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The map label for this gene is dppB [C]

Identifier: 114331432

GI number: 114331432

Start: 1526267

End: 1527244

Strand: Direct

Name: dppB [C]

Synonym: Neut_1443

Alternate gene names: 114331432

Gene position: 1526267-1527244 (Clockwise)

Preceding gene: 114331431

Following gene: 114331433

Centisome position: 57.36

GC content: 45.5

Gene sequence:

>978_bases
ATGCTAAATTACATTATTCGTCGGCTGTTTTATGCGATTCCGATACTTGTCGGCGTCAATCTCATCACATTTGCACTTTT
CTTTGTAGTGAACACTCCTGACGATATGGCTCGCATGCATCTGGGGACGAAACACGTTACAGAAGAAGCTATCTGGAAGT
GGAAACAAGAACATGGCTACAACAAACCCCTGCTCTACAACAACGTTGCTTACGGAATCGAGAAATTCACCGACACTATT
TTTTTTGAAAAATCCGTTTCGATGTTTGCTTTCGATTTTGGCCGTGCCGATGACGGGCGTGATATCGCTCATGAGATTCA
ATCACGCATGTGGCCCAGCCTGGCTATTGCGTTGCCTGTATTTCTGCTCGGGTTACTGGCCTACATTACTTTCGCATTGA
TAATGGTTTTCTTTCGGGCCACCTACATTGATTTTTGGGGCATCGTCCTGTGTGTCATGCTCATGTCCATCTCTAGCCTG
TTTTATATCATTGCCGGCCAATTTTTGATCGGCAAGCTATGGCACCTGGTGCCCATATCCGGATACGCCAGCGGGCTGGA
TGCCACCCGCTTCCTTTTGTTGCCCATTATTGTGGGTATCATCAGCAGTGCCGGCGCCAATACGCGCTGGTATCGCACCC
TTTTCCTGGAAGAAATCAATAAGGAATATGTACGTACTGCCCGAGCCAAGGGATTATCGGAAAATATAGTATTGTTCAGG
CATGTGCTCAAGAATGCAATGATCCCCATATTAACCGGGGCAGTTGTCGTCATTCCGCTGTTATTTCTTGGAGGACTGAT
TACTGAATCATTTTTTGGTATTCCTGGACTGGGCAGCTACACCATTGACGCTATTCAATCACAGGATTTTGCAGTAGTAC
GCGCAATGGTATTTCTGGGATCATTGTTGTATATCACAGGATTGGTACTGACAGATATTTCCTACACCTTTGCAGATCCA
AGAGTACGATTAGAATAA

Upstream 100 bases:

>100_bases
CATAGGAATAGTATTATTGATAATTATTCTATTCCCGGCGCGAGCAGCTTATCGCCGTAAAGAACAGCACAGAATATTGA
AAAACAGATAGCTTGATTCA

Downstream 100 bases:

>100_bases
TTATTTTTTTCTGTTGCTTGACCTCCTTTTCTCCGAGTAAATGACGATACTGCTGTAATTGGCATGAAATGCTGGCTGTA
ATAAATATCAAGCAATACTA

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MLNYIIRRLFYAIPILVGVNLITFALFFVVNTPDDMARMHLGTKHVTEEAIWKWKQEHGYNKPLLYNNVAYGIEKFTDTI
FFEKSVSMFAFDFGRADDGRDIAHEIQSRMWPSLAIALPVFLLGLLAYITFALIMVFFRATYIDFWGIVLCVMLMSISSL
FYIIAGQFLIGKLWHLVPISGYASGLDATRFLLLPIIVGIISSAGANTRWYRTLFLEEINKEYVRTARAKGLSENIVLFR
HVLKNAMIPILTGAVVVIPLLFLGGLITESFFGIPGLGSYTIDAIQSQDFAVVRAMVFLGSLLYITGLVLTDISYTFADP
RVRLE

Sequences:

