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The map label for this gene is crt [H]

Identifier: 114797130

GI number: 114797130

Start: 952234

End: 952977

Strand: Reverse

Name: crt [H]

Synonym: HNE_0937

Alternate gene names: 114797130

Gene position: 952977-952234 (Counterclockwise)

Preceding gene: 114798104

Following gene: 114797759

Centisome position: 25.72

GC content: 62.77

Gene sequence:

>744_bases
ATGAGCGTTGTTCTGCGCGAAGACCGGGACGGCCTGGCCATCCTGACGCTCAACCGGCCGGACAAGCTGAACTCGCTGAC
CGTCGGCATGTTCGAAGAACTGCGCGGGCATGTGAGCGATCTTTACAAGGATGAGTCCATCGGCTGCGTTGTCCTGCGCG
GGGCGGGGCGATGTTTCTCTGCCGGCCATGATCTGGCCGACATTGCCGAGGGCGAGAAAGTGCCCTCGCGCGGCTGGCAT
TCGGAAACCCTGCGCCTGCTGGAGCGCCTGCCCAAGCCTGTCATCGCGGCGGTGCATGGTCATTGCTATACCGGCGCACT
GGAAGTGGCGCTTGCGGCAGATTTCATCATTGCCGCCGAAAGCGCGAAGTTTGGCGACACGCATGCCAAATGGGCGCTTA
CCCCGATCTGGGGGATGAGCCAGCGCCTGCCCCGGCGCGTGGGCATCGCCACCGCCAAGCGCCTGATGTTTACCGCCGAA
ATGTTCGGCGCAGCAGAGGCGCTGCGCATCGGCCTGGCAGAACACGTTGTTCCCGATGCGGAATTTGACGCCGCCATCGA
CAAAATGGCAGGCCAGATCCTCGCCAATTCGCCGTTCAGCCACGCGGCCAACAAGCGCCTGCTGGAAGCGACTGACGCGC
GGGATATGGACAGCGGCCTGCAATGGGAAATACTTAACAATGAGGGCGTAGGCCCTGACATGCAGGCTCGCATCGGCGCA
TTCATGGGGAAAGGCCGAAGCTGA

Upstream 100 bases:

>100_bases
TCCTGTCGCGTTTCCCGAATGTGCGCTGGACCGGCGAGCAGACGATTGCGCCCAACAACTTCGTTCACGCGATCTCGTCC
CTGATGGTGGATCTGGGCAA

Downstream 100 bases:

>100_bases
GCCCGAACAAGGGGACTGAACTTGGCTGACTTTCTGATCCGGCGCAGCAATCTGCGCGACACTTCCTGGGTAAACACGCC
GCTGCCGCCACTGGCAGATG

Product: enoyl-CoA hydratase/isomerase family protein

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MSVVLREDRDGLAILTLNRPDKLNSLTVGMFEELRGHVSDLYKDESIGCVVLRGAGRCFSAGHDLADIAEGEKVPSRGWH
SETLRLLERLPKPVIAAVHGHCYTGALEVALAADFIIAAESAKFGDTHAKWALTPIWGMSQRLPRRVGIATAKRLMFTAE
MFGAAEALRIGLAEHVVPDAEFDAAIDKMAGQILANSPFSHAANKRLLEATDARDMDSGLQWEILNNEGVGPDMQARIGA
FMGKGRS

Sequences:

>Translated_247_residues
MSVVLREDRDGLAILTLNRPDKLNSLTVGMFEELRGHVSDLYKDESIGCVVLRGAGRCFSAGHDLADIAEGEKVPSRGWH
SETLRLLERLPKPVIAAVHGHCYTGALEVALAADFIIAAESAKFGDTHAKWALTPIWGMSQRLPRRVGIATAKRLMFTAE
MFGAAEALRIGLAEHVVPDAEFDAAIDKMAGQILANSPFSHAANKRLLEATDARDMDSGLQWEILNNEGVGPDMQARIGA
FMGKGRS
>Mature_246_residues
SVVLREDRDGLAILTLNRPDKLNSLTVGMFEELRGHVSDLYKDESIGCVVLRGAGRCFSAGHDLADIAEGEKVPSRGWHS
ETLRLLERLPKPVIAAVHGHCYTGALEVALAADFIIAAESAKFGDTHAKWALTPIWGMSQRLPRRVGIATAKRLMFTAEM
FGAAEALRIGLAEHVVPDAEFDAAIDKMAGQILANSPFSHAANKRLLEATDARDMDSGLQWEILNNEGVGPDMQARIGAF
MGKGRS

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=182, Percent_Identity=35.7142857142857, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI194097323, Length=222, Percent_Identity=29.7297297297297, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI4502327, Length=228, Percent_Identity=32.8947368421053, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI31542718, Length=194, Percent_Identity=26.8041237113402, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI157694516, Length=192, Percent_Identity=27.6041666666667, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI213417737, Length=192, Percent_Identity=27.6041666666667, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI20127408, Length=174, Percent_Identity=29.3103448275862, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI68989263, Length=203, Percent_Identity=26.6009852216749, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI37594469, Length=192, Percent_Identity=28.125, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI37594471, Length=185, Percent_Identity=28.6486486486486, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1787659, Length=254, Percent_Identity=30.3149606299213, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI221142681, Length=226, Percent_Identity=33.6283185840708, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI87082183, Length=249, Percent_Identity=29.3172690763052, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787660, Length=253, Percent_Identity=31.2252964426877, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788597, Length=219, Percent_Identity=32.4200913242009, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1788682, Length=179, Percent_Identity=31.2849162011173, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790281, Length=174, Percent_Identity=30.4597701149425, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17540714, Length=218, Percent_Identity=34.4036697247706, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI25145438, Length=216, Percent_Identity=32.4074074074074, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17536985, Length=243, Percent_Identity=29.2181069958848, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17554946, Length=217, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17549921, Length=216, Percent_Identity=31.0185185185185, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17534483, Length=228, Percent_Identity=27.1929824561404, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560910, Length=199, Percent_Identity=28.643216080402, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17535521, Length=266, Percent_Identity=25.9398496240602, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17540306, Length=179, Percent_Identity=27.3743016759777, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17508951, Length=187, Percent_Identity=32.0855614973262, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17558304, Length=180, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25144276, Length=187, Percent_Identity=32.0855614973262, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508953, Length=187, Percent_Identity=32.0855614973262, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25141363, Length=166, Percent_Identity=30.1204819277108, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=212, Percent_Identity=28.3018867924528, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24653139, Length=224, Percent_Identity=37.5, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI20129971, Length=213, Percent_Identity=31.924882629108, Blast_Score=110, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24653477, Length=213, Percent_Identity=31.924882629108, Blast_Score=110, Evalue=6e-25,
Organism=Drosophila melanogaster, GI19920382, Length=181, Percent_Identity=31.4917127071823, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357171, Length=183, Percent_Identity=27.3224043715847, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19922422, Length=200, Percent_Identity=25, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583165, Length=229, Percent_Identity=24.4541484716157, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19921018, Length=257, Percent_Identity=24.5136186770428, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24650670, Length=182, Percent_Identity=29.6703296703297, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI45550169, Length=229, Percent_Identity=23.5807860262009, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI19921000, Length=177, Percent_Identity=30.5084745762712, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24583077, Length=177, Percent_Identity=30.5084745762712, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24583079, Length=177, Percent_Identity=30.5084745762712, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 26774; Mature: 26643

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVLREDRDGLAILTLNRPDKLNSLTVGMFEELRGHVSDLYKDESIGCVVLRGAGRCFS
CCEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHH
AGHDLADIAEGEKVPSRGWHSETLRLLERLPKPVIAAVHGHCYTGALEVALAADFIIAAE
CCCCHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHEEEC
SAKFGDTHAKWALTPIWGMSQRLPRRVGIATAKRLMFTAEMFGAAEALRIGLAEHVVPDA
CCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EFDAAIDKMAGQILANSPFSHAANKRLLEATDARDMDSGLQWEILNNEGVGPDMQARIGA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHH
FMGKGRS
HHCCCCC
>Mature Secondary Structure 
SVVLREDRDGLAILTLNRPDKLNSLTVGMFEELRGHVSDLYKDESIGCVVLRGAGRCFS
CEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHH
AGHDLADIAEGEKVPSRGWHSETLRLLERLPKPVIAAVHGHCYTGALEVALAADFIIAAE
CCCCHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHEEEC
SAKFGDTHAKWALTPIWGMSQRLPRRVGIATAKRLMFTAEMFGAAEALRIGLAEHVVPDA
CCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EFDAAIDKMAGQILANSPFSHAANKRLLEATDARDMDSGLQWEILNNEGVGPDMQARIGA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHH
FMGKGRS
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]