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The map label for this gene is gapA [H]

Identifier: 114331565

GI number: 114331565

Start: 1657365

End: 1658372

Strand: Direct

Name: gapA [H]

Synonym: Neut_1578

Alternate gene names: 114331565

Gene position: 1657365-1658372 (Clockwise)

Preceding gene: 114331564

Following gene: 114331566

Centisome position: 62.28

GC content: 43.25

Gene sequence:

>1008_bases
ATGGCAATTAGAGTTGGCATTAATGGTTTTGGTCGTATCGGACGGATGGTTTTTCGTGCTTCTATAGAAGAGTTTGATGA
CATAGAAGTTGTCGCAATCAACGATTTACTGGAACCGGATTATCTCGCCTATATGTTATTACATGATTCCGTTCATGGTC
GTTTCAAAGGAGATGTATCTGTTGACGGTAATAATTTGATAGTTAATGGCAAGAAAATTCGCTTAACTGCCACCAAGGAT
CCAGAAGAACTGAACTGGGGTGAAGTCAAGGTTGATGTCGTGGTGGAATCCACCGGATTGTTCCTGACCAAAGAACTCTG
TGAAAAACATATCAAGGCAGGCGCTCCTAAAGTCGTCATGACTGCGCCATCCAAGGATGATACGCCAATGTATGTTTATG
GTGTCAACGATAAAACATATCAGGGTGAAGCAATCATTTCCAATGCATCATGTACTACCAACTGCCTGGCCCCGATCGCA
AAAGTATTGAATGATACTTGGGGTATCAAGCGTGGTTTGATGACGACTGTTCATGCTGCCACGGCAACACAAAAAACAGT
TGATGGCCCTTCCAATAAAGATTGGCGTGGTGGACGCGGAATTCTCGAAAATATTATTCCTTCCTCTACGGGCGCAGCCA
AAGCAGTTGGTGTGGTTATTCCTGAATTAAATAAGAAGTTAACCGGCATGGCCTTTCGCGTACCCACTTCTGACGTCTCG
GTTGTAGATTTAACAGTGGAACTGGAAAAAGATGCATCTTACGACGAAATTCGTAAGGCAATGAAAACAGCTTCTGAAGG
CTCCATGAAAGGTGTATTAGGCTACACTGATCAAAAAGTGGTTTCCACTGATTTTCGTGGAGAAACCCATACATCAGTGT
TTGATGCAGAAGCCGGCATTCAGCTGGATAAGAATTTTGTGAAAGTTGTTGCCTGGTATGACAACGAATGGGGTTATTCC
TGCAAGGTACTGGAAATGGTACGAGTTATCGCTGGCCGTAATAATTAA

Upstream 100 bases:

>100_bases
TGAAAATGTCGTAAACGCGGTAAAAAGAATTATATAAACGCGGAAAGTTCTTTTCTTGTCTGCAAAACAGGTTTTTAGTA
AAAAATACGGAGATAAAGGG

Downstream 100 bases:

>100_bases
AGCTAAAGATATATTTTTCATGGAATAAACCACTGAGGTTGGTTGTTTATTTCTTACCCTGGAAATTGTGCTGTAACCAG
TTCCCTACTGGTTACAGCTT

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MAIRVGINGFGRIGRMVFRASIEEFDDIEVVAINDLLEPDYLAYMLLHDSVHGRFKGDVSVDGNNLIVNGKKIRLTATKD
PEELNWGEVKVDVVVESTGLFLTKELCEKHIKAGAPKVVMTAPSKDDTPMYVYGVNDKTYQGEAIISNASCTTNCLAPIA
KVLNDTWGIKRGLMTTVHAATATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAVGVVIPELNKKLTGMAFRVPTSDVS
VVDLTVELEKDASYDEIRKAMKTASEGSMKGVLGYTDQKVVSTDFRGETHTSVFDAEAGIQLDKNFVKVVAWYDNEWGYS
CKVLEMVRVIAGRNN

Sequences:

>Translated_335_residues
MAIRVGINGFGRIGRMVFRASIEEFDDIEVVAINDLLEPDYLAYMLLHDSVHGRFKGDVSVDGNNLIVNGKKIRLTATKD
PEELNWGEVKVDVVVESTGLFLTKELCEKHIKAGAPKVVMTAPSKDDTPMYVYGVNDKTYQGEAIISNASCTTNCLAPIA
KVLNDTWGIKRGLMTTVHAATATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAVGVVIPELNKKLTGMAFRVPTSDVS
VVDLTVELEKDASYDEIRKAMKTASEGSMKGVLGYTDQKVVSTDFRGETHTSVFDAEAGIQLDKNFVKVVAWYDNEWGYS
CKVLEMVRVIAGRNN
>Mature_334_residues
AIRVGINGFGRIGRMVFRASIEEFDDIEVVAINDLLEPDYLAYMLLHDSVHGRFKGDVSVDGNNLIVNGKKIRLTATKDP
EELNWGEVKVDVVVESTGLFLTKELCEKHIKAGAPKVVMTAPSKDDTPMYVYGVNDKTYQGEAIISNASCTTNCLAPIAK
VLNDTWGIKRGLMTTVHAATATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAVGVVIPELNKKLTGMAFRVPTSDVSV
VDLTVELEKDASYDEIRKAMKTASEGSMKGVLGYTDQKVVSTDFRGETHTSVFDAEAGIQLDKNFVKVVAWYDNEWGYSC
KVLEMVRVIAGRNN

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=333, Percent_Identity=57.0570570570571, Blast_Score=396, Evalue=1e-110,
Organism=Homo sapiens, GI7657116, Length=335, Percent_Identity=55.8208955223881, Blast_Score=385, Evalue=1e-107,
Organism=Escherichia coli, GI1788079, Length=331, Percent_Identity=70.392749244713, Blast_Score=474, Evalue=1e-135,
Organism=Escherichia coli, GI1789295, Length=335, Percent_Identity=37.3134328358209, Blast_Score=241, Evalue=6e-65,
Organism=Caenorhabditis elegans, GI17534677, Length=337, Percent_Identity=61.4243323442137, Blast_Score=410, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17534679, Length=337, Percent_Identity=61.4243323442137, Blast_Score=409, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17568413, Length=337, Percent_Identity=59.9406528189911, Blast_Score=399, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI32566163, Length=337, Percent_Identity=59.9406528189911, Blast_Score=399, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6322409, Length=331, Percent_Identity=62.5377643504532, Blast_Score=424, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6321631, Length=331, Percent_Identity=61.0271903323263, Blast_Score=414, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6322468, Length=331, Percent_Identity=59.8187311178248, Blast_Score=408, Evalue=1e-115,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=60.3076923076923, Blast_Score=396, Evalue=1e-110,
Organism=Drosophila melanogaster, GI17933600, Length=333, Percent_Identity=57.3573573573574, Blast_Score=396, Evalue=1e-110,
Organism=Drosophila melanogaster, GI18110149, Length=333, Percent_Identity=57.3573573573574, Blast_Score=396, Evalue=1e-110,
Organism=Drosophila melanogaster, GI85725000, Length=333, Percent_Identity=57.3573573573574, Blast_Score=395, Evalue=1e-110,
Organism=Drosophila melanogaster, GI22023983, Length=333, Percent_Identity=57.3573573573574, Blast_Score=395, Evalue=1e-110,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36585; Mature: 36454

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIRVGINGFGRIGRMVFRASIEEFDDIEVVAINDLLEPDYLAYMLLHDSVHGRFKGDVS
CEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHEEEEEECCCCCEEECEEE
VDGNNLIVNGKKIRLTATKDPEELNWGEVKVDVVVESTGLFLTKELCEKHIKAGAPKVVM
ECCCEEEEECCEEEEEECCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEE
TAPSKDDTPMYVYGVNDKTYQGEAIISNASCTTNCLAPIAKVLNDTWGIKRGLMTTVHAA
ECCCCCCCCEEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
TATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAVGVVIPELNKKLTGMAFRVPTSDVS
HCCHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCCEEEEEECCCCCCCCCEEEECCCCCCE
VVDLTVELEKDASYDEIRKAMKTASEGSMKGVLGYTDQKVVSTDFRGETHTSVFDAEAGI
EEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEECCCCCEEEEECCCCCCCCEEEECCCCC
QLDKNFVKVVAWYDNEWGYSCKVLEMVRVIAGRNN
EECCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AIRVGINGFGRIGRMVFRASIEEFDDIEVVAINDLLEPDYLAYMLLHDSVHGRFKGDVS
EEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHEEEEEECCCCCEEECEEE
VDGNNLIVNGKKIRLTATKDPEELNWGEVKVDVVVESTGLFLTKELCEKHIKAGAPKVVM
ECCCEEEEECCEEEEEECCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEE
TAPSKDDTPMYVYGVNDKTYQGEAIISNASCTTNCLAPIAKVLNDTWGIKRGLMTTVHAA
ECCCCCCCCEEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
TATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAVGVVIPELNKKLTGMAFRVPTSDVS
HCCHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCCEEEEEECCCCCCCCCEEEECCCCCCE
VVDLTVELEKDASYDEIRKAMKTASEGSMKGVLGYTDQKVVSTDFRGETHTSVFDAEAGI
EEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEECCCCCEEEEECCCCCCCCEEEECCCCC
QLDKNFVKVVAWYDNEWGYSCKVLEMVRVIAGRNN
EECCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852; 8366033 [H]