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The map label for this gene is yggW [C]

Identifier: 114797411

GI number: 114797411

Start: 3464637

End: 3465809

Strand: Reverse

Name: yggW [C]

Synonym: HNE_3309

Alternate gene names: 114797411

Gene position: 3465809-3464637 (Counterclockwise)

Preceding gene: 114800076

Following gene: 114799736

Centisome position: 93.54

GC content: 64.62

Gene sequence:

>1173_bases
ATGACCCAGGTTTTTGCGCCTTTCGGCCCGCATTTCGGCTTCGGCCTGTATATCCATTGGCCCTATTGCACGCGGGTCTG
CCCTTATTGCGACTTCAACGTCTACGCCGCCAAGGACCGGGCCACCGATCCGCTGGTGACGGCGATTGCCGATGACATTC
GCGTTCACCGCCGCAAGCTGCCCGAGCATGGCGCGCTCGATACGGTATATTTTGGCGGCGGCACGCCCGCCTTGCTGAGG
CCAGAGCAGGTGGCTGAAATCCTGAAGGCGGCGTCTGAAACATTCGGCATCAAGGACGGCGCTGAAATAACGCTGGAGGC
CAATCCGAACGATGTTCTGAAAGCGGACCTTCTGGCGCTGCGCCGGGCGGGCGTCACGCGCCTGTCCATCGGCGTCCAGT
CGATGCGGGATTCGGCGCTGGCATTCCTGGGGCGCGATCATACCGCCGAGGCGGGCGGCGAGGCGGTGAAGCGCGCGCTG
AAAGTGTTCGACACGATTTCCATGGACCTGATCTATGCCAGGCCCGGACAATCCCCGGCAAACTGGGAAGCCGAGCTCGC
CGATGCGCTGGCGCTCGGCGCGCCGCATCTCTCGCTTTATGAGCTGACCTTCGAGCCGGCAACGGCGTTTGGTAAGGCAG
CCCAGCGCGGCGAGATTGTTCCGATGCCGGATGATGCGCAGGCCGATCTTTATGAGCTGACCCAGCAGATGACGCGCGAT
GCCGGCATGCCTGCCTATGAAGTGTCCAATCACGCGGCCTCGCCCGCGCATCAATCACGCCACAATCTGATCTACTGGCG
GGGTGGCGACTGGATCGGCGCGGGGCCTGGCGCGCATGGCCGCGTTTCGGTTGCGGGCAACCGGTATGCCACCGAGGCCG
AGCGGCGCCCGGAAGGCTATATGGCCGGCATGCAGATGTTGCAGGAGGGCTGGGCCGACGCGGCAAAGCTGCCCCCGCTC
GACATTGCGCGGGAGATCCTGGCGATGGGCCTGCGCGCCGCAGAGGGCGTGGACCTGCGCCGGGTGGAGATTGTCAGCGG
CAAAAAGGTCTCGCGGGAGAAGATTGGCGTTTTCACCGAGCAGGGCTGGGTGAAACTTCAGGGGTCGGAGCTTTCGTTGA
CGGAGAGCGGGCGGCTGCTGGCCGACGCGCTGACGTCTCAATTGGCGCCCTGA

Upstream 100 bases:

>100_bases
AGGGCGAGACGATGACGTTTGGTGAAATGGACCCCGCGCGCAAACACGCGATGAGCCACCGGGCCCGCGCGGTCGAGAAG
CTGCGCGCGGCGCTGCTCGC

Downstream 100 bases:

>100_bases
GCTGCCTCAGGCGCGCGGATGGGCGGCGGCGTGGACTTCGCGCAGGCGCGAGGAGTCAATGCCGGTATAGACCTGCGTGG
TCGAAAGCGAAGCGTGGCCG

Product: putative oxygen-independent coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MTQVFAPFGPHFGFGLYIHWPYCTRVCPYCDFNVYAAKDRATDPLVTAIADDIRVHRRKLPEHGALDTVYFGGGTPALLR
PEQVAEILKAASETFGIKDGAEITLEANPNDVLKADLLALRRAGVTRLSIGVQSMRDSALAFLGRDHTAEAGGEAVKRAL
KVFDTISMDLIYARPGQSPANWEAELADALALGAPHLSLYELTFEPATAFGKAAQRGEIVPMPDDAQADLYELTQQMTRD
AGMPAYEVSNHAASPAHQSRHNLIYWRGGDWIGAGPGAHGRVSVAGNRYATEAERRPEGYMAGMQMLQEGWADAAKLPPL
DIAREILAMGLRAAEGVDLRRVEIVSGKKVSREKIGVFTEQGWVKLQGSELSLTESGRLLADALTSQLAP

