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The map label for this gene is pgk

Identifier: 114331566

GI number: 114331566

Start: 1658691

End: 1659869

Strand: Direct

Name: pgk

Synonym: Neut_1579

Alternate gene names: 114331566

Gene position: 1658691-1659869 (Clockwise)

Preceding gene: 114331565

Following gene: 114331567

Centisome position: 62.33

GC content: 44.78

Gene sequence:

>1179_bases
GTGTCAGTTATTAAACTTGTCGATCTAGATCTGAAGAATAAACGTGTTTTTATCCGCTCTGATCTGAATGTTCCTGTGAA
AGAAGGTAAGGTGACTTCAGATGCACGCATTACTGCATCCATGGCAACTATAAATCATTGCCTGAAGCAGGGAGCAAGAG
TAATGGTAACTTCCCATCTGGGGCGTCCGGAAGAAGGCGTGTGGGCCATGGAAAATTCTCTTCAGCCAGTTGCCAATGAT
ATTAGCCGGAGACTGGGAACAACTGTCCGATTGATCAAGGATTGGGTTGATGGTGGATTCGAAGTTGCGCCCGGAGAGCT
GGTAATTTTGGAAAATTGCCGAATTAATAAAGGTGAGAAAAAAAATCTTGAAGAAACAGCAAAAAAATATGCCAATTTGT
GTGATGTCTTTGTTATGGATGCTTTTGGTACAGCGCATCGTGCAGAAGCCTCAACACACGGTGTAGCCAAATATGCACCA
GTTGCTTGTGCTGGCATTTTACTTACCGAGGAATTGGATGCTTTAACCAAAGCCTTGCACCAGCCAGCACGCCCACTGGT
AGCAATTGTAGGAGGATCCAAAGTTTCCACCAAATTGACTGTTCTGGAATCACTTACTGAGAAAGTTGATCAACTTGTGG
TTGGTGGAGGAATTGCTAATACTTTCCTCAAGGCTGCTGGGAACAATGTTGGAAAGTCTCTGTGTGAGGATGAACTGGTA
CCTATAGCGAAATCCCTGATGGATAAAATGAATCAGCGTAATGCAACGATTCCCATCGCGATTGATGTCGTTGTCGGAAA
AAAATTTGCTGCAGATGAACCTGCTGTTCTAAAAGAAGCAAATGCTGTTTCCGATGATGACATGATTTTTGATATCGGCC
CCAAGAGCACTCAAGAACTGGTTAACATCATCATGAAGGCCGGCACAGTTGTCTGGAATGGCCCCGTTGGCGTGTTTGAA
TTTGATCAGTTTGGAGAAGGGACACACGCAATCGCCAAGGCAATTGCTGAAACTGATGCTTTCACCCTGGCAGGCGGTGG
TGACACGATTGCCGCCATTCAGAAGTATGATATTTACGATAAGGTTTCATACATATCCACTGCCGGAGGTGCATTCCTGG
AATTCTTAGAAGGAAAAAAACTACCCGCTGTCGAGATCCTGGAATTACGTGCACAGTGA

Upstream 100 bases:

>100_bases
ATGCATCTATATTTTTATCGTCCTTCTCAATTCAACAACTAATTAATTTCCATCTGATTATCTTATAAAATCAGCAAGTT
ATCTAAAATATGGAGCCAAT

Downstream 100 bases:

>100_bases
GGCCTGAGAAGATTTTCTTCCAGGAATTTCGGAAATGATGCGAAGAACAAAAATTGTAGCAACGCTGGGACCAGCTTCCA
GCAACCCTGATATCCTGAGA

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MSVIKLVDLDLKNKRVFIRSDLNVPVKEGKVTSDARITASMATINHCLKQGARVMVTSHLGRPEEGVWAMENSLQPVAND
ISRRLGTTVRLIKDWVDGGFEVAPGELVILENCRINKGEKKNLEETAKKYANLCDVFVMDAFGTAHRAEASTHGVAKYAP
VACAGILLTEELDALTKALHQPARPLVAIVGGSKVSTKLTVLESLTEKVDQLVVGGGIANTFLKAAGNNVGKSLCEDELV
PIAKSLMDKMNQRNATIPIAIDVVVGKKFAADEPAVLKEANAVSDDDMIFDIGPKSTQELVNIIMKAGTVVWNGPVGVFE
FDQFGEGTHAIAKAIAETDAFTLAGGGDTIAAIQKYDIYDKVSYISTAGGAFLEFLEGKKLPAVEILELRAQ

Sequences:

>Translated_392_residues
MSVIKLVDLDLKNKRVFIRSDLNVPVKEGKVTSDARITASMATINHCLKQGARVMVTSHLGRPEEGVWAMENSLQPVAND
ISRRLGTTVRLIKDWVDGGFEVAPGELVILENCRINKGEKKNLEETAKKYANLCDVFVMDAFGTAHRAEASTHGVAKYAP
VACAGILLTEELDALTKALHQPARPLVAIVGGSKVSTKLTVLESLTEKVDQLVVGGGIANTFLKAAGNNVGKSLCEDELV
PIAKSLMDKMNQRNATIPIAIDVVVGKKFAADEPAVLKEANAVSDDDMIFDIGPKSTQELVNIIMKAGTVVWNGPVGVFE
FDQFGEGTHAIAKAIAETDAFTLAGGGDTIAAIQKYDIYDKVSYISTAGGAFLEFLEGKKLPAVEILELRAQ
>Mature_391_residues
SVIKLVDLDLKNKRVFIRSDLNVPVKEGKVTSDARITASMATINHCLKQGARVMVTSHLGRPEEGVWAMENSLQPVANDI
SRRLGTTVRLIKDWVDGGFEVAPGELVILENCRINKGEKKNLEETAKKYANLCDVFVMDAFGTAHRAEASTHGVAKYAPV
ACAGILLTEELDALTKALHQPARPLVAIVGGSKVSTKLTVLESLTEKVDQLVVGGGIANTFLKAAGNNVGKSLCEDELVP
IAKSLMDKMNQRNATIPIAIDVVVGKKFAADEPAVLKEANAVSDDDMIFDIGPKSTQELVNIIMKAGTVVWNGPVGVFEF
DQFGEGTHAIAKAIAETDAFTLAGGGDTIAAIQKYDIYDKVSYISTAGGAFLEFLEGKKLPAVEILELRAQ

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family

Homologues:

Organism=Homo sapiens, GI31543397, Length=414, Percent_Identity=40.0966183574879, Blast_Score=277, Evalue=1e-74,
Organism=Homo sapiens, GI4505763, Length=414, Percent_Identity=39.1304347826087, Blast_Score=265, Evalue=6e-71,
Organism=Escherichia coli, GI1789294, Length=392, Percent_Identity=64.030612244898, Blast_Score=486, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI17508823, Length=405, Percent_Identity=40, Blast_Score=281, Evalue=6e-76,
Organism=Saccharomyces cerevisiae, GI6319857, Length=416, Percent_Identity=38.4615384615385, Blast_Score=268, Evalue=8e-73,
Organism=Drosophila melanogaster, GI17136394, Length=412, Percent_Identity=38.5922330097087, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24581203, Length=412, Percent_Identity=35.9223300970874, Blast_Score=236, Evalue=2e-62,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): PGK_NITEC (Q0AFQ9)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_747788.1
- ProteinModelPortal:   Q0AFQ9
- SMR:   Q0AFQ9
- STRING:   Q0AFQ9
- GeneID:   4272048
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_1579
- NMPDR:   fig|335283.3.peg.1883
- eggNOG:   COG0126
- HOGENOM:   HBG453500
- OMA:   CEESMID
- PhylomeDB:   Q0AFQ9
- ProtClustDB:   PRK00073
- BioCyc:   NEUT335283:NEUT_1579-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00145
- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824
- Gene3D:   G3DSA:3.40.50.1270
- Gene3D:   G3DSA:3.40.50.1260
- PANTHER:   PTHR11406
- PIRSF:   PIRSF000724
- PRINTS:   PR00477

Pfam domain/function: PF00162 PGK; SSF53748 PGK

EC number: =2.7.2.3

Molecular weight: Translated: 42032; Mature: 41901

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: BINDING 36-36 BINDING 114-114 BINDING 147-147 BINDING 198-198 BINDING 320-320

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVIKLVDLDLKNKRVFIRSDLNVPVKEGKVTSDARITASMATINHCLKQGARVMVTSHL
CCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECC
GRPEEGVWAMENSLQPVANDISRRLGTTVRLIKDWVDGGFEVAPGELVILENCRINKGEK
CCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCC
KNLEETAKKYANLCDVFVMDAFGTAHRAEASTHGVAKYAPVACAGILLTEELDALTKALH
CCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QPARPLVAIVGGSKVSTKLTVLESLTEKVDQLVVGGGIANTFLKAAGNNVGKSLCEDELV
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHH
PIAKSLMDKMNQRNATIPIAIDVVVGKKFAADEPAVLKEANAVSDDDMIFDIGPKSTQEL
HHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCHHHHHCCCCCCCCEEEECCCCCHHHH
VNIIMKAGTVVWNGPVGVFEFDQFGEGTHAIAKAIAETDAFTLAGGGDTIAAIQKYDIYD
HHHHHHCCCEEECCCCCEEECHHCCCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHCHHH
KVSYISTAGGAFLEFLEGKKLPAVEILELRAQ
HHHHHHHCHHHHHHHHCCCCCCHHHHHHCCCC
>Mature Secondary Structure 
SVIKLVDLDLKNKRVFIRSDLNVPVKEGKVTSDARITASMATINHCLKQGARVMVTSHL
CEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECC
GRPEEGVWAMENSLQPVANDISRRLGTTVRLIKDWVDGGFEVAPGELVILENCRINKGEK
CCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCC
KNLEETAKKYANLCDVFVMDAFGTAHRAEASTHGVAKYAPVACAGILLTEELDALTKALH
CCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QPARPLVAIVGGSKVSTKLTVLESLTEKVDQLVVGGGIANTFLKAAGNNVGKSLCEDELV
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHH
PIAKSLMDKMNQRNATIPIAIDVVVGKKFAADEPAVLKEANAVSDDDMIFDIGPKSTQEL
HHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCHHHHHCCCCCCCCEEEECCCCCHHHH
VNIIMKAGTVVWNGPVGVFEFDQFGEGTHAIAKAIAETDAFTLAGGGDTIAAIQKYDIYD
HHHHHHCCCEEECCCCCEEECHHCCCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHCHHH
KVSYISTAGGAFLEFLEGKKLPAVEILELRAQ
HHHHHHHCHHHHHHHHCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA