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The map label for this gene is linC [H]

Identifier: 114798104

GI number: 114798104

Start: 952974

End: 954296

Strand: Reverse

Name: linC [H]

Synonym: HNE_0938

Alternate gene names: 114798104

Gene position: 954296-952974 (Counterclockwise)

Preceding gene: 114798162

Following gene: 114797130

Centisome position: 25.76

GC content: 57.29

Gene sequence:

>1323_bases
ATGAATGTCACTGAAACCTATCAGGTCGAGAGCCCTCCCAAGGAGCCAAAATTCGGCAAGGCTTACGCCCTGACACCCCC
ACTGGATCTTACCCAGCCCACCGTTTTCTCCGAACATGGCGGCTATACGTACGCCGATTTCGCGAAGATGCGGGAGAAGG
CGCCCGTGATGTGGCACCCGGAAGAATATGGCGCGGGCTTCTGGGCCGTTACCTCATATGATCTCGTCAAAAAGGTCGAA
CTGACACCGGAAACGTTCTCGTCGCAAAAAGGCGGCATCCTGATGAATTACGGCATGGAGGGCGTTCCACGCCATCCGCT
GCTGCATTCTTCGTCGCTGAACTCGCTGATCAACCTCGACCGGCCCTATCACACGCCCCTGCGCATGGAGCATATGGCTT
ATTTCCGCGCCGATTTTGTTGCGGAACTGAGAAAGCGGGTGGATGTGGAAGTAAACCGCCTGCTCGACACGATGGAGGCC
CAAGGCCCCGTTGTAGACATGGTGGAAATGTTCTCGGCGGAACTACCCCTCTTTACATTGTGTGAAATCCTGGGTGTTCC
ACCGGCTGACCGCCCGAAGCTGGTCCATTGGATGCACTTCCTCGAGACTTCGCAATACCAGGCCCAGCAGGAAGGCCTCG
GGAATGTATCCCAAGAGCAGATCATGGCATTCCTGAACGAGATTCAGGCCATGTTTGAATATGGCCGCTACCTGCTAGAG
GAGCGCCGCAAAAATCCGCAGCCGGATCTTCTCTCGGCCATTGCCAATGTGCAGGTTGATGGCAAGCCGCTGTCGCCGGA
ATTCCTTGATGGCTCTTGGCTGCTCATTGTCTTCGCGGGCAACGATACGACGCGTAACTCGCTCTCAGGGACGATGCGCC
TGCTGACGGAAAATCCCGAGCTGCGCGAACAGTTGAAAGAAAAGCCCGAGCGCTTTCCTAACTTCGTGCACGAAGCCATC
CGCATGGTGACGCCGGTGACCTATATGCGCCGCACGGCCACTCAGGACACAGAGCTGGGCGACCAGAAGATTGCCGAAGG
CGAAAAGGTGATCATGTATTACGCGGCCGCCAACCGCGATCCGTCGAAATTCGAGAACCCGGACCGTTTCGATATCGACC
GCTCCAACGCCAAGGAACATCTCGCCTTTGGTCACGGGCCGCATGTGTGCCTCGGCCAGCGGGTCGCCAACATGCAGCTG
GAGTCTGCTTACCGGCAAATCCTGTCGCGTTTCCCGAATGTGCGCTGGACCGGCGAGCAGACGATTGCGCCCAACAACTT
CGTTCACGCGATCTCGTCCCTGATGGTGGATCTGGGCAAATGA

Upstream 100 bases:

>100_bases
CCCGGTACGGTACAGGTTCTGATACTTGGGGGCGCTTCCGGGCGCCCCACCCTGCCCCTGCCCTCCCGAACAGATATTGT
GAGCTACGCCCATGACCTTC

Downstream 100 bases:

>100_bases
GCGTTGTTCTGCGCGAAGACCGGGACGGCCTGGCCATCCTGACGCTCAACCGGCCGGACAAGCTGAACTCGCTGACCGTC
GGCATGTTCGAAGAACTGCG

Product: cytochrome P450 family protein

Products: NA

Alternate protein names: Cytochrome P450 111; Cytochrome P450lin [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MNVTETYQVESPPKEPKFGKAYALTPPLDLTQPTVFSEHGGYTYADFAKMREKAPVMWHPEEYGAGFWAVTSYDLVKKVE
LTPETFSSQKGGILMNYGMEGVPRHPLLHSSSLNSLINLDRPYHTPLRMEHMAYFRADFVAELRKRVDVEVNRLLDTMEA
QGPVVDMVEMFSAELPLFTLCEILGVPPADRPKLVHWMHFLETSQYQAQQEGLGNVSQEQIMAFLNEIQAMFEYGRYLLE
ERRKNPQPDLLSAIANVQVDGKPLSPEFLDGSWLLIVFAGNDTTRNSLSGTMRLLTENPELREQLKEKPERFPNFVHEAI
RMVTPVTYMRRTATQDTELGDQKIAEGEKVIMYYAAANRDPSKFENPDRFDIDRSNAKEHLAFGHGPHVCLGQRVANMQL
ESAYRQILSRFPNVRWTGEQTIAPNNFVHAISSLMVDLGK

Sequences:

>Translated_440_residues
MNVTETYQVESPPKEPKFGKAYALTPPLDLTQPTVFSEHGGYTYADFAKMREKAPVMWHPEEYGAGFWAVTSYDLVKKVE
LTPETFSSQKGGILMNYGMEGVPRHPLLHSSSLNSLINLDRPYHTPLRMEHMAYFRADFVAELRKRVDVEVNRLLDTMEA
QGPVVDMVEMFSAELPLFTLCEILGVPPADRPKLVHWMHFLETSQYQAQQEGLGNVSQEQIMAFLNEIQAMFEYGRYLLE
ERRKNPQPDLLSAIANVQVDGKPLSPEFLDGSWLLIVFAGNDTTRNSLSGTMRLLTENPELREQLKEKPERFPNFVHEAI
RMVTPVTYMRRTATQDTELGDQKIAEGEKVIMYYAAANRDPSKFENPDRFDIDRSNAKEHLAFGHGPHVCLGQRVANMQL
ESAYRQILSRFPNVRWTGEQTIAPNNFVHAISSLMVDLGK
>Mature_440_residues
MNVTETYQVESPPKEPKFGKAYALTPPLDLTQPTVFSEHGGYTYADFAKMREKAPVMWHPEEYGAGFWAVTSYDLVKKVE
LTPETFSSQKGGILMNYGMEGVPRHPLLHSSSLNSLINLDRPYHTPLRMEHMAYFRADFVAELRKRVDVEVNRLLDTMEA
QGPVVDMVEMFSAELPLFTLCEILGVPPADRPKLVHWMHFLETSQYQAQQEGLGNVSQEQIMAFLNEIQAMFEYGRYLLE
ERRKNPQPDLLSAIANVQVDGKPLSPEFLDGSWLLIVFAGNDTTRNSLSGTMRLLTENPELREQLKEKPERFPNFVHEAI
RMVTPVTYMRRTATQDTELGDQKIAEGEKVIMYYAAANRDPSKFENPDRFDIDRSNAKEHLAFGHGPHVCLGQRVANMQL
ESAYRQILSRFPNVRWTGEQTIAPNNFVHAISSLMVDLGK

Specific function: Catalyzes the 8-methyl hydroxylation of linalool [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Homo sapiens, GI261278370, Length=178, Percent_Identity=26.9662921348315, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI195972896, Length=178, Percent_Identity=26.9662921348315, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI195972898, Length=178, Percent_Identity=26.9662921348315, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI261278372, Length=178, Percent_Identity=26.9662921348315, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4503231, Length=175, Percent_Identity=27.4285714285714, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI4503211, Length=230, Percent_Identity=23.4782608695652, Blast_Score=65, Evalue=1e-10,
Organism=Drosophila melanogaster, GI17933518, Length=189, Percent_Identity=25.3968253968254, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24642101, Length=154, Percent_Identity=25.974025974026, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355669, Length=202, Percent_Identity=26.2376237623762, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19920736, Length=222, Percent_Identity=25.6756756756757, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24646122, Length=201, Percent_Identity=27.363184079602, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: =1.14.99.28 [H]

Molecular weight: Translated: 50176; Mature: 50176

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVTETYQVESPPKEPKFGKAYALTPPLDLTQPTVFSEHGGYTYADFAKMREKAPVMWHP
CCCCCCEECCCCCCCCCCCCEEEECCCCCCCCCCEECCCCCEEHHHHHHHHHCCCCEECC
EEYGAGFWAVTSYDLVKKVELTPETFSSQKGGILMNYGMEGVPRHPLLHSSSLNSLINLD
HHHCCCEEEEEHHHHHHHEECCCHHHCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHCCC
RPYHTPLRMEHMAYFRADFVAELRKRVDVEVNRLLDTMEAQGPVVDMVEMFSAELPLFTL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHH
CEILGVPPADRPKLVHWMHFLETSQYQAQQEGLGNVSQEQIMAFLNEIQAMFEYGRYLLE
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ERRKNPQPDLLSAIANVQVDGKPLSPEFLDGSWLLIVFAGNDTTRNSLSGTMRLLTENPE
HHHCCCCHHHHHHHHCCEECCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCHH
LREQLKEKPERFPNFVHEAIRMVTPVTYMRRTATQDTELGDQKIAEGEKVIMYYAAANRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCEEEEEEEECCCC
PSKFENPDRFDIDRSNAKEHLAFGHGPHVCLGQRVANMQLESAYRQILSRFPNVRWTGEQ
CHHCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCC
TIAPNNFVHAISSLMVDLGK
CCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNVTETYQVESPPKEPKFGKAYALTPPLDLTQPTVFSEHGGYTYADFAKMREKAPVMWHP
CCCCCCEECCCCCCCCCCCCEEEECCCCCCCCCCEECCCCCEEHHHHHHHHHCCCCEECC
EEYGAGFWAVTSYDLVKKVELTPETFSSQKGGILMNYGMEGVPRHPLLHSSSLNSLINLD
HHHCCCEEEEEHHHHHHHEECCCHHHCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHCCC
RPYHTPLRMEHMAYFRADFVAELRKRVDVEVNRLLDTMEAQGPVVDMVEMFSAELPLFTL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHH
CEILGVPPADRPKLVHWMHFLETSQYQAQQEGLGNVSQEQIMAFLNEIQAMFEYGRYLLE
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ERRKNPQPDLLSAIANVQVDGKPLSPEFLDGSWLLIVFAGNDTTRNSLSGTMRLLTENPE
HHHCCCCHHHHHHHHCCEECCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCHH
LREQLKEKPERFPNFVHEAIRMVTPVTYMRRTATQDTELGDQKIAEGEKVIMYYAAANRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCEEEEEEEECCCC
PSKFENPDRFDIDRSNAKEHLAFGHGPHVCLGQRVANMQLESAYRQILSRFPNVRWTGEQ
CHHCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCC
TIAPNNFVHAISSLMVDLGK
CCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8376348; 2295633; 3813557; 2578028; 1610873; 12237225 [H]