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The map label for this gene is tal

Identifier: 114799016

GI number: 114799016

Start: 3402695

End: 3403345

Strand: Reverse

Name: tal

Synonym: HNE_3235

Alternate gene names: 114799016

Gene position: 3403345-3402695 (Counterclockwise)

Preceding gene: 114798680

Following gene: 114799777

Centisome position: 91.86

GC content: 60.06

Gene sequence:

>651_bases
ATGAAGTTCTTCGTCGACACCGCCGACACCCAAGACATTGCCGACCTTGCCGCCACGGGTCTGATTGACGGGGTGACCAC
CAATCCCTCGCTGATCGCAAAGTCTGGCCGCCCGTTTGCCGAGGTGATTGCTGAAATCTGCGCCCTCACGGACGGGCCGG
TGAGCGCCGAAGTTGTGGCGATCGATTTTGACGGCATGATGCGCGAGGGCCGAAAGCTGGCCAAGATTGCAGACAATGTC
ACCGTCAAGCTGCCCTTGACGCTTGAGGGGCTGAAGGCCTGCAAGGCGCTGACCTCTGATGGCATTGATGTGAACGTCAC
GCTCTGCTTCTCGGCCAATCAGGCGTTGCTGGCGGCCAAGGCGGGCGCAACCTTCATTTCGCCGTTCATCGGGCGCCTCG
ACGATATTCACATCGACGGTATGGAGCTGATCCAGGAGATCCGCCAGATCTATGACAATTACATGTTCGAGACGGAAATC
CTTGCCGCCTCGATCCGTAGCCCCAACCATGTGCGGCTCTGCGCGCTGGCCGGCGCGGACGTGATGACGGCGCCGCCGGC
AGTGATCCGTAGTCTTGTCAGCCATCCGTTGACGGATAAAGGTCTTGAGACCTTCCTTGCGGACGCGAAGAAGGCCGGCA
TCGAGGTCTGA

Upstream 100 bases:

>100_bases
CTACCACCCCGACGATCTGGCCAAACATGGCTTTGCCTATACCTCCATCGGCCGGCCTGCCGTATAGTCCTCCCCAAGCA
GCGCATCAGGAAGCAAGCTC

Downstream 100 bases:

>100_bases
TCCCTATGGCGGAGGCAGAAGGCCCGCGCGGCCGTGTCCTGATCATTGCCGGCTCCGATTCCGGGGGCGGGGCGGGCATT
CAAGCCGACATCAAGACCGT

Product: putative transaldolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MKFFVDTADTQDIADLAATGLIDGVTTNPSLIAKSGRPFAEVIAEICALTDGPVSAEVVAIDFDGMMREGRKLAKIADNV
TVKLPLTLEGLKACKALTSDGIDVNVTLCFSANQALLAAKAGATFISPFIGRLDDIHIDGMELIQEIRQIYDNYMFETEI
LAASIRSPNHVRLCALAGADVMTAPPAVIRSLVSHPLTDKGLETFLADAKKAGIEV

Sequences:

>Translated_216_residues
MKFFVDTADTQDIADLAATGLIDGVTTNPSLIAKSGRPFAEVIAEICALTDGPVSAEVVAIDFDGMMREGRKLAKIADNV
TVKLPLTLEGLKACKALTSDGIDVNVTLCFSANQALLAAKAGATFISPFIGRLDDIHIDGMELIQEIRQIYDNYMFETEI
LAASIRSPNHVRLCALAGADVMTAPPAVIRSLVSHPLTDKGLETFLADAKKAGIEV
>Mature_216_residues
MKFFVDTADTQDIADLAATGLIDGVTTNPSLIAKSGRPFAEVIAEICALTDGPVSAEVVAIDFDGMMREGRKLAKIADNV
TVKLPLTLEGLKACKALTSDGIDVNVTLCFSANQALLAAKAGATFISPFIGRLDDIHIDGMELIQEIRQIYDNYMFETEI
LAASIRSPNHVRLCALAGADVMTAPPAVIRSLVSHPLTDKGLETFLADAKKAGIEV

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 3B subfamily

Homologues:

Organism=Homo sapiens, GI5803187, Length=175, Percent_Identity=33.1428571428571, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI87081788, Length=214, Percent_Identity=32.2429906542056, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790382, Length=214, Percent_Identity=35.5140186915888, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788807, Length=203, Percent_Identity=30.0492610837438, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1786189, Length=171, Percent_Identity=32.7485380116959, Blast_Score=83, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25153750, Length=189, Percent_Identity=32.8042328042328, Blast_Score=84, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6321480, Length=221, Percent_Identity=30.316742081448, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323386, Length=198, Percent_Identity=30.8080808080808, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45549185, Length=172, Percent_Identity=31.9767441860465, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TAL_HYPNA (Q0BX85)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_761908.1
- ProteinModelPortal:   Q0BX85
- SMR:   Q0BX85
- STRING:   Q0BX85
- GeneID:   4287533
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_3235
- NMPDR:   fig|228405.5.peg.3097
- TIGR:   HNE_3235
- eggNOG:   COG0176
- HOGENOM:   HBG533000
- OMA:   IHKNIVI
- PhylomeDB:   Q0BX85
- ProtClustDB:   CLSK2531928
- BioCyc:   HNEP81032:HNE_3235-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00494
- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004731
- InterPro:   IPR022999
- InterPro:   IPR018225
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10683
- TIGRFAMs:   TIGR00875

Pfam domain/function: PF00923 Transaldolase

EC number: =2.2.1.2

Molecular weight: Translated: 22948; Mature: 22948

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS01054 TRANSALDOLASE_1; PS00958 TRANSALDOLASE_2

Important sites: ACT_SITE 83-83

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFFVDTADTQDIADLAATGLIDGVTTNPSLIAKSGRPFAEVIAEICALTDGPVSAEVVA
CEEEECCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCEEEEE
IDFDGMMREGRKLAKIADNVTVKLPLTLEGLKACKALTSDGIDVNVTLCFSANQALLAAK
EECCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHCCCCEEEEEEEEECCCEEEEHH
AGATFISPFIGRLDDIHIDGMELIQEIRQIYDNYMFETEILAASIRSPNHVRLCALAGAD
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
VMTAPPAVIRSLVSHPLTDKGLETFLADAKKAGIEV
CCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKFFVDTADTQDIADLAATGLIDGVTTNPSLIAKSGRPFAEVIAEICALTDGPVSAEVVA
CEEEECCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCEEEEE
IDFDGMMREGRKLAKIADNVTVKLPLTLEGLKACKALTSDGIDVNVTLCFSANQALLAAK
EECCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHCCCCEEEEEEEEECCCEEEEHH
AGATFISPFIGRLDDIHIDGMELIQEIRQIYDNYMFETEILAASIRSPNHVRLCALAGAD
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
VMTAPPAVIRSLVSHPLTDKGLETFLADAKKAGIEV
CCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA