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The map label for this gene is hbpA [H]

Identifier: 114331431

GI number: 114331431

Start: 1524113

End: 1526257

Strand: Direct

Name: hbpA [H]

Synonym: Neut_1442

Alternate gene names: 114331431

Gene position: 1524113-1526257 (Clockwise)

Preceding gene: 114331425

Following gene: 114331432

Centisome position: 57.27

GC content: 46.34

Gene sequence:

>2145_bases
ATGCCGTGCCTGATACTATCCGGTTGTTCAGATGTCTGGAACAATCCATACCCGGATTCGGACTCTGGTAAAAACATTCT
TTACAATGCTTTTGCTGAGCGTCCCAAACACCTGGATCCCGTACAGTCGTACAGTTCGAATGAAATCCTGTTTACCGCCC
AGATTTATCAACCCCCCTTGCAATACCATTTCTTGAAACGACCGCTGACTCTGATTCCTCAAACAGCCAGCAAAATGCCC
GTTGTAAGCTATCAGGACGACAATGGCGTGCAACTGCCTCCCAATTCGGCTGGTGCTCATGTCGCCTACTCTGTTTATGA
AATCACCATCAGATCCGGTATTTTTTATCAACCTCACCCGGCATTCGCGCAGGATAAGCATCAACACCTGCTTTATCATG
CATTGACTCGGCAGGATATACAGACAGTCCAAAAAATCAGTGATTTTGAGCATACAGGAACACGAGAACTGATTGCCGAT
GACTTTATCTACCAGATCAAGCGACTGGCCCATCCTCGACTGCACTCCCCTATCTTTGGCTTGATGGCAGATTACATCAT
AGGGCTGCGCGAATATGCTGAAACTTTAAGAGATCAAGATAAAACCCAACCCCAAAACAGCTTCCTGGATTTACGCAAAT
TTCCTTTGGCCGGAGTCGAGCGGATAGATGATTACACTTACCGTATTCGTATCAAGGGTAAATATCCGCAATTTATCTAC
TGGCTAACCATGGCATTTTTTGCACCAGTTCCATGGGAAGCCGATCACTTCTTCTCACAACCGGGTATGGCCGAGAAGAA
TTTTACACTCGACTGGTACCCGGTTGGAACCGGTCCGTACATGCTAACTGAAAACAACCCGAACCAGATTATGGTGCTGG
AGCGCAACCCGAACTTCAAGGGCGAGTACTATCCGGATGAGGGTATGCCGGAAGATATGGAAAATGGCTTGCTGCGTGAT
GCCGGCAAAGCATTGCCATTCATAGATAAAATCATATTCAGCCGTGAAAAGGAAAGTATTCCCTACTGGAATAAATTTTT
ACAGGGATATTACGATGCCTCCAGTATTGGCTCGGACAGCTTTGATCAAGCGGTACAGATAACCGGACAAGGTGAAGCGG
CCATCACTGAAGAAATGGAGGCGCAAGGTATTCGTCTTGGAACAGAAGTAGCCCCATCCACCTATTACATGGGATTTAAT
ATGCTTGATCCGGTGGTAGGTGGCCGTACTCCTGAGGAAAAAGCGGCAGCGCGCAAACTGCGTCAGGCCATTTCTATAGC
CGTCAATTATGAAGAATTTTTGACCATCTTTGCCAATGGCCGTGGTATTGCTGCGCAAGGTCCCATTCCACCGGGCATTG
AAGGCTATCATGAAGGTGAAGCAGGCATAAATCCGATTTCCTATGAATGGCATAACGGGGAAGTTCGGCGCAAATCAATC
AAACAAGCACAAGCATTGCTTGCAGAAGCCGGTTATCCCGGGGGGATCAGTCGTAGAACCGGTAAACCGCTTGTACTGTA
TTATGACGTCACAGCACGTAGCGCAGATGACAGATCAATCATGGACTGGATGCGAATGCAGTTTCAGAAACTCAATATCC
AGCTGGTAGTACGCAGCACCGATTACAATCGTTTCCAAGACAAGATTCGCAAGGGGAACGCACAGATTTTTGAATGGGGC
TGGAATGCAGATTATCCGGATCCGGAAAACTTTCTGTTTTTATTGTACGGGCCGCAGCGCAAAGTGGATAACAGTGGTGA
AAATGCGGCCAATTACGATAATGCTGAATACAATCGGCTGTTCGAGCAGATGAAAAATATGGAACATGGCCCAGAGCGTA
TACAGATTATTGATCGGATGGTTGCTATTTTACGAGAAGACGCTCCCTGGCTATGGGGTTATCATCCAAAAATCTTCGCT
TTGTACCATGCCTGGTATCAGAATGTGAAACCTAACAGAATGGCGTACAACACAATCAAATATTACCGGATCAACCCTGA
ATTACGTGATCAGAAGCGCCATGAATGGAATACGCCGGTAGTATGGCCAATTGGCATAGGAATAGTATTATTGATAATTA
TTCTATTCCCGGCGCGAGCAGCTTATCGCCGTAAAGAACAGCACAGAATATTGAAAAACAGATAG

