCGCAGGCCGGGACGGCCCCATCATTCCGCTGATCGCA
GAGACCGGCGGCCTCAACGGTCTCTTCGTCGATACAACGGCGCTCAGGGAGCAGGTGATCGACGACATCATCATCTCTGC
CTTCGGCTCGGCCGGCCAGCGTTGCTCGGCCCTGCGCATTGCTTTCGTGCCCAATGCGACCGCCGATCATCTCATCGACG
GCCTCATCGGCGCCATGAACGAGCTGGCCCTTGGCGATCCTGCCCTTCCGCAAACCGATACCGGCCCGGTGATCGATGCC
GACGCCCGCAAGGCGCTGGAAGCTCATATGGAGCGCATGACCCGCGAAGCGAAAGTCCTCCACCAGCTCGACGCCGGAAA
GCTTGGCGAAGAGGGCTATGGCTTCGGCCCGGCCCTGGTGGAACTCTCCTCGCTCGACCAGATCAGCGAAGAAACCTTCG
GCCCTGTCCTGCATATCCTGCGCTATGATCCGGATAATGTCGCCGTCCTCGCCAGTGCCCTGAAAGCCAAAGGATACGGC
CTCACCCTCGGCATCCACTCGCGCCTGGAAAGTTTCCACAATGCCGTCAAGACGGCCTGCCCGGTCGGCAACACCTATGT
GAACCGCTCGATGATCGGCGCGGTCGTCGGTGTCCAGCCCTTTGGCGGGGAAGGGCTCTCGGGCACTGGCCCCAAGGCAG
GGGGCCCACATTATCTCCATCGTTTCGCCACGGAGCGCGTGGTAAGTGTCAACATCACCGCCCAGGGCGGCGATCCGGAA
CTGCTCAGCCTCTAA

Upstream 100 bases:

>100_bases
GCGCTGTTTTGAGGCACTCCCCTGATGGGGGTATTCTTGTGCGCAGGCTAAGGTATAAGCGGCAGATTATTGCCCCGGCC
CTGCCAGACGGACCCTCTCC

Downstream 100 bases:

>100_bases
GGAACGAACCGCATGAAACGCCTTCTCCTCACCGCTTCGATGGCTGCGCTCCTGCTGGCAGCGTGCGCCCCCAAAACGGA
AACGCCCGCCGATGCAGGCG

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1044; Mature: 1043

Protein sequence:

>1044_residues
MPDTATQTALDWDALDALKFTDEEALLESLLKEGILPPSIREGAVRRGRELVMSARAKGRRKGMMESFLEEFGLSNSEGL
ALMCLAEALLRVPDAETKDDLIAEKIRSGDWGAHKGQSDSWLVNASTWGLMLTGRVIGAPENAHKGAGNFVTGLVRQSGE
PVIRAAMMQAMRIMGEQFVLGRTVSEALKRGRRMVKSGEAAHFSFDMLGEGARTTADADRYYKAYHDAIAAVAAEKDPAQ
PPEKANGVSVKLSALHPRYLAIKEARVMAELYPRVLSLCEAAAKANIGLCLDAEEAHRLVISLKIFERLAREPSLKDWTG
LGLAVQAYQKRARAVIDRLADLARQTNRRFMVRLVKGAYWDSEIKHAQVEGFSNFPVFTTKQGTDVHYLVCARAMLAASP
AIYPAFATHNAHSLAAVDLLAAEAGVTNFEFQRLHGMGEPLYEAAGAGNRVRVYAPVGAHEDLLPYLVRRLLENGANTSF
VHSFLDPDVPAEQVVADPIAKVEAGPRRHARIPTPPRLYGAGRRNSAGHDLSQLDVRKKFAAALKSLDDGPAFAAGAIVS
GKPETGGGELVRMPAETGRALGALKEADADEIDRALDAATKFQPEWDQLGGSKRAEHLRAMGDVLEANAAQLIALMSREA
GKTLPDGIAEVREAVDFCRYYAQQAEQDFAAPVRLPGPTGETNHLSLHGRGVFCCISPWNFPLAIFTGQIAAALAAGNTV
VAKPAEQTGLTAFEAVRLFHKAGLPGDALHLLPGRGETVGAALTGDLRVSGVCFTGGTSTARMINRTLAGRDGPIIPLIA
ETGGLNGLFVDTTALREQVIDDIIISAFGSAGQRCSALRIAFVPNATADHLIDGLIGAMNELALGDPALPQTDTGPVIDA
DARKALEAHMERMTREAKVLHQLDAGKLGEEGYGFGPALVELSSLDQISEETFGPVLHILRYDPDNVAVLASALKAKGYG
LTLGIHSRLESFHNAVKTACPVGNTYVNRSMIGAVVGVQPFGGEGLSGTGPKAGGPHYLHRFATERVVSVNITAQGGDPE
LLSL

Sequences:

>Translated_1044_residues
MPDTATQTALDWDALDALKFTDEEALLESLLKEGILPPSIREGAVRRGRELVMSARAKGRRKGMMESFLEEFGLSNSEGL
ALMCLAEALLRVPDAETKDDLIAEKIRSGDWGAHKGQSDSWLVNASTWGLMLTGRVIGAPENAHKGAGNFVTGLVRQSGE
PVIRAAMMQAMRIMGEQFVLGRTVSEALKRGRRMVKSGEAAHFSFDMLGEGARTTADADRYYKAYHDAIAAVAAEKDPAQ
PPEKANGVSVKLSALHPRYLAIKEARVMAELYPRVLSLCEAAAKANIGLCLDAEEAHRLVISLKIFERLAREPSLKDWTG
LGLAVQAYQKRARAVIDRLADLARQTNRRFMVRLVKGAYWDSEIKHAQVEGFSNFPVFTTKQGTDVHYLVCARAMLAASP
AIYPAFATHNAHSLAAVDLLAAEAGVTNFEFQRLHGMGEPLYEAAGAGNRVRVYAPVGAHEDLLPYLVRRLLENGANTSF
VHSFLDPDVPAEQVVADPIAKVEAGPRRHARIPTPPRLYGAGRRNSAGHDLSQLDVRKKFAAALKSLDDGPAFAAGAIVS
GKPETGGGELVRMPAETGRALGALKEADADEIDRALDAATKFQPEWDQLGGSKRAEHLRAMGDVLEANAAQLIALMSREA
GKTLPDGIAEVREAVDFCRYYAQQAEQDFAAPVRLPGPTGETNHLSLHGRGVFCCISPWNFPLAIFTGQIAAALAAGNTV
VAKPAEQTGLTAFEAVRLFHKAGLPGDALHLLPGRGETVGAALTGDLRVSGVCFTGGTSTARMINRTLAGRDGPIIPLIA
ETGGLNGLFVDTTALREQVIDDIIISAFGSAGQRCSALRIAFVPNATADHLIDGLIGAMNELALGDPALPQTDTGPVIDA
DARKALEAHMERMTREAKVLHQLDAGKLGEEGYGFGPALVELSSLDQISEETFGPVLHILRYDPDNVAVLASALKAKGYG
LTLGIHSRLESFHNAVKTACPVGNTYVNRSMIGAVVGVQPFGGEGLSGTGPKAGGPHYLHRFATERVVSVNITAQGGDPE
LLSL
>Mature_1043_residues
PDTATQTALDWDALDALKFTDEEALLESLLKEGILPPSIREGAVRRGRELVMSARAKGRRKGMMESFLEEFGLSNSEGLA
LMCLAEALLRVPDAETKDDLIAEKIRSGDWGAHKGQSDSWLVNASTWGLMLTGRVIGAPENAHKGAGNFVTGLVRQSGEP
VIRAAMMQAMRIMGEQFVLGRTVSEALKRGRRMVKSGEAAHFSFDMLGEGARTTADADRYYKAYHDAIAAVAAEKDPAQP
PEKANGVSVKLSALHPRYLAIKEARVMAELYPRVLSLCEAAAKANIGLCLDAEEAHRLVISLKIFERLAREPSLKDWTGL
GLAVQAYQKRARAVIDRLADLARQTNRRFMVRLVKGAYWDSEIKHAQVEGFSNFPVFTTKQGTDVHYLVCARAMLAASPA
IYPAFATHNAHSLAAVDLLAAEAGVTNFEFQRLHGMGEPLYEAAGAGNRVRVYAPVGAHEDLLPYLVRRLLENGANTSFV
HSFLDPDVPAEQVVADPIAKVEAGPRRHARIPTPPRLYGAGRRNSAGHDLSQLDVRKKFAAALKSLDDGPAFAAGAIVSG
KPETGGGELVRMPAETGRALGALKEADADEIDRALDAATKFQPEWDQLGGSKRAEHLRAMGDVLEANAAQLIALMSREAG
KTLPDGIAEVREAVDFCRYYAQQAEQDFAAPVRLPGPTGETNHLSLHGRGVFCCISPWNFPLAIFTGQIAAALAAGNTVV
AKPAEQTGLTAFEAVRLFHKAGLPGDALHLLPGRGETVGAALTGDLRVSGVCFTGGTSTARMINRTLAGRDGPIIPLIAE
TGGLNGLFVDTTALREQVIDDIIISAFGSAGQRCSALRIAFVPNATADHLIDGLIGAMNELALGDPALPQTDTGPVIDAD
ARKALEAHMERMTREAKVLHQLDAGKLGEEGYGFGPALVELSSLDQISEETFGPVLHILRYDPDNVAVLASALKAKGYGL
TLGIHSRLESFHNAVKTACPVGNTYVNRSMIGAVVGVQPFGGEGLSGTGPKAGGPHYLHRFATERVVSVNITAQGGDPEL
LSL

