Click here to switch to the map view.

The map label for this gene is mlaA [H]

Identifier: 114331523

GI number: 114331523

Start: 1606129

End: 1606908

Strand: Reverse

Name: mlaA [H]

Synonym: Neut_1536

Alternate gene names: 114331523

Gene position: 1606908-1606129 (Counterclockwise)

Preceding gene: 114331524

Following gene: 114331521

Centisome position: 60.39

GC content: 44.74

Gene sequence:

>780_bases
ATGGTTGTTTGCTCTCTTTATTTCCGAAAATTTTTCGTGATTCTGTCATTAGGCAGCGCACTGTCAGGTTGTGCTACCAC
GGATAACCGGCACGATCCTTTGGAATCCATGAACCGCGCAATATTTTCATTTAATGAAAAGCTTGATGAAATTGTGGTGG
AGCCTGTTGCCAGGGGGTATCAGCGATTTCTACCATCTCCACTCAGAATGATTGTTGGAAACTTCTTTTCCAATCTTGAT
GATGTTGTCATTGTTGCGAACTCCCTGCTGCAGCTGAAATTTATGGACGCAATGGCGAGTACAACACGTGTAGTGATTAA
CACAACCTTTGGGATGTTGGGAGCTATTGATCTGGCCAGTGATATCACTCAGGTGAGCGATATTGACATCAATAAGCGCA
ATGAAGATTTTGGCCAAACATTGGGTTTTTATGGTGTTGGTAGCGGACCCTATCTTGTATTGCCGATACTAGGGCCCAGT
ACTGTAAGGGATGCAGTTGGGCTTGGTGTGGATAGCACGTTCATTCATCCTGCGCGAGCTATTTATACCGGCTTTGATCT
GCTGACTGTGCGTATGCCTGTTGCTACTATGGAATTTATCGATAGGCGTGAGCAGTTGCTGGATCTGGATAAGACGCTGG
AGGAAGCTTCGCTGGATAAGTACGAGTTTGTACGCGATGCTTATTTACAGAGGCGTGATAGCCTGATTCAAAACAACGGT
ACTTCATCTGCGGAAGAGTCAGTGGATTTTGATGACGAGGAAATAATCATTGATGATTGA

Upstream 100 bases:

>100_bases
CGTGAGGTTGGGTGCCGTTTATATTTTTCCAATCGGCTTGTTGCGATTCTTGTATTCGTGACAAAATGTCAAATTCATAA
TAAAGAATAATTAACGAATT

Downstream 100 bases:

>100_bases
TTCAATAAGATGGTTATTTACATTTTTGCCGGGGCTGGTGTAAGGATTCACCAGCCCCGGCTGCTCTATCATCAGGCAGA
TTGTAATGCCTGGATGCGCT

Product: VacJ family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MVVCSLYFRKFFVILSLGSALSGCATTDNRHDPLESMNRAIFSFNEKLDEIVVEPVARGYQRFLPSPLRMIVGNFFSNLD
DVVIVANSLLQLKFMDAMASTTRVVINTTFGMLGAIDLASDITQVSDIDINKRNEDFGQTLGFYGVGSGPYLVLPILGPS
TVRDAVGLGVDSTFIHPARAIYTGFDLLTVRMPVATMEFIDRREQLLDLDKTLEEASLDKYEFVRDAYLQRRDSLIQNNG
TSSAEESVDFDDEEIIIDD

Sequences:

>Translated_259_residues
MVVCSLYFRKFFVILSLGSALSGCATTDNRHDPLESMNRAIFSFNEKLDEIVVEPVARGYQRFLPSPLRMIVGNFFSNLD
DVVIVANSLLQLKFMDAMASTTRVVINTTFGMLGAIDLASDITQVSDIDINKRNEDFGQTLGFYGVGSGPYLVLPILGPS
TVRDAVGLGVDSTFIHPARAIYTGFDLLTVRMPVATMEFIDRREQLLDLDKTLEEASLDKYEFVRDAYLQRRDSLIQNNG
TSSAEESVDFDDEEIIIDD
>Mature_259_residues
MVVCSLYFRKFFVILSLGSALSGCATTDNRHDPLESMNRAIFSFNEKLDEIVVEPVARGYQRFLPSPLRMIVGNFFSNLD
DVVIVANSLLQLKFMDAMASTTRVVINTTFGMLGAIDLASDITQVSDIDINKRNEDFGQTLGFYGVGSGPYLVLPILGPS
TVRDAVGLGVDSTFIHPARAIYTGFDLLTVRMPVATMEFIDRREQLLDLDKTLEEASLDKYEFVRDAYLQRRDSLIQNNG
TSSAEESVDFDDEEIIIDD

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane [H]

COG id: COG2853

COG function: function code M; Surface lipoprotein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaA family [H]

Homologues:

Organism=Escherichia coli, GI1788688, Length=254, Percent_Identity=37.4015748031496, Blast_Score=134, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007428 [H]

Pfam domain/function: PF04333 VacJ [H]

EC number: NA

Molecular weight: Translated: 28866; Mature: 28866

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVCSLYFRKFFVILSLGSALSGCATTDNRHDPLESMNRAIFSFNEKLDEIVVEPVARGY
CEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRFLPSPLRMIVGNFFSNLDDVVIVANSLLQLKFMDAMASTTRVVINTTFGMLGAIDLAS
HHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHH
DITQVSDIDINKRNEDFGQTLGFYGVGSGPYLVLPILGPSTVRDAVGLGVDSTFIHPARA
HHHHHHCCCCCCCCCHHHHHCCCEECCCCCEEEEEECCCHHHHHHHHCCCCCHHHCHHHH
IYTGFDLLTVRMPVATMEFIDRREQLLDLDKTLEEASLDKYEFVRDAYLQRRDSLIQNNG
HHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
TSSAEESVDFDDEEIIIDD
CCCHHHCCCCCCCEEEECC
>Mature Secondary Structure
MVVCSLYFRKFFVILSLGSALSGCATTDNRHDPLESMNRAIFSFNEKLDEIVVEPVARGY
CEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRFLPSPLRMIVGNFFSNLDDVVIVANSLLQLKFMDAMASTTRVVINTTFGMLGAIDLAS
HHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHH
DITQVSDIDINKRNEDFGQTLGFYGVGSGPYLVLPILGPSTVRDAVGLGVDSTFIHPARA
HHHHHHCCCCCCCCCHHHHHCCCEECCCCCEEEEEECCCHHHHHHHHCCCCCHHHCHHHH
IYTGFDLLTVRMPVATMEFIDRREQLLDLDKTLEEASLDKYEFVRDAYLQRRDSLIQNNG
HHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
TSSAEESVDFDDEEIIIDD
CCCHHHCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]