Upstream 100 bases:

>100_bases
AAACTGGATACGGGTAATTGACGCGAATTACCTTTCTGTACTGGCCGGCTTCTACCTGAAAATGAAACTTAATAAAATAA
TATGCCAGATCAGCTTGTTA

Downstream 100 bases:

>100_bases
CTTGATTCAATGCTAAATTACATTATTCGTCGGCTGTTTTATGCGATTCCGATACTTGTCGGCGTCAATCTCATCACATT
TGCACTTTTCTTTGTAGTGA

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 714; Mature: 713

Protein sequence:

>714_residues
MPCLILSGCSDVWNNPYPDSDSGKNILYNAFAERPKHLDPVQSYSSNEILFTAQIYQPPLQYHFLKRPLTLIPQTASKMP
VVSYQDDNGVQLPPNSAGAHVAYSVYEITIRSGIFYQPHPAFAQDKHQHLLYHALTRQDIQTVQKISDFEHTGTRELIAD
DFIYQIKRLAHPRLHSPIFGLMADYIIGLREYAETLRDQDKTQPQNSFLDLRKFPLAGVERIDDYTYRIRIKGKYPQFIY
WLTMAFFAPVPWEADHFFSQPGMAEKNFTLDWYPVGTGPYMLTENNPNQIMVLERNPNFKGEYYPDEGMPEDMENGLLRD
AGKALPFIDKIIFSREKESIPYWNKFLQGYYDASSIGSDSFDQAVQITGQGEAAITEEMEAQGIRLGTEVAPSTYYMGFN
MLDPVVGGRTPEEKAAARKLRQAISIAVNYEEFLTIFANGRGIAAQGPIPPGIEGYHEGEAGINPISYEWHNGEVRRKSI
KQAQALLAEAGYPGGISRRTGKPLVLYYDVTARSADDRSIMDWMRMQFQKLNIQLVVRSTDYNRFQDKIRKGNAQIFEWG
WNADYPDPENFLFLLYGPQRKVDNSGENAANYDNAEYNRLFEQMKNMEHGPERIQIIDRMVAILREDAPWLWGYHPKIFA
LYHAWYQNVKPNRMAYNTIKYYRINPELRDQKRHEWNTPVVWPIGIGIVLLIIILFPARAAYRRKEQHRILKNR

Sequences:

>Translated_714_residues
MPCLILSGCSDVWNNPYPDSDSGKNILYNAFAERPKHLDPVQSYSSNEILFTAQIYQPPLQYHFLKRPLTLIPQTASKMP
VVSYQDDNGVQLPPNSAGAHVAYSVYEITIRSGIFYQPHPAFAQDKHQHLLYHALTRQDIQTVQKISDFEHTGTRELIAD
DFIYQIKRLAHPRLHSPIFGLMADYIIGLREYAETLRDQDKTQPQNSFLDLRKFPLAGVERIDDYTYRIRIKGKYPQFIY
WLTMAFFAPVPWEADHFFSQPGMAEKNFTLDWYPVGTGPYMLTENNPNQIMVLERNPNFKGEYYPDEGMPEDMENGLLRD
AGKALPFIDKIIFSREKESIPYWNKFLQGYYDASSIGSDSFDQAVQITGQGEAAITEEMEAQGIRLGTEVAPSTYYMGFN
MLDPVVGGRTPEEKAAARKLRQAISIAVNYEEFLTIFANGRGIAAQGPIPPGIEGYHEGEAGINPISYEWHNGEVRRKSI
KQAQALLAEAGYPGGISRRTGKPLVLYYDVTARSADDRSIMDWMRMQFQKLNIQLVVRSTDYNRFQDKIRKGNAQIFEWG
WNADYPDPENFLFLLYGPQRKVDNSGENAANYDNAEYNRLFEQMKNMEHGPERIQIIDRMVAILREDAPWLWGYHPKIFA
LYHAWYQNVKPNRMAYNTIKYYRINPELRDQKRHEWNTPVVWPIGIGIVLLIIILFPARAAYRRKEQHRILKNR
>Mature_713_residues
PCLILSGCSDVWNNPYPDSDSGKNILYNAFAERPKHLDPVQSYSSNEILFTAQIYQPPLQYHFLKRPLTLIPQTASKMPV
VSYQDDNGVQLPPNSAGAHVAYSVYEITIRSGIFYQPHPAFAQDKHQHLLYHALTRQDIQTVQKISDFEHTGTRELIADD
FIYQIKRLAHPRLHSPIFGLMADYIIGLREYAETLRDQDKTQPQNSFLDLRKFPLAGVERIDDYTYRIRIKGKYPQFIYW
LTMAFFAPVPWEADHFFSQPGMAEKNFTLDWYPVGTGPYMLTENNPNQIMVLERNPNFKGEYYPDEGMPEDMENGLLRDA
GKALPFIDKIIFSREKESIPYWNKFLQGYYDASSIGSDSFDQAVQITGQGEAAITEEMEAQGIRLGTEVAPSTYYMGFNM
LDPVVGGRTPEEKAAARKLRQAISIAVNYEEFLTIFANGRGIAAQGPIPPGIEGYHEGEAGINPISYEWHNGEVRRKSIK
QAQALLAEAGYPGGISRRTGKPLVLYYDVTARSADDRSIMDWMRMQFQKLNIQLVVRSTDYNRFQDKIRKGNAQIFEWGW
NADYPDPENFLFLLYGPQRKVDNSGENAANYDNAEYNRLFEQMKNMEHGPERIQIIDRMVAILREDAPWLWGYHPKIFAL
YHAWYQNVKPNRMAYNTIKYYRINPELRDQKRHEWNTPVVWPIGIGIVLLIIILFPARAAYRRKEQHRILKNR

Specific function: Important role in heme acquisition or metabolism [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=501, Percent_Identity=21.5568862275449, Blast_Score=79, Evalue=9e-16,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 82515; Mature: 82383