>Translated_325_residues
MLNYIIRRLFYAIPILVGVNLITFALFFVVNTPDDMARMHLGTKHVTEEAIWKWKQEHGYNKPLLYNNVAYGIEKFTDTI
FFEKSVSMFAFDFGRADDGRDIAHEIQSRMWPSLAIALPVFLLGLLAYITFALIMVFFRATYIDFWGIVLCVMLMSISSL
FYIIAGQFLIGKLWHLVPISGYASGLDATRFLLLPIIVGIISSAGANTRWYRTLFLEEINKEYVRTARAKGLSENIVLFR
HVLKNAMIPILTGAVVVIPLLFLGGLITESFFGIPGLGSYTIDAIQSQDFAVVRAMVFLGSLLYITGLVLTDISYTFADP
RVRLE
>Mature_325_residues
MLNYIIRRLFYAIPILVGVNLITFALFFVVNTPDDMARMHLGTKHVTEEAIWKWKQEHGYNKPLLYNNVAYGIEKFTDTI
FFEKSVSMFAFDFGRADDGRDIAHEIQSRMWPSLAIALPVFLLGLLAYITFALIMVFFRATYIDFWGIVLCVMLMSISSL
FYIIAGQFLIGKLWHLVPISGYASGLDATRFLLLPIIVGIISSAGANTRWYRTLFLEEINKEYVRTARAKGLSENIVLFR
HVLKNAMIPILTGAVVVIPLLFLGGLITESFFGIPGLGSYTIDAIQSQDFAVVRAMVFLGSLLYITGLVLTDISYTFADP
RVRLE

Specific function: Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=352, Percent_Identity=27.2727272727273, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787053, Length=326, Percent_Identity=28.2208588957055, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788504, Length=318, Percent_Identity=27.0440251572327, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1787497, Length=325, Percent_Identity=23.3846153846154, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787550, Length=260, Percent_Identity=26.1538461538462, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1789888, Length=326, Percent_Identity=23.3128834355828, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787761, Length=136, Percent_Identity=31.6176470588235, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36714; Mature: 36714

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNYIIRRLFYAIPILVGVNLITFALFFVVNTPDDMARMHLGTKHVTEEAIWKWKQEHGY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHCCC
NKPLLYNNVAYGIEKFTDTIFFEKSVSMFAFDFGRADDGRDIAHEIQSRMWPSLAIALPV
CCCEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCHHHHHHHHH
FLLGLLAYITFALIMVFFRATYIDFWGIVLCVMLMSISSLFYIIAGQFLIGKLWHLVPIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GYASGLDATRFLLLPIIVGIISSAGANTRWYRTLFLEEINKEYVRTARAKGLSENIVLFR
HHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
HVLKNAMIPILTGAVVVIPLLFLGGLITESFFGIPGLGSYTIDAIQSQDFAVVRAMVFLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHH
SLLYITGLVLTDISYTFADPRVRLE
HHHHHHHHHHHHHHHHCCCCCEECC
>Mature Secondary Structure
MLNYIIRRLFYAIPILVGVNLITFALFFVVNTPDDMARMHLGTKHVTEEAIWKWKQEHGY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHCCC
NKPLLYNNVAYGIEKFTDTIFFEKSVSMFAFDFGRADDGRDIAHEIQSRMWPSLAIALPV
CCCEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCHHHHHHHHH
FLLGLLAYITFALIMVFFRATYIDFWGIVLCVMLMSISSLFYIIAGQFLIGKLWHLVPIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GYASGLDATRFLLLPIIVGIISSAGANTRWYRTLFLEEINKEYVRTARAKGLSENIVLFR
HHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
HVLKNAMIPILTGAVVVIPLLFLGGLITESFFGIPGLGSYTIDAIQSQDFAVVRAMVFLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHH
SLLYITGLVLTDISYTFADPRVRLE
HHHHHHHHHHHHHHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]