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The map label for this gene is rkpK [H]

Identifier: 114798680

GI number: 114798680

Start: 3403379

End: 3404689

Strand: Reverse

Name: rkpK [H]

Synonym: HNE_3236

Alternate gene names: 114798680

Gene position: 3404689-3403379 (Counterclockwise)

Preceding gene: 114798536

Following gene: 114799016

Centisome position: 91.89

GC content: 59.57

Gene sequence:

>1311_bases
ATGCGTGTTGCGATCATCGGTACGGGCTATGTTGGCCTGGTTTCGGGCGCCTGTTTTGCCGATTTCGGCCATACGGTCAC
CTGCGTCGACAAGGACGCTGCCAAAATCGAGAAGTTGAAGAATGGCATCATGCCGATCTTCGAGCCTGGTCTCGAAAGCC
TGGTTGCGAAGAATGTGAAAGAGGAGCGTCTCTTCTTCACGACGGAGGCGCGCGAAGCGATCCAGGATGCCGATGCGGTG
TTTATCGCCGTGGGCACCCCCTCCCGGCGGGGCGACGGGCATGCCGACCTCTCCTATGTGTACGGCGCTGCCGAAGAGAT
TGCCCAGCTGATGGACGGGTTCACAGTCGTTGTCACCAAATCGACTGTGCCGGTGGGCACCGGAGACGAGGTAGAGGAAA
TCATCCGCAAGACCCGGCCCGACGCTGACTTTGCGGTGGTTTCAAATCCCGAATTCCTGCGGGAAGGCGCGGCGATCAAG
GACTTCAAGATCCCTGACCGTGTGGTTGTCGGCACTGATGATGAGCGCGCGCGCGATGTCATGCGCGAGCTTTACCGGCC
GCTTTTCCTCAATGAGACGCCGATCCTGTTCACCTCACGGCGCACGTCCGAGCTGATCAAATATGCGGCTAACGCCTTCC
TCGCGGTGAAAATCACCTTCATCAACGAGATGGCCGATTTGTGCGAAAAGGTCGGTGCCAACGTTCAGGAGGTCTCCCGC
GGGATTGGCCTGGATGGCCGCATCGGCGCGAAATTCCTCAATGCCGGTCCGGGCTATGGCGGCTCGTGTTTCCCGAAAGA
CACCCTCGCCCTGACCAAGACGGCGAATGACTATGGTAGCCCCGTGCGCATTGTGGACACGGTGATCGAGGTCAACGCAG
ACCGCAAGAAAGCCATGGCAGACAAGGTCATCGCCGCGATGGGCGGGAGTGTGACCGGCAAGACGATCGGCGTGCTCGGC
CTCGCCTTCAAACAGAATACGGACGATATGCGCGACGCGCCATCTCTGGATATTCTGCCCGCGCTGCAGGCAGCCGGGGC
GCGGGTTGTCGCGTATGACCCTGAAGCAATGAAGGAAGCGGCGCATCTGCTGAAAGACATCGAGTTTGTCGACAGCCCCT
ATAAGGCCGTCGACGGGGCGGACGCGATGGTCATCATTACCGAATGGGATCAGTTTCGCGCGCTTGACCTCAACCGCCTC
AAAACCGCGATGAAGGGCAATGTCGTCGTCGACCTGCGTAACATCTACCACCCCGACGATCTGGCCAAACATGGCTTTGC
CTATACCTCCATCGGCCGGCCTGCCGTATAG

Upstream 100 bases:

>100_bases
TCAACCCATCTTTCGCTGCGGCAATCTCCTCTTGATTCTGCTGCCTAAAAAATGCACCCCGCGAGCATCTGCCTCGCTTC
AAGAGTGTTGAGGGAATCCC

Downstream 100 bases:

>100_bases
TCCTCCCCAAGCAGCGCATCAGGAAGCAAGCTCATGAAGTTCTTCGTCGACACCGCCGACACCCAAGACATTGCCGACCT
TGCCGCCACGGGTCTGATTG

Product: UDP-glucose dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MRVAIIGTGYVGLVSGACFADFGHTVTCVDKDAAKIEKLKNGIMPIFEPGLESLVAKNVKEERLFFTTEAREAIQDADAV
FIAVGTPSRRGDGHADLSYVYGAAEEIAQLMDGFTVVVTKSTVPVGTGDEVEEIIRKTRPDADFAVVSNPEFLREGAAIK
DFKIPDRVVVGTDDERARDVMRELYRPLFLNETPILFTSRRTSELIKYAANAFLAVKITFINEMADLCEKVGANVQEVSR
GIGLDGRIGAKFLNAGPGYGGSCFPKDTLALTKTANDYGSPVRIVDTVIEVNADRKKAMADKVIAAMGGSVTGKTIGVLG
LAFKQNTDDMRDAPSLDILPALQAAGARVVAYDPEAMKEAAHLLKDIEFVDSPYKAVDGADAMVIITEWDQFRALDLNRL
KTAMKGNVVVDLRNIYHPDDLAKHGFAYTSIGRPAV

Sequences:

>Translated_436_residues
MRVAIIGTGYVGLVSGACFADFGHTVTCVDKDAAKIEKLKNGIMPIFEPGLESLVAKNVKEERLFFTTEAREAIQDADAV
FIAVGTPSRRGDGHADLSYVYGAAEEIAQLMDGFTVVVTKSTVPVGTGDEVEEIIRKTRPDADFAVVSNPEFLREGAAIK
DFKIPDRVVVGTDDERARDVMRELYRPLFLNETPILFTSRRTSELIKYAANAFLAVKITFINEMADLCEKVGANVQEVSR
GIGLDGRIGAKFLNAGPGYGGSCFPKDTLALTKTANDYGSPVRIVDTVIEVNADRKKAMADKVIAAMGGSVTGKTIGVLG
LAFKQNTDDMRDAPSLDILPALQAAGARVVAYDPEAMKEAAHLLKDIEFVDSPYKAVDGADAMVIITEWDQFRALDLNRL
KTAMKGNVVVDLRNIYHPDDLAKHGFAYTSIGRPAV
>Mature_436_residues
MRVAIIGTGYVGLVSGACFADFGHTVTCVDKDAAKIEKLKNGIMPIFEPGLESLVAKNVKEERLFFTTEAREAIQDADAV
FIAVGTPSRRGDGHADLSYVYGAAEEIAQLMDGFTVVVTKSTVPVGTGDEVEEIIRKTRPDADFAVVSNPEFLREGAAIK
DFKIPDRVVVGTDDERARDVMRELYRPLFLNETPILFTSRRTSELIKYAANAFLAVKITFINEMADLCEKVGANVQEVSR
GIGLDGRIGAKFLNAGPGYGGSCFPKDTLALTKTANDYGSPVRIVDTVIEVNADRKKAMADKVIAAMGGSVTGKTIGVLG
LAFKQNTDDMRDAPSLDILPALQAAGARVVAYDPEAMKEAAHLLKDIEFVDSPYKAVDGADAMVIITEWDQFRALDLNRL
KTAMKGNVVVDLRNIYHPDDLAKHGFAYTSIGRPAV

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=461, Percent_Identity=38.177874186551, Blast_Score=287, Evalue=2e-77,
Organism=Homo sapiens, GI296040438, Length=362, Percent_Identity=38.9502762430939, Blast_Score=235, Evalue=6e-62,
Organism=Homo sapiens, GI296040443, Length=311, Percent_Identity=39.5498392282958, Blast_Score=203, Evalue=3e-52,
Organism=Escherichia coli, GI1788340, Length=370, Percent_Identity=31.0810810810811, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI48994968, Length=433, Percent_Identity=29.5612009237875, Blast_Score=154, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17560350, Length=464, Percent_Identity=37.9310344827586, Blast_Score=278, Evalue=5e-75,
Organism=Drosophila melanogaster, GI17136908, Length=463, Percent_Identity=37.3650107991361, Blast_Score=284, Evalue=8e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 47175; Mature: 47175

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVAIIGTGYVGLVSGACFADFGHTVTCVDKDAAKIEKLKNGIMPIFEPGLESLVAKNVK
CEEEEEECCHHHHHCCHHHHHCCCEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
EERLFFTTEAREAIQDADAVFIAVGTPSRRGDGHADLSYVYGAAEEIAQLMDGFTVVVTK
HHHEEEEHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHCCHHHHHHHHCCEEEEEEE
STVPVGTGDEVEEIIRKTRPDADFAVVSNPEFLREGAAIKDFKIPDRVVVGTDDERARDV
CCCCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHCCCCEECCCCCCEEEECCCCHHHHHH
MRELYRPLFLNETPILFTSRRTSELIKYAANAFLAVKITFINEMADLCEKVGANVQEVSR
HHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCHHHHHH
GIGLDGRIGAKFLNAGPGYGGSCFPKDTLALTKTANDYGSPVRIVDTVIEVNADRKKAMA
CCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHEEHHHHHCCCCHHHHHH
DKVIAAMGGSVTGKTIGVLGLAFKQNTDDMRDAPSLDILPALQAAGARVVAYDPEAMKEA
HHHHHHHCCCCCCCHHHHEEEEECCCCCHHHCCCCCCHHHHHHHCCCEEEEECHHHHHHH
AHLLKDIEFVDSPYKAVDGADAMVIITEWDQFRALDLNRLKTAMKGNVVVDLRNIYHPDD
HHHHHHHHHHCCCHHHCCCCCEEEEEEECCCHHHCCHHHHHHHHCCCEEEEEHHCCCCHH
LAKHGFAYTSIGRPAV
HHHCCCEEECCCCCCC
>Mature Secondary Structure
MRVAIIGTGYVGLVSGACFADFGHTVTCVDKDAAKIEKLKNGIMPIFEPGLESLVAKNVK
CEEEEEECCHHHHHCCHHHHHCCCEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
EERLFFTTEAREAIQDADAVFIAVGTPSRRGDGHADLSYVYGAAEEIAQLMDGFTVVVTK
HHHEEEEHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHCCHHHHHHHHCCEEEEEEE
STVPVGTGDEVEEIIRKTRPDADFAVVSNPEFLREGAAIKDFKIPDRVVVGTDDERARDV
CCCCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHCCCCEECCCCCCEEEECCCCHHHHHH
MRELYRPLFLNETPILFTSRRTSELIKYAANAFLAVKITFINEMADLCEKVGANVQEVSR
HHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCHHHHHH
GIGLDGRIGAKFLNAGPGYGGSCFPKDTLALTKTANDYGSPVRIVDTVIEVNADRKKAMA
CCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHEEHHHHHCCCCHHHHHH
DKVIAAMGGSVTGKTIGVLGLAFKQNTDDMRDAPSLDILPALQAAGARVVAYDPEAMKEA
HHHHHHHCCCCCCCHHHHEEEEECCCCCHHHCCCCCCHHHHHHHCCCEEEEECHHHHHHH
AHLLKDIEFVDSPYKAVDGADAMVIITEWDQFRALDLNRLKTAMKGNVVVDLRNIYHPDD
HHHHHHHHHHCCCHHHCCCCCEEEEEEECCCHHHCCHHHHHHHHCCCEEEEEHHCCCCHH
LAKHGFAYTSIGRPAV
HHHCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9765575; 11481430 [H]