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777736, Length=475, Percent_Identity=30.9473684210526, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI25777734, Length=475, Percent_Identity=30.9473684210526, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI238859541, Length=475, Percent_Identity=30.9473684210526, Blast_Score=177, Evalue=5e-44,
Organism=Homo sapiens, GI21361176, Length=468, Percent_Identity=28.6324786324786, Blast_Score=163, Evalue=1e-39,
Organism=Homo sapiens, GI25777724, Length=471, Percent_Identity=29.5116772823779, Blast_Score=156, Evalue=1e-37,
Organism=Homo sapiens, GI25777732, Length=465, Percent_Identity=27.9569892473118, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI153266822, Length=479, Percent_Identity=27.1398747390397, Blast_Score=150, Evalue=9e-36,
Organism=Homo sapiens, GI25777730, Length=448, Percent_Identity=27.6785714285714, Blast_Score=147, Evalue=4e-35,
Organism=Homo sapiens, GI25777728, Length=430, Percent_Identity=29.0697674418605, Blast_Score=140, Evalue=7e-33,
Organism=Homo sapiens, GI12007648, Length=462, Percent_Identity=26.6233766233766, Blast_Score=137, Evalue=5e-32,
Organism=Homo sapiens, GI21614513, Length=416, Percent_Identity=28.125, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI4507229, Length=460, Percent_Identity=28.0434782608696, Blast_Score=130, Evalue=6e-30,
Organism=Homo sapiens, GI238814322, Length=432, Percent_Identity=25.2314814814815, Blast_Score=129, Evalue=2e-29,
Organism=Homo sapiens, GI188035924, Length=452, Percent_Identity=26.5486725663717, Blast_Score=125, Evalue=3e-28,
Organism=Homo sapiens, GI310128103, Length=452, Percent_Identity=26.5486725663717, Blast_Score=124, Evalue=4e-28,
Organism=Homo sapiens, GI310128093, Length=442, Percent_Identity=26.6968325791855, Blast_Score=124, Evalue=5e-28,
Organism=Homo sapiens, GI115387104, Length=499, Percent_Identity=25.250501002004, Blast_Score=122, Evalue=2e-27,
Organism=Homo sapiens, GI25777721, Length=473, Percent_Identity=27.061310782241, Blast_Score=120, Evalue=6e-27,
Organism=Homo sapiens, GI25777726, Length=471, Percent_Identity=27.3885350318471, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI310128091, Length=397, Percent_Identity=27.2040302267003, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI25952152, Length=255, Percent_Identity=30.5882352941176, Blast_Score=106, Evalue=9e-23,
Organism=Homo sapiens, GI310128087, Length=260, Percent_Identity=28.4615384615385, Blast_Score=98, Evalue=5e-20,
Organism=Homo sapiens, GI11095441, Length=375, Percent_Identity=25.3333333333333, Blast_Score=97, Evalue=9e-20,
Organism=Homo sapiens, GI310128099, Length=214, Percent_Identity=28.0373831775701, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI310128101, Length=205, Percent_Identity=28.2926829268293, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI310128089, Length=336, Percent_Identity=25.8928571428571, Blast_Score=72, Evalue=4e-12,
Organism=Escherichia coli, GI1787250, Length=1025, Percent_Identity=47.609756097561, Blast_Score=880, Evalue=0.0,
Organism=Escherichia coli, GI1787684, Length=459, Percent_Identity=32.0261437908497, Blast_Score=170, Evalue=3e-43,
Organism=Escherichia coli, GI1789015, Length=485, Percent_Identity=30.3092783505155, Blast_Score=161, Evalue=2e-40,
Organism=Escherichia coli, GI1788042, Length=462, Percent_Identity=30.5194805194805, Blast_Score=156, Evalue=6e-39,
Organism=Escherichia coli, GI1787715, Length=467, Percent_Identity=32.1199143468951, Blast_Score=150, Evalue=6e-37,
Organism=Escherichia coli, GI87081896, Length=488, Percent_Identity=28.0737704918033, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI1786504, Length=466, Percent_Identity=26.8240343347639, Blast_Score=130, Evalue=5e-31,
Organism=Escherichia coli, GI1787558, Length=455, Percent_Identity=27.2527472527473, Blast_Score=129, Evalue=1e-30,
Organism=Escherichia coli, GI87082295, Length=453, Percent_Identity=28.2560706401766, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI87081926, Length=461, Percent_Identity=25.5965292841649, Blast_Score=107, Evalue=4e-24,
Organism=Escherichia coli, GI1787653, Length=348, Percent_Identity=23.2758620689655, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17534447, Length=482, Percent_Identity=29.6680497925311, Blast_Score=160, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI133930964, Length=467, Percent_Identity=28.9079229122056, Blast_Score=156, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI115532534, Length=397, Percent_Identity=31.9899244332494, Blast_Score=148, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17562198, Length=468, Percent_Identity=28.4188034188034, Blast_Score=147, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI25144435, Length=492, Percent_Identity=28.4552845528455, Blast_Score=145, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI25143874, Length=459, Percent_Identity=27.0152505446623, Blast_Score=144, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI25143876, Length=459, Percent_Identity=27.0152505446623, Blast_Score=143, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17551164, Length=527, Percent_Identity=26.3757115749526, Blast_Score=140, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI115534176, Length=470, Percent_Identity=27.2340425531915, Blast_Score=138, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI32564736, Length=443, Percent_Identity=29.1196388261851, Blast_Score=131, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17534119, Length=461, Percent_Identity=26.4642082429501, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI32564151, Length=416, Percent_Identity=27.6442307692308, Blast_Score=115, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71995606, Length=441, Percent_Identity=24.9433106575964, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71995613, Length=398, Percent_Identity=24.6231155778894, Blast_Score=107, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI71986308, Length=385, Percent_Identity=25.4545454545455, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71990744, Length=306, Percent_Identity=27.1241830065359, Blast_Score=87, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17564084, Length=415, Percent_Identity=23.6144578313253, Blast_Score=66, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6323822, Length=484, Percent_Identity=26.0330578512397, Blast_Score=145, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6320917, Length=446, Percent_Identity=28.47533632287, Blast_Score=144, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6319478, Length=494, Percent_Identity=26.5182186234818, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6323821, Length=465, Percent_Identity=25.8064516129032, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324950, Length=447, Percent_Identity=27.0693512304251, Blast_Score=133, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6325196, Length=464, Percent_Identity=25.8620689655172, Blast_Score=131, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6321826, Length=486, Percent_Identity=27.1604938271605, Blast_Score=131, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6321828, Length=483, Percent_Identity=26.2939958592132, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24668425, Length=519, Percent_Identity=28.9017341040462, Blast_Score=169, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24668417, Length=519, Percent_Identity=28.9017341040462, Blast_Score=169, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24668413, Length=519, Percent_Identity=28.9017341040462, Blast_Score=169, Evalue=1e-41,
Organism=Drosophila melanogaster, GI281362580, Length=472, Percent_Identity=29.0254237288136, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI62472918, Length=472, Percent_Identity=29.0254237288136, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI62472926, Length=472, Percent_Identity=29.0254237288136, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI62472936, Length=472, Percent_Identity=29.0254237288136, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI21356737, Length=472, Percent_Identity=29.0254237288136, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24585660, Length=463, Percent_Identity=26.133909287257, Blast_Score=140, Evalue=5e-33,
Organism=Drosophila melanogaster, GI20129399, Length=464, Percent_Identity=26.5086206896552, Blast_Score=138, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24650465, Length=445, Percent_Identity=26.5168539325843, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24666674, Length=488, Percent_Identity=25.6147540983607, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28574525, Length=482, Percent_Identity=24.6887966804979, Blast_Score=130, Evalue=5e-30,
Organism=Drosophila melanogaster, GI28571798, Length=479, Percent_Identity=26.7223382045929, Blast_Score=129, Evalue=9e-30,
Organism=Drosophila melanogaster, GI28571796, Length=479, Percent_Identity=26.7223382045929, Blast_Score=129, Evalue=9e-30,
Organism=Drosophila melanogaster, GI28571794, Length=479, Percent_Identity=26.7223382045929, Blast_Score=129, Evalue=9e-30,
Organism=Drosophila melanogaster, GI28571806, Length=479, Percent_Identity=26.7223382045929, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571802, Length=479, Percent_Identity=26.7223382045929, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571800, Length=479, Percent_Identity=26.7223382045929, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24638876, Length=375, Percent_Identity=27.2, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24638878, Length=375, Percent_Identity=27.2, Blast_Score=100, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 111577; Mature: 111445

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDTATQTALDWDALDALKFTDEEALLESLLKEGILPPSIREGAVRRGRELVMSARAKGR
CCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RKGMMESFLEEFGLSNSEGLALMCLAEALLRVPDAETKDDLIAEKIRSGDWGAHKGQSDS
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
WLVNASTWGLMLTGRVIGAPENAHKGAGNFVTGLVRQSGEPVIRAAMMQAMRIMGEQFVL
EEEECCCCCEEEECEEECCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
GRTVSEALKRGRRMVKSGEAAHFSFDMLGEGARTTADADRYYKAYHDAIAAVAAEKDPAQ
HHHHHHHHHHHHHHHHCCCCCEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
PPEKANGVSVKLSALHPRYLAIKEARVMAELYPRVLSLCEAAAKANIGLCLDAEEAHRLV
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHH
ISLKIFERLAREPSLKDWTGLGLAVQAYQKRARAVIDRLADLARQTNRRFMVRLVKGAYW
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DSEIKHAQVEGFSNFPVFTTKQGTDVHYLVCARAMLAASPAIYPAFATHNAHSLAAVDLL
CCHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHH
AAEAGVTNFEFQRLHGMGEPLYEAAGAGNRVRVYAPVGAHEDLLPYLVRRLLENGANTSF
HHHCCCCCHHHHHHHCCCCHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCHHH
VHSFLDPDVPAEQVVADPIAKVEAGPRRHARIPTPPRLYGAGRRNSAGHDLSQLDVRKKF
HHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
AAALKSLDDGPAFAAGAIVSGKPETGGGELVRMPAETGRALGALKEADADEIDRALDAAT
HHHHHCCCCCCCCCCCCEECCCCCCCCCCEEECCHHHHHHHHHHHHCCHHHHHHHHHHHH
KFQPEWDQLGGSKRAEHLRAMGDVLEANAAQLIALMSREAGKTLPDGIAEVREAVDFCRY
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
YAQQAEQDFAAPVRLPGPTGETNHLSLHGRGVFCCISPWNFPLAIFTGQIAAALAAGNTV
HHHHHHHHCCCCEECCCCCCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHCCCEE
VAKPAEQTGLTAFEAVRLFHKAGLPGDALHLLPGRGETVGAALTGDLRVSGVCFTGGTST
EECCCHHHCHHHHHHHHHHHHCCCCCCCEEECCCCCCEECEEEECCEEEEEEEEECCCHH
ARMINRTLAGRDGPIIPLIAETGGLNGLFVDTTALREQVIDDIIISAFGSAGQRCSALRI
HHHHHHHHCCCCCCEEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
AFVPNATADHLIDGLIGAMNELALGDPALPQTDTGPVIDADARKALEAHMERMTREAKVL
EECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHH
HQLDAGKLGEEGYGFGPALVELSSLDQISEETFGPVLHILRYDPDNVAVLASALKAKGYG
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHCCCCE
LTLGIHSRLESFHNAVKTACPVGNTYVNRSMIGAVVGVQPFGGEGLSGTGPKAGGPHYLH
EEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
RFATERVVSVNITAQGGDPELLSL
HHHHCEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
PDTATQTALDWDALDALKFTDEEALLESLLKEGILPPSIREGAVRRGRELVMSARAKGR
CCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RKGMMESFLEEFGLSNSEGLALMCLAEALLRVPDAETKDDLIAEKIRSGDWGAHKGQSDS
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
WLVNASTWGLMLTGRVIGAPENAHKGAGNFVTGLVRQSGEPVIRAAMMQAMRIMGEQFVL
EEEECCCCCEEEECEEECCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
GRTVSEALKRGRRMVKSGEAAHFSFDMLGEGARTTADADRYYKAYHDAIAAVAAEKDPAQ
HHHHHHHHHHHHHHHHCCCCCEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
PPEKANGVSVKLSALHPRYLAIKEARVMAELYPRVLSLCEAAAKANIGLCLDAEEAHRLV
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHH
ISLKIFERLAREPSLKDWTGLGLAVQAYQKRARAVIDRLADLARQTNRRFMVRLVKGAYW
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DSEIKHAQVEGFSNFPVFTTKQGTDVHYLVCARAMLAASPAIYPAFATHNAHSLAAVDLL
CCHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHH
AAEAGVTNFEFQRLHGMGEPLYEAAGAGNRVRVYAPVGAHEDLLPYLVRRLLENGANTSF
HHHCCCCCHHHHHHHCCCCHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCHHH
VHSFLDPDVPAEQVVADPIAKVEAGPRRHARIPTPPRLYGAGRRNSAGHDLSQLDVRKKF
HHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
AAALKSLDDGPAFAAGAIVSGKPETGGGELVRMPAETGRALGALKEADADEIDRALDAAT
HHHHHCCCCCCCCCCCCEECCCCCCCCCCEEECCHHHHHHHHHHHHCCHHHHHHHHHHHH
KFQPEWDQLGGSKRAEHLRAMGDVLEANAAQLIALMSREAGKTLPDGIAEVREAVDFCRY
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
YAQQAEQDFAAPVRLPGPTGETNHLSLHGRGVFCCISPWNFPLAIFTGQIAAALAAGNTV
HHHHHHHHCCCCEECCCCCCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHCCCEE
VAKPAEQTGLTAFEAVRLFHKAGLPGDALHLLPGRGETVGAALTGDLRVSGVCFTGGTST
EECCCHHHCHHHHHHHHHHHHCCCCCCCEEECCCCCCEECEEEECCEEEEEEEEECCCHH
ARMINRTLAGRDGPIIPLIAETGGLNGLFVDTTALREQVIDDIIISAFGSAGQRCSALRI
HHHHHHHHCCCCCCEEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
AFVPNATADHLIDGLIGAMNELALGDPALPQTDTGPVIDADARKALEAHMERMTREAKVL
EECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHH
HQLDAGKLGEEGYGFGPALVELSSLDQISEETFGPVLHILRYDPDNVAVLASALKAKGYG
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHCCCCE
LTLGIHSRLESFHNAVKTACPVGNTYVNRSMIGAVVGVQPFGGEGLSGTGPKAGGPHYLH
EEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
RFATERVVSVNITAQGGDPELLSL
HHHHCEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]