Sequences:

>Translated_390_residues
MTQVFAPFGPHFGFGLYIHWPYCTRVCPYCDFNVYAAKDRATDPLVTAIADDIRVHRRKLPEHGALDTVYFGGGTPALLR
PEQVAEILKAASETFGIKDGAEITLEANPNDVLKADLLALRRAGVTRLSIGVQSMRDSALAFLGRDHTAEAGGEAVKRAL
KVFDTISMDLIYARPGQSPANWEAELADALALGAPHLSLYELTFEPATAFGKAAQRGEIVPMPDDAQADLYELTQQMTRD
AGMPAYEVSNHAASPAHQSRHNLIYWRGGDWIGAGPGAHGRVSVAGNRYATEAERRPEGYMAGMQMLQEGWADAAKLPPL
DIAREILAMGLRAAEGVDLRRVEIVSGKKVSREKIGVFTEQGWVKLQGSELSLTESGRLLADALTSQLAP
>Mature_389_residues
TQVFAPFGPHFGFGLYIHWPYCTRVCPYCDFNVYAAKDRATDPLVTAIADDIRVHRRKLPEHGALDTVYFGGGTPALLRP
EQVAEILKAASETFGIKDGAEITLEANPNDVLKADLLALRRAGVTRLSIGVQSMRDSALAFLGRDHTAEAGGEAVKRALK
VFDTISMDLIYARPGQSPANWEAELADALALGAPHLSLYELTFEPATAFGKAAQRGEIVPMPDDAQADLYELTQQMTRDA
GMPAYEVSNHAASPAHQSRHNLIYWRGGDWIGAGPGAHGRVSVAGNRYATEAERRPEGYMAGMQMLQEGWADAAKLPPLD
IAREILAMGLRAAEGVDLRRVEIVSGKKVSREKIGVFTEQGWVKLQGSELSLTESGRLLADALTSQLAP

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=301, Percent_Identity=36.5448504983389, Blast_Score=184, Evalue=1e-46,
Organism=Escherichia coli, GI1789325, Length=386, Percent_Identity=34.4559585492228, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI87082341, Length=303, Percent_Identity=25.4125412541254, Blast_Score=101, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 42309; Mature: 42178

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQVFAPFGPHFGFGLYIHWPYCTRVCPYCDFNVYAAKDRATDPLVTAIADDIRVHRRKL
CCCCCCCCCCCCCCEEEEECHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHC
PEHGALDTVYFGGGTPALLRPEQVAEILKAASETFGIKDGAEITLEANPNDVLKADLLAL
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHH
RRAGVTRLSIGVQSMRDSALAFLGRDHTAEAGGEAVKRALKVFDTISMDLIYARPGQSPA
HHCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCCC
NWEAELADALALGAPHLSLYELTFEPATAFGKAAQRGEIVPMPDDAQADLYELTQQMTRD
CCHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
AGMPAYEVSNHAASPAHQSRHNLIYWRGGDWIGAGPGAHGRVSVAGNRYATEAERRPEGY
CCCCCEECCCCCCCCCHHCCCCEEEEECCCEECCCCCCCCEEEECCCCCCCHHHHCCHHH
MAGMQMLQEGWADAAKLPPLDIAREILAMGLRAAEGVDLRRVEIVSGKKVSREKIGVFTE
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHCCEEEC
QGWVKLQGSELSLTESGRLLADALTSQLAP
CCEEEEECCEEEECCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TQVFAPFGPHFGFGLYIHWPYCTRVCPYCDFNVYAAKDRATDPLVTAIADDIRVHRRKL
CCCCCCCCCCCCCEEEEECHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHC
PEHGALDTVYFGGGTPALLRPEQVAEILKAASETFGIKDGAEITLEANPNDVLKADLLAL
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHH
RRAGVTRLSIGVQSMRDSALAFLGRDHTAEAGGEAVKRALKVFDTISMDLIYARPGQSPA
HHCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCCC
NWEAELADALALGAPHLSLYELTFEPATAFGKAAQRGEIVPMPDDAQADLYELTQQMTRD
CCHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
AGMPAYEVSNHAASPAHQSRHNLIYWRGGDWIGAGPGAHGRVSVAGNRYATEAERRPEGY
CCCCCEECCCCCCCCCHHCCCCEEEEECCCEECCCCCCCCEEEECCCCCCCHHHHCCHHH
MAGMQMLQEGWADAAKLPPLDIAREILAMGLRAAEGVDLRRVEIVSGKKVSREKIGVFTE
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHCCEEEC
QGWVKLQGSELSLTESGRLLADALTSQLAP
CCEEEEECCEEEECCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]