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPCLILSGCSDVWNNPYPDSDSGKNILYNAFAERPKHLDPVQSYSSNEILFTAQIYQPPL
CCEEEEECCHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHCCCCCCEEEEEEECCCCH
QYHFLKRPLTLIPQTASKMPVVSYQDDNGVQLPPNSAGAHVAYSVYEITIRSGIFYQPHP
HHHHHHCCHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEEEEEEECCEEECCCC
AFAQDKHQHLLYHALTRQDIQTVQKISDFEHTGTRELIADDFIYQIKRLAHPRLHSPIFG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHH
LMADYIIGLREYAETLRDQDKTQPQNSFLDLRKFPLAGVERIDDYTYRIRIKGKYPQFIY
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHCCCEEEEEEEECCCCHHHH
WLTMAFFAPVPWEADHFFSQPGMAEKNFTLDWYPVGTGPYMLTENNPNQIMVLERNPNFK
HHHHHHHCCCCCCCHHHCCCCCCCCCCCEEEEEECCCCCEEEECCCCCEEEEEECCCCCC
GEYYPDEGMPEDMENGLLRDAGKALPFIDKIIFSREKESIPYWNKFLQGYYDASSIGSDS
CCCCCCCCCCHHHHCCHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHCCCCC
FDQAVQITGQGEAAITEEMEAQGIRLGTEVAPSTYYMGFNMLDPVVGGRTPEEKAAARKL
CCCEEEEECCCCHHHHHHHHHCCCEECCCCCCCEEEECCHHHHHHHCCCCCHHHHHHHHH
RQAISIAVNYEEFLTIFANGRGIAAQGPIPPGIEGYHEGEAGINPISYEWHNGEVRRKSI
HHHHHHEECHHHHEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHH
KQAQALLAEAGYPGGISRRTGKPLVLYYDVTARSADDRSIMDWMRMQFQKLNIQLVVRST
HHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEEC
DYNRFQDKIRKGNAQIFEWGWNADYPDPENFLFLLYGPQRKVDNSGENAANYDNAEYNRL
CCHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHH
FEQMKNMEHGPERIQIIDRMVAILREDAPWLWGYHPKIFALYHAWYQNVKPNRMAYNTIK
HHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHCCCCCCEEEEEEE
YYRINPELRDQKRHEWNTPVVWPIGIGIVLLIIILFPARAAYRRKEQHRILKNR
EEEECCHHHHCHHHCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PCLILSGCSDVWNNPYPDSDSGKNILYNAFAERPKHLDPVQSYSSNEILFTAQIYQPPL
CEEEEECCHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHCCCCCCEEEEEEECCCCH
QYHFLKRPLTLIPQTASKMPVVSYQDDNGVQLPPNSAGAHVAYSVYEITIRSGIFYQPHP
HHHHHHCCHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEEEEEEECCEEECCCC
AFAQDKHQHLLYHALTRQDIQTVQKISDFEHTGTRELIADDFIYQIKRLAHPRLHSPIFG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHH
LMADYIIGLREYAETLRDQDKTQPQNSFLDLRKFPLAGVERIDDYTYRIRIKGKYPQFIY
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHCCCEEEEEEEECCCCHHHH
WLTMAFFAPVPWEADHFFSQPGMAEKNFTLDWYPVGTGPYMLTENNPNQIMVLERNPNFK
HHHHHHHCCCCCCCHHHCCCCCCCCCCCEEEEEECCCCCEEEECCCCCEEEEEECCCCCC
GEYYPDEGMPEDMENGLLRDAGKALPFIDKIIFSREKESIPYWNKFLQGYYDASSIGSDS
CCCCCCCCCCHHHHCCHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHCCCCC
FDQAVQITGQGEAAITEEMEAQGIRLGTEVAPSTYYMGFNMLDPVVGGRTPEEKAAARKL
CCCEEEEECCCCHHHHHHHHHCCCEECCCCCCCEEEECCHHHHHHHCCCCCHHHHHHHHH
RQAISIAVNYEEFLTIFANGRGIAAQGPIPPGIEGYHEGEAGINPISYEWHNGEVRRKSI
HHHHHHEECHHHHEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHH
KQAQALLAEAGYPGGISRRTGKPLVLYYDVTARSADDRSIMDWMRMQFQKLNIQLVVRST
HHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEEC
DYNRFQDKIRKGNAQIFEWGWNADYPDPENFLFLLYGPQRKVDNSGENAANYDNAEYNRL
CCHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHH
FEQMKNMEHGPERIQIIDRMVAILREDAPWLWGYHPKIFALYHAWYQNVKPNRMAYNTIK
HHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHCCCCCCEEEEEEE
YYRINPELRDQKRHEWNTPVVWPIGIGIVLLIIILFPARAAYRRKEQHRILKNR
EEEECCHHHHCHHHCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]